JoVE is the leading creator and publisher of video solutions that increase productivity in scientific research and education. JoVE has produced nearly 4,000 videos demonstrating experiments from laboratories at top research institutions and delivered online to millions of scientists, educators and students worldwide. JoVE institutional subscribers comprise nearly 800 universities, colleges, biotech and pharmaceutical companies, including such leaders as Harvard, MIT, Yale, Stanford, Princeton and Caltech. Headquartered in Cambridge, Massachusetts, JoVE maintains offices throughout the United States, Europe, Asia and Australia. Please visit www.jove.com to learn more.