Kai Xiao Precision Medicine Research Center, Sichuan Provincial Key Laboratory of Precision Medicine, National Clinical Research Center for Geriatrics, West China Hospital Sichuan University Biography Publications Institution JoVE Articles Kai Xiao has not added a biography. If you are Kai Xiao and would like to personalize this page please email our Author Liaison for assistance. Publications Mitochondria-Targeting and Multiresponsive Nanoplatform Based on AIEgens for Synergistic Chemo-Photodynamic Therapy and Enhanced Immunotherapy Biomacromolecules. Feb, 2023 | Pubmed ID: 36703538 Nanoparticle-Mediated Delivery of STAT3 Inhibitors in the Treatment of Lung Cancer Pharmaceutics. Dec, 2022 | Pubmed ID: 36559280 Acquired Semi-squamatization During Chemotherapy Suggests Differentiation As a Therapeutic Strategy for Bladder Cancer Cancer Cell. Sep, 2022 | Pubmed ID: 36099882 Nanoparticles-Based Strategies to Improve the Delivery of Therapeutic Small Interfering RNA in Precision Oncology Pharmaceutics. Jul, 2022 | Pubmed ID: 36015212 SKLB-14b, a Novel Oral Microtubule-destabilizing Agent Based on Hydroxamic Acid with Potent Anti-tumor and Anti-multidrug Resistance Activities Bioorganic Chemistry. Nov, 2022 | Pubmed ID: 35964504 Synergistic Catalysis Between a Dipeptide Phosphonium Salt and a Metal-Based Lewis Acid for Asymmetric Synthesis of N-Bridged [3.2.1] Ring Systems Angewandte Chemie (International Ed. in English). Sep, 2022 | Pubmed ID: 35766480 Targeted Drug/Gene/Photodynamic Therapy Via a Stimuli-Responsive Dendritic-Polymer-Based Nanococktail for Treatment of EGFR-TKI-Resistant Non-Small-Cell Lung Cancer Advanced Materials (Deerfield Beach, Fla.). Jul, 2022 | Pubmed ID: 35481881 Asymmetric Synthesis of N-bridged [3.3.1] Ring Systems by Phosphonium Salt/Lewis Acid Relay Catalysis Nature Communications. Jan, 2022 | Pubmed ID: 35042870 Targeted Delivery by PH-responsive MPEG-S-PBLG Micelles Significantly Enhances the Anti-tumor Efficacy of Doxorubicin with Reduced Cardiotoxicity Drug Delivery. Dec, 2021 | Pubmed ID: 34842005 Prescription of Relieved Goiter Through Promoted Apoptosis of Thyroid Cells Via MiR-511-3p and PTEN/PI3K/Akt Pathway Journal of Healthcare Engineering. 2021 | Pubmed ID: 34630982 Edaravone Combined with Dexamethasone Exhibits Synergic Effects on Attenuating Smoke-induced Inhalation Lung Injury in Rats Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. Sep, 2021 | Pubmed ID: 34225014 Regio- and Stereoselective Cascade of β,γ-Unsaturated Ketones by Dipeptided Phosphonium Salt Catalysis: Stereospecific Construction of Dihydrofuro-Fused [2,3-b] Skeletons Angewandte Chemie (International Ed. in English). Sep, 2021 | Pubmed ID: 34213051 Patient-derived Non-small Cell Lung Cancer Xenograft Mirrors Complex Tumor Heterogeneity Cancer Biology & Medicine. Feb, 2021 | Pubmed ID: 33628593 LHRH-Targeted Redox-Responsive Crosslinked Micelles Impart Selective Drug Delivery and Effective Chemotherapy in Triple-Negative Breast Cancer Advanced Healthcare Materials. 02, 2021 | Pubmed ID: 33200571 PH-Responsive Hyperbranched Polypeptides Based on Schiff Bases As Drug Carriers for Reducing Toxicity of Chemotherapy RSC Advances. Apr, 2020 | Pubmed ID: 35492972 The Effects of Gold Nanoparticles on Leydig Cells and Male Reproductive Function in Mice International Journal of Nanomedicine. 2020 | Pubmed ID: 33281445 New Relationship of E2F1 and BNIP3 with Caveolin-1 in Lung Cancer-associated Fibroblasts Thoracic Cancer. Jun, 2020 | Pubmed ID: 32212370 Size- and Cell Type-dependent Cellular Uptake, Cytotoxicity and in Vivo Distribution of Gold Nanoparticles International Journal of Nanomedicine. 2019 | Pubmed ID: 32021157 A Comparative Study on the Effects of Quinic Acid and Shikimic Acid on Cellular Functions of Staphylococcus Aureus Journal of Food Protection. Jul, 2018 | Pubmed ID: 29939792 Reversibly Disulfide Cross-linked Micelles Improve the Pharmacokinetics and Facilitate the Targeted, On-demand Delivery of Doxorubicin in the Treatment of B-cell Lymphoma Nanoscale. May, 2018 | Pubmed ID: 29682647 Uptake, Distribution, Clearance, and Toxicity of Iron Oxide Nanoparticles with Different Sizes and Coatings Scientific Reports. Feb, 2018 | Pubmed ID: 29391477 Antibacterial Effect of 2R,3R-dihydromyricetin on the Cellular Functions of Staphylococcus Aureus Bioscience, Biotechnology, and Biochemistry. Jan, 2018 | Pubmed ID: 29235425 "One-Pot" Fabrication of Highly Versatile and Biocompatible Poly(vinyl Alcohol)-porphyrin-based Nanotheranostics Theranostics. 