Jonathan A. R. Worrall

Publications

• Iron Oxidation in Escherichia Coli Bacterioferritin Ferroxidase Centre, a Site Designed to React Rapidly with H2O2 but Slowly with O2
  Angewandte Chemie (International Ed. in English). Jan, 2021  |   Pubmed ID: 33482043
• Using Cryo-EM to Understand Antimycobacterial Resistance in the Catalase-peroxidase (KatG) from Mycobacterium Tuberculosis
  Structure (London, England : 1993). Jan, 2021  |   Pubmed ID: 33444527
• Serial Femtosecond Zero Dose Crystallography Captures a Water-Free Distal Heme Site in a Dye-Decolorising Peroxidase to Reveal a Catalytic Role for an Arginine in Fe =O Formation
  Angewandte Chemie (International Ed. in English). 11, 2020  |   Pubmed ID: 32780931
• A Subtle Structural Change in the Distal Haem Pocket Has a Remarkable Effect on Tuning Hydrogen Peroxide Reactivity in Dye Decolourising Peroxidases from Streptomyces Lividans
  Dalton Transactions (Cambridge, England : 2003). Feb, 2020  |   Pubmed ID: 31942590
• Comparison of the Structural Dynamic and Mitochondrial Electron-transfer Properties of the Proapoptotic Human Cytochrome C Variants, G41S, Y48H and A51V
  Journal of Inorganic Biochemistry. 02, 2020  |   Pubmed ID: 31760234
• Successful Sample Preparation for Serial Crystallography Experiments
  Journal of Applied Crystallography. Dec, 2019  |   Pubmed ID: 31798361
• High-throughput Structures of Protein-ligand Complexes at Room Temperature Using Serial Femtosecond Crystallography
  IUCrJ. Nov, 2019  |   Pubmed ID: 31709063
• Dose-resolved Serial Synchrotron and XFEL Structures of Radiation-sensitive Metalloproteins
  IUCrJ. Jul, 2019  |   Pubmed ID: 31316799
• A Histidine Residue and a Tetranuclear Cuprous-thiolate Cluster Dominate the Copper Loading Landscape of a Copper Storage Protein from Streptomyces Lividans
  Chemistry (Weinheim an Der Bergstrasse, Germany). Aug, 2019  |   Pubmed ID: 31111982
• An Aromatic Dyad Motif in Dye Decolourising Peroxidases Has Implications for Free Radical Formation and Catalysis
  Chemistry (Weinheim an Der Bergstrasse, Germany). Apr, 2019  |   Pubmed ID: 30945782
• Naturally Occurring Disease-Related Mutations in the 40-57 Ω-Loop of Human Cytochrome C Control Triggering of the Alkaline Isomerization
  Biochemistry. 07, 2018  |   Pubmed ID: 29949346
• A Cytosolic Copper Storage Protein Provides a Second Level of Copper Tolerance in Streptomyces Lividans
  Metallomics : Integrated Biometal Science. 01, 2018  |   Pubmed ID: 29292456
• Heightened Dynamics of the Oxidized Y48H Variant of Human Cytochrome C Increases Its Peroxidatic Activity
  Biochemistry. 11, 2017  |   Pubmed ID: 29083920
• Kinetic Characterisation of a Dye Decolourising Peroxidase from Streptomyces Lividans: New Insight into the Mechanism of Anthraquinone Dye Decolourisation
  Dalton Transactions (Cambridge, England : 2003). Jul, 2017  |   Pubmed ID: 28695933
• Photoreduction and Validation of Haem-ligand Intermediate States in Protein Crystals by Single-crystal Spectroscopy and Diffraction
  IUCrJ. May, 2017  |   Pubmed ID: 28512573
• Tyrosine or Tryptophan? Modifying a Metalloradical Catalytic Site by Removal of the Cys-Tyr Cross-Link in the Galactose 6-Oxidase Homologue GlxA
  Angewandte Chemie (International Ed. in English). 06, 2017  |   Pubmed ID: 28464409
• Near-complete Backbone Resonance Assignments of Acid-denatured Human Cytochrome C in Dimethylsulfoxide: a Prelude to Studying Interactions with Phospholipids
  Biomolecular NMR Assignments. Oct, 2017  |   Pubmed ID: 28260216
• Active-site Maturation and Activity of the Copper-radical Oxidase GlxA Are Governed by a Tryptophan Residue
  The Biochemical Journal. 02, 2017  |   Pubmed ID: 28093470
• Increased Dynamics in the 40-57 Ω-loop of the G41S Variant of Human Cytochrome C Promote Its Pro-apoptotic Conformation
