Eiji Shigetomi Department of Neuropharmacology, Faculty of Medicine University of Yamanashi Biography Publications Institution JoVE Articles Eiji Shigetomi has not added a biography. If you are Eiji Shigetomi and would like to personalize this page please email our Author Liaison for assistance. Publications Transient Astrocytic MGluR5 Expression Drives Synaptic Plasticity and Subsequent Chronic Pain in Mice The Journal of Experimental Medicine. 04, 2022 | Pubmed ID: 35319723 Effects of Fatty Acid Metabolites on Nocturia Scientific Reports. 02, 2022 | Pubmed ID: 35197540 Abnormal Ca Signals in Reactive Astrocytes As a Common Cause of Brain Diseases International Journal of Molecular Sciences. Dec, 2021 | Pubmed ID: 35008573 Adenosine A Receptor Down-regulates Metabotropic Glutamate Receptor 5 in Astrocytes During Postnatal Development Glia. 11, 2021 | Pubmed ID: 34339538 Transnasal Transplantation of Human Induced Pluripotent Stem Cell-derived Microglia to the Brain of Immunocompetent Mice Glia. 10, 2021 | Pubmed ID: 34309082 Different Effects of GsMTx4 on Nocturia Associated with the Circadian Clock and Piezo1 Expression in Mice Life Sciences. Aug, 2021 | Pubmed ID: 33930366 Reactive Astrocyte-driven Epileptogenesis is Induced by Microglia Initially Activated Following Status Epilepticus JCI Insight. 05, 2021 | Pubmed ID: 33830944 Author Correction: Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. Nov, 2019 | Pubmed ID: 31700120 Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. 07, 2019 | Pubmed ID: 31296902 Aberrant Calcium Signals in Reactive Astrocytes: A Key Process in Neurological Disorders International Journal of Molecular Sciences. Feb, 2019 | Pubmed ID: 30823575 The Time-dependent Variation of ATP Release in Mouse Primary-cultured Urothelial Cells is Regulated by the Clock Gene Neurourology and Urodynamics. 11, 2018 | Pubmed ID: 30106187 Anti-Depressant Fluoxetine Reveals Its Therapeutic Effect Via Astrocytes EBioMedicine. Jun, 2018 | Pubmed ID: 29887330 The Oscillation of Intracellular Ca Influx Associated with the Circadian Expression of Piezo1 and TRPV4 in the Bladder Urothelium Scientific Reports. 04, 2018 | Pubmed ID: 29632308 Aberrant Astrocyte Ca Signals "AxCa Signals" Exacerbate Pathological Alterations in an Alexander Disease Model Glia. 05, 2018 | Pubmed ID: 29383757 Role of Purinergic Receptor P2Y1 in Spatiotemporal Ca Dynamics in Astrocytes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 02, 2018 | Pubmed ID: 29305530 The Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT, Associated with the Expression Levels of the Clock Genes in Mouse Primary Cultured Urothelial Cells Neurourology and Urodynamics. 03, 2018 | Pubmed ID: 28881406 Author Correction: Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 11, 2017 | Pubmed ID: 29138397 Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence Neuron. Aug, 2017 | Pubmed ID: 28712653 Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 06, 2017 | Pubmed ID: 28642575 Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia Via P2Y Receptor Downregulation Cell Reports. 05, 2017 | Pubmed ID: 28494865 P2Y-deficiency Increases Micturition Frequency and Attenuates Sustained Contractility of the Urinary Bladder in Mice Scientific Reports. 04, 2017 | Pubmed ID: 28396595 Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa PloS One. 2017 | Pubmed ID: 28060940 The Clock Mutant Mouse is a Novel Experimental Model for Nocturia and Nocturnal Polyuria Neurourology and Urodynamics. Apr, 2017 | Pubmed ID: 27348079 Urothelial ATP Exocytosis: Regulation of Bladder Compliance in the Urine Storage Phase Scientific Reports. 07, 2016 | Pubmed ID: 27412485 Cortical Astrocytes Rewire Somatosensory Cortical Circuits for Peripheral Neuropathic Pain The Journal of Clinical Investigation. May, 2016 | Pubmed ID: 27064281 Probing the Complexities of Astrocyte Calcium Signaling Trends in Cell Biology. Apr, 2016 | Pubmed ID: 26896246 Müller Cell-mediated Neurite Outgrowth of the Retinal Ganglion Cells Via P2Y Receptor Signals Journal of Neurochemistry. Feb, 2016 | Pubmed ID: 26560804 Imaging Calcium Microdomains Within Entire Astrocyte Territories and Endfeet with GCaMPs Expressed Using Adeno-associated Viruses The Journal of General Physiology. May, 2013 | Pubmed ID: 23589582 TRPA1 Canales Regular El