John S. Condeelis Cancer Dormancy and Tumor Microenvironment Institute Albert Einstein College of Medicine/Montefiore Medical Center Biography Publications Institution JoVE Articles John S. Condeelis has not added a biography. If you are John S. Condeelis and would like to personalize this page please email our Author Liaison for assistance. Publications Racial Disparity in Tumor Microenvironment and Distant Recurrence in Residual Breast Cancer After Neoadjuvant Chemotherapy NPJ Breast Cancer. Jun, 2023 | Pubmed ID: 37311792 Macrophages Promote Tumor Cell Extravasation Across an Endothelial Barrier Through Thin Membranous Connections Cancers. Mar, 2023 | Pubmed ID: 37046751 Cooperative NF-κB and Notch1 Signaling Promotes Macrophage-mediated MenaINV Expression in Breast Cancer Breast Cancer Research : BCR. Apr, 2023 | Pubmed ID: 37024946 Intravital Imaging to Study Cancer Progression and Metastasis Nature Reviews. Cancer. Jan, 2023 | Pubmed ID: 36385560 Interleukin 4 Controls the Pro-Tumoral Role of Macrophages in Mammary Cancer Pulmonary Metastasis in Mice Cancers. Sep, 2022 | Pubmed ID: 36077870 Assessment of MRI to Estimate Metastatic Dissemination Risk and Prometastatic Effects of Chemotherapy NPJ Breast Cancer. Sep, 2022 | Pubmed ID: 36056005 Racial Disparity in Distant Recurrence-free Survival in Patients with Localized Breast Cancer: A Pooled Analysis of National Surgical Adjuvant Breast and Bowel Project Trials Cancer. Jul, 2022 | Pubmed ID: 35578919 Combining TMEM Doorway Score and Mena Score Improves the Prediction of Distant Recurrence Risk in HR+/HER2- Breast Cancer Patients Cancers. Apr, 2022 | Pubmed ID: 35565297 Primary Tumor Associated Macrophages Activate Programs of Invasion and Dormancy in Disseminating Tumor Cells Nature Communications. Feb, 2022 | Pubmed ID: 35110548 Validation of an Automated Quantitative Digital Pathology Approach for Scoring TMEM, a Prognostic Biomarker for Metastasis Cancers. Mar, 2020 | Pubmed ID: 32244564 Black Race and Distant Recurrence After Neoadjuvant or Adjuvant Chemotherapy in Breast Cancer Clinical & Experimental Metastasis. 10, 2018 | Pubmed ID: 30136072 Signatures of Breast Cancer Metastasis at a Glance Journal of Cell Science. May, 2016 | Pubmed ID: 27084578 GPCR Signaling Mediates Tumor Metastasis Via PI3Kβ Cancer Research. May, 2016 | Pubmed ID: 27013201 3-D Individual Cell Based Computational Modeling of Tumor Cell-macrophage Paracrine Signaling Mediated by EGF and CSF-1 Gradients Integrative Biology : Quantitative Biosciences from Nano to Macro. Jan, 2016 | Pubmed ID: 26686751 Characterization of the Expression of the Pro-metastatic Mena(INV) Isoform During Breast Tumor Progression Clinical & Experimental Metastasis. Mar, 2016 | Pubmed ID: 26680363 PTP1B-dependent Regulation of Receptor Tyrosine Kinase Signaling by the Actin-binding Protein Mena Molecular Biology of the Cell. Nov, 2015 | Pubmed ID: 26337385 Real-Time Imaging Reveals Local, Transient Vascular Permeability, and Tumor Cell Intravasation Stimulated by TIE2hi Macrophage-Derived VEGFA Cancer Discovery. Sep, 2015 | Pubmed ID: 26269515 Menacalc, a Quantitative Method of Metastasis Assessment, As a Prognostic Marker for Axillary Node-negative Breast Cancer BMC Cancer. 