Laurence G. Rahme Shriners Burn Institute Biography Publications Institution JoVE Articles Laurence G. Rahme has not added a biography. If you are Laurence G. Rahme and would like to personalize this page please email our Author Liaison for assistance. Publications Down-regulation of Glutatione S-transferase α 4 (hGSTA4) in the Muscle of Thermally Injured Patients is Indicative of Susceptibility to Bacterial Infection FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Feb, 2012 | Pubmed ID: 22038048 A Quorum Sensing Regulated Small Volatile Molecule Reduces Acute Virulence and Promotes Chronic Infection Phenotypes PLoS Pathogens. Aug, 2011 | Pubmed ID: 21829370 Combining Magnetic Resonance Spectroscopy and Molecular Genomics Offers Better Accuracy in Brain Tumor Typing and Prediction of Survival Than Either Methodology Alone International Journal of Oncology. Apr, 2011 | Pubmed ID: 21274507 Drosophila Melanogaster As a Model for Human Intestinal Infection and Pathology Disease Models & Mechanisms. Jan, 2011 | Pubmed ID: 21183483 Nuclear Magnetic Resonance in Conjunction with Functional Genomics Suggests Mitochondrial Dysfunction in a Murine Model of Cancer Cachexia International Journal of Molecular Medicine. Jan, 2011 | Pubmed ID: 21069263 Combined Off-resonance Imaging and T2 Relaxation in the Rotating Frame for Positive Contrast MR Imaging of Infection in a Murine Burn Model Journal of Magnetic Resonance Imaging : JMRI. Nov, 2010 | Pubmed ID: 21031524 In Vivo High-resolution Magic Angle Spinning Magnetic Resonance Spectroscopy of Drosophila Melanogaster at 14.1 T Shows Trauma in Aging and in Innate Immune-deficiency is Linked to Reduced Insulin Signaling International Journal of Molecular Medicine. Aug, 2010 | Pubmed ID: 20596596 Homeostatic Interplay Between Bacterial Cell-cell Signaling and Iron in Virulence PLoS Pathogens. Mar, 2010 | Pubmed ID: 20300606 The Pathogenic Properties of a Novel and Conserved Gene Product, KerV, in Proteobacteria PloS One. 2009 | Pubmed ID: 19779606 Dysfunctional Expansion of Hematopoietic Stem Cells and Block of Myeloid Differentiation in Lethal Sepsis Blood. Nov, 2009 | Pubmed ID: 19696201 Drosophila Melanogaster As a Model Host for Studying Pseudomonas Aeruginosa Infection Nature Protocols. 2009 | Pubmed ID: 19680242 Microarray Analysis Suggests That Burn Injury Results in Mitochondrial Dysfunction in Human Skeletal Muscle International Journal of Molecular Medicine. Sep, 2009 | Pubmed ID: 19639232 Modeling Pseudomonas Aeruginosa Pathogenesis in Plant Hosts Nature Protocols. 2009 | Pubmed ID: 19180083 Burn Trauma in Skeletal Muscle Results in Oxidative Stress As Assessed by in Vivo Electron Paramagnetic Resonance Molecular Medicine Reports. 2008 | Pubmed ID: 21179378 Murine Intramyocellular Lipids Quantified by NMR Act As Metabolic Biomarkers in Burn Trauma International Journal of Molecular Medicine. Jun, 2008 | Pubmed ID: 18506378 Use of the Lambda Red Recombinase System to Rapidly Generate Mutants in Pseudomonas Aeruginosa BMC Molecular Biology. 2008 | Pubmed ID: 18248677 Reduced Rate of Adenosine Triphosphate Synthesis by in Vivo 31P Nuclear Magnetic Resonance Spectroscopy and Downregulation of PGC-1beta in Distal Skeletal Muscle Following Burn International Journal of Molecular Medicine. Feb, 2008 | Pubmed ID: 18204786 Involvement of Skeletal Muscle Gene Regulatory Network in Susceptibility to Wound Infection Following Trauma PloS One. 2007 | Pubmed ID: 18159239 Inhibitors of Pathogen Intercellular Signals As Selective Anti-infective Compounds PLoS Pathogens. Sep, 2007 | Pubmed ID: 17941706 PqsA is Required for the Biosynthesis of 2,4-dihydroxyquinoline (DHQ), a Newly Identified Metabolite Produced by Pseudomonas Aeruginosa and Burkholderia Thailandensis Biological Chemistry. Aug, 2007 | Pubmed ID: 17655503 Combination of High-resolution Magic Angle Spinning Proton Magnetic Resonance Spectroscopy and Microscale Genomics to Type Brain Tumor Biopsies International Journal of Molecular Medicine. Aug, 2007 | Pubmed ID: 17611638 Dynorphin Activates Quorum Sensing Quinolone Signaling in Pseudomonas Aeruginosa PLoS Pathogens. Mar, 2007 | Pubmed ID: 17367209 Uncoupling Protein 3 Expression and Intramyocellular Lipid Accumulation by NMR Following Local Burn Trauma International Journal of Molecular Medicine. Dec, 2006 | Pubmed ID: 17089030 MvfR, a Key Pseudomonas Aeruginosa Pathogenicity LTTR-class Regulatory Protein, Has Dual Ligands Molecular Microbiology. Dec, 2006 | Pubmed ID: 17083468 Genomic Analysis Reveals That Pseudomonas Aeruginosa Virulence is Combinatorial Genome Biology. 