Dunja Bruder Immune Regulation Group Helmholtz Centre for Infection Research Biography Publications Institution JoVE Articles Dunja Bruder has not added a biography. If you are Dunja Bruder and would like to personalize this page please email our Author Liaison for assistance. Publications Eosinophilic Pulmonary Vasculitis As a Manifestation of the Hyperinflammatory Phase of COVID-19 The Journal of Allergy and Clinical Immunology. 01, 2021 | Pubmed ID: 33139059 Resolved Influenza A Virus Infection Has Extended Effects on Lung Homeostasis and Attenuates Allergic Airway Inflammation in a Mouse Model Microorganisms. Nov, 2020 | Pubmed ID: 33260910 NMP4: a Nuclear Driver of Innate Inflammatory Responses During Influenza A Virus Infection Cellular & Molecular Immunology. Dec, 2020 | Pubmed ID: 32747686 Topological Data Analysis to Model the Shape of Immune Responses During Co-infections Communications in Nonlinear Science & Numerical Simulation. Jun, 2020 | Pubmed ID: 32288422 ADAP Promotes Degranulation and Migration of NK Cells Primed During Infection in Mice Frontiers in Immunology. 2019 | Pubmed ID: 32038647 Mucosal CD8+ T Cell Responses Induced by an MCMV Based Vaccine Vector Confer Protection Against Influenza Challenge PLoS Pathogens. 09, 2019 | Pubmed ID: 31525249 Neutralization of Pro-inflammatory Cytokines During Secondary Infection Post Influenza A Virus Infection Frontiers in Immunology. 2019 | Pubmed ID: 31474978 The STING Activator C-di-AMP Exerts Superior Adjuvant Properties Than the Formulation Poly(I:C)/CpG After Subcutaneous Vaccination with Soluble Protein Antigen or DEC-205-mediated Antigen Targeting to Dendritic Cells Vaccine. 08, 2019 | Pubmed ID: 31320219 Essential Role of IκB for in Vivo CD4 T-cell Activation, Proliferation, and Th1-cell Differentiation During Listeria Monocytogenes Infection in Mice European Journal of Immunology. 09, 2019 | Pubmed ID: 31049948 Gamma Secretase Dependent Release of the CD44 Cytoplasmic Tail Upregulates IFI16 in Cd44-/- Tumor Cells, MEFs and Macrophages PloS One. 2018 | Pubmed ID: 30540779 Activates Human Mucosal-Associated Invariant T Cells Frontiers in Microbiology. 2018 | Pubmed ID: 30410474 Presence of Infected Gr-1CD11bCD11c Monocytic Myeloid Derived Suppressor Cells Subverts T Cell Response and Is Associated With Impaired Dendritic Cell Function in -Infected Mice Frontiers in Immunology. 2018 | Pubmed ID: 30386330 Hemodialysis-related Changes in Phenotypical Features of Monocytes Scientific Reports. 09, 2018 | Pubmed ID: 30228352 Respiratory Carriage is Associated with Broad Phenotypic Alterations of Peripheral CD4⁺CD25⁺ T Cells and Differentially Affects Immune Responses to Secondary Non-Infectious and Infectious Stimuli in Mice International Journal of Molecular Sciences. Sep, 2018 | Pubmed ID: 30200513 Proteomic Definition of Human Mucosal-associated Invariant T cells Determines Their Unique Molecular Effector Phenotype European Journal of Immunology. 08, 2018 | Pubmed ID: 29749611 Respiratory Influenza A Virus Infection Triggers Local and Systemic Natural Killer Cell Activation Toll-Like Receptor 7 Frontiers in Immunology. 