Gianrico Farrugia Enteric Neuroscience Program, Division of Gastroenterology & Hepatology,Department of Physiology & Biomedical Engineering Mayo Clinic Biography Publications Institution JoVE Articles Gianrico Farrugia has not added a biography. If you are Gianrico Farrugia and would like to personalize this page please email our Author Liaison for assistance. Publications Introducing Our Associates Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. Mar, 2013 | Pubmed ID: 23480275 Cholecystectomy and Clinical Presentations of Gastroparesis Digestive Diseases and Sciences. Mar, 2013 | Pubmed ID: 23456496 Complex Interactions Among Diet, Gastrointestinal Transit, and Gut Microbiota in Humanized Mice Gastroenterology. Feb, 2013 | Pubmed ID: 23380084 Kit Signaling Is Required for Development of Coordinated Motility Patterns in Zebrafish Gastrointestinal Tract Zebrafish. Jan, 2013 | Pubmed ID: 23297728 Intractable Nausea and Vomiting from Autoantibodies Against a Brain Water Channel Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Mar, 2013 | Pubmed ID: 23211959 Age Sensitizes the Kidney to Heme Protein-induced Acute Kidney Injury American Journal of Physiology. Renal Physiology. Feb, 2013 | Pubmed ID: 23195679 Endoscopic Full-thickness Biopsy of the Gastric Wall with Defect Closure by Using an Endoscopic Suturing Device: Survival Porcine Study Gastrointestinal Endoscopy. Nov, 2012 | Pubmed ID: 23078926 Ranolazine Inhibits Shear Sensitivity of Endogenous Na+ Current and Spontaneous Action Potentials in HL-1 Cells Channels (Austin, Tex.). Nov-Dec, 2012 | Pubmed ID: 23018927 Inhibition of Cell Proliferation by a Selective Inhibitor of the Ca(2+)-activated Cl(-) Channel, Ano1 Biochemical and Biophysical Research Communications. Oct, 2012 | Pubmed ID: 22995309 Toward Biphasic Computed Tomography (CT) Enteric Contrast: Material Classification of Luminal Bismuth and Mural Iodine in a Small-bowel Phantom Using Dual-energy CT Journal of Computer Assisted Tomography. Sep, 2012 | Pubmed ID: 22992606 Membrane Permeable Local Anesthetics Modulate Na(V)1.5 Mechanosensitivity Channels (Austin, Tex.). Jul-Aug, 2012 | Pubmed ID: 22874086 Abnormal Initiation and Conduction of Slow-wave Activity in Gastroparesis, Defined by High-resolution Electrical Mapping Gastroenterology. Sep, 2012 | Pubmed ID: 22643349 The Places to Be for Neurogastroenterologists Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. Jun, 2012 | Pubmed ID: 22583599 Ranolazine Decreases Mechanosensitivity of the Voltage-gated Sodium Ion Channel Na(v)1.5: a Novel Mechanism of Drug Action Circulation. Jun, 2012 | Pubmed ID: 22565935 Targeting Ion Channels for the Treatment of Gastrointestinal Motility Disorders Therapeutic Advances in Gastroenterology. Jan, 2012 | Pubmed ID: 22282704 Quantification of Gastrointestinal Sodium Channelopathy Journal of Theoretical Biology. Jan, 2012 | Pubmed ID: 21959314 Ultrastructural Differences Between Diabetic and Idiopathic Gastroparesis Journal of Cellular and Molecular Medicine. Jul, 2012 | Pubmed ID: 21914127 Hydrogen Sulfide Modulates Contractile Function in Rat Jejunum The Journal of Surgical Research. Jun, 2012 | Pubmed ID: 21571312 Inhaled Carbon Monoxide Attenuates Myocardial Inflammatory Cytokine Expression in a Rat Model of Cardiopulmonary Bypass The Journal of Extra-corporeal Technology. Sep, 2011 | Pubmed ID: 22164452 