Atsushi Kumanogoh Department of Respiratory Medicine and Clinical Immunology Osaka University Graduate School of Medicine Biography Publications Institution JoVE Articles Atsushi Kumanogoh has not added a biography. If you are Atsushi Kumanogoh and would like to personalize this page please email our Author Liaison for assistance. Publications Severe Myocarditis with Slight Lymphocytic Infiltration After Nivolumab Treatment Lung Cancer (Amsterdam, Netherlands). Feb, 2020 | Pubmed ID: 31848027 Metagenome-wide Association Study of Gut Microbiome Revealed Novel Aetiology of Rheumatoid Arthritis in the Japanese Population Annals of the Rheumatic Diseases. Jan, 2020 | Pubmed ID: 31699813 Monitoring Antibody Binding to T Cells in a Pembrolizumab-treated Patient with Lung Adenocarcinoma on Hemodialysis Thoracic Cancer. Nov, 2019 | Pubmed ID: 31520515 The Outcomes of Induction Chemoradiotherapy Followed by Surgery for Clinical T3-4 Non-Small Cell Lung Cancer Technology in Cancer Research & Treatment. 01, 2019 | Pubmed ID: 31455166 Immune Adjuvant Therapy Using Bacillus Calmette-Guérin Cell Wall Skeleton (BCG-CWS) in Advanced Malignancies: A Phase 1 Study of Safety and Immunogenicity Assessments Medicine. Aug, 2019 | Pubmed ID: 31415377 The Therapeutic Efficacy of Intravenous Immunoglobulin in Anti-neutrophilic Cytoplasmic Antibody-associated Vasculitis: a Meta-analysis Rheumatology (Oxford, England). Aug, 2019 | Pubmed ID: 31377800 A Lung Abscess Caused by Secondary Syphilis - the Utility of Polymerase Chain Reaction Techniques in Transbronchial Biopsy: a Case Report BMC Infectious Diseases. Jul, 2019 | Pubmed ID: 31288744 Response To: 'Blood Plasma Versus Serum: Which is Right for Sampling Circulating Membrane Microvesicles in Human Subjects?' by Liu Annals of the Rheumatic Diseases. May, 2019 | Pubmed ID: 31097418 Correction To: Drug Tolerability and Reasons for Discontinuation of Seven Biologics in 4466 Treatment Courses of Rheumatoid Arthritis-the ANSWER Cohort Study Arthritis Research & Therapy. May, 2019 | Pubmed ID: 31060597 Unique Case of Pseudoprogression Manifesting As Lung Cavitation After Pembrolizumab Treatment Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. 05, 2019 | Pubmed ID: 31027746 Drug Tolerability and Reasons for Discontinuation of Seven Biologics in 4466 Treatment Courses of Rheumatoid Arthritis-the ANSWER Cohort Study Arthritis Research & Therapy. 04, 2019 | Pubmed ID: 30971306 Anti-receptor Activator of Nuclear Factor κB Ligand Antibody Treatment Increases Osteoclastogenesis-promoting IL-8 in Patients with Rheumatoid Arthritis International Immunology. 04, 2019 | Pubmed ID: 30753461 SEMA4A Promotes Eosinophil Survival and Contributes to Eosinophil-mediated Allergic Diseases Allergology International : Official Journal of the Japanese Society of Allergology. Apr, 2019 | Pubmed ID: 30342889 Long-term Outcomes of Advanced Thymoma in Patients Undergoing Preoperative Chemotherapy or Chemoradiotherapy Followed by Surgery: a 20-year Experience Interactive Cardiovascular and Thoracic Surgery. 03, 2019 | Pubmed ID: 30256943 Eosinophil-derived Neurotoxin Enhances Airway Remodeling in Eosinophilic Chronic Rhinosinusitis and Correlates with Disease Severity International Immunology. 