Abigail González-Valdez Departamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas Universidad Nacional Autónoma de México Biography Publications Institution JoVE Articles Abigail González-Valdez has not added a biography. If you are Abigail González-Valdez and would like to personalize this page please email our Author Liaison for assistance. Publications Fused Enzyme Glucose-6-Phosphate Dehydrogenase::6-Phosphogluconolactonase (G6PD::6PGL) As a Potential Drug Target in , , and Microorganisms. Jan, 2024 | Pubmed ID: 38257939 The Alternative Sigma Factor RpoS Regulates Pseudomonas Aeruginosa Quorum Sensing Response by Repressing the PqsABCDE Operon and Activating Vfr Molecular Microbiology. Feb, 2024 | Pubmed ID: 38169053 Heterologous Production of Rhamnolipids in Pseudomonas Chlororaphis Subsp Chlororaphis ATCC 9446 Based on the Endogenous Production of N-acyl-homoserine Lactones Microbial Biotechnology. Jan, 2024 | Pubmed ID: 38041625 Strains Belonging to Phylogroup 3 Frequently Exhibit an Atypical Quorum Sensing Response: the Case of MAZ105, a Tomato Rhizosphere Isolate Microbiology (Reading, England). Oct, 2023 | Pubmed ID: 37819040 An Overall View of the Functional and Structural Characterization of Glucose-6-Phosphate Dehydrogenase Variants in the Mexican Population International Journal of Molecular Sciences. Aug, 2023 | Pubmed ID: 37628871 Nitazoxanide Inhibits the Bifunctional Enzyme GlG6PD::6PGL of : Biochemical and In Silico Characterization of a New Druggable Target International Journal of Molecular Sciences. Jul, 2023 | Pubmed ID: 37511272 Unraveling the Regulation of Pyocyanin Synthesis by RsmA Through MvaU and RpoS in Pseudomonas Aeruginosa ID4365 Journal of Basic Microbiology. Jan, 2023 | Pubmed ID: 36207285 Pyridyl Methylsulfinyl Benzimidazole Derivatives As Promising Agents Against and Molecules (Basel, Switzerland). Dec, 2022 | Pubmed ID: 36558035 G6PD::6PGL Fused Protein Inhibitors Decrease Trophozoite Viability: A New Alternative Against Giardiasis International Journal of Molecular Sciences. Nov, 2022 | Pubmed ID: 36430836 LasR Overexpression Leads to a RsaL-independent Pyocyanin Production Inhibition in a Low Phosphate Condition Microbiology (Reading, England). Oct, 2022 | Pubmed ID: 36301076 Biochemical and Kinetic Characterization of the Glucose-6-Phosphate Dehydrogenase from Strain 29CaP Microorganisms. Jul, 2022 | Pubmed ID: 35889079 COVID-19 in G6PD-deficient Patients, Oxidative Stress, and Neuropathology Current Topics in Medicinal Chemistry. 2022 | Pubmed ID: 35578850 Kinetic and Molecular Docking Studies to Determine the Effect of Inhibitors on the Activity and Structure of Fused G6PD::6PGL Protein from Molecules (Basel, Switzerland). Feb, 2022 | Pubmed ID: 35208965 Validation and Selection of New Reference Genes for RT-qPCR Analysis in Pediatric Glioma of Different Grades Genes. Aug, 2021 | Pubmed ID: 34573317 Identification and In Silico Characterization of Novel Glucose-6-Phosphate Dehydrogenase Inhibitors Molecules (Basel, Switzerland). Aug, 2021 | Pubmed ID: 34443540 Glucose-6-Phosphate Dehydrogenase::6-Phosphogluconolactonase from the Parasite . A Molecular and Biochemical Perspective of a Fused Enzyme Microorganisms. Aug, 2021 | Pubmed ID: 34442758 PqsR-independent Quorum-sensing Response of Pseudomonas Aeruginosa ATCC 