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Cell Biology

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Biochemistry of the Cell

Cell pH and Organelle Balance

Description

Cell pH and organelle balance are essential for normal cell function. pH affects protein shape and activity, the charge on cell membranes, and many metabolic reactions inside the cell. Cells also use the proton motive force, which is the energy stored in a proton gradient, to make ATP, the cell’s main energy molecule.

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Transcript

pH 是溶液中 H+ 浓度的度量,用于表示其酸性或碱性的程度。

pH 值的范围为 0 到 14,其中 7 为中性,低于 7 的值为酸性,高于 7 的值为碱性。

细胞质的典型pH值处于7.0至7.4的微碱性范围内。细胞内pH值的显著变化可能影响关键的细胞过程,如代谢、膜电位和信号通路。

例如,细胞呼吸的终产物 CO2 与 H2O 结合形成 H2CO3

H2CO3 是一种弱酸,容易解离,使细胞质缓慢酸化,从而导致细胞应激。

因此,细胞通过离子交换器调节氢离子浓度来调控...

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