Frank B. Furnari Ludwig Institute for Cancer Research Biography Publications Institution JoVE Articles Frank B. Furnari has not added a biography. If you are Frank B. Furnari and would like to personalize this page please email our Author Liaison for assistance. Publications Glioblastoma Cellular Cross-talk Converges on NF-κB to Attenuate EGFR Inhibitor Sensitivity Genes & Development. Jul, 2017 | Pubmed ID: 28724615 PTEN Regulates Glioblastoma Oncogenesis Through Chromatin-associated Complexes of DAXX and Histone H3.3 Nature Communications. May, 2017 | Pubmed ID: 28497778 Extrachromosomal Oncogene Amplification Drives Tumour Evolution and Genetic Heterogeneity Nature. 03, 2017 | Pubmed ID: 28178237 Inhibition of Radiation-induced Glioblastoma Invasion by Genetic and Pharmacological Targeting of MDA-9/Syntenin Proceedings of the National Academy of Sciences of the United States of America. 01, 2017 | Pubmed ID: 28011764 Simultaneous Blockade of Interacting CK2 and EGFR Pathways by Tumor-targeting Nanobioconjugates Increases Therapeutic Efficacy Against Glioblastoma Multiforme Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2016 | Pubmed ID: 27825958 An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers Cancer Cell. Nov, 2016 | Pubmed ID: 27746144 The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System Xc(-) Cancer Research. 05, 2016 | Pubmed ID: 26980765 EGFR Mutation Promotes Glioblastoma Through Epigenome and Transcription Factor Network Remodeling Molecular Cell. Oct, 2015 | Pubmed ID: 26455392 Orthogonal Targeting of EGFRvIII Expressing Glioblastomas Through Simultaneous EGFR and PLK1 Inhibition Oncotarget. May, 2015 | Pubmed ID: 26059434 Heterogeneity of Epidermal Growth Factor Receptor Signalling Networks in Glioblastoma Nature Reviews. Cancer. May, 2015 | Pubmed ID: 25855404 Cancer-associated Protein Kinase C Mutations Reveal Kinase's Role As Tumor Suppressor Cell. Jan, 2015 | Pubmed ID: 25619690 A Urokinase Receptor-Bim Signaling Axis Emerges During EGFR Inhibitor Resistance in Mutant EGFR Glioblastoma Cancer Research. Jan, 2015 | Pubmed ID: 25432173 A Unified Nomenclature and Amino Acid Numbering for Human PTEN Science Signaling. Jul, 2014 | Pubmed ID: 24985344 Suppression of MicroRNA-9 by Mutant EGFR Signaling Upregulates FOXP1 to Enhance Glioblastoma Tumorigenicity Cancer Research. Mar, 2014 | Pubmed ID: 24436148 Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA Science (New York, N.Y.). Jan, 2014 | Pubmed ID: 24310612 Therapeutic Resistance in Cancer: MicroRNA Regulation of EGFR Signaling Networks Cancer Biology & Medicine. Dec, 2013 | Pubmed ID: 24349829 The MTOR Kinase Inhibitors, CC214-1 and CC214-2, Preferentially Block the Growth of EGFRvIII-activated Glioblastomas Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2013 | Pubmed ID: 24030701 A Tale of Two Approaches: Complementary Mechanisms of Cytotoxic and Targeted Therapy Resistance May Inform Next-generation Cancer Treatments Carcinogenesis. Apr, 2013 | Pubmed ID: 23455378 Resistencia a Los Inhibidores Del Receptor De EGF En Glioblastoma Mediada Por La Fosforilación Del Supresor Del Tumor De PTEN En Tirosina 240 Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22891331 La Activación De Src Induce Localización Mitocondrial De DE2-7EGFR (EGFRvIII) En Células De Glioma: Implicaciones Para El Metabolismo De La Glucosa Journal of Cell Science. Sep, 2011 | Pubmed ID: 21878501 Report