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Nucleophilic Substitution and Elimination Reactions of Alkyl Halides
SN2 Inversion of Configuration
Description
SN2 reactions cause inversion of configuration at the carbon being substituted. The nucleophile attacks from the back side, while the leaving group departs at the same time. This happens through a transition state, where the carbon changes from tetrahedral to trigonal bipyramidal and then back to tetrahedral.
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Transcript
Recordemos que una reacción SN2 sigue un mecanismo concertado, donde el ataque nucleofílico y la salida del grupo saliente ocurren simultáneamente.
La alta densidad de electrones alrededor del grupo saliente bloquea la parte frontal del sustrato, lo que obliga al nucleófilo a iniciar un ataque posterior.
A medida que el...
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