Javier González-Maeso

Publications

• Cross-signaling in Metabotropic Glutamate 2 and Serotonin 2A Receptor Heteromers in Mammalian Cells
  Pflügers Archiv : European Journal of Physiology. May, 2016  |   Pubmed ID: 26780666
• Allosteric Signaling Through an MGlu2 and 5-HT2A Heteromeric Receptor Complex and Its Potential Contribution to Schizophrenia
  Science Signaling. Jan, 2016  |   Pubmed ID: 26758213
• Positive Allosteric Modulators of Metabotropic Glutamate 2 Receptors in Schizophrenia Treatment
  Trends in Neurosciences. Aug, 2015  |   Pubmed ID: 26148747
• Epigenetic Signaling in Schizophrenia
  Cellular Signalling. Oct, 2015  |   Pubmed ID: 26120009
• Epigenetic Mechanisms of Serotonin Signaling
  ACS Chemical Neuroscience. Jul, 2015  |   Pubmed ID: 25734378
• G Protein-coupled Receptor Signaling to Kir Channels in Xenopus Oocytes
  Current Pharmaceutical Biotechnology. 2014  |   Pubmed ID: 25374032
• Family a GPCR Heteromers in Animal Models
  Frontiers in Pharmacology. 2014  |   Pubmed ID: 25346690
• Evaluation of 5-HT2A and MGlu2/3 Receptors in Postmortem Prefrontal Cortex of Subjects with Major Depressive Disorder: Effect of Antidepressant Treatment
  Neuropharmacology. Nov, 2014  |   Pubmed ID: 25150943
• Preclinical Models of Antipsychotic Drug Action
  The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (CINP). Nov, 2013  |   Pubmed ID: 23745738
• The HIV Antiretroviral Drug Efavirenz Has LSD-like Properties
  Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Nov, 2013  |   Pubmed ID: 23702798
• G Protein-coupled Receptor Heterocomplexes in Neuropsychiatric Disorders
  Progress in Molecular Biology and Translational Science. 2013  |   Pubmed ID: 23663970
• Repressive Epigenetic Changes at the MGlu2 Promoter in Frontal Cortex of 5-HT2A Knockout Mice
  Molecular Pharmacology. Jun, 2013  |   Pubmed ID: 23508685
• Epigenetic Regulation of RAC1 Induces Synaptic Remodeling in Stress Disorders and Depression
  Nature Medicine. Mar, 2013  |   Pubmed ID: 23416703
• Animal Models of Serotonergic Psychedelics
  ACS Chemical Neuroscience. Jan, 2013  |   Pubmed ID: 23336043
• Chronic Treatment with LY341495 Decreases 5-HT(2A) Receptor Binding and Hallucinogenic Effects of LSD in Mice
  Neuroscience Letters. Mar, 2013  |   Pubmed ID: 23333599
• Prenatal Stress Induces Schizophrenia-like Alterations of Serotonin 2A and Metabotropic Glutamate 2 Receptors in the Adult Offspring: Role of Maternal Immune System
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jan, 2013  |   Pubmed ID: 23325246
• HDAC2 As a New Target to Improve Schizophrenia Treatment
  Expert Review of Neurotherapeutics. Jan, 2013  |   Pubmed ID: 23253383
• Dysregulated 5-HT(2A) Receptor Binding in Postmortem Frontal Cortex of Schizophrenic Subjects
  European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. Aug, 2013  |   Pubmed ID: 23176747
• Persistent Effects of Chronic Clozapine on the Cellular and Behavioral Responses to LSD in Mice
  Psychopharmacology. Jan, 2013  |   Pubmed ID: 22842765
• Identification of Three Residues Essential for 5-hydroxytryptamine 2A-metabotropic Glutamate 2 (5-HT2A·mGlu2) Receptor Heteromerization and Its Psychoactive Behavioral Function
  The Journal of Biological Chemistry. Dec, 2012  |   Pubmed ID: 23129762
• HDAC2 Regulates Atypical Antipsychotic Responses Through the Modulation of MGlu2 Promoter Activity
  Nature Neuroscience. Sep, 2012  |   Pubmed ID: 22864611
• Reduced Levels of Serotonin 2A Receptors Underlie Resistance of Egr3-deficient Mice to Locomotor Suppression by Clozapine
  Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Sep, 2012  |   Pubmed ID: 22692564
• Decoding the Signaling of a GPCR Heteromeric Complex Reveals a Unifying Mechanism of Action of Antipsychotic Drugs