Ano1 As a Regulator of Proliferation American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2011 | Pubmed ID: 21940901 Similarities and Differences Between Diabetic and Idiopathic Gastroparesis Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Dec, 2011 | Pubmed ID: 21871247 A Stochastic Multi-scale Model of Electrical Function in Normal and Depleted ICC Networks IEEE Transactions on Bio-medical Engineering. Dec, 2011 | Pubmed ID: 21843981 Biophysically Based Modeling of the Interstitial Cells of Cajal: Current Status and Future Perspectives Frontiers in Physiology. 2011 | Pubmed ID: 21772822 Dietary Intake and Nutritional Deficiencies in Patients with Diabetic or Idiopathic Gastroparesis Gastroenterology. Aug, 2011 | Pubmed ID: 21684286 Loss of NRF2 Impairs Gastric Nitrergic Stimulation and Function Free Radical Biology & Medicine. Aug, 2011 | Pubmed ID: 21605664 Reply Gastroenterology. Apr, 2011 | Pubmed ID: 21540031 Bloating in Gastroparesis: Severity, Impact, and Associated Factors The American Journal of Gastroenterology. Aug, 2011 | Pubmed ID: 21483459 Characteristics of Patients with Chronic Unexplained Nausea and Vomiting and Normal Gastric Emptying Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Jul, 2011 | Pubmed ID: 21397732 Hydrogen Sulfide is a Partially Redox-independent Activator of the Human Jejunum Na+ Channel, Nav1.5 American Journal of Physiology. Gastrointestinal and Liver Physiology. Jun, 2011 | Pubmed ID: 21393430 Gastrointestinal Neuromuscular Pathology in Chronic Constipation Best Practice & Research. Clinical Gastroenterology. Feb, 2011 | Pubmed ID: 21382578 Altered Expression of Ano1 Variants in Human Diabetic Gastroparesis The Journal of Biological Chemistry. Apr, 2011 | Pubmed ID: 21349842 Cellular Changes in Diabetic and Idiopathic Gastroparesis Gastroenterology. May, 2011 | Pubmed ID: 21300066 Esophageal Papillomas and Skin Abnormalities. Focal Dermal Hypoplasia (Goltz Syndrome) Manifesting with Esophageal Papillomatosis Gastroenterology. Mar, 2011 | Pubmed ID: 21272558 Clinical Features of Idiopathic Gastroparesis Vary with Sex, Body Mass, Symptom Onset, Delay in Gastric Emptying, and Gastroparesis Severity Gastroenterology. Jan, 2011 | Pubmed ID: 20965184 Epidemiology, Mechanisms, and Management of Diabetic Gastroparesis Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. Jan, 2011 | Pubmed ID: 20951838 Mechanosensitivity of Nav1.5, a Voltage-sensitive Sodium Channel The Journal of Physiology. Dec, 2010 | Pubmed ID: 21041530 Diabetic Gastroparesis: What We Have Learned and Had to Unlearn in the Past 5 Years Gut. Dec, 2010 | Pubmed ID: 20871131 Kitlow Stem Cells Cause Resistance to Kit/platelet-derived Growth Factor Alpha Inhibitors in Murine Gastrointestinal Stromal Tumors Gastroenterology. Sep, 2010 | Pubmed ID: 20621681 Psychological Dysfunction is Associated with Symptom Severity but Not Disease Etiology or Degree of Gastric Retention in Patients with Gastroparesis The American Journal of Gastroenterology. Nov, 2010 | Pubmed ID: 20588262 The London Classification of Gastrointestinal Neuromuscular Pathology: Report on Behalf of the Gastro 2009 International Working Group Gut. Jul, 2010 | Pubmed ID: 20581236 Loss of Kitlow Progenitors, Reduced Stem Cell Factor and High Oxidative Stress Underlie Gastric Dysfunction in Progeric Mice The Journal of Physiology. Aug, 