from the Fifth National Cancer Institute Mouse Models of Human Cancers Consortium Nervous System Tumors Workshop Neuro-oncology. Jul, 2011 | Pubmed ID: 21727208 Malignant Astrocytic Glioma: Genetics, Biology, and Paths to Treatment Genes & Development. Nov, 2007 | Pubmed ID: 17974913 La Eficacia De Factor De Crecimiento Epidérmico Receptor Específico-anticuerpos Contra Xenoinjertos De Glioma Es Influida Por Los Niveles De Receptores, Estado De Activación, Y Heterodimerización Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Mar, 2007 | Pubmed ID: 17363548 PCAF Modulates PTEN Activity The Journal of Biological Chemistry. Sep, 2006 | Pubmed ID: 16829519 El Tratamiento De Xenoinjertos Tumorales Humanos Con El Anticuerpo Monoclonal 806 En Combinación Con Un Factor De Crecimiento Epidérmico Prototípico Receptor Específico De Anticuerpo Genera Una Actividad Antitumoral Mejorada Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2005 | Pubmed ID: 16144944 PTEN: a Novel Anti-oncogenic Function Independent of Phosphatase Activity Cell Cycle (Georgetown, Tex.). Apr, 2005 | Pubmed ID: 15753657 Cellular Transformation by the MSP58 Oncogene is Inhibited by Its Physical Interaction with the PTEN Tumor Suppressor Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15659546 Alix/AIP1 Antagoniza Downregulation Del Receptor Del Factor De Crecimiento Epidérmico Por El Complejo De Cbl-SETA/CIN85 Molecular and Cellular Biology. Oct, 2004 | Pubmed ID: 15456872 Mutant Epidermal Growth Factor Receptor Signaling Down-regulates P27 Through Activation of the Phosphatidylinositol 3-kinase/Akt Pathway in Glioblastomas Cancer Research. Nov, 2002 | Pubmed ID: 12438278 Un Nuevo Receptor Transmembrana Siete Inducida Durante Los Primeros Pasos De La Diferenciación De Astrositos Identificados Por Expresión Diferencial Journal of Neurochemistry. May, 2002 | Pubmed ID: 12065666 The Phosphoinositol Phosphatase Activity of PTEN Mediates a Serum-sensitive G1 Growth Arrest in Glioma Cells Cancer Research. Nov, 1998 | Pubmed ID: 9823298 In Vitro Loss of Heterozygosity Targets the PTEN/MMAC1 Gene in Melanoma Proceedings of the National Academy of Sciences of the United States of America. Aug, 1998 | Pubmed ID: 9689095 Growth Suppression of Glioma Cells by PTEN Requires a Functional Phosphatase Catalytic Domain Proceedings of the National Academy of Sciences of the United States of America. Nov, 1997 | Pubmed ID: 9356475 Tomografía Molecular de la fluorescencia para obtener imágenes In Vivo de xenoinjertos de Glioblastoma Jorge A. Benitez*1, Ciro Zanca*1, Jianhui Ma1, Webster K. Cavenee1,2,3, Frank B. Furnari1,2,4 1Ludwig Institute for Cancer Research, 2Moores Cancer Center, School of Medicine, University of California, San Diego, 3Department of Pathology, School of Medicine, University of California, San Diego, 4Department of Medicine, School of Medicine, University of California, San Diego JoVE 57448 Cancer Research
Tomografía Molecular de la fluorescencia para obtener imágenes In Vivo de xenoinjertos de Glioblastoma Jorge A. Benitez*1, Ciro Zanca*1, Jianhui Ma1, Webster K. Cavenee1,2,3, Frank B. Furnari1,2,4 1Ludwig Institute for Cancer Research, 2Moores Cancer Center, School of Medicine, University of California, San Diego, 3Department of Pathology, School of Medicine, University of California, San Diego, 4Department of Medicine, School of Medicine, University of California, San Diego JoVE 57448 Cancer Research