02, 2019 | Pubmed ID: 30239772 Eukaryotic Translation Initiation Factor 3 Subunit C is Associated with Acquired Resistance to Erlotinib in Non-small Cell Lung Cancer Oncotarget. Dec, 2018 | Pubmed ID: 30680067 Semaphorin 7A Promotes EGFR-TKI Resistance in EGFR Mutant Lung Adenocarcinoma Cells JCI Insight. 12, 2018 | Pubmed ID: 30568033 Extremely Strong Infiltration of WT1-specific CTLs into Mouse Tumor by the Combination Vaccine with WT1-specific CTL and Helper Peptides Oncotarget. Nov, 2018 | Pubmed ID: 30542516 Integration of Genetics and MiRNA-target Gene Network Identified Disease Biology Implicated in Tissue Specificity Nucleic Acids Research. 12, 2018 | Pubmed ID: 30407537 Clinical Implications of Monitoring Nivolumab Immunokinetics in Non-small Cell Lung Cancer Patients JCI Insight. 10, 2018 | Pubmed ID: 30282824 The Direct Oblique Method: A New Gold Standard for Bronchoscopic Navigation That is Superior to Automatic Methods Journal of Bronchology & Interventional Pulmonology. Oct, 2018 | Pubmed ID: 29901530 Semaphorin 6D Reverse Signaling Controls Macrophage Lipid Metabolism and Anti-inflammatory Polarization Nature Immunology. 06, 2018 | Pubmed ID: 29777213 Cerebrospinal Fluid Mitochondrial DNA in Neuromyelitis Optica Spectrum Disorder Journal of Neuroinflammation. Apr, 2018 | Pubmed ID: 29703264 Lysosomal Protein Lamtor1 Controls Innate Immune Responses Via Nuclear Translocation of Transcription Factor EB Journal of Immunology (Baltimore, Md. : 1950). 06, 2018 | Pubmed ID: 29686050 Double Deletion of Tetraspanins CD9 and CD81 in Mice Leads to a Syndrome Resembling Accelerated Aging Scientific Reports. 03, 2018 | Pubmed ID: 29572511 Beneficial Effects of Fingolimod in MS Patients with High Serum Sema4A Levels PloS One. 2018 | Pubmed ID: 29518148 Combination Gemcitabine and WT1 Peptide Vaccination Improves Progression-Free Survival in Advanced Pancreatic Ductal Adenocarcinoma: A Phase II Randomized Study Cancer Immunology Research. Jan, 2018 | Pubmed ID: 29358173 WT1 Peptide-based Immunotherapy for Advanced Thymic Epithelial Malignancies International Journal of Cancer. 06, 2018 | Pubmed ID: 29322496 Clinical Response to PD-1 Blockade Correlates with a Sub-fraction of Peripheral Central Memory CD4+ T Cells in Patients with Malignant Melanoma International Immunology. 02, 2018 | Pubmed ID: 29294043 Minimal Neonatal Transfer of Certolizumab Pegol in a Japanese Patient with Rheumatoid Arthritis Annals of the Rheumatic Diseases. 09, 2018 | Pubmed ID: 28939633 Wilms Tumour 1 Peptide Vaccine As a Cure-oriented Post-chemotherapy Strategy for Patients with Acute Myeloid Leukaemia at High Risk of Relapse British Journal of Haematology. 07, 2018 | Pubmed ID: 28542830 Quantitative Pulmonary Blood Flow Measurement Using O-HO PET with and Without Tissue Fraction Correction: a Comparison Study EJNMMI Research. Dec, 2017 | Pubmed ID: 29274016 Febuxostat Ameliorates Secondary Progressive Experimental Autoimmune Encephalomyelitis by Restoring Mitochondrial Energy Production in a GOT2-dependent Manner PloS One. 2017 | Pubmed ID: 29107957 The Activated Conformation of Integrin β is a Novel Multiple Myeloma-specific Target for CAR T Cell Therapy Nature Medicine. Dec, 2017 | Pubmed ID: 29106400 Wilms' Tumor Gene 1 (WT1) Peptide Vaccine Therapy for Hematological Malignancies: From CTL Epitope Identification to Recent Progress in Clinical Studies Including a Cure-Oriented Strategy Oncology Research and Treatment. 