Klaus B. Piontek

Division of Gastroenterology and Hepatology, Johns Hopkins University School of Medicine

Affiliated withJohns Hopkins University School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 17	2016

Other Publications

Article	Year
A functional floxed allele of Pkd1 that can be conditionally inactivated in vivo. Journal of the American Society of Nephrology : JASN\| PubMed ID: 15579506	2004
Loss of polycystin-1 or polycystin-2 results in dysregulated apolipoprotein expression in murine tissues via alterations in nuclear hormone receptors. Human molecular genetics\| PubMed ID: 16301212	2006
The mTOR pathway is regulated by polycystin-1, and its inhibition reverses renal cystogenesis in polycystic kidney disease. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16567633	2006
Genetic interaction studies link autosomal dominant and recessive polycystic kidney disease in a common pathway. Human molecular genetics\| PubMed ID: 17575307	2007
Inactivation of Pkd1 in principal cells causes a more severe cystic kidney disease than in intercalated cells. Kidney international\| PubMed ID: 19145237	2009
Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1. Molecular and cellular biology\| PubMed ID: 19255143	2009
Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1. Journal of the American Society of Nephrology : JASN\| PubMed ID: 20075061	2010
Pkd1 and Pkd2 are required for normal placental development. PloS one\| PubMed ID: 20862291	2010
Ectopic expression of Cux1 is associated with reduced p27 expression and increased apoptosis during late stage cyst progression upon inactivation of Pkd1 in collecting ducts. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 21465620	2011
Polycystin-1 regulates the stability and ubiquitination of transcription factor Jade-1. Human molecular genetics\| PubMed ID: 23001567	2012
Network analysis of a Pkd1-mouse model of autosomal dominant polycystic kidney disease identifies HNF4α as a disease modifier. PLoS genetics\| PubMed ID: 23209428	2012
Impaired glomerulogenesis and endothelial cell migration in Pkd1-deficient renal organ cultures. Biochemical and biophysical research communications\| PubMed ID: 24472557	2014
Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression. Oncology reports\| PubMed ID: 24841903	2014
MicroRNA-224 Induces G1/S Checkpoint Release in Liver Cancer. Journal of clinical medicine\| PubMed ID: 26343737	2015