Kathleen Gabrielson

Department of Molecular and Comparative Pathobiology, The Johns Hopkins University School of Medicine

Affiliated withThe Johns Hopkins University School of Medicine Johns Hopkins University Johns Hopkins University School of Medicine

Research Area

Cancer Research

Biography

Kathleen Gabrielson has not added Biography.
If you are Kathleen Gabrielson and would like to personalize this page please email our Author Liaison for assistance.

JoVE Journal Publications

ArticleTotal : 2	Year
Publication title Cited by 6	2021
Publication title Cited by 1	2023

Other Publications

Article	Year
Mitochondrial toxin 3-nitropropionic acid induces cardiac and neurotoxicity differentially in mice. The American journal of pathology\| PubMed ID: 11583977	2001
Heat shock protein 90 and ErbB2 in the cardiac response to doxorubicin injury. Cancer research\| PubMed ID: 17308081	2007
Spontaneous lesions in the reproductive tract and mammary gland of female non-human primates. Birth defects research. Part B, Developmental and reproductive toxicology\| PubMed ID: 17342758	2007
Detection of dose response in chronic doxorubicin-mediated cell death with cardiac technetium 99m annexin V single-photon emission computed tomography. Molecular imaging\| PubMed ID: 19123983	2008
Gastric wall healing after NOTES procedures: closure with endoscopic clips provides superior histological outcome compared with threaded tags closure. Gastrointestinal endoscopy\| PubMed ID: 20674622	2010
Endothelial expression of hypoxia-inducible factor 1 protects the murine heart and aorta from pressure overload by suppression of TGF-β signaling. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22403061	2012
X-ray-visible microcapsules containing mesenchymal stem cells improve hind limb perfusion in a rabbit model of peripheral arterial disease. Stem cells (Dayton, Ohio)\| PubMed ID: 22438076	2012
Fatal eosinophilic myocarditis develops in the absence of IFN-γ and IL-17A. Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 24048893	2013
Geranylgeranylacetone blocks doxorubicin-induced cardiac toxicity and reduces cancer cell growth and invasion through RHO pathway inhibition. Molecular cancer therapeutics\| PubMed ID: 24737026	2014
Fused X-ray and MR imaging guidance of intrapericardial delivery of microencapsulated human mesenchymal stem cells in immunocompetent swine. Radiology\| PubMed ID: 24749713	2014
ErbB2 overexpression upregulates antioxidant enzymes, reduces basal levels of reactive oxygen species, and protects against doxorubicin cardiotoxicity. American journal of physiology. Heart and circulatory physiology\| PubMed ID: 26254336	2015
Electrocardiographic Characterization of Cardiac Hypertrophy in Mice that Overexpress the ErbB2 Receptor Tyrosine Kinase. Comparative medicine\| PubMed ID: 26310459	2015
Imaging transplanted stem cells in real time using an MRI dual-contrast method. Scientific reports\| PubMed ID: 26330231	2015
Bidirectional cross-regulation between ErbB2 and β-adrenergic signalling pathways. Cardiovascular research\| PubMed ID: 26692570	2016
A preclinical murine model for the early detection of radiation-induced brain injury using magnetic resonance imaging and behavioral tests for learning and memory: with applications for the ... Journal of neuro-oncology\| PubMed ID: 27021492	2016
Echocardiographic Characterization of a Murine Model of Hypertrophic Obstructive Cardiomyopathy Induced by Cardiac-specific Overexpression of Epidermal Growth Factor Receptor 2. Comparative medicine\| PubMed ID: 27538857	2016
Enhancing the abscopal effect of radiation and immune checkpoint inhibitor therapies with magnetic nanoparticle hyperthermia in a model of metastatic breast cancer. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group\| PubMed ID: 31795835	2019
Prenatal stress enhances NNK-induced lung tumors in A/J mice. Carcinogenesis\| PubMed ID: 32249286	2020
Development of 5D3-DM1: A Novel Anti-Prostate-Specific Membrane Antigen Antibody-Drug Conjugate for PSMA-Positive Prostate Cancer Therapy. Molecular pharmaceutics\| PubMed ID: 32803984	2020