2015 | Pubmed ID: 26112005 Invasive Breast Carcinoma Cells from Patients Exhibit MenaINV- and Macrophage-dependent Transendothelial Migration Science Signaling. Nov, 2014 | Pubmed ID: 25429076 An in Vitro One-dimensional Assay to Study Growth Factor-regulated Tumor Cell-macrophage Interaction Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 24908299 Metastatic Cells: Moving Onco-targets Oncotarget. Jun, 2014 | Pubmed ID: 24907202 Tumor Microenvironment of Metastasis and Risk of Distant Metastasis of Breast Cancer Journal of the National Cancer Institute. Aug, 2014 | Pubmed ID: 24895374 Invadopodia in Context Cell Adhesion & Migration. 2014 | Pubmed ID: 24713806 Spatial Regulation of Tumor Cell Protrusions by RhoC Cell Adhesion & Migration. 2014 | Pubmed ID: 24642482 Filamin A Interacting Protein 1-like Inhibits WNT Signaling and MMP Expression to Suppress Cancer Cell Invasion and Metastasis International Journal of Cancer. Jul, 2014 | Pubmed ID: 24327474 Intravital Multiphoton Imaging Reveals Multicellular Streaming As a Crucial Component of in Vivo Cell Migration in Human Breast Tumors Intravital. Apr, 2013 | Pubmed ID: 25013744 Wiskott-Aldrich Syndrome Protein Regulates Leukocyte-dependent Breast Cancer Metastasis Cell Reports. Aug, 2013 | Pubmed ID: 23911287 Dysregulation of PAD4-mediated Citrullination of Nuclear GSK3β Activates TGF-β Signaling and Induces Epithelial-to-mesenchymal Transition in Breast Cancer Cells Proceedings of the National Academy of Sciences of the United States of America. Jul, 2013 | Pubmed ID: 23818587 Development Path and Current Status of the NANIVID: a New Device for Cancer Cell Studies Journal of Micro/nanolithography, MEMS, and MOEMS : JM3. Mar, 2012 | Pubmed ID: 25419258 Reconstitution of in Vivo Macrophage-tumor Cell Pairing and Streaming Motility on One-dimensional Micro-patterned Substrates Intravital. Jul, 2012 | Pubmed ID: 24634804 Selective Gene-expression Profiling of Migratory Tumor Cells in Vivo Predicts Clinical Outcome in Breast Cancer Patients Breast Cancer Research : BCR. 2012 | Pubmed ID: 23113900 Quantitative Assessment of Invasive Mena Isoforms (Menacalc) As an Independent Prognostic Marker in Breast Cancer Breast Cancer Research : BCR. 2012 | Pubmed ID: 22971274 A FRET-facilitated Photoswitching Using an Orange Fluorescent Protein with the Fast Photoconversion Kinetics Journal of the American Chemical Society. Sep, 2012 | Pubmed ID: 22900938 Three-dimensional Microfluidic Model for Tumor Cell Intravasation and Endothelial Barrier Function Proceedings of the National Academy of Sciences of the United States of America. Aug, 2012 | Pubmed ID: 22869695 Korreliert Immunhistochemische Und Zytologischen Proben Für Die Vorhersage Der Hämatogene Verbreitung Von Brustkrebs The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Jan, 2012 | Pubmed ID: 22215635 Gegensätzlichen Rollen Von CXCR4 Und CXCR7 in Brust Krebsmetastase Breast Cancer Research : BCR. Dec, 2011 | Pubmed ID: 22152016 Ein EMT-gesteuerte Alternatives Spleißen Programm Tritt Im Menschlichen Brustkrebs Und Moduliert Zelluläre Phänotyp PLoS Genetics. Aug, 2011 | Pubmed ID: 21876675 Eine Photoswitchable-zu Weit-orangerot Fluoreszierenden Proteins, PSmOrange Nature Methods. Sep, 2011 | Pubmed ID: 21804536 Chemotaxis Bei Krebs Nature Reviews. Cancer. Aug, 2011 | Pubmed ID: 21779009 Mena Invasive (MenaINV) Fördert Die Vielzelligen Streaming Motilität Und Transendothelial Migration in Einem Mausmodell an Brustkrebs Journal of Cell Science. Jul, 2011 | Pubmed ID: 21670198 Mena Invasive (Mena(INV)) Und Mena11a Isoformen Spielen Unterschiedliche Rollen Im Brust-Krebs Zelle Zusammenhalt Und Zusammenarbeit Mit TMEM Clinical & Experimental Metastasis. Aug, 2011 | Pubmed ID: 21484349 Mena-Mangel Verzögert Tumor Fortschreiten Und Metastasierung in Polyoma Mitte-T Transgenen Maus