2017 | Pubmed ID: 29109786 Extremely Long Tumor Retention, Multi-responsive Boronate Crosslinked Micelles with Superior Therapeutic Efficacy for Ovarian Cancer Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2017 | Pubmed ID: 28847739 Sub-100nm, Long Tumor Retention SN-38-loaded Photonic Micelles for Tri-modal Cancer Therapy Journal of Controlled Release : Official Journal of the Controlled Release Society. Sep, 2017 | Pubmed ID: 28700898 A Facile Strategy for Fine-tuning the Stability and Drug Release of Stimuli-responsive Cross-linked Micellar Nanoparticles Towards Precision Drug Delivery Nanoscale. Jun, 2017 | Pubmed ID: 28585953 Temporal Analysis of Blood-brain Barrier Disruption and Cerebrospinal Fluid Matrix Metalloproteinases in Rhesus Monkeys Subjected to Transient Ischemic Stroke Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Aug, 2017 | Pubmed ID: 27885100 The Effect of Particle Size on the Genotoxicity of Gold Nanoparticles Journal of Biomedical Materials Research. Part A. Mar, 2017 | Pubmed ID: 27770565 Pharmacokinetic Behaviors of Intravenously Administered SiRNA in Glandular Tissues Theranostics. 2016 | Pubmed ID: 27446488 Role of Surface Charge in Determining the Biological Effects of CdSe/ZnS Quantum Dots International Journal of Nanomedicine. 2015 | Pubmed ID: 26604757 Vascular Endothelial Growth Factor Receptor 2 Antibody, BC001, Attenuates Laser-Induced Choroidal Neovascularization in Rhesus Monkeys (Macaca Mulatta) Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association for Ocular Pharmacology and Therapeutics. Dec, 2015 | Pubmed ID: 26334588 Disulfide Cross-linked Micelles of Novel HDAC Inhibitor Thailandepsin A for the Treatment of Breast Cancer Biomaterials. Oct, 2015 | Pubmed ID: 26218744 A Drug-specific Nanocarrier Design for Efficient Anticancer Therapy Nature Communications. Jul, 2015 | Pubmed ID: 26158623 Genotoxicity Assessment of Magnetic Iron Oxide Nanoparticles with Different Particle Sizes and Surface Coatings Nanotechnology. Oct, 2014 | Pubmed ID: 25274166 "OA02" Peptide Facilitates the Precise Targeting of Paclitaxel-loaded Micellar Nanoparticles to Ovarian Cancer in Vivo Cancer Research. Apr, 2012 | Pubmed ID: 22396491 Earthquake Distresses Reproductive Function but Not Fetal Development in Rats Birth Defects Research. Part B, Developmental and Reproductive Toxicology. Feb, 2012 | Pubmed ID: 22140077 PEG-oligocholic Acid Telodendrimer Micelles for the Targeted Delivery of Doxorubicin to B-cell Lymphoma Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2011 | Pubmed ID: 21787818 Well-defined, Reversible Disulfide Cross-linked Micelles for On-demand Paclitaxel Delivery Biomaterials. Sep, 2011 | Pubmed ID: 21658763 The Effect of Surface Charge on in Vivo Biodistribution of PEG-oligocholic Acid Based Micellar Nanoparticles Biomaterials. May, 2011 | Pubmed ID: 21295849 A Novel Size-tunable Nanocarrier System for Targeted Anticancer Drug Delivery Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2010 | Pubmed ID: 20211210 A Self-assembling Nanoparticle for Paclitaxel Delivery in Ovarian Cancer Biomaterials. Oct, 2009 | Pubmed ID: 19660809 [Toxicity of Caowu on in Vitro Cultured Rat Embryos] Sichuan Da Xue Xue Bao. Yi Xue Ban = Journal of Sichuan University. Medical Science Edition. May, 2008 | Pubmed ID: 18575336 Online Preconcentration and Determination of Trace Amounts of Zinc in Nature Waters Journal of Automated Methods & Management in Chemistry. 2008 | Pubmed ID: 18389074 Study of Aconitine Toxicity in Rat Embryos in Vitro Birth Defects Research. Part B, Developmental and Reproductive Toxicology. Jun, 2007 | Pubmed ID: 17570135 Estabelecimento e Caracterização de Modelos de Xenoenxerto Derivado de Pacientes de Carcinoma Anaplásico de Tireoide e Carcinoma Espinocelular de Cabeça e Pescoço Maodi Wu1,3, Yang Liu2, Yi Zhao3, Yuyao Zhang4, Liansi Huang3, Qijun Du3, Ting Zhang1,3, Zhihui Zhong1,3, Han Luo2, Kai Xiao1,3 1Precision Medicine Research Center, Sichuan Provincial Key Laboratory of Precision Medicine, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, 2Department of Thyroid Surgery, West China Hospital, Sichuan University, 3Sichuan Kangcheng Biotech Co., 4Sichuan Cancer Hospital JoVE 64623 Cancer Research
Estabelecimento e Caracterização de Modelos de Xenoenxerto Derivado de Pacientes de Carcinoma Anaplásico de Tireoide e Carcinoma Espinocelular de Cabeça e Pescoço Maodi Wu1,3, Yang Liu2, Yi Zhao3, Yuyao Zhang4, Liansi Huang3, Qijun Du3, Ting Zhang1,3, Zhihui Zhong1,3, Han Luo2, Kai Xiao1,3 1Precision Medicine Research Center, Sichuan Provincial Key Laboratory of Precision Medicine, National Clinical Research Center for Geriatrics, West China Hospital, Sichuan University, 2Department of Thyroid Surgery, West China Hospital, Sichuan University, 3Sichuan Kangcheng Biotech Co., 4Sichuan Cancer Hospital JoVE 64623 Cancer Research
