Alfredo Nicosia

Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II

Affiliated withUniversity of Naples Federico II University of Naples Federico II CEINGE Biotecnologie Avanzate Franco Salvatore S.C.aR.L.

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 12	2021
Publication title	2025

Other Publications

Article	Year
Hepatitis C virus-multispecific T-cell responses without viremia or seroconversion among Egyptian health care workers at high risk of infection. Clinical and vaccine immunology : CVI\| PubMed ID: 22441392	2012
ChAd63-MVA-vectored blood-stage malaria vaccines targeting MSP1 and AMA1: assessment of efficacy against mosquito bite challenge in humans. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 23089736	2012
Comparative analysis of the magnitude, quality, phenotype, and protective capacity of simian immunodeficiency virus gag-specific CD8+ T cells following human-, simian-, and chimpanzee-derive... Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 23390298	2013
Vaccination to conserved influenza antigens in mice using a novel Simian adenovirus vector, PanAd3, derived from the bonobo Pan paniscus. PloS one\| PubMed ID: 23536756	2013
Vaccine-elicited human T cells recognizing conserved protein regions inhibit HIV-1. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 24166483	2014
Hypervariable region 1 deletion and required adaptive envelope mutations confer decreased dependency on scavenger receptor class B type I and low-density lipoprotein receptor for hepatitis C... Journal of virology\| PubMed ID: 24257605	2014
Protective CD8+ T-cell immunity to human malaria induced by chimpanzee adenovirus-MVA immunisation. Nature communications\| PubMed ID: 24284865	2013
Fusion of HCV nonstructural antigen to MHC class II-associated invariant chain enhances T-cell responses induced by vectored vaccines in nonhuman primates. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 24476798	2014
Combined adenovirus vector and hepatitis C virus envelope protein prime-boost regimen elicits T cell and neutralizing antibody immune responses. Journal of virology\| PubMed ID: 24599994	2014
Adenovirus type 4 and 7 vaccination or adenovirus type 4 respiratory infection elicits minimal cross-reactive antibody responses to nonhuman adenovirus vaccine vectors. Clinical and vaccine immunology : CVI\| PubMed ID: 24623627	2014
Production and characterization of high-titer serum-free cell culture grown hepatitis C virus particles of genotype 1-6. Virology\| PubMed ID: 24928051	2014
Enhanced vaccine-induced CD8+ T cell responses to malaria antigen ME-TRAP by fusion to MHC class ii invariant chain. PloS one\| PubMed ID: 24945248	2014
T-cell immunity and hepatitis C virus reinfection after cure of chronic hepatitis C with an interferon-free antiviral regimen in a chimpanzee. Hepatology (Baltimore, Md.)\| PubMed ID: 24975498	2014
Role of hypervariable region 1 for the interplay of hepatitis C virus with entry factors and lipoproteins. Journal of virology\| PubMed ID: 25142595	2014
Combining viral vectored and protein-in-adjuvant vaccines against the blood-stage malaria antigen AMA1: report on a phase 1a clinical trial. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 25156127	2014
Chimpanzee adenovirus vaccine generates acute and durable protective immunity against ebolavirus challenge. Nature medicine\| PubMed ID: 25194571	2014
Evaluation of the efficacy of ChAd63-MVA vectored vaccines expressing circumsporozoite protein and ME-TRAP against controlled human malaria infection in malaria-naive individuals. The Journal of infectious diseases\| PubMed ID: 25336730	2015
Dramatic potentiation of the antiviral activity of HIV antibodies by cholesterol conjugation. The Journal of biological chemistry\| PubMed ID: 25342747	2014
A human vaccine strategy based on chimpanzee adenoviral and MVA vectors that primes, boosts, and sustains functional HCV-specific T cell memory. Science translational medicine\| PubMed ID: 25378645	2014
Chimpanzee Adenovirus Vector Ebola Vaccine. The New England journal of medicine\| PubMed ID: 25426834	2017
A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA. The New England journal of medicine\| PubMed ID: 25629663	2016
Antigen expression determines adenoviral vaccine potency independent of IFN and STING signaling. The Journal of clinical investigation\| PubMed ID: 25642773	2015
Anti-CD81 but not anti-SR-BI blocks Plasmodium falciparum liver infection in a humanized mouse model. The Journal of antimicrobial chemotherapy\| PubMed ID: 25656410	2015
Prime-boost vaccination with chimpanzee adenovirus and modified vaccinia Ankara encoding TRAP provides partial protection against Plasmodium falciparum infection in Kenyan adults. Science translational medicine\| PubMed ID: 25947165	2015
