Enno Klussman Biography Publications JoVE Articles Enno Klussman has not added a biography. If you are Enno Klussman and would like to personalize this page please email our Author Liaison for assistance. Publications SGN-CD33A: a Novel CD33-targeting Antibody-drug Conjugate Utilizing a Pyrrolobenzodiazepine Dimer is Active in Models of Drug-resistant AML Blood. Jun, 2013 | Pubmed ID: 23770776 Development of Orally Active Inhibitors of Protein and Cellular Fucosylation Proceedings of the National Academy of Sciences of the United States of America. Apr, 2013 | Pubmed ID: 23493549 Preclinical Characterization of SGN-70, a Humanized Antibody Directed Against CD70 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2008 | Pubmed ID: 19047103 Comparison of D-g3139 and Its Enantiomer L-g3139 in Melanoma Cells Demonstrates Minimal in Vitro but Dramatic in Vivo Chiral Dependency Molecular Therapy : the Journal of the American Society of Gene Therapy. Feb, 2007 | Pubmed ID: 17235304 Engineered Anti-CD70 Antibody with Multiple Effector Functions Exhibits in Vitro and in Vivo Antitumor Activities Blood. Feb, 2007 | Pubmed ID: 17038522 Preclinical Antilymphoma Activity of a Humanized Anti-CD40 Monoclonal Antibody, SGN-40 Cancer Research. Sep, 2005 | Pubmed ID: 16166310 Efficient Elimination of B-lineage Lymphomas by Anti-CD20-auristatin Conjugates Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Dec, 2004 | Pubmed ID: 15585616 Secondary MAb--vcMMAE Conjugates Are Highly Sensitive Reporters of Antibody Internalization Via the Lysosome Pathway Bioconjugate Chemistry. Jul-Aug, 2004 | Pubmed ID: 15264863 [Vascularized Tumor of the Scalp] HNO. Sep, 2003 | Pubmed ID: 14521156 CAC10-vcMMAE, an Anti-CD30-monomethyl Auristatin E Conjugate with Potent and Selective Antitumor Activity Blood. Aug, 2003 | Pubmed ID: 12714494 The Anti-CD30 Monoclonal Antibody SGN-30 Promotes Growth Arrest and DNA Fragmentation in Vitro and Affects Antitumor Activity in Models of Hodgkin's Disease Cancer Research. Jul, 2002 | Pubmed ID: 12097283 Anti-4-1BB Monoclonal Antibodies Abrogate T Cell-dependent Humoral Immune Responses in Vivo Through the Induction of Helper T Cell Anergy The Journal of Experimental Medicine. Nov, 1999 | Pubmed ID: 10562327 4-1BB Costimulatory Signals Preferentially Induce CD8+ T Cell Proliferation and Lead to the Amplification in Vivo of Cytotoxic T Cell Responses The Journal of Experimental Medicine. Jul, 1997 | Pubmed ID: 9206996 Surface Expression of CD28 Single Chain Fv for Costimulation by Tumor Cells Immunological Reviews. Oct, 1996 | Pubmed ID: 9010725 Crystallization and Preliminary Diffraction Studies of the Structural Domain E of Thermus Flavus 5S RRNA FEBS Letters. Oct, 1995 | Pubmed ID: 7589556 CD45-mediated Regulation of Extracellular Calcium Influx in a CD4-transfected Human T Cell Line Journal of Immunology (Baltimore, Md. : 1950). Jul, 1994 | Pubmed ID: 7515932 Costimulation of T Lymphocytes with Integrin Ligands Intercellular Adhesion Molecule-1 or Vascular Cell Adhesion Molecule-1 Induces Functional Expression of CTLA-4, a Second Receptor for B7 Journal of Immunology (Baltimore, Md. : 1950). Mar, 1994 | Pubmed ID: 7511623 Activation with Superantigens Induces Programmed Death in Antigen-primed CD4+ Class II+ Major Histocompatibility Complex T Lymphocytes Via a CD11a/CD18-dependent Mechanism European Journal of Immunology. Jul, 1993 | Pubmed ID: 8100773 Costimulation with Integrin Ligands Intercellular Adhesion Molecule-1 or Vascular Cell Adhesion Molecule-1 Augments Activation-induced Death of Antigen-specific CD4+ T Lymphocytes Journal of Immunology (Baltimore, Md. : 1950). Sep, 1993 | Pubmed ID: 7689606 Costimulation Via Vascular Cell Adhesion Molecule-1 Induces in T Cells Increased Responsiveness to the CD28 Counter-receptor B7 Cellular Immunology. Apr, 1993 | Pubmed ID: 7684325 Proliferation of Human T Lymphocytes Induced with Superantigens is Not Dependent on Costimulation by the CD28 Counter-receptor B7 Journal of Immunology (Baltimore, Md. : 1950). Feb, 1993 | Pubmed ID: 7678619 Differential Regulatory Effects of Intercellular Adhesion Molecule-1 on Costimulation by the CD28 Counter-receptor B7 Journal of Immunology (Baltimore, Md. : 1950). Oct, 1992 | Pubmed ID: 1383317 GMP-140 (P-selectin/CD62) Binds to Chronically Stimulated but Not Resting CD4+ T Lymphocytes and Regulates Their Production of Proinflammatory Cytokines European Journal of Immunology. Jul, 1992 | Pubmed ID: 1378017 Differential Costimulatory Effects of Adhesion Molecules B7, ICAM-1, LFA-3, and VCAM-1 on Resting and Antigen-primed CD4+ T Lymphocytes Journal of Immunology (Baltimore, Md. : 1950). Apr, 1992 | Pubmed ID: 1372018 Intercellular Adhesion Molecule-2, a Second Counter-receptor for CD11a/CD18 (leukocyte Function-associated Antigen-1), Provides a Costimulatory Signal for T-cell Receptor-initiated Activation of Human T Cells Journal of Immunology (Baltimore, Md. : 1950). Feb, 1992 | Pubmed ID: 1346150 Outpatient Dacryocystorhinostomy Ophthalmic Surgery. Apr, 1991 | Pubmed ID: 1772483 [Psychosomatic Medicine: Clinical Aspects] MMW, Münchener Medizinische Wochenschrift. Sep, 1982 | Pubmed ID: 6817083