9027 Outlier-strain Reveals New Insights on the PqsE Effect on RhlR Activity Molecular Microbiology. Oct, 2021 | Pubmed ID: 34418194 Cloning, Purification, and Characterization of the 6-phosphogluconate Dehydrogenase (6 PGDH) from Giardia Lamblia Molecular and Biochemical Parasitology. Jul, 2021 | Pubmed ID: 34048823 Novel Inhibitors of Human Glucose-6-phosphate Dehydrogenase (HsG6PD) Affect the Activity and Stability of the Protein Biochimica Et Biophysica Acta. General Subjects. Mar, 2021 | Pubmed ID: 33347959 Rhamnolipids Produced by Pseudomonas: from Molecular Genetics to the Market Microbial Biotechnology. Jan, 2021 | Pubmed ID: 33151628 Tracking the Genome of Four Isolates That Have a Defective Las Quorum-sensing System, but Are Still Virulent Access Microbiology. 2020 | Pubmed ID: 32974595 The Outlier Pseudomonas Aeruginosa Strain ATCC 9027 Harbors a Defective LasR Quorum-sensing Transcriptional Regulator FEMS Microbiology Letters. Aug, 2020 | Pubmed ID: 32691823 Characterizing the Fused TvG6PD::6PGL Protein from the Protozoan , and Effects of the NADP Molecule on Enzyme Stability International Journal of Molecular Sciences. Jul, 2020 | Pubmed ID: 32650494 Virulence Factors Regulation by the Quorum-sensing and Rsm Systems in the Marine Strain Pseudomonas Aeruginosa ID4365, a Natural Mutant in LasR FEMS Microbiology Letters. Jun, 2020 | Pubmed ID: 32501479 Rhamnolipids Stabilize Quorum Sensing Mediated Cooperation in Pseudomonas Aeruginosa FEMS Microbiology Letters. May, 2020 | Pubmed ID: 32407463 Effects of Single and Double Mutants in Human Glucose-6-Phosphate Dehydrogenase Variants Present in the Mexican Population: Biochemical and Structural Analysis International Journal of Molecular Sciences. Apr, 2020 | Pubmed ID: 32326520 Identification of the NADP Structural Binding Site and Coenzyme Effect on the Fused G6PD::6PGL Protein from Biomolecules. Dec, 2019 | Pubmed ID: 31892224 Gene Cloning, Recombinant Expression, Characterization, and Molecular Modeling of the Glycolytic Enzyme Triosephosphate Isomerase from Microorganisms. Dec, 2019 | Pubmed ID: 31878282 Molecular Cloning and Exploration of the Biochemical and Functional Analysis of Recombinant Glucose-6-Phosphate Dehydrogenase from PAL5 International Journal of Molecular Sciences. Oct, 2019 | Pubmed ID: 31652968 Two Pseudomonas Aeruginosa Clonal Groups Belonging to the PA14 Clade Are Indigenous to the Churince System in Cuatro Ciénegas Coahuila, México Environmental Microbiology. Aug, 2019 | Pubmed ID: 31112340 Biochemical Characterization and Structural Modeling of Fused Glucose-6-Phosphate Dehydrogenase-Phosphogluconolactonase from International Journal of Molecular Sciences. Aug, 2018 | Pubmed ID: 30149622 Cloning and Biochemical Characterization of Three Glucose‑6‑phosphate Dehydrogenase Mutants Presents in the Mexican Population International Journal of Biological Macromolecules. Nov, 2018 | Pubmed ID: 30096395 RNAi-Mediated Specific Gene Silencing As a Tool for the Discovery of New Drug Targets in Giardia Lamblia; Evaluation Using the NADH Oxidase Gene Genes. Nov, 2017 | Pubmed ID: 29099754 Biochemical Analysis of Two Single Mutants That Give Rise to a Polymorphic G6PD A-Double Mutant International Journal of Molecular Sciences. Oct, 2017 | Pubmed ID: 29072585 Purification, Concentration and Recovery of Small Fragments of DNA from Giardia Lamblia and Their Use for Other Molecular Techniques MethodsX. 