Aging impairs the beneficial effect of granulocyte colony-stimulating factor and stem cell factor on post-myocardial infarction remodeling. Circulation research\| PubMed ID: 16873716	2006
Apoptosis has a prolonged role in the neurodegeneration after hypoxic ischemia in the newborn rat. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 11050120	2000
Protection from doxorubicin-induced cardiac toxicity in mice with a null allele of carbonyl reductase 1. Cancer research\| PubMed ID: 14583452	2003
TGF-beta-dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome. The Journal of clinical investigation\| PubMed ID: 15546004	2004
A functional floxed allele of Pkd1 that can be conditionally inactivated in vivo. Journal of the American Society of Nephrology : JASN\| PubMed ID: 15579506	2004
Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome. Science (New York, N.Y.)\| PubMed ID: 16601194	2006
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers. Cancer research\| PubMed ID: 17332349	2007
Interleukin-13 protects against experimental autoimmune myocarditis by regulating macrophage differentiation. The American journal of pathology\| PubMed ID: 18403598	2008
Etanercept, a TNF-alpha binding agent, is ineffective in the prevention of post-ERCP pancreatitis in canines. JOP : Journal of the pancreas\| PubMed ID: 18648137	2008
An orally bioavailable small-molecule inhibitor of Hedgehog signaling inhibits tumor initiation and metastasis in pancreatic cancer. Molecular cancer therapeutics\| PubMed ID: 18790753	2008
Phosphodiesterase 5 inhibition blocks pressure overload-induced cardiac hypertrophy independent of the calcineurin pathway. Cardiovascular research\| PubMed ID: 19029137	2009
Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice. The Journal of clinical investigation\| PubMed ID: 19127022	2009
Adverse ventricular remodeling and exacerbated NOS uncoupling from pressure-overload in mice lacking the beta3-adrenoreceptor. Journal of molecular and cellular cardiology\| PubMed ID: 19766235	2009
Evidence for a role of immunoproteasomes in regulating cardiac muscle mass in diabetic mice. Journal of molecular and cellular cardiology\| PubMed ID: 20153750	2010
Interleukin-17A is dispensable for myocarditis but essential for the progression to dilated cardiomyopathy. Circulation research\| PubMed ID: 20378858	2010
Myocardial remodeling is controlled by myocyte-targeted gene regulation of phosphodiesterase type 5. Journal of the American College of Cardiology\| PubMed ID: 20970280	2010
The innate immune response to coxsackievirus B3 predicts progression to cardiovascular disease and heart failure in male mice. Biology of sex differences\| PubMed ID: 21338512	2011
Th2 regulation of viral myocarditis in mice: different roles for TLR3 versus TRIF in progression to chronic disease. Clinical & developmental immunology\| PubMed ID: 22013485	2012
Acute renal venous obstruction is more detrimental to the kidney than arterial occlusion: implication for murine models of acute kidney injury. American journal of physiology. Renal physiology\| PubMed ID: 22114209	2012
Dose-dependent depth of tissue injury with carbon dioxide cryotherapy in porcine GI tract. Gastrointestinal endoscopy\| PubMed ID: 22301345	2012
Cardioprotective effect of beta-3 adrenergic receptor agonism: role of neuronal nitric oxide synthase. Journal of the American College of Cardiology\| PubMed ID: 22624839	2012
A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy. Oncotarget\| PubMed ID: 22791660	2012
Beneficial cardiac effects of caloric restriction are lost with age in a murine model of obesity. Journal of cardiovascular translational research\| PubMed ID: 23456569	2013
Anti-hypertrophic and anti-oxidant effect of beta3-adrenergic stimulation in myocytes requires differential neuronal NOS phosphorylation. Journal of molecular and cellular cardiology\| PubMed ID: 23643588	2013
Endocardial endothelium is a key determinant of force-frequency relationship in rat ventricular myocardium. Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 23703113	2013
A Pkd1-Fbn1 genetic interaction implicates TGF-β signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease. Journal of the American Society of Nephrology : JASN\| PubMed ID: 24071006	2014
