Alyssa N. Coyne Brain Science Institute Johns Hopkins University School of Medicine Biography Publications Institution JoVE Articles Alyssa N. Coyne has not added a biography. If you are Alyssa N. Coyne and would like to personalize this page please email our Author Liaison for assistance. Publications Nuclear Accumulation of CHMP7 Initiates Nuclear Pore Complex Injury and Subsequent TDP-43 Dysfunction in Sporadic and Familial ALS Science Translational Medicine. 07, 2021 | Pubmed ID: 34321318 The ESCRT-III Protein VPS4, but Not CHMP4B or CHMP2B, is Pathologically Increased in Familial and Sporadic ALS Neuronal Nuclei Acta Neuropathologica Communications. 07, 2021 | Pubmed ID: 34281622 UPF1 Reduces C9orf72 HRE-induced Neurotoxicity in the Absence of Nonsense-mediated Decay Dysfunction Cell Reports. Mar, 2021 | Pubmed ID: 33789100 Nuclear Lamina Invaginations Are Not a Pathological Feature of C9orf72 ALS/FTD Acta Neuropathologica Communications. 03, 2021 | Pubmed ID: 33741069 GC Repeat RNA Initiates a POM121-Mediated Reduction in Specific Nucleoporins in C9orf72 ALS/FTD Neuron. 09, 2020 | Pubmed ID: 32673563 CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X As a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation Neuron. 12, 2019 | Pubmed ID: 31587919 Drosophila Models of Amyotrophic Lateral Sclerosis with Defects in RNA Metabolism Brain Research. 08, 2018 | Pubmed ID: 29752901 Nuclei Isolation and Super-Resolution Structured Illumination Microscopy for Examining Nucleoporin Alterations in Human Neurodegeneration Alyssa N. Coyne1,2, Jeffrey D. Rothstein1,2 1Brain Science Institute, Johns Hopkins University School of Medicine, 2Department of Neurology, Johns Hopkins University School of Medicine JoVE 62789 Neuroscience
Nuclei Isolation and Super-Resolution Structured Illumination Microscopy for Examining Nucleoporin Alterations in Human Neurodegeneration Alyssa N. Coyne1,2, Jeffrey D. Rothstein1,2 1Brain Science Institute, Johns Hopkins University School of Medicine, 2Department of Neurology, Johns Hopkins University School of Medicine JoVE 62789 Neuroscience
