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In JoVE (1)
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Articles by Alisa B. Schiffman in JoVE
JoVE General
Immunofluorescentie detectie van twee thymidine-analogen (CldU en IDU) in het jeugdwerk Tissue
We hebben afgeleid van een strategie om sequentiële opname van thymidine-analogen (CldU en IDU) op te sporen in de weefsels van volwassen muizen om twee opeenvolgende rondes van celdeling te kwantificeren. Deze strategie is nuttig om de celvernieuwing van de langlevende weefsels, oncogene transformatie, of transit-amplificerende cellen te detecteren.
Other articles by Alisa B. Schiffman on PubMed
Extremes of Clinical and Enzymatic Phenotypes in Children with Hyperinsulinism Caused by Glucokinase Activating Mutations
Heterozygous activating mutations of glucokinase have been reported to cause hypoglycemia attributable to hyperinsulinism in a limited number of families. We report three children with de novo glucokinase hyperinsulinism mutations who displayed a spectrum of clinical phenotypes corresponding to marked differences in enzyme kinetics.
