Anne-Christine Bay-Jensen Nordic Bioscience Biography Publications Institution JoVE Articles Anne-Christine Bay-Jensen has not added a biography. If you are Anne-Christine Bay-Jensen and would like to personalize this page please email our Author Liaison for assistance. Publications Biochemical Markers in Osteoarthritis with Lessons Learned from Osteoporosis Clinical and Experimental Rheumatology. Sep-Oct, 2019 | Pubmed ID: 31621570 Associations Between Biomarkers of Bone and Cartilage Turnover, Gender, Pain Categories and Radiographic Severity in Knee Osteoarthritis Arthritis Research & Therapy. Sep, 2019 | Pubmed ID: 31481084 Serological Assessment of the Quality of Wound Healing Processes in Crohn's Disease Journal of Gastrointestinal and Liver Diseases : JGLD. Jun, 2019 | Pubmed ID: 31204415 Osteoarthritis Phenotypes and Novel Therapeutic Targets Biochemical Pharmacology. Jul, 2019 | Pubmed ID: 30831073 Association of Metabolites Reflecting Type III and VI Collagen Formation with Modified Rodnan Skin Score in Systemic Sclerosis - a Cross-sectional Study Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. Jun, 2019 | Pubmed ID: 30821519 GPDPLQ-A Type II Collagen Neo-Epitope Biomarker of Osteoclast- and Inflammation-Derived Cartilage Degradation in Vitro Scientific Reports. Feb, 2019 | Pubmed ID: 30816326 Metabolites of C-reactive Protein and Vimentin Are Associated with Disease Activity of Axial Spondyloarthritis Clinical and Experimental Rheumatology. May-Jun, 2019 | Pubmed ID: 30767876 Serological Biomarker Profiles of Rapidly Progressive Osteoarthritis in Tanezumab-treated Patients Osteoarthritis and Cartilage. Mar, 2019 | Pubmed ID: 30576794 Osteoarthritis Year in Review 2018: Biomarkers (biochemical Markers) Osteoarthritis and Cartilage. Mar, 2019 | Pubmed ID: 30552966 Molecular Taxonomy of Osteoarthritis for Patient Stratification, Disease Management and Drug Development: Biochemical Markers Associated with Emerging Clinical Phenotypes and Molecular Endotypes Current Opinion in Rheumatology. 01, 2019 | Pubmed ID: 30461544 The VICM Biomarker is Released from Activated Macrophages and Inhibited by Anti-GM-CSFRα-mAb Treatment in Rheumatoid Arthritis Patients Clinical and Experimental Rheumatology. Jan-Feb, 2019 | Pubmed ID: 30418117 Tofacitinib and TPCA-1 Exert Chondroprotective Effects on Extracellular Matrix Turnover in Bovine Articular Cartilage Ex Vivo Biochemical Pharmacology. Jul, 2019 | Pubmed ID: 30059674 Bone and Soft Tissue Turnover in Relation to All-cause Mortality in Postmenopausal Women The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. Jun, 2019 | Pubmed ID: 30010805 Protein Biomarkers Associated with Pain Mechanisms in Osteoarthritis Journal of Proteomics. 01, 2019 | Pubmed ID: 29704569 Changes of Patient-reported Outcomes and Protein Fingerprint Biomarkers After Exercise Therapy for Axial Spondyloarthritis Clinical Rheumatology. Jan, 2019 | Pubmed ID: 28856518 Serum Biomarkers of Collagen Turnover As Potential Diagnostic Tools in Diffuse Systemic Sclerosis: A Cross-sectional Study PloS One. 2018 | Pubmed ID: 30507931 A Novel High Sensitivity Type II Collagen Blood-Based Biomarker, PRO-C2, for Assessment of Cartilage Formation International Journal of Molecular Sciences. Nov, 2018 | Pubmed ID: 30404167 Type IV Collagen Metabolism is Associated with Disease Activity, Radiographic Progression and Response to Tocilizumab in Rheumatoid Arthritis Clinical and Experimental Rheumatology. Sep-Oct, 2018 | Pubmed ID: 