Kristoffer Valerie

Department of Radiation Oncology, Virginia Commonwealth University

Affiliated withVirginia Commonwealth University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 4	2012

Other Publications

Article	Year
Radiosensitization of human glioma cells in vitro and in vivo with acyclovir and mutant HSV-TK75 expressed from adenovirus. International journal of radiation oncology, biology, physics\| PubMed ID: 11849808	2002
Ionizing radiation activates Erb-B receptor dependent Akt and p70 S6 kinase signaling in carcinoma cells. Oncogene\| PubMed ID: 12037685	2002
UVB-mediated activation of p38 mitogen-activated protein kinase enhances resistance of normal human keratinocytes to apoptosis by stabilizing cytoplasmic p53. The Biochemical journal\| PubMed ID: 12071847	2002
mda-7 (IL-24) Mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12114539	2002
Epidermal growth factor receptor dependence of radiation-induced transcription factor activation in human breast carcinoma cells. Molecular biology of the cell\| PubMed ID: 12134064	2002
SAGE transcript profiles of normal primary human hepatocytes expressing oncogenic hepatitis B virus X protein. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 12207007	2002
Identification and cloning of human polynucleotide phosphorylase, hPNPase old-35, in the context of terminal differentiation and cellular senescence. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12473748	2002
Stress and radiation-induced activation of multiple intracellular signaling pathways. Radiation research\| PubMed ID: 12600231	2003
BLM helicase-dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination. The EMBO journal\| PubMed ID: 12606585	2003
Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner. Oncogene\| PubMed ID: 12606943	2003
Mood-enhancing antidepressant St. John's wort inhibits the activation of human immunodeficiency virus gene expression by ultraviolet light. IUBMB life\| PubMed ID: 12665247	2002
Bile acid regulation of C/EBPbeta, CREB, and c-Jun function, via the extracellular signal-regulated kinase and c-Jun NH2-terminal kinase pathways, modulates the apoptotic response of hepatoc... Molecular and cellular biology\| PubMed ID: 12697808	2003
Down-regulation of Myc as a potential target for growth arrest induced by human polynucleotide phosphorylase (hPNPaseold-35) in human melanoma cells. The Journal of biological chemistry\| PubMed ID: 12721301	2003
Dominant-negative cAMP-responsive element-binding protein inhibits proliferating cell nuclear antigen and DNA repair, leading to increased cellular radiosensitivity. The Journal of biological chemistry\| PubMed ID: 12734192	2003
Adenovirus expressing p53. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 12824521	2003
Involvement of Crm1 in hepatitis B virus X protein-induced aberrant centriole replication and abnormal mitotic spindles. Molecular and cellular biology\| PubMed ID: 12861014	2003
MDA-7 (interleukin-24) inhibits the proliferation of renal carcinoma cells and interacts with free radicals to promote cell death and loss of reproductive capacity. Molecular cancer therapeutics\| PubMed ID: 12883035	2003
EGFRvIII-mediated radioresistance through a strong cytoprotective response. Oncogene\| PubMed ID: 12944901	2003
Regulation and mechanisms of mammalian double-strand break repair. Oncogene\| PubMed ID: 12947387	2003
Triggering of apoptosis is not sufficient to induce human immunodeficiency virus gene expression. IUBMB life\| PubMed ID: 14584593	2003
Curcumin inhibits ultraviolet light induced human immunodeficiency virus gene expression. Molecular and cellular biochemistry\| PubMed ID: 14674708	2003
Expression analysis and genomic characterization of human melanoma differentiation associated gene-5, mda-5: a novel type I interferon-responsive apoptosis-inducing gene. Oncogene\| PubMed ID: 14676839	2004
Activation of the stress-activated JNK and p38 MAP kinases in human cells by Photofrin-mediated photodynamic therapy. Journal of photochemistry and photobiology. B, Biology\| PubMed ID: 14705642	2003
Double strand break repair by homologous recombination is regulated by cell cycle-independent signaling via ATM in human glioma cells. The Journal of biological chemistry\| PubMed ID: 14744854	2004
Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways. Cancer research\| PubMed ID: 15126330	2004
Radiation-induced activation of a common variant of EGFR confers enhanced radioresistance. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology\| PubMed ID: 15450724	2004
Inhibition of the type III epidermal growth factor receptor variant mutant receptor by dominant-negative EGFR-CD533 enhances malignant glioma cell radiosensitivity. Clinical cancer research : an official journal of the American Association for Cancer Research\| PubMed ID: 15475464	2004
Targeting gene expression selectively in cancer cells by using the progression-elevated gene-3 promoter. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15647352	2005
Deficiency in 3'-phosphoglycolate processing in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1). Nucleic acids research\| PubMed ID: 15647511	2005