2017 | Pubmed ID: 29041012 Gallbladder-derived Surfactant Protein D Regulates Gut Commensal Bacteria for Maintaining Intestinal Homeostasis Proceedings of the National Academy of Sciences of the United States of America. 09, 2017 | Pubmed ID: 28878025 Lamtor1 Is Critically Required for CD4 T Cell Proliferation and Regulatory T Cell Suppressive Function Journal of Immunology (Baltimore, Md. : 1950). 09, 2017 | Pubmed ID: 28768723 Carboplatin Plus Weekly Nanoparticle Albumin-bound Paclitaxel in Elderly Patients with Previously Untreated Advanced Squamous Non-small-cell Lung Cancer Selected Based on Mini Nutritional Assessment Short-form Scores: a Multicenter Phase 2 Study Cancer Chemotherapy and Pharmacology. Sep, 2017 | Pubmed ID: 28688052 Trastuzumab Emtansine Suppresses the Growth of HER2-positive Small-cell Lung Cancer in Preclinical Models Biochemical and Biophysical Research Communications. 07, 2017 | Pubmed ID: 28526406 Interleukin-17A Promotes Lung Tumor Progression Through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. 08, 2017 | Pubmed ID: 28483607 Semaphorin 4D Inhibits Neutrophil Activation and is Involved in the Pathogenesis of Neutrophil-mediated Autoimmune Vasculitis Annals of the Rheumatic Diseases. Aug, 2017 | Pubmed ID: 28416516 Mouse Model of Epstein-Barr Virus LMP1- and LMP2A-driven Germinal Center B-cell Lymphoproliferative Disease Proceedings of the National Academy of Sciences of the United States of America. 05, 2017 | Pubmed ID: 28351978 Classification of Idiopathic Interstitial Pneumonias Using Anti-myxovirus Resistance-protein 1 Autoantibody Scientific Reports. 02, 2017 | Pubmed ID: 28230086 Rapid Intracranial Response to Osimertinib, Without Radiotherapy, in Nonsmall Cell Lung Cancer Patients Harboring the EGFR T790M Mutation: Two Case Reports Medicine. Feb, 2017 | Pubmed ID: 28178168 Characterizing Semaphorin-Mediated Immune Responses Using an Antigen-Presentation Assay Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 27787865 Syndecan-4 As a Biomarker to Predict Clinical Outcome for Glioblastoma Multiforme Treated with WT1 Peptide Vaccine Future Science OA. Dec, 2016 | Pubmed ID: 28116121 The Role of Sema4A in Angiogenesis, Immune Responses, Carcinogenesis, and Retinal Systems Cell Adhesion & Migration. 11, 2016 | Pubmed ID: 27736304 Clarifying the Biological Significance of the CHK2 K373E Somatic Mutation Discovered in The Cancer Genome Atlas Database FEBS Letters. Dec, 2016 | Pubmed ID: 27716909 The Proportion of Regulatory T Cells in Patients with Rheumatoid Arthritis: A Meta-Analysis PloS One. 2016 | Pubmed ID: 27622457 Sialylation Converts Arthritogenic IgG into Inhibitors of Collagen-induced Arthritis Nature Communications. Apr, 2016 | Pubmed ID: 27046227 Glycosylation Status of CD43 Protein Is Associated with Resistance of Leukemia Cells to CTL-Mediated Cytolysis PloS One. 2016 | Pubmed ID: 27011118 An Immunocompetent Mouse Model for MLL/AF9 Leukemia Reveals the Potential of Spontaneous Cytotoxic T-Cell Response to an Antigen Expressed in Leukemia Cells PloS One. 2015 | Pubmed ID: 26658107 MTOR Complex Signaling Through the SEMA4A-Plexin B2 Axis Is Required for Optimal Activation and Differentiation of CD8+ T Cells Journal of Immunology (Baltimore, Md. : 1950). Aug, 2015 | Pubmed ID: 26116513 Leucine-Rich Repeat Kinase 1 Regulates Autophagy Through Turning On TBC1D2-Dependent Rab7 Inactivation Molecular and Cellular Biology. Sep, 2015 | Pubmed ID: 26100023 Interleukin-6/interleukin-21 Signaling Axis is Critical in the Pathogenesis of Pulmonary Arterial Hypertension Proceedings of the National Academy of Sciences of the United States of America. May, 2015 | Pubmed ID: 25941359 Dapsone Hypersensitivity Syndrome-related Lung Injury Without Eosinophilia in the Bronchoalveolar Lavage Fluid Internal Medicine (Tokyo, Japan). 2015 | Pubmed ID: 25832951 Semaphorin 4D Contributes to Rheumatoid Arthritis by Inducing Inflammatory Cytokine Production: Pathogenic and Therapeutic Implications Arthritis & Rheumatology (Hoboken, N.J.). Jun, 2015 | Pubmed ID: 25707877 Favorable Response to Trastuzumab Plus Irinotecan Combination Therapy in Two Patients with HER2-positive Relapsed Small-cell Lung Cancer Lung Cancer (Amsterdam, Netherlands). Mar, 2015 | Pubmed ID: 25601188 CD16+CD56+ Cells Are a Potential Culprit for Hematuria in IgA Nephropathy Clinical and Experimental Nephrology. Apr, 2015 | Pubmed ID: 24798970 Expansion of Range of Joint Motion Following Treatment of Systemic Sclerosis with Tocilizumab Modern Rheumatology. Jan, 2015 | Pubmed ID: 24533556 Development of Microscopic Polyangiitis-related Pulmonary Fibrosis in a Patient with Autoimmune Pulmonary Alveolar Proteinosis BMC Pulmonary Medicine. Nov, 2014 | Pubmed ID: 25366193 Germline Variants in the SEMA4A Gene Predispose to Familial Colorectal Cancer Type X Nature Communications. Oct, 2014 | Pubmed ID: 25307848 Vaccination Strategies to Improve Outcome of Hematopoietic Stem Cell Transplant in Leukemia Patients: Early Evidence and Future Prospects Expert Review of Hematology. Oct, 2014 | Pubmed ID: 25186852 A Retrospective Study of Prognostic Factors in Patients with Interstitial Pneumonia Receiving Long-term Oxygen Therapy Lung. Oct, 2014 | Pubmed ID: 25056241 Comprehensive Exploration of Autoantibody in Behçet's Disease: a Novel Autoantibody to Claudin-1, an Essential Protein for Tight Junctions, is Identified Joint, Bone, Spine : Revue Du Rhumatisme. Dec, 2014 | Pubmed ID: 24792642 Efficacy and Safety of Pirfenidone for Idiopathic Pulmonary Fibrosis Patient Preference and Adherence. 2014 | Pubmed ID: 24711695 Sema4A Inhibits the Therapeutic Effect of IFN-β in EAE Journal of Neuroimmunology. Mar, 2014 | Pubmed ID: 24439904 Tocilizumab for the Treatment of Patients with Refractory Takayasu Arteritis International Heart Journal. 2013 | Pubmed ID: 24309452 DNA Damage in Rheumatoid Arthritis: an Age-dependent Increase in the Lipid Peroxidation-derived DNA Adduct, Heptanone-etheno-2'-deoxycytidine Autoimmune Diseases. 2013 | Pubmed ID: 24222845 Statins Decrease Lung Inflammation in Mice by Upregulating Tetraspanin CD9 in Macrophages PloS One. 2013 | Pubmed ID: 24040034 Overcoming Chemoresistance of Small-cell Lung Cancer Through Stepwise HER2-targeted Antibody-dependent Cell-mediated Cytotoxicity and VEGF-targeted Antiangiogenesis Scientific Reports. 