2010 | Pubmed ID: 20581042 Tissue-specific Mathematical Models of Slow Wave Entrainment in Wild-type and 5-HT(2B) Knockout Mice with Altered Interstitial Cells of Cajal Networks Biophysical Journal. May, 2010 | Pubmed ID: 20441740 Carbon Monoxide Reverses Diabetic Gastroparesis in NOD Mice American Journal of Physiology. Gastrointestinal and Liver Physiology. Jun, 2010 | Pubmed ID: 20378827 T-type Ca(2+) Channel Modulation by Otilonium Bromide American Journal of Physiology. Gastrointestinal and Liver Physiology. May, 2010 | Pubmed ID: 20203058 CD206-positive M2 Macrophages That Express Heme Oxygenase-1 Protect Against Diabetic Gastroparesis in Mice Gastroenterology. Jun, 2010 | Pubmed ID: 20178793 The Mayo Dysphagia Questionnaire-30: Documentation of Reliability and Validity of a Tool for Interventional Trials in Adults with Esophageal Disease Dysphagia. Sep, 2010 | Pubmed ID: 19856027 Endogenous Production of H2S in the Gastrointestinal Tract: Still in Search of a Physiologic Function Antioxidants & Redox Signaling. May, 2010 | Pubmed ID: 19769466 Neural Autoantibody Profile of Primary Achalasia Digestive Diseases and Sciences. Feb, 2010 | Pubmed ID: 19499338 Physiology, Injury, and Recovery of Interstitial Cells of Cajal: Basic and Clinical Science Gastroenterology. Nov, 2009 | Pubmed ID: 19778538 Protein Kinase C{gamma} Mediates Regulation of Proliferation by the Serotonin 5-hydroxytryptamine Receptor 2B The Journal of Biological Chemistry. Aug, 2009 | Pubmed ID: 19531484 The Alpha1H Ca2+ Channel Subunit is Expressed in Mouse Jejunal Interstitial Cells of Cajal and Myocytes Journal of Cellular and Molecular Medicine. Nov-Dec, 2009 | Pubmed ID: 19413888 Ano1 is a Selective Marker of Interstitial Cells of Cajal in the Human and Mouse Gastrointestinal Tract American Journal of Physiology. Gastrointestinal and Liver Physiology. Jun, 2009 | Pubmed ID: 19372102 Gastrointestinal Neuromuscular Pathology: Guidelines for Histological Techniques and Reporting on Behalf of the Gastro 2009 International Working Group Acta Neuropathologica. Aug, 2009 | Pubmed ID: 19360428 Diagnostic Challenges of Motility Disorders: Optimal Detection of CD117+ Interstitial Cells of Cajal Histopathology. Feb, 2009 | Pubmed ID: 19236504 Lysophosphatidyl Choline Modulates Mechanosensitive L-type Ca2+ Current in Circular Smooth Muscle Cells from Human Jejunum American Journal of Physiology. Gastrointestinal and Liver Physiology. Apr, 2009 | Pubmed ID: 19179622 Sodium Channel Mutation in Irritable Bowel Syndrome: Evidence for an Ion Channelopathy American Journal of Physiology. Gastrointestinal and Liver Physiology. Feb, 2009 | Pubmed ID: 19056759 Heme Oxygenase-1 Protects Interstitial Cells of Cajal from Oxidative Stress and Reverses Diabetic Gastroparesis Gastroenterology. Dec, 2008 | Pubmed ID: 18926825 Syntrophin Mutation Associated with Long QT Syndrome Through Activation of the NNOS-SCN5A Macromolecular Complex Proceedings of the National Academy of Sciences of the United States of America. Jul, 2008 | Pubmed ID: 18591664 Changes in the Gastric Enteric Nervous System and Muscle: a Case Report on Two Patients with Diabetic Gastroparesis BMC Gastroenterology. 