Generation of a cre recombinase-conditional Nos1ap over-expression transgenic mouse. Biotechnology letters\| PubMed ID: 24563304	2014
A novel viscous dissecting gel for endoscopic submucosal dissection: a prospective survival study in a porcine model. Endoscopy\| PubMed ID: 24770967	2014
Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain. The EMBO journal\| PubMed ID: 25349190	2014
Targeting DDX3 with a small molecule inhibitor for lung cancer therapy. EMBO molecular medicine\| PubMed ID: 25820276	2015
An Fc-Small Molecule Conjugate for Targeted Inhibition of the Adenosine 2A Receptor. Chembiochem : a European journal of chemical biology\| PubMed ID: 27432157	2016
RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3. Cancer research\| PubMed ID: 27634756	2016
Stationary phase persister/biofilm microcolony of Borrelia burgdorferi causes more severe disease in a mouse model of Lyme arthritis: implications for understanding persistence, Post-treatme... Discovery medicine\| PubMed ID: 30946803	2019
Noninvasive Monitoring of Allogeneic Stem Cell Delivery with Dual-Modality Imaging-Visible Microcapsules in a Rabbit Model of Peripheral Arterial Disease. Stem cells international\| PubMed ID: 31001343	2019
Fropofol prevents disease progression in mice with hypertrophic cardiomyopathy. Cardiovascular research\| PubMed ID: 31424496	2020
Engineered nanoparticles for systemic siRNA delivery to malignant brain tumours. Nanoscale\| PubMed ID: 31612183	2019
Induction of STK11-dependent cytoprotective autophagy in breast cancer cells upon honokiol treatment. Cell death discovery\| PubMed ID: 32963809
A Procarcinogenic Colon Microbe Promotes Breast Tumorigenesis and Metastatic Progression and Concomitantly Activates Notch and β-Catenin Axes. Cancer discovery\| PubMed ID: 33408241	2021
FATAL RANAVIRUS INFECTION IN A GROUP OF ZOO-HOUSED MELLER'S CHAMELEONS (). Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians\| PubMed ID: 33517641	2019
An Improved At-Labeled Agent for PSMA-Targeted α-Therapy. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 34088772	2022
GPCR-ErbB transactivation pathways and clinical implications. Cellular signalling\| PubMed ID: 34303814	2021
CRYβB2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer. Oncogene\| PubMed ID: 34341513	2021
Hepatic Steatosis in the Mouse Model of Wilson Disease Coincides with a Muted Inflammatory Response. The American journal of pathology\| PubMed ID: 34627751	2022
Dual-Modality PET-SPECT Image-Guided Pretargeting Delivery in HER2(+) Breast Cancer Models. Biomacromolecules\| PubMed ID: 34704434	2021
Bionized Nanoferrite Particles Alter the Course of Experimental Cryptococcus neoformans Pneumonia. Antimicrobial agents and chemotherapy\| PubMed ID: 35293784	2022
Prenatal stress enhances atherosclerosis and telomere shortening in ApoE knockout mouse offspring. American journal of physiology. Regulatory, integrative and comparative physiology\| PubMed ID: 35411811	2022
The Common Marmoset-Biomedical Research Animal Model Applications and Common Spontaneous Diseases. Toxicologic pathology\| PubMed ID: 35535728	2022
Intraductal administration of transferrin receptor-targeted immunotoxin clears ductal carcinoma in situ in mouse models of breast cancer-a preclinical study. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 35675429	2022
Polymeric nanoparticles for dual-targeted theranostic gene delivery to hepatocellular carcinoma. Science advances\| PubMed ID: 35857843	2022
Canine Idiopathic Arteriopathy, Appendicular Bone Infarcts, and Neoplastic Transformation of Bone Infarcts in 108 Dogs (). Comparative medicine\| PubMed ID: 36113969	2022
HOXA5-Mediated Stabilization of IκBα Inhibits the NF-κB Pathway and Suppresses Malignant Transformation of Breast Epithelial Cells. Cancer research\| PubMed ID: 36166646	2022
Alteration in tyrosine phosphorylation of cardiac proteome and EGFR pathway contribute to hypertrophic cardiomyopathy. Communications biology\| PubMed ID: 36380187	2022
Comparison of Cardiovascular Pathology in Animal Models of SARS-CoV-2 Infection: Recommendations Regarding Standardization of Research Methods. Comparative medicine\| PubMed ID: 36731878	2023