2018 | Pubmed ID: 29497422 Chronic Lung Inflammation Primes Humoral Immunity and Augments Antipneumococcal Resistance Scientific Reports. 07, 2017 | Pubmed ID: 28694492 IL-33: a Jack of All Trades in the Orchestration of Respiratory Antibacterial Immunity Cellular & Molecular Immunology. Jul, 2017 | Pubmed ID: 28690328 C-REL and IκB Govern Common and Independent Steps of Regulatory T Cell Development from Novel CD122-Expressing Pre-Precursors Journal of Immunology (Baltimore, Md. : 1950). 08, 2017 | Pubmed ID: 28652399 Targeted Antigen Delivery to Dendritic Cells Elicits Robust Antiviral T Cell-mediated Immunity in the Liver Scientific Reports. Mar, 2017 | Pubmed ID: 28266658 Soluble CD200 Correlates With Interleukin-6 Levels in Sera of COPD Patients: Potential Implication of the CD200/CD200R Axis in the Disease Course Lung. 02, 2017 | Pubmed ID: 27864635 Mechanism of Granuloma Formation in Sarcoidosis Current Opinion in Hematology. 01, 2017 | Pubmed ID: 27755127 ADAP Plays a Pivotal Role in CD4+ T Cell Activation but is Only Marginally Involved in CD8+ T Cell Activation, Differentiation, and Immunity to Pathogens Journal of Leukocyte Biology. 02, 2017 | Pubmed ID: 27605210 Hierarchical Effects of Pro-inflammatory Cytokines on the Post-influenza Susceptibility to Pneumococcal Coinfection Scientific Reports. 11, 2016 | Pubmed ID: 27872472 A Cell Culture-derived Whole Virus Influenza A Vaccine Based on Magnetic Sulfated Cellulose Particles Confers Protection in Mice Against Lethal Influenza A Virus Infection Vaccine. 12, 2016 | Pubmed ID: 27816372 Influenza A Virus Infection Predisposes Hosts to Secondary Infection with Different Streptococcus Pneumoniae Serotypes with Similar Outcome but Serotype-Specific Manifestation Infection and Immunity. Dec, 2016 | Pubmed ID: 27647871 Oseltamivir PK/PD Modeling and Simulation to Evaluate Treatment Strategies Against Influenza-Pneumococcus Coinfection Frontiers in Cellular and Infection Microbiology. 2016 | Pubmed ID: 27379214 Alveolar Type II Epithelial Cells Contribute to the Anti-Influenza A Virus Response in the Lung by Integrating Pathogen- and Microenvironment-Derived Signals MBio. May, 2016 | Pubmed ID: 27143386 ImmunoPET/MR Imaging Allows Specific Detection of Aspergillus Fumigatus Lung Infection in Vivo Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26787852 Modeling Influenza Virus Infection: A Roadmap for Influenza Research Viruses. Oct, 2015 | Pubmed ID: 26473911 Erratum To: Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease Lung. Dec, 2015 | Pubmed ID: 26459043 Morphological and Functional Alterations of Alveolar Macrophages in a Murine Model of Chronic Inflammatory Lung Disease Lung. Dec, 2015 | Pubmed ID: 26319657 First Genomic Analysis of Dendritic Cells from Lung and Draining Lymph Nodes in Murine Asthma International Journal of Genomics. 