Eiji Shigetomi Department of Neuropharmacology, Faculty of Medicine University of Yamanashi Biography Publications Institution JoVE Articles Eiji Shigetomi has not added a biography. If you are Eiji Shigetomi and would like to personalize this page please email our Author Liaison for assistance. Publications Transient Astrocytic MGluR5 Expression Drives Synaptic Plasticity and Subsequent Chronic Pain in Mice The Journal of Experimental Medicine. 04, 2022 | Pubmed ID: 35319723 Effects of Fatty Acid Metabolites on Nocturia Scientific Reports. 02, 2022 | Pubmed ID: 35197540 Abnormal Ca Signals in Reactive Astrocytes As a Common Cause of Brain Diseases International Journal of Molecular Sciences. Dec, 2021 | Pubmed ID: 35008573 Adenosine A Receptor Down-regulates Metabotropic Glutamate Receptor 5 in Astrocytes During Postnatal Development Glia. 11, 2021 | Pubmed ID: 34339538 Transnasal Transplantation of Human Induced Pluripotent Stem Cell-derived Microglia to the Brain of Immunocompetent Mice Glia. 10, 2021 | Pubmed ID: 34309082 Different Effects of GsMTx4 on Nocturia Associated with the Circadian Clock and Piezo1 Expression in Mice Life Sciences. Aug, 2021 | Pubmed ID: 33930366 Reactive Astrocyte-driven Epileptogenesis is Induced by Microglia Initially Activated Following Status Epilepticus JCI Insight. 05, 2021 | Pubmed ID: 33830944 Author Correction: Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. Nov, 2019 | Pubmed ID: 31700120 Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. 07, 2019 | Pubmed ID: 31296902 Aberrant Calcium Signals in Reactive Astrocytes: A Key Process in Neurological Disorders International Journal of Molecular Sciences. Feb, 2019 | Pubmed ID: 30823575 The Time-dependent Variation of ATP Release in Mouse Primary-cultured Urothelial Cells is Regulated by the Clock Gene Neurourology and Urodynamics. 11, 2018 | Pubmed ID: 30106187 Anti-Depressant Fluoxetine Reveals Its Therapeutic Effect Via Astrocytes EBioMedicine. Jun, 2018 | Pubmed ID: 29887330 The Oscillation of Intracellular Ca Influx Associated with the Circadian Expression of Piezo1 and TRPV4 in the Bladder Urothelium Scientific Reports. 04, 2018 | Pubmed ID: 29632308 Aberrant Astrocyte Ca Signals "AxCa Signals" Exacerbate Pathological Alterations in an Alexander Disease Model Glia. 05, 2018 | Pubmed ID: 29383757 Role of Purinergic Receptor P2Y1 in Spatiotemporal Ca Dynamics in Astrocytes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 02, 2018 | Pubmed ID: 29305530 The Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT, Associated with the Expression Levels of the Clock Genes in Mouse Primary Cultured Urothelial Cells Neurourology and Urodynamics. 03, 2018 | Pubmed ID: 28881406 Author Correction: Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 11, 2017 | Pubmed ID: 29138397 Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence Neuron. Aug, 2017 | Pubmed ID: 28712653 Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 06, 2017 | Pubmed ID: 28642575 Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia Via P2Y Receptor Downregulation Cell Reports. 05, 2017 | Pubmed ID: 28494865 P2Y-deficiency Increases Micturition Frequency and Attenuates Sustained Contractility of the Urinary Bladder in Mice Scientific Reports. 04, 2017 | Pubmed ID: 28396595 Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa PloS One. 2017 | Pubmed ID: 28060940 The Clock Mutant Mouse is a Novel Experimental Model for Nocturia and Nocturnal Polyuria Neurourology and Urodynamics. Apr, 2017 | Pubmed ID: 27348079 Urothelial ATP Exocytosis: Regulation of Bladder Compliance in the Urine Storage Phase Scientific Reports. 07, 2016 | Pubmed ID: 27412485 Cortical Astrocytes Rewire Somatosensory Cortical Circuits for Peripheral Neuropathic Pain The Journal of Clinical Investigation. May, 2016 | Pubmed ID: 27064281 Probing the Complexities of Astrocyte Calcium Signaling Trends in Cell Biology. Apr, 2016 | Pubmed ID: 26896246 Müller Cell-mediated Neurite Outgrowth of the Retinal Ganglion Cells Via P2Y Receptor Signals Journal of Neurochemistry. Feb, 2016 | Pubmed ID: 26560804 Imagerie Calcique Microdomaines Dans Territoires Astrocyte Ensemble Et Endfeet Avec GCaMPs Exprimées à L'aide De Virus Adéno-associés The Journal of General Physiology. May, 2013 | Pubmed ID: 23589582 TRPA1 Chaînes Réglementer Les Astrocytes De Calcium De Repos Et