2017 | Pubmed ID: 28948157 Pseudomonas Aeruginosa Quorum-sensing Response in the Absence of Functional LasR and LasI Proteins: the Case of Strain 148, a Virulent Dolphin Isolate FEMS Microbiology Letters. Jul, 2017 | Pubmed ID: 28591849 Glucose-6-Phosphate Dehydrogenase: Update and Analysis of New Mutations Around the World International Journal of Molecular Sciences. Dec, 2016 | Pubmed ID: 27941691 Pseudomonas Aeruginosa ATCC 9027 is a Non-virulent Strain Suitable for Mono-rhamnolipids Production Applied Microbiology and Biotechnology. Dec, 2016 | Pubmed ID: 27566690 Functional and Biochemical Characterization of Three Recombinant Human Glucose-6-Phosphate Dehydrogenase Mutants: Zacatecas, Vanua-Lava and Viangchan International Journal of Molecular Sciences. May, 2016 | Pubmed ID: 27213370 Mutations of Glucose-6-Phosphate Dehydrogenase Durham, Santa-Maria and A+ Variants Are Associated with Loss Functional and Structural Stability of the Protein International Journal of Molecular Sciences. Dec, 2015 | Pubmed ID: 26633385 High Variability in Quorum Quenching and Growth Inhibition by Furanone C-30 in Pseudomonas Aeruginosa Clinical Isolates from Cystic Fibrosis Patients Pathogens and Disease. Aug, 2015 | Pubmed ID: 26048733 The Oxidative Fermentation of Ethanol in Gluconacetobacter Diazotrophicus is a Two-step Pathway Catalyzed by a Single Enzyme: Alcohol-aldehyde Dehydrogenase (ADHa) International Journal of Molecular Sciences. Jan, 2015 | Pubmed ID: 25574602 The Stability of G6PD is Affected by Mutations with Different Clinical Phenotypes International Journal of Molecular Sciences. Nov, 2014 | Pubmed ID: 25407525 The Effect of Specific RhlA-las-box Mutations on DNA Binding and Gene Activation by Pseudomonas Aeruginosa Quorum-sensing Transcriptional Regulators RhlR and LasR FEMS Microbiology Letters. Jul, 2014 | Pubmed ID: 24935161 Pseudomonas Aeruginosa Clinical and Environmental Isolates Constitute a Single Population with High Phenotypic Diversity BMC Genomics. Apr, 2014 | Pubmed ID: 24773920 The Pseudomonas Aeruginosa RmlBDAC Operon, Encoding DTDP-L-rhamnose Biosynthetic Enzymes, is Regulated by the Quorum-sensing Transcriptional Regulator RhlR and the Alternative Sigma Factor σS Microbiology (Reading, England). Apr, 2012 | Pubmed ID: 22262098 Transcriptional Regulation of Pseudomonas Aeruginosa RhlR: Role of the CRP Orthologue Vfr (virulence Factor Regulator) and Quorum-sensing Regulators LasR and RhlR Microbiology (Reading, England). Sep, 2011 | Pubmed ID: 21719541 Author Spotlight: Understanding Rhamnolipid Regulation in Pseudomonas aeruginosa Abigail González-Valdez1, Jessica Hernández-Pineda2, Gloria Soberón-Chávez1 1Departamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, 2Departamento de Infectología e Inmunología, Instituto Nacional de Perinatología JoVE 65934 Biochemistry
Author Spotlight: Understanding Rhamnolipid Regulation in Pseudomonas aeruginosa Abigail González-Valdez1, Jessica Hernández-Pineda2, Gloria Soberón-Chávez1 1Departamento de Biología Molecular y Biotecnología, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, 2Departamento de Infectología e Inmunología, Instituto Nacional de Perinatología JoVE 65934 Biochemistry