Alyssa H. Hasty Department of Molecular Physiology and Biophysics Vanderbilt University School of Medicine Biography Publications Institution JoVE Articles Alyssa H. Hasty has not added a biography. If you are Alyssa H. Hasty and would like to personalize this page please email our Author Liaison for assistance. Publications Endoplasmic Reticulum Stress and Hypertension - a New Paradigm? The Journal of Clinical Investigation. Nov, 2012 | Pubmed ID: 23064369 Toll-like Receptor 4 Deficiency Promotes the Alternative Activation of Adipose Tissue Macrophages Diabetes. Nov, 2012 | Pubmed ID: 22751700 Stearic Acid Accumulation in Macrophages Induces Toll-like Receptor 4/2-independent Inflammation Leading to Endoplasmic Reticulum Stress-mediated Apoptosis Arteriosclerosis, Thrombosis, and Vascular Biology. Jul, 2012 | Pubmed ID: 22556332 Impact of Macrophage Inflammatory Protein-1α Deficiency on Atherosclerotic Lesion Formation, Hepatic Steatosis, and Adipose Tissue Expansion PloS One. 2012 | Pubmed ID: 22359597 Haematopoietic Leptin Receptor Deficiency Does Not Affect Macrophage Accumulation in Adipose Tissue or Systemic Insulin Sensitivity The Journal of Endocrinology. Mar, 2012 | Pubmed ID: 22194312 Aberrant Accumulation of Undifferentiated Myeloid Cells in the Adipose Tissue of CCR2-deficient Mice Delays Improvements in Insulin Sensitivity Diabetes. Nov, 2011 | Pubmed ID: 21926275 The Role of Adipose Tissue in Mediating the Beneficial Effects of Dietary Fish Oil The Journal of Nutritional Biochemistry. Feb, 2011 | Pubmed ID: 21145721 Absence of Macrophage Inflammatory Protein-1{alpha} Does Not Impact Macrophage Accumulation in Adipose Tissue of Diet-induced Obese Mice American Journal of Physiology. Endocrinology and Metabolism. Sep, 2010 | Pubmed ID: 20551286 Adipose Tissue Recruitment of Leukocytes Current Opinion in Lipidology. Jun, 2010 | Pubmed ID: 20410821 Mouse Models of the Metabolic Syndrome Disease Models & Mechanisms. Mar-Apr, 2010 | Pubmed ID: 20212084 Nitro-fatty Acids Reduce Atherosclerosis in Apolipoprotein E-deficient Mice Arteriosclerosis, Thrombosis, and Vascular Biology. May, 2010 | Pubmed ID: 20167658 The Role of Chemokines in Recruitment of Immune Cells to the Artery Wall and Adipose Tissue Vascular Pharmacology. Jan-Feb, 2010 | Pubmed ID: 20026286 Dietary Fish Oil Exerts Hypolipidemic Effects in Lean and Insulin Sensitizing Effects in Obese LDLR-/- Mice The Journal of Nutrition. Dec, 2009 | Pubmed ID: 19864403 Defective Phagocytosis of Apoptotic Cells by Macrophages in Atherosclerotic Lesions of Ob/ob Mice and Reversal by a Fish Oil Diet Circulation Research. Nov, 2009 | Pubmed ID: 19834009 Inhibition of Long-chain Acyl Coenzyme A Synthetases During Fatty Acid Loading Induces Lipotoxicity in Macrophages Arteriosclerosis, Thrombosis, and Vascular Biology. Nov, 2009 | Pubmed ID: 19679826 Loss of Ovarian Function in the VCD Mouse-model of Menopause Leads to Insulin Resistance and a Rapid Progression into the Metabolic Syndrome American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. Sep, 2009 | Pubmed ID: 19439618 Impact of Increased Adipose Tissue Mass on Inflammation, Insulin Resistance, and Dyslipidemia Current Diabetes Reports. Feb, 2009 | Pubmed ID: 19192421 Lipid and Phospholipid Profiling of Biological Samples Using MALDI Fourier Transform Mass Spectrometry Lipids. Apr, 2009 | Pubmed ID: 19005715 Macrophage Infiltration into Adipose Tissue: Initiation, Propagation and Remodeling Future Lipidology. 