Milch-Tumoren Verringert Breast Cancer Research : BCR. 2010 | Pubmed ID: 21108830 Ein Neues Chemotaxis-Gerät Für Zelle Migrationsforschung Integrative Biology : Quantitative Biosciences from Nano to Macro. Nov, 2010 | Pubmed ID: 20938544 AACR Sonderkonferenz Auf Epitheliale-Mesenchymale Transition Und Krebs Fortschreiten Und Behandlung Cancer Research. Oct, 2010 | Pubmed ID: 20823151 Genexpressionsanalyse Der Makrophagen, Die Erleichterung Der Tumorinvasion Unterstützt Eine Rolle Für Wnt-Signalisierung Bei Der Vermittlung Ihrer Aktivität in Primären Mamma-Tumoren Journal of Immunology (Baltimore, Md. : 1950). Jan, 2010 | Pubmed ID: 20018620 Invasion Von Menschlichen Brustkrebszellen In-vivo Erfordert Parakrine Und Autocrine Schleifen Mit Den Kolonie-stimulierende Faktor-1-Rezeptor Cancer Research. Dec, 2009 | Pubmed ID: 19934330 Differenzielle Verstärkung Der Brust Krebs Zelle Motilität Und Metastasierung Von Kegelrad Und Kinase-Domäne-Mutationen Der Klasse IA Phosphoinositid-3-Kinase Cancer Research. Dec, 2009 | Pubmed ID: 19903845 Tumor Mikromilieu Der Metastasierung in Menschlichen Mammakarzinom: Möglicher Prognostischer Marker Mit Hämatogene Verbreitung Verknüpft Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2009 | Pubmed ID: 19318480 Identifikation Der Invasion Bestimmte Splice Varianten Des Zytoskelett Proteins Mena in Milch-Tumorzellen Während Invasion In-vivo Clinical & Experimental Metastasis. 2009 | Pubmed ID: 18985426 Ein Mena-Invasion-Isoform Spurenelement EGF-induzierte Karzinom Invasion Und Metastasierung Developmental Cell. Dec, 2008 | Pubmed ID: 19081071 Mechanismen Und Zellulare Rollen Der Lokalen Proteinsynthese in Den Säugetier-Zellen Current Opinion in Cell Biology. Apr, 2008 | Pubmed ID: 18378131 RhoA/ROCK-vermittelte Umschalten Zwischen Cdc42 - Und Rac1-abhängigen Vorwölbung in MTLn3-Karzinom-Zellen Experimental Cell Research. Apr, 2008 | Pubmed ID: 18316075 Imaging in Echtzeit Genexpression in Lebenden Systemen Mit Einzel-Transcript Auflösung: Entwurf Und Imaging System-Setup Zu Erstellen CSH Protocols. 2007 | Pubmed ID: 21356986 Echtzeit-Genexpression in Lebenden Systemen Mit Single-Transcript Resolution Imaging: Einzelne MRNA Particle Tracking Mit ImageJ-basierte Analyse CSH Protocols. 2007 | Pubmed ID: 21356980 Imaging in Echtzeit Genexpression in Lebenden Systemen Mit Einzel-Transcript Auflösung: Bildanalyse Der Einzigen MRNA Transkripte CSH Protocols. 2007 | Pubmed ID: 21356979 Bildgebung in Echtzeit Genexpression in Der Lebenden Hefe CSH Protocols. 2007 | Pubmed ID: 21356978 Imaging in Echtzeit Genexpression in Den Säugetier-Zellen Mit Einzel-Transcript Auflösung CSH Protocols. 2007 | Pubmed ID: 21356977 EGF-induzierte PIP2 Hydrolyse Frei Und Aktiviert Cofilin Lokal in Karzinom-Zellen The Journal of Cell Biology. Dec, 2007 | Pubmed ID: 18086920 ZBP1 Verbessert Die Zellpolarität Und Reduziert Die Chemotaxis Journal of Cell Science. Sep, 2007 | Pubmed ID: 17878234 Cdc42 Ist Für EGF-stimuliert Körper Und Motilität in MTLn3-Karzinom-Zellen Erforderlich Journal of Cell Science. Oct, 2007 | Pubmed ID: 17855387 Die Unterschiedlichen Rollen Von Ras Und Rac in PI 3-Kinase-abhängigen Körper Während Der EGF-stimuliert Zellmigration Journal of Cell Science. Sep, 2007 | Pubmed ID: 17698922 Koordinierte Regulierung Der Wege Für Verstärkte Zelle Motilität Und Chemotaxis Ist in Ratte Und Maus Mamma-Tumoren Konserviert Cancer Research. Apr, 2007 | Pubmed ID: 17440055 Molekulares Klonen Von HMena (ENAH) Und Seine Spleißstelle Variant HMena + 11a: Epidermaler