Hiroyuki Nakai

Department of Molecular and Medical Genetics, Oregon Health & Science University

Affiliated withOregon Health & Science University Oregon National Primate Research Center

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 3	2018
Publication title	2025

Other Publications

Article	Year
Large-scale molecular characterization of adeno-associated virus vector integration in mouse liver. Journal of virology\| PubMed ID: 15731255	2005
AAV vectors containing rDNA homology display increased chromosomal integration and transgene persistence. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 22990673	2012
Adeno-associated virus serotype 8 (AAV8) delivery of recombinant A20 to skeletal muscle reduces pathological activation of nuclear factor (NF)-κB in muscle of mdx mice. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 23154638	2013
Intraganglionic AAV6 results in efficient and long-term gene transfer to peripheral sensory nervous system in adult rats. PloS one\| PubMed ID: 23613824	2013
An experimental and computational evolution-based method to study a mode of co-evolution of overlapping open reading frames in the AAV2 viral genome. PloS one\| PubMed ID: 23826091	2013
Drawing a high-resolution functional map of adeno-associated virus capsid by massively parallel sequencing. Nature communications\| PubMed ID: 24435020	2014
Identification and characterization of nuclear and nucleolar localization signals in the adeno-associated virus serotype 2 assembly-activating protein. Journal of virology\| PubMed ID: 25552709	2015
Adeno-associated Virus (AAV) Assembly-Activating Protein Is Not an Essential Requirement for Capsid Assembly of AAV Serotypes 4, 5, and 11. Journal of virology\| PubMed ID: 27852862	2017
Engineering a gene silencing viral construct that targets the cat hypothalamus to induce permanent sterility: An update. Reproduction in domestic animals = Zuchthygiene\| PubMed ID: 27859771	2017
Site-directed RNA repair of endogenous Mecp2 RNA in neurons. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 29078406	2017
Codon-Optimization of Wild-Type Adeno-Associated Virus Capsid Sequences Enhances DNA Family Shuffling while Conserving Functionality. Molecular therapy. Methods & clinical development\| PubMed ID: 30534580	2019
Adeno-associated virus-binding antibodies detected in cats living in the Northeastern United States lack neutralizing activity. Scientific reports\| PubMed ID: 32572045	2020
In Vivo Repair of a Protein Underlying a Neurological Disorder by Programmable RNA Editing. Cell reports\| PubMed ID: 32668243	2020
Multicolor labeling of airway neurons and analysis of parasympathetic heterogeneity. Scientific reports\| PubMed ID: 35322058	2022
AAV-vector based gene therapy for mitochondrial disease: progress and future perspectives. Orphanet journal of rare diseases\| PubMed ID: 35668433	2022
Expression of a Secretable, Cell-Penetrating CDKL5 Protein Enhances the Efficacy of Gene Therapy for CDKL5 Deficiency Disorder. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics\| PubMed ID: 36109452	2022
Genomic loss of GPR108 disrupts AAV transduction in birds. bioRxiv : the preprint server for biology\| PubMed ID: 38798475	2024
AAV Capsid Screening for Translational Pig Research Using a Mouse Xenograft Liver Model. bioRxiv : the preprint server for biology\| PubMed ID: 38853940	2024
Enhancing gene transfer to renal tubules and podocytes by context-dependent selection of AAV capsids. Nature communications\| PubMed ID: 39737896	2024