29745884 Aggrecanase Degradation of Type III Collagen is Associated with Clinical Knee Pain Clinical Biochemistry. Aug, 2018 | Pubmed ID: 29702061 Increased Remodelling of Interstitial Collagens and Basement Membrane is Suppressed by Treatment in Patients with Rheumatoid Arthritis: Serological Evaluation of a One-year Prospective Study of 149 Japanese Patients Clinical and Experimental Rheumatology. May-Jun, 2018 | Pubmed ID: 29465351 IL-6 Receptor Inhibition Modulates Type III Collagen and C-reactive Protein Degradation in Rheumatoid Arthritis Patients with an Inadequate Response to Anti-tumour Necrosis Factor Therapy: Analysis of Connective Tissue Turnover in the Tocilizumab RADIATE Study Clinical and Experimental Rheumatology. Jul-Aug, 2018 | Pubmed ID: 29465346 Identification of Pain Categories Associated with Change in Pain in Patients Receiving Placebo: Data from Two Phase 3 Randomized Clinical Trials in Symptomatic Knee Osteoarthritis BMC Musculoskeletal Disorders. 01, 2018 | Pubmed ID: 29343266 Blockade of GM-CSF Pathway Induced Sustained Suppression of Myeloid and T Cell Activities in Rheumatoid Arthritis Rheumatology (Oxford, England). 01, 2018 | Pubmed ID: 29069507 Biochemical Marker Discovery, Testing and Evaluation for Facilitating OA Drug Discovery and Development Drug Discovery Today. 02, 2018 | Pubmed ID: 29038075 Suppression of Active, but Not Total MMP-3, is Associated with Treatment Response in a Phase III Clinical Study of Rheumatoid Arthritis Clinical and Experimental Rheumatology. Jan-Feb, 2018 | Pubmed ID: 28850021 Soluble Biochemical Markers of Osteoarthritis: Are We Close to Using Them in Clinical Practice? Best Practice & Research. Clinical Rheumatology. 10, 2017 | Pubmed ID: 30509415 Sprifermin (rhFGF18) Modulates Extracellular Matrix Turnover in Cartilage Explants Ex Vivo Journal of Translational Medicine. Dec, 2017 | Pubmed ID: 29233174 Ulcerative Colitis, Crohn's Disease, and Irritable Bowel Syndrome Have Different Profiles of Extracellular Matrix Turnover, Which Also Reflects Disease Activity in Crohn's Disease PloS One. 2017 | Pubmed ID: 29028807 Excessive Matrix Metalloprotease-mediated Degradation of Interstitial Tissue (type I Collagen) Independently Predicts Short-term Survival in an Observational Study of Postmenopausal Women Diagnosed with Cancer Oncotarget. Aug, 2017 | Pubmed ID: 28881747 Unique Insight into Microenvironmental Changes in Colorectal Cancer: Assessment of Matrix Metalloprotease-mediated Molecular Changes in Human Colorectal Tumor Tissue and Corresponding Non-neoplastic Adjacent Tissue Oncology Letters. May, 2017 | Pubmed ID: 28529592 Biomarker of Extracellular Matrix Remodelling C1M and Proinflammatory Cytokine Interleukin 6 Are Related to Synovitis and Pain in End-stage Knee Osteoarthritis Patients Pain. 07, 2017 | Pubmed ID: 28333699 Nidogen-1 Degraded by Cathepsin S Can Be Quantified in Serum and is Associated with Non-Small Cell Lung Cancer Neoplasia (New York, N.Y.). 04, 2017 | Pubmed ID: 28282545 Type I and III Collagen Turnover is Increased in Axial Spondyloarthritis and Psoriatic Arthritis. Associations with Disease Activity and Diagnostic Capacity Clinical and Experimental Rheumatology. Jul-Aug, 2017 | Pubmed ID: 28240584 Remodeling of the Tumor Microenvironment Predicts Increased Risk of Cancer in Postmenopausal Women: The Prospective Epidemiologic Risk Factor (PERF I) Study Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. 