  Cell. Nov, 2011  |   Pubmed ID: 22118459
• Functional Crosstalk and Heteromerization of Serotonin 5-HT2A and Dopamine D2 Receptors
  Neuropharmacology. Sep, 2011  |   Pubmed ID: 21645528
• GPCR Oligomers in Pharmacology and Signaling
  Molecular Brain. 2011  |   Pubmed ID: 21619615
• Maternal Influenza Viral Infection Causes Schizophrenia-like Alterations of 5-HT₂A and MGlu₂ Receptors in the Adult Offspring
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2011  |   Pubmed ID: 21289196
• Metabotropic Glutamate MGlu2 Receptor is Necessary for the Pharmacological and Behavioral Effects Induced by Hallucinogenic 5-HT2A Receptor Agonists
  Neuroscience Letters. Apr, 2011  |   Pubmed ID: 21276828
• α₂-Adrenoceptor Functionality in Postmortem Frontal Cortex of Depressed Suicide Victims
  Biological Psychiatry. Nov, 2010  |   Pubmed ID: 20864091
• Heteromerization of G Protein-coupled Receptors: Relevance to Neurological Disorders and Neurotherapeutics
  CNS & Neurological Disorders Drug Targets. Nov, 2010  |   Pubmed ID: 20632964
• Anxious Interactions
  Nature Neuroscience. May, 2010  |   Pubmed ID: 20421895
• Group II Metabotropic Glutamate Receptors and Schizophrenia
  Cellular and Molecular Life Sciences : CMLS. Dec, 2009  |   Pubmed ID: 19707855
• Agonist-trafficking and Hallucinogens
  Current Medicinal Chemistry. 2009  |   Pubmed ID: 19275609
• Psychedelics and Schizophrenia
  Trends in Neurosciences. Apr, 2009  |   Pubmed ID: 19269047
• Receptor Pair for Schizophrenia
  Pediatric Research. Jul, 2008  |   Pubmed ID: 18574404
• Identification of a Serotonin/glutamate Receptor Complex Implicated in Psychosis
  Nature. Mar, 2008  |   Pubmed ID: 18297054
• Hallucinogens Recruit Specific Cortical 5-HT(2A) Receptor-mediated Signaling Pathways to Affect Behavior
  Neuron. Feb, 2007  |   Pubmed ID: 17270739
• Heterotrimeric G Proteins: Insights into the Neurobiology of Mood Disorders
  Current Neuropharmacology. Apr, 2006  |   Pubmed ID: 18615130
• P53 Mediates Nontranscriptional Cell Death in Dopaminergic Cells in Response to Proteasome Inhibition
  The Journal of Biological Chemistry. Dec, 2006  |   Pubmed ID: 17060322
• Cortical 5-HT2A Receptor Signaling Modulates Anxiety-like Behaviors in Mice
  Science (New York, N.Y.). Jul, 2006  |   Pubmed ID: 16873667
• Method for Multiplex Cellular Detection of MRNAs Using Quantum Dot Fluorescent in Situ Hybridization
  Nucleic Acids Research. 2005  |   Pubmed ID: 16224100
• Epsilon-sarcoglycan Immunoreactivity and MRNA Expression in Mouse Brain
  The Journal of Comparative Neurology. Jan, 2005  |   Pubmed ID: 15612018
• Agonist-induced Desensitization and Endocytosis of Heterodimeric GABAB Receptors in CHO-K1 Cells
  European Journal of Pharmacology. Nov, 2003  |   Pubmed ID: 14637170
• Transcriptome Fingerprints Distinguish Hallucinogenic and Nonhallucinogenic 5-hydroxytryptamine 2A Receptor Agonist Effects in Mouse Somatosensory Cortex
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Oct, 2003  |   Pubmed ID: 14523084
• Validated Genomic Approach to Study Differentially Expressed Genes in Complex Tissues
  Neurochemical Research. Oct, 2002  |   Pubmed ID: 12462402
• Quantitative Stoichiometry of G-proteins Activated by Mu-opioid Receptors in Postmortem Human Brain
  European Journal of Pharmacology. Sep, 2002  |   Pubmed ID: 12323382
• Effects of Age, Postmortem Delay and Storage Time on Receptor-mediated Activation of G-proteins in Human Brain
  Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. Apr, 2002  |   Pubmed ID: 11927171
• Distribution of Prolyl Endopeptidase Activities in Rat and Human Brain
  Neurochemistry International. Apr, 2002  |   Pubmed ID: 11792464