Akira Miyazaki

Department of Biochemistry, Showa University School of Medicine

Affiliated withShowa University School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 1	2019

Other Publications

Article	Year
Advanced glycation end products (AGE) inhibit scavenger receptor class B type I-mediated reverse cholesterol transport: a new crossroad of AGE to cholesterol metabolism. Journal of atherosclerosis and thrombosis\| PubMed ID: 12621157	2003
Acyl-coenzyme A:cholesterol acyltransferase inhibitors for controlling hypercholesterolemia and atherosclerosis. Current opinion in investigational drugs (London, England : 2000)\| PubMed ID: 14582454	2003
Genomic organization, expression, and comparative analysis of noncoding region of the rat Ndrg4 gene. Gene\| PubMed ID: 14693380	2004
[Acyl-coenzyme A: cholesterol acyltransferase (ACAT)]. Nihon rinsho. Japanese journal of clinical medicine\| PubMed ID: 15658270	2004
High prevalence of Chlamydia pneumoniae antibodies and increased high-sensitive C-reactive protein in patients with vascular dementia. Journal of the American Geriatrics Society\| PubMed ID: 15817002	2005
Serotonin acts as an up-regulator of acyl-coenzyme A:cholesterol acyltransferase-1 in human monocyte-macrophages. Atherosclerosis\| PubMed ID: 16157345	2006
Human urotensin II accelerates foam cell formation in human monocyte-derived macrophages. Hypertension (Dallas, Tex. : 1979)\| PubMed ID: 16172428	2005
Relationship between serum insulin-like growth factor-1 levels and Alzheimer's disease and vascular dementia. Journal of the American Geriatrics Society\| PubMed ID: 16181175	2005
Ndrg4 enhances NGF-induced ERK activation uncoupled with Elk-1 activation. Journal of cellular biochemistry\| PubMed ID: 16408304	2006
Inhibitors of acyl-coenzyme a: cholesterol acyltransferase. Current drug targets. Cardiovascular & haematological disorders\| PubMed ID: 16503866	2005
Human urotensin II as a link between hypertension and coronary artery disease. Hypertension research : official journal of the Japanese Society of Hypertension\| PubMed ID: 16940699	2006
Impact of increased plasma serotonin levels and carotid atherosclerosis on vascular dementia. Atherosclerosis\| PubMed ID: 17049533	2007
Increased human urotensin II levels are correlated with carotid atherosclerosis in essential hypertension. American journal of hypertension\| PubMed ID: 17261470	2007
Human urotensin-II potentiates the mitogenic effect of mildly oxidized low-density lipoprotein on vascular smooth muscle cells: comparison with other vasoactive agents and hydrogen peroxide. Hypertension research : official journal of the Japanese Society of Hypertension\| PubMed ID: 17283870	2006
Use of serum insulin-like growth factor-I levels to predict psychiatric non-response to donepezil in patients with Alzheimer's disease. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society\| PubMed ID: 17714966	2008
Impact of salusin-alpha and -beta on human macrophage foam cell formation and coronary atherosclerosis. Circulation\| PubMed ID: 18212280	2008
Increased plasma urotensin-II levels are associated with diabetic retinopathy and carotid atherosclerosis in Type 2 diabetes. Clinical science (London, England : 1979)\| PubMed ID: 18338983	2008
Serum salusin-alpha levels are decreased and correlated negatively with carotid atherosclerosis in essential hypertensive patients. Hypertension research : official journal of the Japanese Society of Hypertension\| PubMed ID: 18497465	2008
Chronic urotensin II infusion enhances macrophage foam cell formation and atherosclerosis in apolipoprotein E-knockout mice. Journal of hypertension\| PubMed ID: 18806619	2008
Angiotensin II upregulates acyl-CoA:cholesterol acyltransferase-1 via the angiotensin II Type 1 receptor in human monocyte-macrophages. Hypertension research : official journal of the Japanese Society of Hypertension\| PubMed ID: 18971559	2008
Human urotensin II promotes hypertension and atherosclerotic cardiovascular diseases. Current medicinal chemistry\| PubMed ID: 19199921	2009
Leptin modulates ACAT1 expression and cholesterol efflux from human macrophages. American journal of physiology. Endocrinology and metabolism\| PubMed ID: 19625677	2009
Increased plasma urotensin-II and carotid atherosclerosis are associated with vascular dementia. Journal of atherosclerosis and thrombosis\| PubMed ID: 19638714	2009
Preventive effects of heregulin-beta1 on macrophage foam cell formation and atherosclerosis. Circulation research\| PubMed ID: 19644050	2009
Chronic infusion of salusin-alpha and -beta exerts opposite effects on atherosclerotic lesion development in apolipoprotein E-deficient mice. Atherosclerosis\| PubMed ID: 20684826	2010