09, 2016 | Pubmed ID: 27411352 Chondrocyte Activity is Increased in Psoriatic Arthritis and Axial Spondyloarthritis Arthritis Research & Therapy. 06, 2016 | Pubmed ID: 27306080 Intercritical Circulating Levels of Neo-epitopes Reflecting Matrixmetalloprotease-driven Degradation As Markers of Gout and Frequent Gout Attacks Rheumatology (Oxford, England). 09, 2016 | Pubmed ID: 27256715 Neo-Epitopes--Fragments of Cartilage and Connective Tissue Degradation in Early Rheumatoid Arthritis and Unclassified Arthritis PloS One. 2016 | Pubmed ID: 27019199 Synovitis Biomarkers: Ex Vivo Characterization of Three Biomarkers for Identification of Inflammatory Osteoarthritis Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 2015 | Pubmed ID: 26863055 Serum Cartilage Oligomeric Matrix Protein and Development of Radiographic and Painful Knee Osteoarthritis. A Community-based Cohort of Middle-aged Women Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 2015 | Pubmed ID: 26848781 Fragments of Citrullinated and MMP-degraded Vimentin and MMP-degraded Type III Collagen Are Novel Serological Biomarkers to Differentiate Crohn's Disease from Ulcerative Colitis Journal of Crohn's & Colitis. Oct, 2015 | Pubmed ID: 26188349 Clinical Drug Development Using Dynamic Biomarkers to Enable Personalized Health Care in COPD Chest. Jul, 2015 | Pubmed ID: 25856563 Novel Insights into the Function and Dynamics of Extracellular Matrix in Liver Fibrosis American Journal of Physiology. Gastrointestinal and Liver Physiology. May, 2015 | Pubmed ID: 25767261 Cartilage Turnover Reflected by Metabolic Processing of Type II Collagen: a Novel Marker of Anabolic Function in Chondrocytes International Journal of Molecular Sciences. Oct, 2014 | Pubmed ID: 25329619 Serum Biomarkers Reflecting Specific Tumor Tissue Remodeling Processes Are Valuable Diagnostic Tools for Lung Cancer Cancer Medicine. Oct, 2014 | Pubmed ID: 25044252 The Active Form of MMP-3 is a Marker of Synovial Inflammation and Cartilage Turnover in Inflammatory Joint Diseases BMC Musculoskeletal Disorders. Mar, 2014 | Pubmed ID: 24641725 Rheumatoid Arthritis: a Case for Personalized Health Care? Arthritis Care & Research. Sep, 2014 | Pubmed ID: 24470057 Extracellular Matrix Specific Protein Fingerprints Measured in Serum Can Separate Pancreatic Cancer Patients from Healthy Controls BMC Cancer. Nov, 2013 | Pubmed ID: 24261855 Quantification of "end Products" of Tissue Destruction in Inflammation May Reflect Convergence of Cytokine and Signaling Pathways -- Implications for Modern Clinical Chemistry Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. Aug, 2013 | Pubmed ID: 23721060 Extracellular Matrix Remodeling: the Common Denominator in Connective Tissue Diseases. Possibilities for Evaluation and Current Understanding of the Matrix As More Than a Passive Architecture, but a Key Player in Tissue Failure Assay and Drug Development Technologies. Mar, 2013 | Pubmed ID: 23046407 Investigation of Chondrocyte Hypertrophy and Cartilage Calcification in a Full-depth Articular Cartilage Explants Model Rheumatology International. Feb, 2013 | Pubmed ID: 22453523 Future Detection and Monitoring of Diabetes May Entail Analysis of Both β-cell Function and Volume: How Markers of β-cell Loss May Assist Journal of Translational Medicine. Oct, 2012 | Pubmed ID: 23110768 The Inhibitory Effect of Salmon Calcitonin on Tri-iodothyronine Induction of Early Hypertrophy in Articular Cartilage PloS One. 2012 | Pubmed ID: 22768225 Characterization of an Ex Vivo Femoral Head Model Assessed by Markers