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Establishing a Diaphyseal Femur Fracture Model in Mice
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Biologia
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JoVE Journal Biologia
Establishing a Diaphyseal Femur Fracture Model in Mice

Establishing a Diaphyseal Femur Fracture Model in Mice

DOI:
10.3791/64766-v

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05:46 min

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December 09, 2022

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, ,
1Postgraduate Program in Biological Sciences – Biophysics, Institute of Biophysics Carlos Chagas Filho,Federal University of Rio de Janeiro, 2Postgraduate Program in Surgical Sciences, Faculty of Medicine,Federal University of Rio de Janeiro, 3Institute of Biomedical Sciences,Federal University of Rio de Janeiro

Capítulos

  • 00:00Introduction
  • 01:03Animal Preparation
  • 01:35Surgical Procedure
  • 03:55Results: Bone Fracture Patterns and Bone Fracture Healing
  • 05:21Conclusion

Summary

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This protocol describes a surgical procedure for the establishment of a diaphyseal fracture in the femur of mice, which is stabilized with an intramedullary wire, for fracture healing studies.

Tags

Diaphyseal Femur FractureMurine ModelOpen Surgery TechniqueLong-bone Fracture HealingLocal TransplantationIn Vivo TestingTherapeutic ComponentsStem CellsDrugsBiomaterialsAnesthesiaSurgical ProcedureIncisionMuscle DissectionPatella LuxationFemur ExposureFracture Induction

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