Purification of recombinant acyl-coenzyme A:cholesterol acyltransferase 1 (ACAT1) from H293 cells and binding studies between the enzyme and substrates using difference intrinsic fluorescenc... Biochemistry\| PubMed ID: 20964445	2010
m-Calpain induction in vascular endothelial cells on human and mouse atheromas and its roles in VE-cadherin disorganization and atherosclerosis. Circulation\| PubMed ID: 22064597	2011
Effects of PKF275-055, a dipeptidyl peptidase-4 inhibitor, on the development of atherosclerotic lesions in apolipoprotein E-null mice. Metabolism: clinical and experimental\| PubMed ID: 22225957	2012
Hydrogen peroxide-inducible clone 5 (Hic-5) as a potential therapeutic target for vascular and other disorders. Journal of atherosclerosis and thrombosis\| PubMed ID: 22472216	2012
Coexpression of CCR6 and CD146 (MCAM) is a marker of effector memory T-helper 17 cells. The Journal of dermatology\| PubMed ID: 22486269	2012
Salusin-β accelerates inflammatory responses in vascular endothelial cells via NF-κB signaling in LDL receptor-deficient mice in vivo and HUVECs in vitro. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 22561298	2012
Calpain and atherosclerosis. Journal of atherosclerosis and thrombosis\| PubMed ID: 23171729	2013
Time course-changes in phosphatidylcholine profile during oxidative modification of low-density lipoprotein. Lipids in health and disease\| PubMed ID: 24625108	2014
Identification of Hic-5 as a novel scaffold for the MKK4/p54 JNK pathway in the development of abdominal aortic aneurysms. Journal of the American Heart Association\| PubMed ID: 24811612	2014
NADPH oxidase deficiency exacerbates angiotensin II-induced abdominal aortic aneurysms in mice. Arteriosclerosis, thrombosis, and vascular biology\| PubMed ID: 25189573	2014
Role of Hic-5 in the formation of microvilli-like structures and the monocyte-endothelial interaction that accelerates atherosclerosis. Cardiovascular research\| PubMed ID: 25587044	2015
Calpastatin counteracts pathological angiogenesis by inhibiting suppressor of cytokine signaling 3 degradation in vascular endothelial cells. Circulation research\| PubMed ID: 25648699	2015
Hydrogen peroxide-inducible clone-5 regulates mesangial cell proliferation in proliferative glomerulonephritis in mice. PloS one\| PubMed ID: 25835392	2015
Hic-5 deficiency attenuates the activation of hepatic stellate cells and liver fibrosis through upregulation of Smad7 in mice. Journal of hepatology\| PubMed ID: 26334580	2016
Fibroblast growth factor-23 induces cellular senescence in human mesenchymal stem cells from skeletal muscle. Biochemical and biophysical research communications\| PubMed ID: 26797283	2016
Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Is Involved in Adult Mouse Hippocampal Neurogenesis After Stroke. Journal of molecular neuroscience : MN\| PubMed ID: 26910758	2016
Functional Heterogeneity of Nadph Oxidases in Atherosclerotic and Aneurysmal Diseases. Journal of atherosclerosis and thrombosis\| PubMed ID: 27476665	2017
Calpain-6 confers atherogenicity to macrophages by dysregulating pre-mRNA splicing. The Journal of clinical investigation\| PubMed ID: 27525442	2016
Potential contribution of the hepcidin-macrophage axis to plaque vulnerability in acute myocardial infarction in human. International journal of cardiology\| PubMed ID: 27855289	2017
Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells. Scientific reports\| PubMed ID: 28150810	2017
Emerging roles of calpain proteolytic systems in macrophage cholesterol handling. Cellular and molecular life sciences : CMLS\| PubMed ID: 28432377	2017
Dysregulation of Calpain Proteolytic Systems Underlies Degenerative Vascular Disorders. Journal of atherosclerosis and thrombosis\| PubMed ID: 28819082	2018
The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling. Oncogene\| PubMed ID: 29242607	2018
Expression of steroidogenic enzymes and metabolism of steroids in COS-7 cells known as non-steroidogenic cells. Scientific reports\| PubMed ID: 29391479	2018
Impact of Dysfunctional Protein Catabolism on Macrophage Cholesterol Handling. Current medicinal chemistry\| PubMed ID: 29589525	2019
Endothelial calpain systems orchestrate myofibroblast differentiation during wound healing. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 30199285	2019
Thrombolytic Therapy for Acute Ischemic Stroke: Past and Future. Current pharmaceutical design\| PubMed ID: 30892155	2019
Priming with erythropoietin enhances cell survival and angiogenic effect of mesenchymal stem cell implantation in rat limb ischemia. Regenerative therapy\| PubMed ID: 31245482	2016