of Bone and Cartilage Turnover Cartilage. Jul, 2011 | Pubmed ID: 26069585 Diagnosis of Osteoarthritis by Cartilage Surface Smoothness Quantified Automatically from Knee MRI Cartilage. Jan, 2011 | Pubmed ID: 26069569 Molecular Serum and Urine Marker Repertoire Supporting Clinical Research on Joint Diseases Best Practice & Research. Clinical Rheumatology. Dec, 2011 | Pubmed ID: 22265266 Glucocorticoids Exert Context-dependent Effects on Cells of the Joint in Vitro Steroids. Dec, 2011 | Pubmed ID: 21855558 Biochemical Markers of Ongoing Joint Damage in Rheumatoid Arthritis--current and Future Applications, Limitations and Opportunities Arthritis Research & Therapy. Apr, 2011 | Pubmed ID: 21539724 Measurement of Matrix Metalloproteinase 9-mediated Collagen Type III Degradation Fragment As a Marker of Skin Fibrosis BMC Dermatology. Mar, 2011 | Pubmed ID: 21447148 Enzyme-linked Immunosorbent Assay (ELISAs) for Metalloproteinase Derived Type II Collagen Neoepitope, CIIM--increased Serum CIIM in Subjects with Severe Radiographic Osteoarthritis Clinical Biochemistry. Apr, 2011 | Pubmed ID: 21223960 Oral Salmon Calcitonin--pharmacology in Osteoporosis Expert Opinion on Biological Therapy. Nov, 2010 | Pubmed ID: 20932224 Novel Combinations of Post-Translational Modification (PTM) Neo-epitopes Provide Tissue-specific Biochemical Markers--are They the Cause or the Consequence of the Disease? Clinical Biochemistry. Jul, 2010 | Pubmed ID: 20381482 Investigation of the Direct Effects of Salmon Calcitonin on Human Osteoarthritic Chondrocytes BMC Musculoskeletal Disorders. Apr, 2010 | Pubmed ID: 20367884 Procollagen Type I N-terminal Propeptide (PINP) is a Marker for Fibrogenesis in Bile Duct Ligation-induced Fibrosis in Rats Fibrogenesis & Tissue Repair. Apr, 2010 | Pubmed ID: 20359335 Serum Markers of Liver Fibrosis: Combining the BIPED Classification and the Neo-epitope Approach in the Development of New Biomarkers Disease Markers. 2010 | Pubmed ID: 20164543 Application of Biochemical Markers in Development of Drugs for Treatment of Osteoarthritis Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. Feb, 2010 | Pubmed ID: 20085489 Aggrecanase- and Matrix Metalloproteinase-mediated Aggrecan Degradation is Associated with Different Molecular Characteristics of Aggrecan and Separated in Time Ex Vivo Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. May, 2010 | Pubmed ID: 20039789 Which Elements Are Involved in Reversible and Irreversible Cartilage Degradation in Osteoarthritis? Rheumatology International. Feb, 2010 | Pubmed ID: 19816688 Biochemical Markers of Joint Tissue Turnover Assay and Drug Development Technologies. Feb, 2010 | Pubmed ID: 19715454 Suppression of MMP Activity in Bovine Cartilage Explants Cultures Has Little if Any Effect on the Release of Aggrecanase-derived Aggrecan Fragments BMC Research Notes. Dec, 2009 | Pubmed ID: 20021645 The Disease Modifying Osteoarthritis Drug (DMOAD): Is It in the Horizon? Pharmacological Research. Jul, 2008 | Pubmed ID: 18590824 牛膝剥離植物における軟骨改造のEx Vivo組織培養モデル Christian S. Thudium*1, Amalie Engstrom*1,2, Solveig S. Groen1, Morten A. Karsdal1, Anne-Christine Bay-Jensen1 1Nordic Bioscience, 2Department of Biomedical Sciences, University of Copenhagen JoVE 59467 Biology
牛膝剥離植物における軟骨改造のEx Vivo組織培養モデル Christian S. Thudium*1, Amalie Engstrom*1,2, Solveig S. Groen1, Morten A. Karsdal1, Anne-Christine Bay-Jensen1 1Nordic Bioscience, 2Department of Biomedical Sciences, University of Copenhagen JoVE 59467 Biology