  Scientific Reports. Jul, 2016  |   Pubmed ID: 27461282
• Heterogeneity in the Histidine-brace Copper Coordination Sphere in Auxiliary Activity Family 10 (AA10) Lytic Polysaccharide Monooxygenases
  The Journal of Biological Chemistry. Jun, 2016  |   Pubmed ID: 27129229
• The DyP-type Peroxidase DtpA is a Tat-substrate Required for GlxA Maturation and Morphogenesis in Streptomyces
  Open Biology. Jan, 2016  |   Pubmed ID: 26740586
• Copper and Nickel Bind Via Two Distinct Kinetic Mechanisms to a CsoR Metalloregulator
  Dalton Transactions (Cambridge, England : 2003). Dec, 2015  |   Pubmed ID: 26536457
• Structural Insights into Conformational Switching in the Copper Metalloregulator CsoR from Streptomyces Lividans
  Acta Crystallographica. Section D, Biological Crystallography. Sep, 2015  |   Pubmed ID: 26327377
• GlxA is a New Structural Member of the Radical Copper Oxidase Family and is Required for Glycan Deposition at Hyphal Tips and Morphogenesis of Streptomyces Lividans
  The Biochemical Journal. Aug, 2015  |   Pubmed ID: 26205496
• Backbone Resonance Assignments of Ferric Human Cytochrome C and the Pro-apoptotic G41S Mutant in the Ferric and Ferrous States
  Biomolecular NMR Assignments. Oct, 2015  |   Pubmed ID: 26123826
• Copper Trafficking in the CsoR Regulon of Streptomyces Lividans
  Metallomics : Integrated Biometal Science. Jan, 2015  |   Pubmed ID: 25409712
• Structural and Mechanistic Insights into an Extracytoplasmic Copper Trafficking Pathway in Streptomyces Lividans
  The Biochemical Journal. May, 2014  |   Pubmed ID: 24548299
• Conformational and Thermodynamic Hallmarks of DNA Operator Site Specificity in the Copper Sensitive Operon Repressor from Streptomyces Lividans
  Nucleic Acids Research. Jan, 2014  |   Pubmed ID: 24121681
• The Hydrogen-peroxide-induced Radical Behaviour in Human Cytochrome C-phospholipid Complexes: Implications for the Enhanced Pro-apoptotic Activity of the G41S Mutant
  The Biochemical Journal. Dec, 2013  |   Pubmed ID: 24099549
• The Role of the Cys-X-X-X-Cys Motif on the Kinetics of Cupric Ion Loading to the Streptomyces Lividans Sco Protein
  Dalton Transactions (Cambridge, England : 2003). Aug, 2013  |   Pubmed ID: 23759834
• Morphological Development and Cytochrome C Oxidase Activity in Streptomyces Lividans Are Dependent on the Action of a Copper Bound Sco Protein
  Open Biology. Jan, 2013  |   Pubmed ID: 23345541
• Risposta a Stress in Streptomyces Lividans Di Rame Si Estende Oltre Geni Sotto Il Controllo Diretto Di Una Proteina Repressore Operone Rame-sensibili (CsoR)
  The Journal of Biological Chemistry. May, 2012  |   Pubmed ID: 22451651
• Ferric Haem Forms of Mycobacterium Tuberculosis Catalase-peroxidase Probed by EPR Spectroscopy: Their Stability and Interplay with PH
  Biochimie. Jun, 2012  |   Pubmed ID: 22381358
• An Investigation into a Cardiolipin Acyl Chain Insertion Site in Cytochrome C
  Biochimica Et Biophysica Acta. May, 2012  |   Pubmed ID: 22365930
• The Role of a Disulfide Bridge in the Stability and Folding Kinetics of Arabidopsis Thaliana Cytochrome C(6A)
  Biochimica Et Biophysica Acta. Feb, 2012  |   Pubmed ID: 22085909
• Structural and Kinetic Studies of Imidazole Binding to Two Members of the Cytochrome C (6) Family Reveal an Important Role for a Conserved Heme Pocket Residue
  Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry. Apr, 2011  |   Pubmed ID: 21267610
• Thermodynamic Analysis of Jun-Fos Coiled Coil Peptide Antagonists
  The FEBS Journal. Feb, 2011  |   Pubmed ID: 21199371
• Copper Mining in Streptomyces: Enzymes, Natural Products and Development
  Natural Product Reports. May, 2010  |   Pubmed ID: 20372697
• Cytochrome C6A: Discovery, Structure and Properties Responsible for Its Low Haem Redox Potential
  Biochemical Society Transactions. Dec, 2008  |   Pubmed ID: 19021519