2008 | Pubmed ID: 18978945 Palmitate Impairs and Eicosapentaenoate Restores Insulin Secretion Through Regulation of SREBP-1c in Pancreatic Islets Diabetes. Sep, 2008 | Pubmed ID: 18458149 Cyclin-dependent Kinase Inhibitor, P21WAF1/CIP1, is Involved in Adipocyte Differentiation and Hypertrophy, Linking to Obesity, and Insulin Resistance The Journal of Biological Chemistry. Jul, 2008 | Pubmed ID: 18445590 Central Nervous System Neuropeptide Y Signaling Modulates VLDL Triglyceride Secretion Diabetes. Jun, 2008 | Pubmed ID: 18332095 Atherosclerotic Lesion Formation and Triglyceride Storage in Obese Apolipoprotein AI-deficient Mice The Journal of Nutritional Biochemistry. Oct, 2008 | Pubmed ID: 18280133 The Role of Macrophage Leptin Receptor in Aortic Root Lesion Formation American Journal of Physiology. Endocrinology and Metabolism. Mar, 2008 | Pubmed ID: 18182468 Macrophage-derived Apolipoprotein E Ameliorates Dyslipidemia and Atherosclerosis in Obese Apolipoprotein E-deficient Mice American Journal of Physiology. Endocrinology and Metabolism. Feb, 2008 | Pubmed ID: 18029445 Crucial Role of a Long-chain Fatty Acid Elongase, Elovl6, in Obesity-induced Insulin Resistance Nature Medicine. Oct, 2007 | Pubmed ID: 17906635 Carbenoxolone Treatment Attenuates Symptoms of Metabolic Syndrome and Atherogenesis in Obese, Hyperlipidemic Mice American Journal of Physiology. Endocrinology and Metabolism. Dec, 2007 | Pubmed ID: 17878220 Leptin Requires Canonical Migratory Signaling Pathways for Induction of Monocyte and Macrophage Chemotaxis American Journal of Physiology. Cell Physiology. Nov, 2007 | Pubmed ID: 17728393 Fish Oil Increases Cholesterol Storage in White Adipose Tissue with Concomitant Decreases in Inflammation, Hepatic Steatosis, and Atherosclerosis in Mice The Journal of Nutrition. Jul, 2007 | Pubmed ID: 17585030 Direct Effect of Cholesterol on Insulin Secretion: a Novel Mechanism for Pancreatic Beta-cell Dysfunction Diabetes. Sep, 2007 | Pubmed ID: 17575085 Obesity Potentiates Development of Fatty Liver and Insulin Resistance, but Not Atherosclerosis, in High-fat Diet-fed Agouti LDLR-deficient Mice American Journal of Physiology. Endocrinology and Metabolism. Aug, 2007 | Pubmed ID: 17566116 Obesity Causes Very Low Density Lipoprotein Clearance Defects in Low-density Lipoprotein Receptor-deficient Mice The Journal of Nutritional Biochemistry. Nov, 2007 | Pubmed ID: 17418556 Diet-induced Increases in Adiposity, but Not Plasma Lipids, Promote Macrophage Infiltration into White Adipose Tissue Diabetes. Mar, 2007 | Pubmed ID: 17327423 Effects of Vitamin E on Oxidative Stress and Atherosclerosis in an Obese Hyperlipidemic Mouse Model The Journal of Nutritional Biochemistry. Feb, 2007 | Pubmed ID: 16781857 Deletion of the Gene Encoding the Ubiquitously Expressed Glucose-6-phosphatase Catalytic Subunit-related Protein (UGRP)/glucose-6-phosphatase Catalytic Subunit-beta Results in Lowered Plasma Cholesterol and Elevated Glucagon The Journal of Biological Chemistry. Dec, 2006 | Pubmed ID: 17023421 Granuphilin is Activated by SREBP-1c and Involved in Impaired Insulin Secretion in Diabetic Mice Cell Metabolism. Aug, 2006 | Pubmed ID: 16890542 The Role of Lipolysis in Mediating the Proinflammatory Effects of Very Low Density Lipoproteins in Mouse Peritoneal Macrophages Journal of Lipid Research. Jul, 2006 | Pubmed ID: 16639077 Quantitation and Cellular Localization of 11beta-HSD1 Expression in Murine Thymus The Journal of Steroid Biochemistry and Molecular Biology. May, 2006 | Pubmed ID: 16621520 Intracellular Trafficking of Recycling Apolipoprotein E in Chinese Hamster Ovary Cells Journal of Lipid Research. Jun, 