Wachstumsfaktor Erhöht Ihren Ausdruck Und Stimuliert HMena + 11a Phosphorylierung in Brust-Krebs-Zelllinien Cancer Research. Mar, 2007 | Pubmed ID: 17363586 ROCK - Und Myosin-abhängigen Matrix Verformung Ermöglicht Protease-unabhängige Tumor-Zell-Einmarsch In-vivo Current Biology : CB. Aug, 2006 | Pubmed ID: 16890527 Einleitung Von Cofilin Aktivität Als Reaktion Auf EGF Ist Abgekoppelt Von Cofilin Phosphorylierung Und Dephosphorylierung in Karzinom-Zellen Journal of Cell Science. Jul, 2006 | Pubmed ID: 16803871 Der Status Der Aktivität Von Cofilin Bezieht Sich Direkt Auf Invasion, Intravasation Und Metastasierung Von Mamma-Tumoren The Journal of Cell Biology. May, 2006 | Pubmed ID: 16651380 Makrophagen Fördert Die Invasion Von Brustkarzinomzellen über Einen Kolonie-stimulierenden Factor-1/epidermal Wachstumsfaktor Parakrine Schleife Cancer Research. Jun, 2005 | Pubmed ID: 15958574 Tumorzellen Auf Frischer Tat Ertappt Von Eindringenden: Ihre Strategie Für Eine Verstärkte Zell-Motilität Trends in Cell Biology. Mar, 2005 | Pubmed ID: 15752977 Identifizierung Und Prüfung Eines Gensignatur Der Invasiven Karzinom-Zellen in Primären Brusttumoren Cancer Research. Dec, 2004 | Pubmed ID: 15574765 Brustkrebs-Zellen Durch Chemotaxis Von Primären Tumoren Isoliert Wurden, Zeigen Erhöhte Überlebensrate Und Resistenz Gegenüber Chemotherapie Cancer Research. Nov, 2004 | Pubmed ID: 15520165 Die Überexpression Des P110beta Aber Nicht P110alpha Isoform Der PI-3-Kinase Hemmt Motilität in Brustkrebszellen Cell Motility and the Cytoskeleton. Nov, 2004 | Pubmed ID: 15468162 Cofilin Fördert Aktin-Polymerisation Und Definiert Die Richtung Der Zellbewegung Science (New York, N.Y.). Apr, 2004 | Pubmed ID: 15118165 Genexpressionsanalyse Auf Eine Kleine Anzahl Von Invasiven Zellen Durch Chemotaxis Von Primären Brusttumoren Der Maus Gesammelt BMC Biotechnology. Aug, 2003 | Pubmed ID: 12914671 GFP-Expression in Der Brustdrüse Zum Abbilden Von Mamma-Tumor-Zellen in Transgenen Mäusen Cancer Research. Dec, 2002 | Pubmed ID: 12499251 Einzel-Zell-Verhalten Bei Metastasiertem Primären Brusttumoren Mit Genexpressionsmuster Korreliert Offenbart Durch Molekulare Profiling Cancer Research. Nov, 2002 | Pubmed ID: 12414658 Eine Neue Strategie Für Käfighaltung Proteine durch Kinasen Reguliert Journal of the American Chemical Society. Mar, 2002 | Pubmed ID: 11890784 Decoding Metastasis-to-Metastasis Seeding Using a New In Vivo Technique for Tracking Breast Cancer Spread (Video) | JoVE Madeline Friedman-DeLuca1,2, Prachiben P. Patel1,2, Burcu Karadal-Ferrena1,2, Nicole D. Barth1,2, Camille L. Duran1,2, Xianjun Ye1,2,3, Michael Papanicolaou2,4, John S. Condeelis2,3,4,5,6,7, Maja H. Oktay1,2,3,5,6,7, Lucia Borriello*1,2,8, David Entenberg*1,2,3,5,6 1Department of Pathology, Albert Einstein College of Medicine/Montefiore Medical Center, 2Cancer Dormancy and Tumor Microenvironment Institute, Albert Einstein College of Medicine/Montefiore Medical Center, 3Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine/Montefiore Medical Center, 4Department of Cell Biology, Albert Einstein College of Medicine/Montefiore Medical Center, 5Montefiore Einstein Cancer Center, Albert Einstein College of Medicine/Montefiore Medical Center, 6Integrated Imaging Program for Cancer Research, Albert Einstein College of Medicine/Montefiore Medical Center, 7Department of Surgery, Albert Einstein College of Medicine/Montefiore Medical Center, 8Department of Cancer and Cellular Biology, Lewis Katz School of Medicine, Fox Chase Cancer Center JoVE 65732 Cancer