Chimpanzee adenovirus- and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults. Science translational medicine\| PubMed ID: 26268313	2015
Cholesterol conjugation potentiates the antiviral activity of an HIV immunoadhesin. Journal of peptide science : an official publication of the European Peptide Society\| PubMed ID: 26292842	2015
Targeting a host-cell entry factor barricades antiviral-resistant HCV variants from on-therapy breakthrough in human-liver mice. Gut\| PubMed ID: 26306759	2016
Chronic hepatitis C viral infection subverts vaccine-induced T-cell immunity in humans. Hepatology (Baltimore, Md.)\| PubMed ID: 26474390	2016
Persistent HCV replication despite priming of functional CD8+ T cells by combined therapy with a vaccine and direct acting antiviral. Hepatology (Baltimore, Md.)\| PubMed ID: 26513111	2015
Novel human anti-claudin 1 mAbs inhibit hepatitis C virus infection and may synergize with anti-SRB1 mAb. The Journal of general virology\| PubMed ID: 26519290	2016
Safety and Immunogenicity of ChAd63 and MVA ME-TRAP in West African Children and Infants. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 27109630	2016
Highly-Immunogenic Virally-Vectored T-cell Vaccines Cannot Overcome Subversion of the T-cell Response by HCV during Chronic Infection. Vaccines\| PubMed ID: 27490575	2016
Therapeutic Vaccine Against Primate Papillomavirus Infections of the Cervix. Journal of immunotherapy (Hagerstown, Md. : 1997)\| PubMed ID: 28166180	2017
Mucosal Vaccination with Heterologous Viral Vectored Vaccine Targeting Subdominant SIV Accessory Antigens Strongly Inhibits Early Viral Replication. EBioMedicine\| PubMed ID: 28302457	2017
Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies. JCI insight\| PubMed ID: 28614791	2017
Chimpanzee adenoviral vectors as vaccines - challenges to move the technology into the fast lane. Expert review of vaccines\| PubMed ID: 29047309	2017
Incidence and Risk Factors for Hepatitis C Virus Infection among Illicit Drug Users in Italy. Journal of urban health : bulletin of the New York Academy of Medicine\| PubMed ID: 29204843	2018
Assessment of novel vaccination regimens using viral vectored liver stage malaria vaccines encoding ME-TRAP. Scientific reports\| PubMed ID: 29467399	2018
Immune Profiling of Premalignant Lesions in Patients With Lynch Syndrome. JAMA oncology\| PubMed ID: 29710228	2018
Massive parallel screening of phage libraries for the generation of repertoires of human immunomodulatory monoclonal antibodies. mAbs\| PubMed ID: 29995563	2018
Antigen-specific CD8 T cells in cell cycle circulate in the blood after vaccination. Scandinavian journal of immunology\| PubMed ID: 30488973	2019
A Novel Vaccine Strategy Employing Serologically Different Chimpanzee Adenoviral Vectors for the Prevention of HIV-1 and HCV Coinfection. Frontiers in immunology\| PubMed ID: 30713538	2018
Novel genetically-modified chimpanzee adenovirus and MVA-vectored respiratory syncytial virus vaccine safely boosts humoral and cellular immunity in healthy older adults. The Journal of infection\| PubMed ID: 30742894	2019
Longitudinal transcriptomic and genetic landscape of radiotherapy response in canine melanoma. Veterinary and comparative oncology\| PubMed ID: 30805995	2019
Adenoviral vaccine targeting multiple neoantigens as strategy to eradicate large tumors combined with checkpoint blockade. Nature communications\| PubMed ID: 31217437	2019
Novel Human Anti-PD-L1 mAbs Inhibit Immune-Independent Tumor Cell Growth and PD-L1 Associated Intracellular Signalling. Scientific reports\| PubMed ID: 31511565	2019
Rapid Affinity Maturation of Novel Anti-PD-L1 Antibodies by a Fast Drop of the Antigen Concentration and FACS Selection of Yeast Libraries. BioMed research international\| PubMed ID: 31976323	2019
MHC class II invariant chain-adjuvanted viral vectored vaccines enhances T cell responses in humans. Science translational medicine\| PubMed ID: 32554708	2020
A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability. Cancer research\| PubMed ID: 32690723	2020
Isolation of Two Novel Human Anti-CTLA-4 mAbs with Intriguing Biological Properties on Tumor and NK Cells. Cancers\| PubMed ID: 32781690	2020
Optimising T cell (re)boosting strategies for adenoviral and modified vaccinia Ankara vaccine regimens in humans. NPJ vaccines\| PubMed ID: 33083029	2020
Integrity of the Antiviral STING-mediated DNA Sensing in Tumor Cells Is Required to Sustain the Immunotherapeutic Efficacy of Oncolytic Virus. Cancers\| PubMed ID: 33213060	2020
New viral vectors for infectious diseases and cancer. Seminars in immunology\| PubMed ID: 33262065	2020
Peptide nucleic acid-mediated circularization of target RNA as tool to inhibit translation. International journal of biological macromolecules\| PubMed ID: 40118420	2025