David A. Wassarman

Publications

• Mutations in Complex I of the Mitochondrial Electron-Transport Chain Sensitize the Fruit Fly () to Ether and Non-Ether Volatile Anesthetics
  International Journal of Molecular Sciences. Jan, 2023  |   Pubmed ID: 36768163
• Lissencephaly-1 Mutations Enhance Traumatic Brain Injury Outcomes in Drosophila
  Genetics. Jan, 2023  |   Pubmed ID: 36683334
• Anesthetic Preconditioning of Traumatic Brain Injury Is Ineffective in a Drosophila Model of Obesity
  The Journal of Pharmacology and Experimental Therapeutics. Jun, 2022  |   Pubmed ID: 35347062
• Beta-blockers Reduce Intestinal Permeability and Early Mortality Following Traumatic Brain Injury in
  MicroPublication Biology. 2021  |   Pubmed ID: 34723144
• Ketogenic Diet Reduces Early Mortality Following Traumatic Brain Injury in Drosophila Via the PPARγ Ortholog Eip75B
  PloS One. 2021  |   Pubmed ID: 34699541
• Effects of Blunt Force Injuries in Third-instar Larvae Persist Through Metamorphosis and Reduce Adult Lifespan
  MicroPublication Biology. 2021  |   Pubmed ID: 34278243
• Survival Following Traumatic Brain Injury in Is Increased by Heterozygosity for a Mutation of the NF-κB Innate Immune Response Transcription Factor Relish
  Genetics. Dec, 2020  |   Pubmed ID: 33109529
• Interactions Among Genetic Background, Anesthetic Agent, and Oxygen Concentration Shape Blunt Traumatic Brain Injury Outcomes in
  International Journal of Molecular Sciences. Sep, 2020  |   Pubmed ID: 32967238
• Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity
  Anesthesiology. Oct, 2020  |   Pubmed ID: 32773682
• Loss of the Antimicrobial Peptide Metchnikowin Protects Against Traumatic Brain Injury Outcomes in
  G3 (Bethesda, Md.). Sep, 2020  |   Pubmed ID: 32631949
• Ageing and Genetic Background Influence Anaesthetic Effects in a D. melanogaster Model of Blunt Trauma with Brain Injury
  British Journal of Anaesthesia. Jul, 2020  |   Pubmed ID: 32466842
• Anesthetics Influence Mortality in a Drosophila Model of Blunt Trauma With Traumatic Brain Injury
  Anesthesia and Analgesia. Jun, 2018  |   Pubmed ID: 29596093
• Genetic Variability Affects Absolute and Relative Potencies and Kinetics of the Anesthetics Isoflurane and Sevoflurane in Drosophila Melanogaster
  Scientific Reports. 02, 2018  |   Pubmed ID: 29402974
• A Pharmacological Screen for Compounds That Rescue the Developmental Lethality of a Drosophila ATM Mutant
  PloS One. 2018  |   Pubmed ID: 29338042
• Age and Diet Affect Genetically Separable Secondary Injuries That Cause Acute Mortality Following Traumatic Brain Injury in Drosophila
  G3 (Bethesda, Md.). Dec, 2016  |   Pubmed ID: 27754853
• The Gut Reaction to Traumatic Brain Injury
  Fly. 2015  |   Pubmed ID: 26291482
• Death Following Traumatic Brain Injury in Drosophila is Associated with Intestinal Barrier Dysfunction
  ELife. 2015  |   Pubmed ID: 25742603
• A Drosophila Model of Closed Head Traumatic Brain Injury
  Proceedings of the National Academy of Sciences of the United States of America. Oct, 2013  |   Pubmed ID: 24127584
• The Innate Immune Response Transcription Factor Relish is Necessary for Neurodegeneration in a Drosophila Model of Ataxia-telangiectasia
  Genetics. May, 2013  |   Pubmed ID: 23502677
• The Drosophila Translational Control Element (TCE) is Required for High-level Transcription of Many Genes That Are Specifically Expressed in Testes
  PloS One. 2012  |   Pubmed ID: 22984601
• Drosophila Innate Immune Response Pathways Moonlight in Neurodegeneration
  Fly. Jul-Sep, 2012  |   Pubmed ID: 22864563
• ATM Kinase Inhibition in Glial Cells Activates the Innate Immune Response and Causes Neurodegeneration in Drosophila
  Proceedings of the National Academy of Sciences of the United States of America. Mar, 2012  |   Pubmed ID: 22355133
• The Effect of ATM Knockdown on Ionizing Radiation-induced Neuronal Cell Cycle Reentry in Drosophila
  Cell Cycle (Georgetown, Tex.). Jul, 2010  |   Pubmed ID: 20581464
• Ubiquilin Modifies TDP-43 Toxicity in a Drosophila Model of Amyotrophic Lateral Sclerosis (ALS)
  The Journal of Biological Chemistry. Apr, 2010  |   Pubmed ID: 20154090
• Promoting Developmental Transcription
  Development (Cambridge, England). Jan, 2010  |   Pubmed ID: 20023156
• Control of Alternative Splicing by Signal-dependent Degradation of Splicing-regulatory Proteins
  The Journal of Biological Chemistry. Apr, 2009  |   Pubmed ID: 19218244
• A DNA Damage Signal Activates and Derepresses Exon Inclusion in Drosophila TAF1 Alternative Splicing
  RNA (New York, N.Y.). Aug, 2008  |   Pubmed ID: 18596254
• Mutations in String/CDC25 Inhibit Cell Cycle Re-entry and Neurodegeneration in a Drosophila Model of Ataxia Telangiectasia
  Genes & Development. May, 2008  |   Pubmed ID: 18408079
• Cyclic Disulfides As Functional Mimics of the Histone Deacetylase Inhibitor FK-228
  Tetrahedron Letters. Jun, 2007  |   Pubmed ID: 18575573
• Nucleolar Colocalization of TAF1 and Testis-specific TAFs During Drosophila Spermatogenesis
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Oct, 2007  |   Pubmed ID: 17823958
• ATM and ATR Pathways Signal Alternative Splicing of Drosophila TAF1 Pre-mRNA in Response to DNA Damage
  Molecular and Cellular Biology. Dec, 2006  |   Pubmed ID: 17030624
• DNA Binding Properties of TAF1 Isoforms with Two AT-hooks
  The Journal of Biological Chemistry. Oct, 2006  |   Pubmed ID: 16893881
• TAF1 Activates Transcription by Phosphorylation of Serine 33 in Histone H2B
  Science (New York, N.Y.). May, 2004  |   Pubmed ID: 15143281
• The SIN3 Deacetylase Complex Represses Genes Encoding Mitochondrial Proteins: Implications for the Regulation of Energy Metabolism
  The Journal of Biological Chemistry. Sep, 2003  |   Pubmed ID: 12865422
• The SIN3/RPD3 Deacetylase Complex is Essential for G(2) Phase Cell Cycle Progression and Regulation of SMRTER Corepressor Levels
  Molecular and Cellular Biology. Jul, 2002  |   Pubmed ID: 12077326
• Localizing Transcription Factors on Chromatin by Immunofluorescence
  Methods (San Diego, Calif.). Jan, 2002  |   Pubmed ID: 12054899