2006 | Pubmed ID: 17038190 Local and Distant Burn Injury Alter Immuno-inflammatory Gene Expression in Skeletal Muscle The Journal of Trauma. Aug, 2006 | Pubmed ID: 16917440 Mutation Analysis of the Pseudomonas Aeruginosa MvfR and PqsABCDE Gene Promoters Demonstrates Complex Quorum-sensing Circuitry Microbiology (Reading, England). Jun, 2006 | Pubmed ID: 16735731 Proton NMR Spectroscopy Shows Lipids Accumulate in Skeletal Muscle in Response to Burn Trauma-induced Apoptosis FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Sep, 2005 | Pubmed ID: 16126910 Burn Injury Causes Mitochondrial Dysfunction in Skeletal Muscle Proceedings of the National Academy of Sciences of the United States of America. Apr, 2005 | Pubmed ID: 15809440 Profiling Early Infection Responses: Pseudomonas Aeruginosa Eludes Host Defenses by Suppressing Antimicrobial Peptide Gene Expression Proceedings of the National Academy of Sciences of the United States of America. Feb, 2005 | Pubmed ID: 15695583 The Contribution of MvfR to Pseudomonas Aeruginosa Pathogenesis and Quorum Sensing Circuitry Regulation: Multiple Quorum Sensing-regulated Genes Are Modulated Without Affecting LasRI, RhlRI or the Production of N-acyl-L-homoserine Lactones Molecular Microbiology. Feb, 2005 | Pubmed ID: 15686549 Electrospray/mass Spectrometric Identification and Analysis of 4-hydroxy-2-alkylquinolines (HAQs) Produced by Pseudomonas Aeruginosa Journal of the American Society for Mass Spectrometry. Jun, 2004 | Pubmed ID: 15144975 Challenge of Drosophila Melanogaster with Cryptococcus Neoformans and Role of the Innate Immune Response Eukaryotic Cell. Apr, 2004 | Pubmed ID: 15075271 The Broad Host Range Pathogen Pseudomonas Aeruginosa Strain PA14 Carries Two Pathogenicity Islands Harboring Plant and Animal Virulence Genes Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14983043 Analysis of Pseudomonas Aeruginosa 4-hydroxy-2-alkylquinolines (HAQs) Reveals a Role for 4-hydroxy-2-heptylquinoline in Cell-to-cell Communication Proceedings of the National Academy of Sciences of the United States of America. Feb, 2004 | Pubmed ID: 14739337 Pseudomonas Aeruginosa-plant Root Interactions. Pathogenicity, Biofilm Formation, and Root Exudation Plant Physiology. Jan, 2004 | Pubmed ID: 14701912 The Drosophila Melanogaster Toll Pathway Participates in Resistance to Infection by the Gram-negative Human Pathogen Pseudomonas Aeruginosa Infection and Immunity. Jul, 2003 | Pubmed ID: 12819096 Use of Plant and Insect Hosts to Model Bacterial Pathogenesis Methods in Enzymology. 2002 | Pubmed ID: 12474375 Identification of Virulence Genes in a Pathogenic Strain of Pseudomonas Aeruginosa by Representational Difference Analysis Journal of Bacteriology. Feb, 2002 | Pubmed ID: 11807055 Магнитно-резонансной спектроскопии живых Дрозофилы С помощью магии прядильной Угол Valeria Righi1,2,3, Yiorgos Apidianakis2,4, Laurence G. Rahme2,4, A. Aria Tzika1,2,3 1NMR Surgical Laboratory, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 2Shriners Burn Institute, 3Department of Radiology, Athinoula A. Martinos Center of Biomedical Imaging, Harvard Medical School, 4Molecular Surgery Laboratory, Department of Surgery, Massachusetts General Hospital, Harvard Medical School JoVE 1710 Neuroscience
Магнитно-резонансной спектроскопии живых Дрозофилы С помощью магии прядильной Угол Valeria Righi1,2,3, Yiorgos Apidianakis2,4, Laurence G. Rahme2,4, A. Aria Tzika1,2,3 1NMR Surgical Laboratory, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 2Shriners Burn Institute, 3Department of Radiology, Athinoula A. Martinos Center of Biomedical Imaging, Harvard Medical School, 4Molecular Surgery Laboratory, Department of Surgery, Massachusetts General Hospital, Harvard Medical School JoVE 1710 Neuroscience