Erik Serrao Department of Cancer Immunology and AIDS Dana-Farber Cancer Institute Biography Publications Institution JoVE Articles Erik Serrao has not added a biography. If you are Erik Serrao and would like to personalize this page please email our Author Liaison for assistance. Publications The Competitive Interplay Between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 During the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency ACS Chemical Biology. Mar, 2016 | Pubmed ID: 26910179 A Critical Role for Alternative Polyadenylation Factor CPSF6 in Targeting HIV-1 Integration to Transcriptionally Active Chromatin Proceedings of the National Academy of Sciences of the United States of America. Feb, 2016 | Pubmed ID: 26858452 Sites of Retroviral DNA Integration: From Basic Research to Clinical Applications Critical Reviews in Biochemistry and Molecular Biology. Jan-Feb, 2016 | Pubmed ID: 26508664 Structural Basis for Retroviral Integration into Nucleosomes Nature. Jul, 2015 | Pubmed ID: 26061770 Key Determinants of Target DNA Recognition by Retroviral Intasomes Retrovirology. 2015 | Pubmed ID: 25924943 Host and Viral Determinants for MxB Restriction of HIV-1 Infection Retrovirology. 2014 | Pubmed ID: 25348155 Molecular Mechanisms of Retroviral Integration Site Selection Nucleic Acids Research. 2014 | Pubmed ID: 25147212 Design and Discovery of Flavonoid-based HIV-1 Integrase Inhibitors Targeting Both the Active Site and the Interaction with LEDGF/p75 Bioorganic & Medicinal Chemistry. Jun, 2014 | Pubmed ID: 24794743 Integrase Residues That Determine Nucleotide Preferences at Sites of HIV-1 Integration: Implications for the Mechanism of Target DNA Binding Nucleic Acids Research. Apr, 2014 | Pubmed ID: 24520116 Alteration of Select Gene Expression Patterns in Individuals Infected with HIV-1 Journal of Medical Virology. Apr, 2014 | Pubmed ID: 24482297 Biochemical Characterization of Novel Retroviral Integrase Proteins PloS One. 2013 | Pubmed ID: 24124581 Discovery of a Novel 5-carbonyl-1H-imidazole-4-carboxamide Class of Inhibitors of the HIV-1 Integrase-LEDGF/p75 Interaction Bioorganic & Medicinal Chemistry. Oct, 2013 | Pubmed ID: 23985689 Fragment-based Discovery of 8-hydroxyquinoline Inhibitors of the HIV-1 Integrase-lens Epithelium-derived Growth Factor/p75 (IN-LEDGF/p75) Interaction Journal of Medicinal Chemistry. Mar, 2013 | Pubmed ID: 23445471 A Symmetric Region of the HIV-1 Integrase Dimerization Interface Is Essential for Viral Replication PloS One. 2012 | Pubmed ID: 23028829 HIV-1 Integrase Inhibitors: 2007-2008 Update Medicinal Research Reviews. Nov, 2010 | Pubmed ID: 20135632 Raltegravir, Elvitegravir, and Metoogravir: the Birth of "me-too" HIV-1 Integrase Inhibitors Retrovirology. 2009 | Pubmed ID: 19265512 Förstärkning, Nästa generations sekvensering, och Genomic DNA Kartläggning av retroviral integration webbplatser Erik Serrao1, Peter Cherepanov2, Alan N. Engelman1 1Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, 2Chromatin Structure and Mobile DNA, The Francis Crick Institute Biology
Förstärkning, Nästa generations sekvensering, och Genomic DNA Kartläggning av retroviral integration webbplatser Erik Serrao1, Peter Cherepanov2, Alan N. Engelman1 1Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, 2Chromatin Structure and Mobile DNA, The Francis Crick Institute Biology