2008 | Pubmed ID: 18513423 Production of the Gaseous Signal Molecule Hydrogen Sulfide in Mouse Tissues Journal of Neurochemistry. Aug, 2008 | Pubmed ID: 18513201 Enteric Autoantibodies and Gut Motility Disorders Gastroenterology Clinics of North America. Jun, 2008 | Pubmed ID: 18499027 A Mutation in Telethonin Alters Nav1.5 Function The Journal of Biological Chemistry. Jun, 2008 | Pubmed ID: 18408010 Endoscopic "no Hole" Full-thickness Biopsy of the Stomach to Detect Myenteric Ganglia Gastrointestinal Endoscopy. Aug, 2008 | Pubmed ID: 18262183 Evaluation of Endoscopic Approaches for Deep Gastric-muscle-wall Biopsies: What Works? Gastrointestinal Endoscopy. Feb, 2008 | Pubmed ID: 18028922 Evolving Concepts in the Cellular Control of Gastrointestinal Motility: Neurogastroenterology and Enteric Sciences Gastroenterology Clinics of North America. Sep, 2007 | Pubmed ID: 17950435 Determination of Gastric Emptying in Nonobese Diabetic Mice American Journal of Physiology. Gastrointestinal and Liver Physiology. Nov, 2007 | Pubmed ID: 17884976 Exogenous Serotonin Regulates Proliferation of Interstitial Cells of Cajal in Mouse Jejunum Through 5-HT2B Receptors Gastroenterology. Sep, 2007 | Pubmed ID: 17854596 Mechanisms of Disease: the Pathological Basis of Gastroparesis--a Review of Experimental and Clinical Studies Nature Clinical Practice. Gastroenterology & Hepatology. Jun, 2007 | Pubmed ID: 17541447 Membrane Potential Gradient is Carbon Monoxide-dependent in Mouse and Human Small Intestine American Journal of Physiology. Gastrointestinal and Liver Physiology. Aug, 2007 | Pubmed ID: 17510199 Ca2+ Handling in Human Interstitial Cells of Cajal Gastroenterology. May, 2007 | Pubmed ID: 17484898 Serotonergic Modulation of Murine Fundic Tone American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2006 | Pubmed ID: 16873894 Gastrointestinal Symptoms in Families of Patients with an SCN5A-encoded Cardiac Channelopathy: Evidence of an Intestinal Channelopathy The American Journal of Gastroenterology. Jun, 2006 | Pubmed ID: 16771953 Defects in CGMP-PKG Pathway Contribute to Impaired NO-dependent Responses in Hepatic Stellate Cells Upon Activation American Journal of Physiology. Gastrointestinal and Liver Physiology. Mar, 2006 | Pubmed ID: 16269521 Effect of Modulation of Serotonergic, Cholinergic, and Nitrergic Pathways on Murine Fundic Size and Compliance Measured by Ultrasonomicrometry American Journal of Physiology. Gastrointestinal and Liver Physiology. Jan, 2006 | Pubmed ID: 16166345 Deciphering the Molecular Basis for the Pacemaker Signal Gastroenterology. Nov, 2005 | Pubmed ID: 16285975 Effect of Mibefradil on Sodium and Calcium Currents American Journal of Physiology. Gastrointestinal and Liver Physiology. Aug, 2005 | Pubmed ID: 15790762 Intercellular Coupling of Interstitial Cells of Cajal in the Digestive Tract International Review of Cytology. 2005 | Pubmed ID: 15598471 Carbon Monoxide Activates Human Intestinal Smooth Muscle L-type Ca2+ Channels Through a Nitric Oxide-dependent Mechanism American Journal of Physiology. Gastrointestinal and Liver Physiology. Jan, 2005 | Pubmed ID: 15319183 Meal-induced Dysphagia and Otalgia Secondary to a Pyriform Sinus Fistula Digestive Diseases and Sciences. Sep, 2004 | Pubmed ID: 15481338 Nitric Oxide in Gastrointestinal Health and Disease Gastroenterology. Mar, 2004 | Pubmed ID: 14988844 The Role of Carbon Monoxide in the Gastrointestinal Tract The Journal of Physiology. Apr, 2004 | Pubmed ID: 14766943 Heme: a Determinant of Life and Death in Renal Tubular Epithelial