K. Peter R. Nilsson IFM-Department of Chemistry Linköping University Biography Publications Institution JoVE Articles K. Peter R. Nilsson has not added a biography. If you are K. Peter R. Nilsson and would like to personalize this page please email our Author Liaison for assistance. Publications Islet Amyloid Deposits Preferentially in the Highly Functional and Most Blood-perfused Islets Endocrine Connections. Oct, 2017 | Pubmed ID: 28790139 Non-fused Phospholes As Fluorescent Probes for Imaging of Lipid Droplets in Living Cells Frontiers in Chemistry. 2017 | Pubmed ID: 28487854 Seed-dependent Templating of Murine AA Amyloidosis Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. Mar, 2017 | Pubmed ID: 28434369 Establishing and Validating the Fluorescent Amyloid Ligand H-FTAA (heptamer Formyl Thiophene Acetic Acid) to Identify Transthyretin Amyloid Deposits in Carpal Tunnel Syndrome Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. Jun, 2017 | Pubmed ID: 28434259 Specific Imaging of Intracellular Lipid Droplets Using a Benzothiadiazole Derivative with Solvatochromic Properties Bioconjugate Chemistry. May, 2017 | Pubmed ID: 28402621 Post-translational Modifications in PrP Expand the Conformational Diversity of Prions in Vivo Scientific Reports. Mar, 2017 | Pubmed ID: 28272426 In Vivo Polymerization and Manufacturing of Wires and Supercapacitors in Plants Proceedings of the National Academy of Sciences of the United States of America. Mar, 2017 | Pubmed ID: 28242683 Labeling Nanoparticles: Dye Leakage and Altered Cellular Uptake Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Aug, 2017 | Pubmed ID: 27077940 Real-time Optotracing of Curli and Cellulose in Live Salmonella Biofilms Using Luminescent Oligothiophenes NPJ Biofilms and Microbiomes. 2016 | Pubmed ID: 28721253 Nanoscale Structure and Spectroscopic Probing of Aβ1-40 Fibril Bundle Formation Frontiers in Chemistry. 2016 | Pubmed ID: 27921029 De Novo Design of a Biologically Active Amyloid Science (New York, N.Y.). 11, 2016 | Pubmed ID: 27846578 Anionic Oligothiophenes Compete for Binding of X-34 but Not PIB to Recombinant Aβ Amyloid Fibrils and Alzheimer's Disease Brain-Derived Aβ Chemistry (Weinheim an Der Bergstrasse, Germany). Dec, 2016 | Pubmed ID: 27767229 Nondestructive, Real-time Determination and Visualization of Cellulose, Hemicellulose and Lignin by Luminescent Oligothiophenes Scientific Reports. Oct, 2016 | Pubmed ID: 27759105 Conversion of Synthetic Aβ to In Vivo Active Seeds and Amyloid Plaque Formation in a Hippocampal Slice Culture Model The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2016 | Pubmed ID: 27147660 (11)C and (18)F Radiolabeling of Tetra- and Pentathiophenes As PET-Ligands for Amyloid Protein Aggregates ACS Medicinal Chemistry Letters. Apr, 2016 | Pubmed ID: 27096043 Establishing the Fluorescent Amyloid Ligand H-FTAA for Studying Human Tissues with Systemic and Localized Amyloid Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. Jun, 2016 | Pubmed ID: 26987044 Protein Aggregation As an Antibiotic Design Strategy Molecular Microbiology. Mar, 2016 | Pubmed ID: 26559925 An Imidazole Functionalized Pentameric Thiophene Displays Different Staining Patterns in Normal and Malignant Cells Frontiers in Chemistry. 2015 | Pubmed ID: 26501054 A Palette of Fluorescent Thiophene-Based Ligands for the Identification of Protein Aggregates Chemistry (Weinheim an Der Bergstrasse, Germany). Oct, 2015 | Pubmed ID: 26388448 Pathological, Biochemical, and Biophysical Characteristics of the Transthyretin Variant Y114H (p.Y134H) Explain Its Very Mild Clinical Phenotype Journal of the Peripheral Nervous System : JPNS. Dec, 2015 | Pubmed ID: 26306725 Structure-based Drug Design Identifies Polythiophenes As Antiprion Compounds Science Translational Medicine. Aug, 2015 | Pubmed ID: 26246168 The Fluorescent Pentameric Oligothiophene PFTAA Identifies Filamentous Tau in Live Neurons Cultured from Adult P301S Tau Mice Frontiers in Neuroscience. 