2013 | Pubmed ID: 24036898 Molecular Mechanism Underlying the Antiproliferative Effect of Suppressor of Cytokine Signaling-1 in Non-small-cell Lung Cancer Cells Cancer Science. Nov, 2013 | Pubmed ID: 23962256 Interleukin-16 Promotes Cardiac Fibrosis and Myocardial Stiffening in Heart Failure with Preserved Ejection Fraction PloS One. 2013 | Pubmed ID: 23894370 Calretinin Mediates Apoptosis in Small Cell Lung Cancer Cells Expressing Tetraspanin CD9 FEBS Open Bio. 2013 | Pubmed ID: 23772398 Drug-induced Thrombotic Thrombocytopenic Purpura Successfully Treated with Recombinant Human Soluble Thrombomodulin Internal Medicine (Tokyo, Japan). 2013 | Pubmed ID: 23676600 HLA-DPB1*05: 01-restricted WT1332-specific TCR-transduced CD4+ T Lymphocytes Display a Helper Activity for WT1-specific CTL Induction and a Cytotoxicity Against Leukemia Cells Journal of Immunotherapy (Hagerstown, Md. : 1997). Apr, 2013 | Pubmed ID: 23502763 A Point Mutation in Semaphorin 4A Associates with Defective Endosomal Sorting and Causes Retinal Degeneration Nature Communications. 2013 | Pubmed ID: 23360997 Echinoderm Microtubule-associated Protein-like 4 (EML4)-anaplastic Lymphoma Kinase (ALK) Rearrangement in Congenital Pulmonary Airway Malformation Clinical Lung Cancer. Jul, 2013 | Pubmed ID: 23357247 Functional Human Th17 Clones with WT1-specific Helper Activity Cancer Immunology, Immunotherapy : CII. Apr, 2013 | Pubmed ID: 23275045 Deletion of Tetraspanin CD9 Diminishes Lymphangiogenesis in Vivo and in Vitro The Journal of Biological Chemistry. Jan, 2013 | Pubmed ID: 23223239 Semaphorins in Bone Development, Homeostasis, and Disease Seminars in Cell & Developmental Biology. Mar, 2013 | Pubmed ID: 23022498 Recognition of a Natural WT1 Epitope by a Modified WT1 Peptide-specific T-cell Receptor Anticancer Research. Dec, 2012 | Pubmed ID: 23225417 Pathological Role of Interleukin-6 in Psoriatic Arthritis Arthritis. 2012 | Pubmed ID: 23133751 Adiponectin: a Novel Link Between Adipocytes and COPD Vitamins and Hormones. 2012 | Pubmed ID: 23017725 Suppression of Metastases of Small Cell Lung Cancer Cells in Mice by a Peptidic CXCR4 Inhibitor TF14016 FEBS Letters. Oct, 2012 | Pubmed ID: 22992418 Inhibitory Roles of Signal Transducer and Activator of Transcription 3 in Antitumor Immunity During Carcinogen-induced Lung Tumorigenesis Cancer Research. Jun, 2012 | Pubmed ID: 22659452 Tetraspanin CD151 Protects Against Pulmonary Fibrosis by Maintaining Epithelial Integrity American Journal of Respiratory and Critical Care Medicine. Jul, 2012 | Pubmed ID: 22592804 Elevation of Sema4A Implicates Th Cell Skewing and the Efficacy of IFN-β Therapy in Multiple Sclerosis Journal of Immunology (Baltimore, Md. : 1950). May, 2012 | Pubmed ID: 22491253 Endosomal Sorting by Semaphorin 4A in Retinal Pigment Epithelium Supports Photoreceptor Survival Genes & Development. Apr, 2012 | Pubmed ID: 22465952 HER2 As Therapeutic Target for Overcoming ATP-binding Cassette Transporter-mediated Chemoresistance in Small Cell Lung Cancer Molecular Cancer Therapeutics. Apr, 2012 | Pubmed ID: 22389470 Biased Usage of T Cell Receptor β-chain Variable Region Genes of Wilms' Tumor Gene (WT1)-specific CD8+ T Cells in Patients with Solid Tumors and Healthy Donors Cancer Science. Mar, 2012 | Pubmed ID: 22126448 Early [18F]fluorodeoxyglucose Positron Emission Tomography at Two Days of Gefitinib Treatment Predicts Clinical Outcome in Patients with Adenocarcinoma of the Lung Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2012 | Pubmed ID: 22019513 Psoriatic Arthritis in Two Patients with an