Cells American Journal of Physiology. Renal Physiology. Feb, 2004 | Pubmed ID: 14707007 Ion Channels in Gastrointestinal Smooth Muscle and Interstitial Cells of Cajal Current Opinion in Pharmacology. Dec, 2003 | Pubmed ID: 14644008 Sodium Current in Human Intestinal Interstitial Cells of Cajal American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2003 | Pubmed ID: 12893628 A Major Role for Carbon Monoxide As an Endogenous Hyperpolarizing Factor in the Gastrointestinal Tract Proceedings of the National Academy of Sciences of the United States of America. Jul, 2003 | Pubmed ID: 12832617 Cholinergic Denervation in Diverticular Disease Lancet. Jun, 2003 | Pubmed ID: 12801731 Chronic Intestinal Pseudoobstruction Associated with Altered Interstitial Cells of Cajal Networks Journal of Pediatric Gastroenterology and Nutrition. Apr, 2003 | Pubmed ID: 12658043 Cytoskeletal Modulation of Sodium Current in Human Jejunal Circular Smooth Muscle Cells American Journal of Physiology. Cell Physiology. Jan, 2003 | Pubmed ID: 12475760 Syntrophin Gamma 2 Regulates SCN5A Gating by a PDZ Domain-mediated Interaction The Journal of Biological Chemistry. Jan, 2003 | Pubmed ID: 12429735 The Kv2.2 Alpha Subunit Contributes to Delayed Rectifier K(+) Currents in Myocytes from Rabbit Corpus Cavernosum Journal of Andrology. Nov-Dec, 2002 | Pubmed ID: 12399537 Alpha(1C) (Ca(V)1.2) L-type Calcium Channel Mediates Mechanosensitive Calcium Regulation American Journal of Physiology. Cell Physiology. Sep, 2002 | Pubmed ID: 12176756 Paraneoplastic Dysmotility: Loss of Interstitial Cells of Cajal The American Journal of Gastroenterology. Jul, 2002 | Pubmed ID: 12135044 Sodium Current in Human Jejunal Circular Smooth Muscle Cells Gastroenterology. Jan, 2002 | Pubmed ID: 11781292 Tüm cep telefonu Elektrofizyoloji birincil kültürlü fare Enterochromaffin hücre Katilyn Knutson*1, Peter R. Strege*1, Joyce Li2, Andrew B. Leiter2, Gianrico Farrugia1, Arthur Beyder1 1Enteric Neuroscience Program, Division of Gastroenterology & Hepatology,Department of Physiology & Biomedical Engineering, Mayo Clinic, 2Division of Gastroenterology, Department of Medicine, University of Massachusetts Medical School JoVE 58112 Biology Bir Kullanarak Non-obez Diyabetik Farelerde Mide boşaltılması Değerlendirilmesi [ Christopher T. Creedon1, Pieter-Jan Verhulst1, Kyoung M. Choi1, Jessica E. Mason1, David R. Linden1, Joseph H. Szurszewski1, Simon J. Gibbons1, Gianrico Farrugia1 1Enteric Neuroscience Program, Department of Physiology and Biomedical Engineering, Mayo Clinic JoVE 50301 Medicine
Tüm cep telefonu Elektrofizyoloji birincil kültürlü fare Enterochromaffin hücre Katilyn Knutson*1, Peter R. Strege*1, Joyce Li2, Andrew B. Leiter2, Gianrico Farrugia1, Arthur Beyder1 1Enteric Neuroscience Program, Division of Gastroenterology & Hepatology,Department of Physiology & Biomedical Engineering, Mayo Clinic, 2Division of Gastroenterology, Department of Medicine, University of Massachusetts Medical School JoVE 58112 Biology
Bir Kullanarak Non-obez Diyabetik Farelerde Mide boşaltılması Değerlendirilmesi [ Christopher T. Creedon1, Pieter-Jan Verhulst1, Kyoung M. Choi1, Jessica E. Mason1, David R. Linden1, Joseph H. Szurszewski1, Simon J. Gibbons1, Gianrico Farrugia1 1Enteric Neuroscience Program, Department of Physiology and Biomedical Engineering, Mayo Clinic JoVE 50301 Medicine