Calcio Astrocitos En Reposo Y Eficacia De La Sinapsis Inhibitoria A Través De TAG-3 Nature Neuroscience. Jan, 2012 | Pubmed ID: 22158513 Receptores Neuronales P2X2 Son Móviles Sensores ATP Que Exploran La Membrana Plasmática Cuando Se Activa The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2011 | Pubmed ID: 22090499 [Regulación Sináptica Por Astrocitos] Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Oct, 2011 | Pubmed ID: 21986065 Carga Masiva De Colorantes Indicadores De Calcio Para El Estudio De Los Astrocitos Fisiología: Limitaciones Y Mejoras Clave Uso De Mapas Morfológicos The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2011 | Pubmed ID: 21697385 Seguimiento De Microdominios De Astrocitos De Calcio Con La Membrana Mejorada Dirigida Reporteros GCaMP Neuron Glia Biology. Dec, 2010 | Pubmed ID: 21205365 Un Sensor óptico Genéticamente Selectiva Para Monitorear Las Señales De Calcio En Los Procesos De Los Astrocitos Nature Neuroscience. Jun, 2010 | Pubmed ID: 20495558 Dos Formas De Excitabilidad De Calcio Astrocitos Tener Efectos Diferentes En NMDA Mediados Por Receptores Corrientes De Entrada Lenta En Las Neuronas Piramidales The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2008 | Pubmed ID: 18579739 Seguimiento De Transmisor-cerrada De Cationes P2X Canal Activación in Vitro E in Vivo Nature Methods. Jan, 2008 | Pubmed ID: 18084300 [Complejo Regulador Purinérgicos En Las Sinapsis Del Cerebro] Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2007 | Pubmed ID: 17633523 Facilitación De La Liberación Espontánea De Glicina Por Anoxia Potencia Del Receptor NMDA En Las Hipoglosos De Las Neuronas Motoras De La Rata The European Journal of Neuroscience. Mar, 2007 | Pubmed ID: 17408431 Bloqueador Resistente Presinápticos Voltaje-dependiente Ca2 + Canales Subyacente Glutamato Liberan En Ratones Solitarii Del Tractus Del Brain Research. Aug, 2006 | Pubmed ID: 16814754 Un Doble Papel Había Desempeñado Por ATP Extracelular En Filtrado De Frecuencia Del Núcleo Del Tractus Folliculi Red Advances in Experimental Medicine and Biology. 2004 | Pubmed ID: 15602957 Independiente Del Potencial De Acción Liberación De Glutamato Por Entrada De Ca2 + a Través De Los Receptores P2X Presinápticos Produce Leña Postsináptica En La Red Autonómica De La Médula Oblonga The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2004 | Pubmed ID: 15044552 ATP - Y Adenosina-mediada De Señalización En El Sistema Nervioso Central: Purinoceptors Sináptica: La Etapa De ATP Jugar Su "doble Función" Journal of Pharmacological Sciences. Feb, 2004 | Pubmed ID: 14978346 Diferencial Aumenta En Los Niveles De Receptores P2X En Neuronas Eferentes Vagales De Rata Tras Una Sección Del Nervio Vago Brain Research. Jul, 2003 | Pubmed ID: 12788520 Análisis De Los Mecanismos Moleculares Que Controla La Transmisión Sináptica De Patch-clamp Grabación En Rebanadas De Tronco Encefálico Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Apr, 2003 | Pubmed ID: 12777844 In vivo Imágenes de calcio de campo amplio y dos fotones de un ratón usando una ventana craneal grande Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 Neuroscience Trasplante de microglía derivada de células madre pluripotentes inducidas por humanos en ratones cerebros inmunocompetentes a través de una ruta transnasal no invasiva Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 Neuroscience Cerca de la medición de la membrana plasmática y Global Dynamics calcio intracelular en los astrocitos Eiji Shigetomi1, Baljit S. Khakh1 1Departments of Physiology and Neurobiology, David Geffen School of Medicine, University of California, Los Angeles JoVE 1142 Biology
In vivo Imágenes de calcio de campo amplio y dos fotones de un ratón usando una ventana craneal grande Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 Neuroscience
Trasplante de microglía derivada de células madre pluripotentes inducidas por humanos en ratones cerebros inmunocompetentes a través de una ruta transnasal no invasiva Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 Neuroscience
Cerca de la medición de la membrana plasmática y Global Dynamics calcio intracelular en los astrocitos Eiji Shigetomi1, Baljit S. Khakh1 1Departments of Physiology and Neurobiology, David Geffen School of Medicine, University of California, Los Angeles JoVE 1142 Biology