Research Langfristige High-Resolution Intravitalmikroskopie in der Lunge mit einem Vakuum-Stabilisierte Imaging-Fenster Carolina Rodriguez-Tirado1, Takanori Kitamura5, Yu Kato1,2, Jeffery W. Pollard1,2,5, John S. Condeelis3,4, David Entenberg3,4 1Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 2Department of Obstetrics/Gynecology and Woman’s Health, Albert Einstein College of Medicine, 3Department of Anatomy & Structural Biology, Albert Einstein College of Medicine, 4Gruss-Lipper Biophotonics Center Integrated Imaging Program, Albert Einstein College of Medicine, 5Medical Research Council Centre for Reproductive Health, Queen’s Medical Research Institute, University of Edinburgh Cancer Research Erweiterte Zeitraffer-Intravital Imaging von Echtzeit-Vielzellige Dynamics im Tumormikromilieu Allison S. Harney1,2,3,4, Yarong Wang1,3, John S. Condeelis1,3,4, David Entenberg1,3,4 1Department of Anatomy & Structural Biology, Albert Einstein College of Medicine, 2Department of Radiology, Albert Einstein College of Medicine, 3Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, 4Integrated Imaging Program, Albert Einstein College of Medicine JoVE 54042 Medicine
Decoding Metastasis-to-Metastasis Seeding Using a New In Vivo Technique for Tracking Breast Cancer Spread (Video) | JoVE Madeline Friedman-DeLuca1,2, Prachiben P. Patel1,2, Burcu Karadal-Ferrena1,2, Nicole D. Barth1,2, Camille L. Duran1,2, Xianjun Ye1,2,3, Michael Papanicolaou2,4, John S. Condeelis2,3,4,5,6,7, Maja H. Oktay1,2,3,5,6,7, Lucia Borriello*1,2,8, David Entenberg*1,2,3,5,6 1Department of Pathology, Albert Einstein College of Medicine/Montefiore Medical Center, 2Cancer Dormancy and Tumor Microenvironment Institute, Albert Einstein College of Medicine/Montefiore Medical Center, 3Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine/Montefiore Medical Center, 4Department of Cell Biology, Albert Einstein College of Medicine/Montefiore Medical Center, 5Montefiore Einstein Cancer Center, Albert Einstein College of Medicine/Montefiore Medical Center, 6Integrated Imaging Program for Cancer Research, Albert Einstein College of Medicine/Montefiore Medical Center, 7Department of Surgery, Albert Einstein College of Medicine/Montefiore Medical Center, 8Department of Cancer and Cellular Biology, Lewis Katz School of Medicine, Fox Chase Cancer Center JoVE 65732 Cancer Research
Langfristige High-Resolution Intravitalmikroskopie in der Lunge mit einem Vakuum-Stabilisierte Imaging-Fenster Carolina Rodriguez-Tirado1, Takanori Kitamura5, Yu Kato1,2, Jeffery W. Pollard1,2,5, John S. Condeelis3,4, David Entenberg3,4 1Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, 2Department of Obstetrics/Gynecology and Woman’s Health, Albert Einstein College of Medicine, 3Department of Anatomy & Structural Biology, Albert Einstein College of Medicine, 4Gruss-Lipper Biophotonics Center Integrated Imaging Program, Albert Einstein College of Medicine, 5Medical Research Council Centre for Reproductive Health, Queen’s Medical Research Institute, University of Edinburgh Cancer Research
Erweiterte Zeitraffer-Intravital Imaging von Echtzeit-Vielzellige Dynamics im Tumormikromilieu Allison S. Harney1,2,3,4, Yarong Wang1,3, John S. Condeelis1,3,4, David Entenberg1,3,4 1Department of Anatomy & Structural Biology, Albert Einstein College of Medicine, 2Department of Radiology, Albert Einstein College of Medicine, 3Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, 4Integrated Imaging Program, Albert Einstein College of Medicine JoVE 54042 Medicine