De L'efficacité Synapse Inhibitrice Grâce GAT-3 Nature Neuroscience. Jan, 2012 | Pubmed ID: 22158513 Neuronaux Récepteurs P2X2 Sont Mobiles Capteurs ATP Qui Explorent La Membrane Plasmique Lorsqu'il Est Activé The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2011 | Pubmed ID: 22090499 [Règlement Synaptique Par Les Astrocytes] Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Oct, 2011 | Pubmed ID: 21986065 Chargement En Vrac De Colorants Indicateur De Calcium Pour étudier La Physiologie Astrocytes: Limitations Clés Et Améliorations à L'aide Cartes Morphologiques The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2011 | Pubmed ID: 21697385 Suivi Des Microdomaines Calcium Dans Les Astrocytes Avec Membrane Amélioration Ciblée Reporters GCaMP Neuron Glia Biology. Dec, 2010 | Pubmed ID: 21205365 Un Capteur Optique Génétiquement Ciblée Pour Surveiller Les Signaux De Calcium Dans Les Processus D'astrocytes Nature Neuroscience. Jun, 2010 | Pubmed ID: 20495558 Deux Formes De Calcium Dans Les Astrocytes Excitabilité Des Effets Différents Sur Des Récepteurs NMDA à Médiation Courants Entrants Lents Dans Les Neurones Pyramidaux The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2008 | Pubmed ID: 18579739 Suivi émetteur-gated Activation Du Canal P2X Cations in Vitro Et in Vivo Nature Methods. Jan, 2008 | Pubmed ID: 18084300 [Purinergiques Réglementaire Complexe Dans Les Synapses Du Cerveau] Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2007 | Pubmed ID: 17633523 Facilitation De La Libération Spontanée De Glycine Par Anoxie Potentialise Les Récepteurs De NMDA Actuel Dans Les Motoneurones Hypoglosse Du Rat The European Journal of Neuroscience. Mar, 2007 | Pubmed ID: 17408431 Bloqueur Résistant Présynaptiques Canaux Voltage-dépendants Ca2 + Qui Sous-tendent Le Glutamate Release En Souris Noyau Du Faisceau Solitaire Brain Research. Aug, 2006 | Pubmed ID: 16814754 Un Double Rôle Joué Par L'ATP Extracellulaire Dans Le Filtrage De La Fréquence Du Réseau Noyau Du Faisceau Solitaire Advances in Experimental Medicine and Biology. 2004 | Pubmed ID: 15602957 Potentiel D'action Indépendant De La Libération De Glutamate Par L'entrée De Ca2 + Par Le Biais De Récepteurs P2X Présynaptiques Suscite Postsynaptique Tir Dans Le Réseau Du Système Nerveux Autonome Du Tronc Cérébral The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2004 | Pubmed ID: 15044552 ATP Adénosine-médiation Et Signalisation Dans Le Système Nerveux Central : Récepteurs Purinergiques Synaptique : La Voie à L'ATP Jouer Son « Double Rôle » Journal of Pharmacological Sciences. Feb, 2004 | Pubmed ID: 14978346 Prime Augmente Dans Les Niveaux De Récepteurs P2X Dans Les Neurones D'efférente Vagale Rat Suite à Une Section Du Nerf Vague Brain Research. Jul, 2003 | Pubmed ID: 12788520 Analyse Des Mécanismes Moléculaires Contrôlant La Transmission Synaptique Par Patch-clamp, Enregistrement En Tranches Du Tronc Cérébral Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Apr, 2003 | Pubmed ID: 12777844 In vivo Imagerie calcique à grand champ et à deux photons d’une souris utilisant une grande fenêtre crânienne Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 Neuroscience Transplantation de microglies dérivées de cellules souches pluripotentes induites par l’homme dans le cerveau de souris immunocompétentes par voie transnasale non invasive Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 Neuroscience Mesure Proche membrane plasmique et mondiale dynamique du calcium intracellulaire dans les astrocytes Eiji Shigetomi1, Baljit S. Khakh1 1Departments of Physiology and Neurobiology, David Geffen School of Medicine, University of California, Los Angeles JoVE 1142 Biology
In vivo Imagerie calcique à grand champ et à deux photons d’une souris utilisant une grande fenêtre crânienne Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 Neuroscience
Transplantation de microglies dérivées de cellules souches pluripotentes induites par l’homme dans le cerveau de souris immunocompétentes par voie transnasale non invasive Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 Neuroscience
Mesure Proche membrane plasmique et mondiale dynamique du calcium intracellulaire dans les astrocytes Eiji Shigetomi1, Baljit S. Khakh1 1Departments of Physiology and Neurobiology, David Geffen School of Medicine, University of California, Los Angeles JoVE 1142 Biology