Requirement of Tyr-992 and Tyr-1173 in phosphorylation of the epidermal growth factor receptor by ionizing radiation and modulation by SHP2. The Journal of biological chemistry\| PubMed ID: 15708852	2005
Defining the domains of human polynucleotide phosphorylase (hPNPaseOLD-35) mediating cellular senescence. Molecular and cellular biology\| PubMed ID: 16055741	2005
Targeted virus replication plus immunotherapy eradicates primary and distant pancreatic tumors in nude mice. Cancer research\| PubMed ID: 16204080	2005
Radiosensitization of MDA-MB-231 breast tumor cells by adenovirus-mediated overexpression of a fragment of the XRCC4 protein. Molecular cancer therapeutics\| PubMed ID: 16227403	2005
Compensatory ErbB3/c-Src signaling enhances carcinoma cell survival to ionizing radiation. Breast cancer research and treatment\| PubMed ID: 16267617	2006
mda-9/Syntenin: a positive regulator of melanoma metastasis. Cancer research\| PubMed ID: 16322237	2005
Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis. Cancer research\| PubMed ID: 16452207	2006
Molecular target-based therapy of pancreatic cancer. Cancer research\| PubMed ID: 16489047	2006
ErbB receptor tyrosine kinase network inhibition radiosensitizes carcinoma cells. International journal of radiation oncology, biology, physics\| PubMed ID: 16751066	2006
Effect of hepatitis C virus core protein on the molecular profiling of human B lymphocytes. Molecular medicine (Cambridge, Mass.)\| PubMed ID: 16838065	2006
BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis. Cancer research\| PubMed ID: 16912197	2006
Human chorionic gonadotropin modulates prostate cancer cell survival after irradiation or HMG CoA reductase inhibitor treatment. Molecular pharmacology\| PubMed ID: 17050804	2007
N-glycosylation of MDA-7/IL-24 is dispensable for tumor cell-specific apoptosis and "bystander" antitumor activity. Cancer research\| PubMed ID: 17178884	2006
Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response. Cancer research\| PubMed ID: 17283137	2007
辐射诱导细胞内信号传递：内外和外而内。 Molecular cancer therapeutics\| PubMed ID: 17363476	2007
Phosphorylation in the serine/threonine 2609-2647 cluster promotes but is not essential for DNA-dependent protein kinase-mediated nonhomologous end joining in human whole-cell extracts. Nucleic acids research\| PubMed ID: 17526517	2007
Progression elevated gene-3 promoter (PEG-Prom) confers cancer cell selectivity to human polynucleotide phosphorylase (hPNPase(old-35))-mediated growth suppression. Journal of cellular physiology\| PubMed ID: 17960560	2008
Novel mode for neutrophil protease cathepsin G-mediated signaling: membrane shedding of epidermal growth factor is required for cardiomyocyte anoikis. Circulation research\| PubMed ID: 17975113	2008
Coordinate 5' and 3' endonucleolytic trimming of terminally blocked blunt DNA double-strand break ends by Artemis nuclease and DNA-dependent protein kinase. Nucleic acids research\| PubMed ID: 18440975	2008
Cloning and characterization of SARI (suppressor of AP-1, regulated by IFN). Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19074269	2008
In vitro complementation of Tdp1 deficiency indicates a stabilized enzyme-DNA adduct from tyrosyl but not glycolate lesions as a consequence of the SCAN1 mutation. DNA repair\| PubMed ID: 19211312	2009
Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells. Cancer biology & therapy\| PubMed ID: 19252415	2009
Nuclear factor I isoforms regulate gene expression during the differentiation of human neural progenitors to astrocytes. Stem cells (Dayton, Ohio)\| PubMed ID: 19418463	2009
Requirement for XLF/Cernunnos in alignment-based gap filling by DNA polymerases lambda and mu for nonhomologous end joining in human whole-cell extracts. Nucleic acids research\| PubMed ID: 19420065	2009
Tyrosyl-DNA phosphodiesterase and the repair of 3'-phosphoglycolate-terminated DNA double-strand breaks. DNA repair\| PubMed ID: 19505854	2009
Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion. Molecular cancer therapeutics\| PubMed ID: 19808981	2009
Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants. PloS one\| PubMed ID: 20368801	2010
ATM-independent, high-fidelity nonhomologous end joining predominates in human embryonic stem cells. Aging\| PubMed ID: 20844317	2010
ATM-dependent ERK signaling via AKT in response to DNA double-strand breaks. Cell cycle (Georgetown, Tex.)\| PubMed ID: 21263216	2011
Mutations in the BRCT binding site of BRCA1 result in hyper-recombination. Aging\| PubMed ID: 21666281	2011
DNA double-strand break - induced pro-survival signaling. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology\| PubMed ID: 21726915	2011
MRE11 and ATM AKTivate pro-survival signaling. Cell cycle (Georgetown, Tex.)\| PubMed ID: 21946569	2011
Nanomaterial-mediated CNS delivery of diagnostic and therapeutic agents. Advanced drug delivery reviews\| PubMed ID: 22178615	2012
BRCA1-directed, enhanced and aberrant homologous recombination: mechanism and potential treatment strategies. Cell cycle (Georgetown, Tex.)\| PubMed ID: 22306997	2012
Dynamic inhibition of ATM kinase provides a strategy for glioblastoma multiforme radiosensitization and growth control. Cell cycle (Georgetown, Tex.)\| PubMed ID: 22370485	2012