2015 | Pubmed ID: 26074756 Distinct Spacing Between Anionic Groups: An Essential Chemical Determinant for Achieving Thiophene-Based Ligands to Distinguish β-Amyloid or Tau Polymorphic Aggregates Chemistry (Weinheim an Der Bergstrasse, Germany). Jun, 2015 | Pubmed ID: 26013403 Endogenous Murine Aβ Increases Amyloid Deposition in APP23 but Not in APPPS1 Transgenic Mice Neurobiology of Aging. Jul, 2015 | Pubmed ID: 25911278 Sensitive and Rapid Assessment of Amyloid by Oligothiophene Fluorescence in Subcutaneous Fat Tissue Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. Mar, 2015 | Pubmed ID: 25847117 Differential Vital Staining of Normal Fibroblasts and Melanoma Cells by an Anionic Conjugated Polyelectrolyte Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Mar, 2015 | Pubmed ID: 25605326 An Azide Functionalized Oligothiophene Ligand--a Versatile Tool for Multimodal Detection of Disease Associated Protein Aggregates Biosensors & Bioelectronics. Jan, 2015 | Pubmed ID: 25089818 Multimodal Fluorescence Microscopy of Prion Strain Specific PrP Deposits Stained by Thiophene-based Amyloid Ligands Prion. 2014 | Pubmed ID: 25495506 Toward a Molecular Understanding of the Detection of Amyloid Proteins with Flexible Conjugated Oligothiophenes The Journal of Physical Chemistry. A. Oct, 2014 | Pubmed ID: 25247879 Aβ Seeds Resist Inactivation by Formaldehyde Acta Neuropathologica. Oct, 2014 | Pubmed ID: 25193240 Pentameric Thiophene-based Ligands That Spectrally Discriminate Amyloid-β and Tau Aggregates Display Distinct Solvatochromism and Viscosity-induced Spectral Shifts Chemistry (Weinheim an Der Bergstrasse, Germany). Sep, 2014 | Pubmed ID: 25111601 Direct Visualization of HIV-enhancing Endogenous Amyloid Fibrils in Human Semen Nature Communications. Apr, 2014 | Pubmed ID: 24691351 Cell Type Related Differences in Staining with Pentameric Thiophene Derivatives Cytometry. Part A : the Journal of the International Society for Analytical Cytology. Jul, 2014 | Pubmed ID: 24500794 Seeded Strain-like Transmission of β-amyloid Morphotypes in APP Transgenic Mice EMBO Reports. Nov, 2013 | Pubmed ID: 23999102 The Structural Basis for Optimal Performance of Oligothiophene-based Fluorescent Amyloid Ligands: Conformational Flexibility is Essential for Spectral Assignment of a Diversity of Protein Aggregates Chemistry (Weinheim an Der Bergstrasse, Germany). Jul, 2013 | Pubmed ID: 23780508 Defining the Conformational Features of Anchorless, Poorly Neuroinvasive Prions PLoS Pathogens. 2013 | Pubmed ID: 23637596 Superresolution Imaging of Amyloid Fibrils with Binding-activated Probes ACS Chemical Neuroscience. Jul, 2013 | Pubmed ID: 23594172 Evidence for Age-dependent in Vivo Conformational Rearrangement Within Aβ Amyloid Deposits ACS Chemical Biology. 2013 | Pubmed ID: 23521783 Enhanced Fluorescent Assignment of Protein Aggregates by an Oligothiophene-porphyrin-based Amyloid Ligand Macromolecular Rapid Communications. May, 2013 | Pubmed ID: 23468206 Luminescent Conjugated Oligothiophenes for Sensitive Fluorescent Assignment of Protein Inclusion Bodies Chembiochem : a European Journal of Chemical Biology. Mar, 2013 | Pubmed ID: 23450708 Localization of Cholesterol, Amyloid and Glia in Alzheimer's Disease Transgenic Mouse Brain Tissue Using Time-of-flight Secondary Ion Mass Spectrometry (ToF-SIMS) and Immunofluorescence Imaging Acta Neuropathologica. Jan, 2013 | Pubmed ID: 22996963 Spectral Discrimination of Cerebral Amyloid Lesions After Peripheral Application of Luminescent Conjugated Oligothiophenes The American Journal of Pathology. Dec, 2012 | Pubmed ID: 23041059 Luminescent Conjugated Poly- and Oligo-thiophenes: Optical Ligands for Spectral Assignment of a Plethora of Protein Aggregates Biochemical Society Transactions. Aug, 2012 | Pubmed ID: 22817720 Multiple Substitutions of Methionine 129 in Human Prion Protein Reveal Its Importance in the Amyloid Fibrillation Pathway The Journal of Biological Chemistry. Jul, 2012 | Pubmed ID: 22669942 Derivatization of a Bioorthogonal Protected Trisaccharide Linker-toward Multimodal Tools for Chemical Biology Bioconjugate Chemistry. Jun, 2012 | Pubmed ID: 22568531 A Pentameric Luminescent-conjugated Oligothiophene for Optical Imaging of in Vitro-formed Amyloid Fibrils and Protein Aggregates in Tissue Sections Methods in Molecular Biology (Clifton, N.J.). 2012 | Pubmed ID: 22528107 Polythiophenes Inhibit Prion Propagation by Stabilizing Prion Protein (PrP) Aggregates The Journal of Biological Chemistry. Jun, 2012 | Pubmed ID: 22493452 Structure of the β2-α2 Loop and Interspecies Prion Transmission FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jul, 2012 | Pubmed ID: 22490928 Identification of Distinct Physiochemical Properties of Toxic Prefibrillar Species Formed by Aβ Peptide Variants Biochemical and Biophysical Research Communications. Apr, 2012 | Pubmed ID: 22475489 Nanoscopic and Photonic Ultrastructural Characterization of Two Distinct Insulin Amyloid States International Journal of Molecular Sciences. 2012 | Pubmed ID: 22408402 Curcumin Promotes A-beta Fibrillation and Reduces Neurotoxicity in Transgenic Drosophila PloS One. 2012 | Pubmed ID: 22348084 Cell Interaction Study of Amyloid by Using Luminescent Conjugated Polythiophene: Implication That Amyloid Cytotoxicity is Correlated with Prolonged Cellular Binding Chembiochem : a European Journal of Chemical Biology. Feb, 2012 | Pubmed ID: 22262644 Synthesis of a Library of Oligothiophenes and Their Utilization As Fluorescent Ligands for Spectral Assignment of Protein Aggregates Organic & Biomolecular Chemistry. Dec, 2011 | Pubmed ID: 22051883 Spongiform Encephalopathy in Transgenic Mice Expressing a Point Mutation in the β2-α2 Loop of the Prion Protein The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2011 | Pubmed ID: 21957246 Cross β-sheet Conformation of Keratin 8 is a Specific Feature of Mallory-Denk Bodies Compared with Other Hepatocyte Inclusions Gastroenterology. Sep, 2011 | Pubmed ID: 21699779 Drosophila Melanogaster As a Model System for Studies of Islet Amyloid Polypeptide Aggregation PloS One. 2011 | Pubmed ID: 21695120 Tracking Protein Aggregate Interactions Prion. Apr-Jun, 2011 | Pubmed ID: 21597336 Observations in APP Bitransgenic Mice Suggest That Diffuse and Compact Plaques Form Via Independent Processes in Alzheimer's Disease The American Journal of Pathology. May, 2011 | Pubmed ID: 21514441 Conjugated Polymers for Enhanced Bioimaging Biochimica Et Biophysica Acta. Mar, 2011 | Pubmed ID: 20471455 Prion Strain Interactions Are Highly Selective The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Sep, 2010 | Pubmed ID: 20826672 Spatially Controlled Amyloid Reactions Using Organic Electronics Small (Weinheim an Der Bergstrasse, Germany). Oct, 2010 | Pubmed ID: 20814927 A Fluorescent Pentameric Thiophene Derivative Detects in Vitro-formed Prefibrillar Protein Aggregates Biochemistry. Aug, 2010 | Pubmed ID: 20604540 Two Amyloid States of the Prion Protein Display Significantly Different Folding Patterns Journal of Molecular Biology. Jul, 2010 | Pubmed ID: 20553730 A Molecular Switch Controls Interspecies Prion Disease Transmission in Mice The Journal of Clinical Investigation. Jul, 2010 | Pubmed ID: 20551516 Efficient Imaging of Amyloid Deposits in Drosophila Models of Human Amyloidoses Nature Protocols. May, 2010 | Pubmed ID: 20431539 Structural Typing of Systemic Amyloidoses by Luminescent-conjugated Polymer Spectroscopy The American