Inadequate Response to Treatment with Tocilizumab Joint, Bone, Spine : Revue Du Rhumatisme. Jan, 2012 | Pubmed ID: 21962389 A Case of Behçet's Disease Treated with a Humanized Anti-interleukin-6 Receptor Antibody, Tocilizumab Modern Rheumatology. Apr, 2012 | Pubmed ID: 21748365 The Lactic Acid Bacterium Pediococcus Acidilactici Suppresses Autoimmune Encephalomyelitis by Inducing IL-10-producing Regulatory T Cells PloS One. 2011 | Pubmed ID: 22110705 The Role of Immune Semaphorins in Multiple Sclerosis FEBS Letters. Dec, 2011 | Pubmed ID: 21420960 Semaphorins Guide the Entry of Dendritic Cells into the Lymphatics by Activating Myosin II Nature Immunology. Jul, 2010 | Pubmed ID: 20512151 Anti-aquaporin-4 Antibody Induces Astrocytic Cytotoxicity in the Absence of CNS Antigen-specific T Cells Biochemical and Biophysical Research Communications. Mar, 2010 | Pubmed ID: 20188706 Roles of Sema4D-plexin-B1 Interactions in the Central Nervous System for Pathogenesis of Experimental Autoimmune Encephalomyelitis Journal of Immunology (Baltimore, Md. : 1950). Feb, 2010 | Pubmed ID: 20038643 Neuromyelitis Optica: Passive Transfer to Rats by Human Immunoglobulin Biochemical and Biophysical Research Communications. Sep, 2009 | Pubmed ID: 19545538 Astrocytic Necrosis is Induced by Anti-aquaporin-4 Antibody-positive Serum Neuroreport. Mar, 2009 | Pubmed ID: 19297740 Involvement of Sema4A in the Progression of Experimental Autoimmune Myocarditis FEBS Letters. Nov, 2008 | Pubmed ID: 18977352 Edaravone, a Free Radical Scavenger, Ameliorates Experimental Autoimmune Encephalomyelitis Neuroscience Letters. Aug, 2008 | Pubmed ID: 18579300 Semaphorin-4A, an Activator for T-cell-mediated Immunity, Suppresses Angiogenesis Via Plexin-D1 The EMBO Journal. Mar, 2007 | Pubmed ID: 17318185 FARP2 Triggers Signals for Sema3A-mediated Axonal Repulsion Nature Neuroscience. Dec, 2005 | Pubmed ID: 16286926 Loss of Dopaminergic Neurons by the Induction of Inducible Nitric Oxide Synthase and Cyclooxygenase-2 Via CD 40: Relevance to Parkinson's Disease Journal of Neuroscience Research. Sep, 2005 | Pubmed ID: 16041799 Guidance of Myocardial Patterning in Cardiac Development by Sema6D Reverse Signalling Nature Cell Biology. Dec, 2004 | Pubmed ID: 15543137 Induction of Cyclooxygenase-2 in Reactive Glial Cells by the CD40 Pathway: Relevance to Amyotrophic Lateral Sclerosis Journal of Neurochemistry. Oct, 2004 | Pubmed ID: 15447673 Dual Roles of Sema6D in Cardiac Morphogenesis Through Region-specific Association of Its Receptor, Plexin-A1, with Off-track and Vascular Endothelial Growth Factor Receptor Type 2 Genes & Development. Feb, 2004 | Pubmed ID: 14977921 Überwachung von PD-1-Blocking-Antikörpern, die an T-Zellen gebunden sind, die aus einem Tropfen peripheren Blutsfetts abgeleitet wurden Yujiro Naito1, Akio Osa1, Kentaro Masuhiro1, Takashi Hirai1, Shohei Koyama1, Atsushi Kumanogoh1 1Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine JoVE 60608 Medicine
Überwachung von PD-1-Blocking-Antikörpern, die an T-Zellen gebunden sind, die aus einem Tropfen peripheren Blutsfetts abgeleitet wurden Yujiro Naito1, Akio Osa1, Kentaro Masuhiro1, Takashi Hirai1, Shohei Koyama1, Atsushi Kumanogoh1 1Department of Respiratory Medicine and Clinical Immunology, Osaka University Graduate School of Medicine JoVE 60608 Medicine