2015 | Pubmed ID: 25811019 Ly6C(high) Monocytes Control Cerebral Toxoplasmosis Journal of Immunology (Baltimore, Md. : 1950). Apr, 2015 | Pubmed ID: 25710908 Evidence for a Causal Link Between Adaptor Protein PDZK1 Downregulation and Na⁺/H⁺ Exchanger NHE3 Dysfunction in Human and Murine Colitis Pflugers Archiv : European Journal of Physiology. Aug, 2015 | Pubmed ID: 25271043 Attenuation of Immune-mediated Influenza Pneumonia by Targeting the Inducible Co-stimulator (ICOS) Molecule on T Cells PloS One. 2014 | Pubmed ID: 25029240 Interferon Regulatory Factor-1 Protects from Fatal Neurotropic Infection with Vesicular Stomatitis Virus by Specific Inhibition of Viral Replication in Neurons PLoS Pathogens. Mar, 2014 | Pubmed ID: 24675692 芯片对芯片分析标识作为直接目标基因的人类 T 细胞 Ectopically 表达 FOXP3 转录因子 IL-22。 BMC Genomics. Dec, 2012 | Pubmed ID: 23244505 TLR7 有助于快速进展,而不是整体致命结果的辅助肺炎球菌疾病后流感病毒感染。 Journal of Innate Immunity. Nov, 2012 | Pubmed ID: 23154432 白细胞介素-4 减轻肺上皮细胞介导抑制 T 细胞引发。 PloS One. 2012 | Pubmed ID: 23029313 CD8 + T 细胞响应肺泡自我抗原缺乏 CD25 表达和沉淀自身免疫的失败。 American Journal of Respiratory Cell and Molecular Biology. Dec, 2012 | Pubmed ID: 22984087 癌症、 慢性病毒性感染的治疗干预: 抗体介导的 PD-1/PD-L1 交互操作。 Reviews on Recent Clinical Trials. Feb, 2012 | Pubmed ID: 22023178 表达式 Qtl 在规管和帮助器 T 细胞株 BXD 家庭从揭示新细胞特异性基因、 基因-基因交互作用和自身免疫性疾病的候选基因。 BMC Genomics. 2011 | Pubmed ID: 22182475 病症肝细胞衰老监控限制肝癌发展。 Nature. Nov, 2011 | Pubmed ID: 22080947 规管 T 细胞在异基因干细胞移植。 Blood. Sep, 2011 | Pubmed ID: 21778340 辐射诱导 Pneumopathy 分子病理学的新见解。 Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Oct, 2011 | Pubmed ID: 21722981 CD4 + CD25 + Foxp3 + T 细胞监管控制 CD8 + T 细胞介导肺炎症缺一不可。 Journal of Immunology (Baltimore, Md. : 1950). Jun, 2011 | Pubmed ID: 21518973 抑制淋巴细胞贩运脑卒中后屏蔽有害 Neuroinflammation 对大脑。 Brain : a Journal of Neurology. Mar, 2011 | Pubmed ID: 21354973 CX3CR1 + 集落树突状细胞是与相关的浆细胞样树突状细胞的稳态的人口。 Proceedings of the National Academy of Sciences of the United States of America. Aug, 2010 | Pubmed ID: 20679228 新型记者鼠标显示本构和炎症干扰素 - β 体内的表达。 Journal of Immunology (Baltimore, Md. : 1950). Sep, 2009 | Pubmed ID: 19667093 频率和基因表达谱的规管在肾细胞癌中的 T 细胞。 Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine. 2009 | Pubmed ID: 19609102 宿主遗传背景强烈影响针对流感病毒感染。 PloS One. 2009 | Pubmed ID: 19293935 与链球菌肺炎期间流感病毒感染不由 TLR7 介导的淋巴细胞减少引起二重感染的敏感性增加。 PloS One. 2009 | Pubmed ID: 19290047 二型肺泡上皮细胞目前到 CD4(+) T 细胞抗原和诱导 Foxp3(+) 监管的 T 细胞。 American Journal of Respiratory and Critical Care Medicine. Mar, 2009 | Pubmed ID: 19096007 益生菌大肠杆菌 Nissle 1917 抑制漏肠的提高黏膜的完整性。 PloS One. 2007 | Pubmed ID: 18074031 慢性抗原刺激体内诱导抗原特异性 Foxp3 CD25 规管 T 细胞的不同的人口。 Journal of Immunology (Baltimore, Md. : 1950). Dec, 2007 | Pubmed ID: 18056346 类型二、 肺泡上皮细胞的 CD4 + T 细胞表型变化介导肺炎症。 Respiratory Research. 2007 | Pubmed ID: 17610738 肠上皮抗原诱导 CD4 + T 细胞与自身免疫性转基因小鼠模型中的规管表型。 Annals of the New York Academy of Sciences. Aug, 2006 | Pubmed ID: 17057222 免疫介导肠道炎症影响和抗原特异性 CD8 + T 细胞调节。 Gastroenterology. Aug, 2006 | Pubmed ID: 16890605 呼吸道病毒感染细胞的免疫功能和肺损伤。 Viral Immunology. 2006 | Pubmed ID: 16817757 幼稚的 CD4 + CD25 T 细胞中的 G 蛋白偶联受体 83 过度表达导致 Foxp3 + 监管 T 细胞体内诱导。 Journal of Immunology (Baltimore, Md. : 1950). Jul, 2006 | Pubmed ID: 16785516 肺上皮 NF 活化和 Stat1 CD8 + T 细胞抗原识别的响应信号。 