Journal of Pathology. Feb, 2010 | Pubmed ID: 20035056 Amyloid Fibrils of Human Prion Protein Are Spun and Woven from Morphologically Disordered Aggregates Prion. Oct-Dec, 2009 | Pubmed ID: 19923901 Fluorescent Oligo and Poly-thiophenes and Their Utilization for Recording Biological Events of Diverse Origin-when Organic Chemistry Meets Biology Journal of Chemical Biology. Nov, 2009 | Pubmed ID: 19649670 Novel Pentameric Thiophene Derivatives for in Vitro and in Vivo Optical Imaging of a Plethora of Protein Aggregates in Cerebral Amyloidoses ACS Chemical Biology. Aug, 2009 | Pubmed ID: 19624097 Functional Amyloids As Natural Storage of Peptide Hormones in Pituitary Secretory Granules Science (New York, N.Y.). Jul, 2009 | Pubmed ID: 19541956 Small Organic Probes As Amyloid Specific Ligands--past and Recent Molecular Scaffolds FEBS Letters. Aug, 2009 | Pubmed ID: 19376114 De Novo Generation of a Transmissible Spongiform Encephalopathy by Mouse Transgenesis Proceedings of the National Academy of Sciences of the United States of America. Jan, 2009 | Pubmed ID: 19073920 A Highly Insoluble State of Abeta Similar to That of Alzheimer's Disease Brain is Found in Arctic APP Transgenic Mice Neurobiology of Aging. Sep, 2009 | Pubmed ID: 18192084 Prion Strain Discrimination Using Luminescent Conjugated Polymers Nature Methods. Dec, 2007 | Pubmed ID: 18026110 Studies of Luminescent Conjugated Polythiophene Derivatives: Enhanced Spectral Discrimination of Protein Conformational States Bioconjugate Chemistry. Nov-Dec, 2007 | Pubmed ID: 17939727 Imaging Distinct Conformational States of Amyloid-beta Fibrils in Alzheimer's Disease Using Novel Luminescent Probes ACS Chemical Biology. Aug, 2007 | Pubmed ID: 17672509 Conjugated Polyelectrolytes--conformation-sensitive Optical Probes for Staining and Characterization of Amyloid Deposits Chembiochem : a European Journal of Chemical Biology. Jul, 2006 | Pubmed ID: 16729336 Surface Energy Modified Chips for Detection of Conformational States and Enzymatic Activity in Biomolecules Langmuir : the ACS Journal of Surfaces and Colloids. Feb, 2006 | Pubmed ID: 16489808 Solution Structure of Chi-conopeptide MrIA, a Modulator of the Human Norepinephrine Transporter Biopolymers. 2005 | Pubmed ID: 15931669 Conjugated Polyelectrolytes: Conformation-sensitive Optical Probes for Detection of Amyloid Fibril Formation Biochemistry. Mar, 2005 | Pubmed ID: 15751948 Synthesis of a Regioregular Zwitterionic Conjugated Oligoelectrolyte, Usable As an Optical Probe for Detection of Amyloid Fibril Formation at Acidic PH Journal of the American Chemical Society. Feb, 2005 | Pubmed ID: 15713111 Twisting Macromolecular Chains: Self-assembly of a Chiral Supermolecule from Nonchiral Polythiophene Polyanions and Random-coil Synthetic Peptides Proceedings of the National Academy of Sciences of the United States of America. Aug, 2004 | Pubmed ID: 15280547 Self-assembly of Synthetic Peptides Control Conformation and Optical Properties of a Zwitterionic Polythiophene Derivative Proceedings of the National Academy of Sciences of the United States of America. Sep, 2003 | Pubmed ID: 12928490 Chip and Solution Detection of DNA Hybridization Using a Luminescent Zwitterionic Polythiophene Derivative Nature Materials. Jun, 2003 | Pubmed ID: 12754497 تصوير الأنسجة اميلويد ملطخة بالانارة أوليجوثيوفينيس مترافق بالفائقة الطيفية [كنفوكل] مجهرية والأسفار تصوير مدى الحياة Sofie Nyström1, Marcus Bäck1, K. Peter R. Nilsson1, Per Hammarström1 1IFM-Department of Chemistry, Linköping University JoVE 56279 Biochemistry
تصوير الأنسجة اميلويد ملطخة بالانارة أوليجوثيوفينيس مترافق بالفائقة الطيفية [كنفوكل] مجهرية والأسفار تصوير مدى الحياة Sofie Nyström1, Marcus Bäck1, K. Peter R. Nilsson1, Per Hammarström1 1IFM-Department of Chemistry, Linköping University JoVE 56279 Biochemistry