2006 | Pubmed ID: 16534141 TFE3 Transcriptionally Activates Hepatic IRS-2, Participates in Insulin Signaling and Ameliorates Diabetes Nature Medicine. Jan, 2006 | Pubmed ID: 16327801 Plasminogen Activator Inhibitor-1 Modulates Adipocyte Differentiation American Journal of Physiology. Endocrinology and Metabolism. Jan, 2006 | Pubmed ID: 16144810 Plasma Insulin Levels Predict Atherosclerotic Lesion Burden in Obese Hyperlipidemic Mice Atherosclerosis. May, 2006 | Pubmed ID: 16102772 Physiological Relevance of Apolipoprotein E Recycling: Studies in Primary Mouse Hepatocytes Metabolism: Clinical and Experimental. Oct, 2005 | Pubmed ID: 16154429 Persistence of High Density Lipoprotein Particles in Obese Mice Lacking Apolipoprotein A-I Journal of Lipid Research. Sep, 2005 | Pubmed ID: 15995171 Recombinant Leptin Promotes Atherosclerosis and Thrombosis in Apolipoprotein E-deficient Mice Arteriosclerosis, Thrombosis, and Vascular Biology. Aug, 2005 | Pubmed ID: 15947243 Reduced ABCA1-mediated Cholesterol Efflux and Accelerated Atherosclerosis in Apolipoprotein E-deficient Mice Lacking Macrophage-derived ACAT1 Circulation. May, 2005 | Pubmed ID: 15851589 The Recycling of Apolipoprotein E in Macrophages: Influence of HDL and Apolipoprotein A-I Journal of Lipid Research. Jul, 2005 | Pubmed ID: 15805547 Macrophage Apolipoprotein A-I Expression Protects Against Atherosclerosis in ApoE-deficient Mice and Up-regulates ABC Transporters Molecular Therapy : the Journal of the American Society of Gene Therapy. Oct, 2003 | Pubmed ID: 14529830 Cross-talk Between Peroxisome Proliferator-activated Receptor (PPAR) Alpha and Liver X Receptor (LXR) in Nutritional Regulation of Fatty Acid Metabolism. I. PPARs Suppress Sterol Regulatory Element Binding Protein-1c Promoter Through Inhibition of LXR Signaling Molecular Endocrinology (Baltimore, Md.). Jul, 2003 | Pubmed ID: 12730331 Hepatocyte-derived ApoE is More Effective Than Non-hepatocyte-derived ApoE in Remnant Lipoprotein Clearance The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12551940 The Recycling of Apolipoprotein E in Primary Cultures of Mouse Hepatocytes. Evidence for a Physiologic Connection to High Density Lipoprotein Metabolism The Journal of Biological Chemistry. Mar, 2003 | Pubmed ID: 12524433 Physiological Expression of Macrophage ApoE in the Artery Wall Reduces Atherosclerosis in Severely Hyperlipidemic Mice Journal of Lipid Research. Oct, 2002 | Pubmed ID: 12364544 Transcriptional Activities of Nuclear SREBP-1a, -1c, and -2 to Different Target Promoters of Lipogenic and Cholesterogenic Genes Journal of Lipid Research. Aug, 2002 | Pubmed ID: 12177166 Cloning and Characterization of a Mammalian Fatty Acyl-CoA Elongase As a Lipogenic Enzyme Regulated by SREBPs Journal of Lipid Research. Jun, 2002 | Pubmed ID: 12032166 Absence of Sterol Regulatory Element-binding Protein-1 (SREBP-1) Ameliorates Fatty Livers but Not Obesity or Insulin Resistance in Lep(ob)/Lep(ob) Mice The Journal of Biological Chemistry. May, 2002 | Pubmed ID: 11923308 Dual Regulation of Mouse Delta(5)- and Delta(6)-desaturase Gene Expression by SREBP-1 and PPARalpha Journal of Lipid Research. Jan, 2002 | Pubmed ID: 11792729 Isolamento de tecido adiposo de células imunes Jeb S. Orr1, Arion J. Kennedy1, Alyssa H. Hasty1 1Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine JoVE 50707 Immunology and Infection
Isolamento de tecido adiposo de células imunes Jeb S. Orr1, Arion J. Kennedy1, Alyssa H. Hasty1 1Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine JoVE 50707 Immunology and Infection