Journal of Interferon & Cytokine Research : the Official Journal of the International Society for Interferon and Cytokine Research. May, 2006 | Pubmed ID: 16689660 多个 Synergizing 因素有助于对 Listeriolysin O.CD8 + T 细胞反应的强度 International Immunology. Jan, 2006 | Pubmed ID: 16291651 边缘的自身免疫: T 细胞刺激稳态树突状细胞可以防止自身免疫性糖尿病。 Diabetes. Dec, 2005 | Pubmed ID: 16306354 肠道免疫功能的大肠埃希氏大肠杆菌 NISSLE 1917: 安全承运人对治疗的分子。 FEMS Immunology and Medical Microbiology. Mar, 2005 | Pubmed ID: 15708311 淋巴样细胞亚群 B220 + 与鼻相关淋巴组织中的免疫调节功能的表征。 Journal of Immunology (Baltimore, Md. : 1950). Feb, 2005 | Pubmed ID: 15661888 CD4 T 淋巴细胞介导的肺部疾病: 稳态之间病理和耐受免疫反应。 American Journal of Respiratory and Critical Care Medicine. Dec, 2004 | Pubmed ID: 15306530 黏-1: 监管 T 细胞的表面标志。 European Journal of Immunology. Mar, 2004 | Pubmed ID: 14991591 纯化的DEC-205定向抗体与全长蛋白的化学偶联,用于在体外和体内靶向小鼠树突状细胞 Julia Volckmar1,2, Laura Knop1,2,3, Tatjana Hirsch1, Sarah Frentzel1,2, Christian Erck4, Marco van Ham4, Sabine Stegemann-Koniszewski*1,2,5, Dunja Bruder*1,2 1Immune Regulation Group, Helmholtz Centre for Infection Research, 2Infection Immunology Group, Institute of Medical Microbiology, Infection Prevention and Control, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 3Institute for Molecular and Clinical Immunology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 4Cellular Proteome Research, Helmholtz Centre for Infection Research, 5Experimental Pneumology, University Hospital of Pneumology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg JoVE 62018 Cancer Research 主要鼠Ⅱ型肺泡上皮细胞的功能及分子生物学研究的流式细胞仪分离 Marcus Gereke1,2, Andrea Autengruber1,2, Lothar Gröbe3, Andreas Jeron2, Dunja Bruder1,2, Sabine Stegemann-Koniszewski1 1Research Group Immune Regulation, Helmholtz Centre for Infection Research, 2Research Group Infection Immunology, Institute of Medical Microbiology, Otto-von-Guericke University, 3Department of Experimental Immunology, Helmholtz Centre for Infection Research JoVE 4322 Immunology and Infection
纯化的DEC-205定向抗体与全长蛋白的化学偶联,用于在体外和体内靶向小鼠树突状细胞 Julia Volckmar1,2, Laura Knop1,2,3, Tatjana Hirsch1, Sarah Frentzel1,2, Christian Erck4, Marco van Ham4, Sabine Stegemann-Koniszewski*1,2,5, Dunja Bruder*1,2 1Immune Regulation Group, Helmholtz Centre for Infection Research, 2Infection Immunology Group, Institute of Medical Microbiology, Infection Prevention and Control, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 3Institute for Molecular and Clinical Immunology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg, 4Cellular Proteome Research, Helmholtz Centre for Infection Research, 5Experimental Pneumology, University Hospital of Pneumology, Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke University Magdeburg JoVE 62018 Cancer Research
主要鼠Ⅱ型肺泡上皮细胞的功能及分子生物学研究的流式细胞仪分离 Marcus Gereke1,2, Andrea Autengruber1,2, Lothar Gröbe3, Andreas Jeron2, Dunja Bruder1,2, Sabine Stegemann-Koniszewski1 1Research Group Immune Regulation, Helmholtz Centre for Infection Research, 2Research Group Infection Immunology, Institute of Medical Microbiology, Otto-von-Guericke University, 3Department of Experimental Immunology, Helmholtz Centre for Infection Research JoVE 4322 Immunology and Infection