quantified-assessment-infant-s-gross-motor-abilities-using

Quantified Assessment of Infant's Gross Motor Abilities Using a Multisensor Wearable

Developing objective and quantitative methods of early gross motor assessment is essential to better understand neurodevelopment and to support early ...

University Hospital

Infants' spontaneous and voluntary movements mirror developmental integrity of brain networks since they require coordinated activation of multiple sites in the central nervous system. Accordingly, early detection of infants with atypical motor development holds promise for recognizing those infants who are at risk for a wide range of neurodevelopmental disorders (e.g., cerebral palsy, autism spectrum disorders). Previously, novel wearable technology has shown promise for offering efficient, scalable and automated methods for movement assessment in adults. Here, we describe the development of an infant wearable, a multi-sensor smart jumpsuit that allows mobile accelerometer and gyroscope data collection during movements. Using this suit, we first recorded play sessions of 22 typically developing infants of approximately 7 months of age. These data were manually annotated for infant posture and movement based on video recordings of the sessions, and using a novel annotation scheme specifically designed to assess the overall movement pattern of infants in the given age group. A machine learning algorithm, based on deep convolutional neural networks (CNNs) was then trained for automatic detection of posture and movement classes using the data and annotations. Our experiments show that the setup can be used for quantitative tracking of infant movement activities with a human equivalent accuracy, i.e., it meets the human inter-rater agreement levels in infant posture and movement classification. We also quantify the ambiguity of human observers in analyzing infant movements, and propose a method for utilizing this uncertainty for performance improvements in training of the automated classifier. Comparison of different sensor configurations also shows that four-limb recording leads to the best performance in posture and movement classification.

Automatic Posture and Movement Tracking of Infants with Wearable Movement Sensors.

Early neurodevelopmental care needs better, effective and objective solutions for assessing infants' motor abilities. Novel wearable technology opens possibilities for characterizing spontaneous movement behavior. This work seeks to construct and validate a generalizable, scalable, and effective method to measure infants' spontaneous motor abilities across all motor milestones from lying supine to fluent walking.

Intelligent wearable allows out-of-the-lab tracking of developing motor abilities in infants.

Early neurodevelopmental care and research are in urgent need of practical methods for quantitative assessment of early motor development. Here, performance of a wearable system in early motor assessment was validated and compared to developmental tracking of physical growth charts.

Charting infants' motor development at home using a wearable system: validation and comparison to physical growth charts.

Familial risk for developmental dyslexia can compromise auditory and speech processing and subsequent language and literacy development. According to the phonological deficit theory, supporting phonological development during the sensitive infancy period could prevent or ameliorate future dyslexic symptoms. Music is an established method for supporting auditory and speech processing and even language and literacy, but no previous studies have investigated its benefits for infants at risk for developmental language and reading disorders. We pseudo-randomized N∼150 infants at risk for dyslexia to vocal or instrumental music listening interventions at 0-6 months, or to a no-intervention control group. Music listening was used as an easy-to-administer, cost-effective intervention in early infancy. Mismatch responses (MMRs) elicited by speech-sound changes were recorded with electroencephalogram (EEG) before (at birth) and after (at 6 months) the intervention and at a 28 months follow-up. We expected particularly the vocal intervention to promote phonological development, evidenced by enhanced speech-sound MMRs and their fast maturation. We found enhanced positive MMR amplitudes in the vocal music listening intervention group after but not prior to the intervention. Other music activities reported by parents did not differ between the three groups, indicating that the group effects were attributable to the intervention. The results speak for the use of vocal music in early infancy to support speech processing and subsequent language development in infants at developmental risk. RESEARCH HIGHLIGHTS: Dyslexia-risk infants were pseudo-randomly assigned to a vocal or instrumental music listening intervention at home from birth to 6 months of age. Neural mismatch responses (MMRs) to speech-sound changes were enhanced in the vocal music intervention group after but not prior to the intervention. Even passive vocal music listening in early infancy can support phonological development known to be deficient in dyslexia-risk.

Article	Year
Automatic Posture and Movement Tracking of Infants with Wearable Movement Sensors. Scientific reports\| PubMed ID: 31932616	2020
Intelligent wearable allows out-of-the-lab tracking of developing motor abilities in infants. Communications medicine\| PubMed ID: 35721830	2022
Charting infants' motor development at home using a wearable system: validation and comparison to physical growth charts. EBioMedicine\| PubMed ID: 37137181	2023
Beneficial effects of a music listening intervention on neural speech processing in 0-28-month-old children at risk for dyslexia. Developmental science\| PubMed ID: 37350469	2023

Anastasia Gallen

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