Lisa M. Coussens Cell, Developmental & Cancer Biology Oregon Health & Science University Biography Publications Institution JoVE Articles Lisa M. Coussens has not added a biography. If you are Lisa M. Coussens and would like to personalize this page please email our Author Liaison for assistance. Publications Immune Escape in Breast Cancer During In Situ to Invasive Carcinoma Transition Cancer Discovery. Jun, 2017 | Pubmed ID: 28652380 Quantitative Multiplex Immunohistochemistry Reveals Myeloid-Inflamed Tumor-Immune Complexity Associated with Poor Prognosis Cell Reports. Apr, 2017 | Pubmed ID: 28380359 Colorectal Cancer Liver Metastasis: Evolving Paradigms and Future Directions Cellular and Molecular Gastroenterology and Hepatology. Mar, 2017 | Pubmed ID: 28275683 Trim32 Deficiency Enhances Th2 Immunity and Predisposes to Features of Atopic Dermatitis The Journal of Investigative Dermatology. Feb, 2017 | Pubmed ID: 27720760 MicroRNA Regulation of Endothelial TREX1 Reprograms the Tumour Microenvironment Nature Communications. Nov, 2016 | Pubmed ID: 27886180 AACR Cancer Progress Report 2016 Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Oct, 2016 | Pubmed ID: 27697776 Alk5 Inhibition Increases Delivery of Macromolecular and Protein-bound Contrast Agents to Tumors JCI Insight. May, 2016 | Pubmed ID: 27182558 Distinct Clinical Patterns and Immune Infiltrates Are Observed at Time of Progression on Targeted Therapy Versus Immune Checkpoint Blockade for Melanoma Oncoimmunology. Mar, 2016 | Pubmed ID: 27141370 The Basis of Oncoimmunology Cell. Mar, 2016 | Pubmed ID: 26967289 Bruton Tyrosine Kinase-Dependent Immune Cell Cross-talk Drives Pancreas Cancer Cancer Discovery. Mar, 2016 | Pubmed ID: 26715645 Lymphatic Vessels, Inflammation, and Immunity in Skin Cancer Cancer Discovery. Jan, 2016 | Pubmed ID: 26552413 Senescence and Cancer: An Evolving Inflammatory Paradox Biochimica Et Biophysica Acta. Jan, 2016 | Pubmed ID: 26453912 Immune Response to Cancer Therapy: Mounting an Effective Antitumor Response and Mechanisms of Resistance Trends in Cancer. Sep, 2015 | Pubmed ID: 26457331 Myeloid Cells As Targets for Therapy in Solid Tumors Cancer Journal (Sudbury, Mass.). Jul-Aug, 2015 | Pubmed ID: 26222088 Macrophages and Therapeutic Resistance in Cancer Cancer Cell. Apr, 2015 | Pubmed ID: 25858805 TH2-Polarized CD4(+) T Cells and Macrophages Limit Efficacy of Radiotherapy Cancer Immunology Research. May, 2015 | Pubmed ID: 25716473 Macrophage IL-10 Blocks CD8+ T Cell-dependent Responses to Chemotherapy by Suppressing IL-12 Expression in Intratumoral Dendritic Cells Cancer Cell. Nov, 2014 | Pubmed ID: 25446896 Duality of the Immune Response in Cancer: Lessons Learned from Skin The Journal of Investigative Dermatology. Oct, 2014 | Pubmed ID: 25302470 Manipulating MicroRNAs to Regulate Macrophage Polarization in Gliomas Journal of the National Cancer Institute. Aug, 2014 | Pubmed ID: 25136034 Mammary Gland Involution As an Immunotherapeutic Target for Postpartum Breast Cancer Journal of Mammary Gland Biology and Neoplasia. Jul, 2014 | Pubmed ID: 24952477 B Cells Regulate Macrophage Phenotype and Response to Chemotherapy in Squamous Carcinomas Cancer Cell. Jun, 2014 | Pubmed ID: 24909985 A Listeria Vaccine and Depletion of T-regulatory Cells Activate Immunity Against Early Stage Pancreatic Intraepithelial Neoplasms and Prolong Survival of Mice Gastroenterology. Jun, 2014 | Pubmed ID: 24607504 CSF1R Inhibition Delays Cervical and Mammary Tumor Growth in Murine Models by Attenuating the Turnover of Tumor-associated Macrophages and Enhancing Infiltration by CD8(+) T Cells Oncoimmunology. Dec, 2013 | Pubmed ID: 24498562 Poker Face No More: Cancer Recurrence Reveals Its Hand Nature Medicine. Dec, 2013 | Pubmed ID: 24309652 Dendritic Cells, Inflammation, and Breast Cancer Cancer Journal (Sudbury, Mass.). Nov-Dec, 2013 | Pubmed ID: 24270350 Cathepsin C is a Tissue-specific Regulator of Squamous Carcinogenesis Genes & Development. Oct, 2013 | Pubmed ID: 24065739 Tumor-infiltrating Regulatory T Cells Inhibit Endogenous Cytotoxic T Cell Responses to Lung Adenocarcinoma Journal of Immunology (Baltimore, Md. : 1950). Aug, 2013 | Pubmed ID: 23851682 Some DCs Are "B"etter Immunity. Apr, 2013 | Pubmed ID: 23601679 B Cells and Their Mediators As Targets for Therapy in Solid Tumors Experimental Cell Research. Jul, 2013 | Pubmed ID: 23499742 Neutralizing Tumor-promoting Chronic Inflammation: a Magic Bullet? Science (New York, N.Y.). Jan, 2013 | Pubmed ID: 23329041 MR Imaging of Tumor-associated Macrophages Oncoimmunology. Jul, 2012 | Pubmed ID: 22754769 Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment Cancer Cell. Mar, 2012 | Pubmed ID: 22439926 Complejidad De Microentorno Del Tumor: Nuevas Funciones En Terapia Del Cáncer Cancer Research. May, 2012 | Pubmed ID: 22414581 Differential Macrophage Programming in the Tumor Microenvironment Trends in Immunology. Mar, 2012 | Pubmed ID: 22277903 Leukocyte Composition of Human Breast Cancer Proceedings of the National Academy of Sciences of the United States of America. Feb, 2012 | Pubmed ID: 21825174 Protective Role of Cathepsin L in Mouse Skin Carcinogenesis Molecular Carcinogenesis. Apr, 2012 | Pubmed ID: 21538579 Immune Microenvironments in Solid Tumors: New Targets for Therapy Genes & Development. Dec, 2011 | Pubmed ID: 22190457 Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy Cancer Discovery. Jun, 2011 | Pubmed ID: 22039576 RM De Tumores Asociados a Los Macrófagos Con Nanopartículas De óxido De Hierro Clínicamente Aplicable Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2011 | Pubmed ID: 21791632 B Regulatory Cells and the Tumor-promoting Actions of TNF-α During Squamous Carcinogenesis Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011 | Pubmed ID: 21670304 Leucocitos Paracrina Regulador De Metástasis Y Determinantes De La Colonización De órganos Específicos International Journal of Cancer. Journal International Du Cancer. Jun, 2011 | Pubmed ID: 21387299 Histamine Restricts Cancer: Nothing to Sneeze At Nature Medicine. Jan, 2011 | Pubmed ID: 21217680 Leukocytes in Mammary Development and Cancer Cold Spring Harbor Perspectives in Biology. Mar, 2011 | Pubmed ID: 21123394 Unimpeded Skin Carcinogenesis in K14-HPV16 Transgenic Mice Deficient for Plasminogen Activator Inhibitor International Journal of Cancer. Jan, 2011 | Pubmed ID: 20232379 The Tumor-immune Microenvironment and Response to Radiation Therapy Journal of Mammary Gland Biology and Neoplasia. Dec, 2010 | Pubmed ID: 21161342 Receptor Tyrosine Kinase Signaling Favors a Protumorigenic State in Breast Cancer Cells by Inhibiting the Adaptive Immune Response Cancer Research. Oct, 2010 | Pubmed ID: 20924104 Macrophage Expression of Hypoxia-inducible Factor-1 Alpha Suppresses T-cell Function and Promotes Tumor Progression Cancer Research. Oct, 2010 | Pubmed ID: 20841473 Interactions Between Lymphocytes and Myeloid Cells Regulate Pro- Versus Anti-tumor Immunity Cancer Metastasis Reviews. Jun, 2010 | Pubmed ID: 20405169 Cancer and Inflammation: Promise for Biologic Therapy Journal of Immunotherapy (Hagerstown, Md. : 1997). May, 2010 | Pubmed ID: 20386472 Stromal Regulación De La Estabilidad De La Embarcación Por MMP14 Y TGFbeta Disease Models & Mechanisms. May-Jun, 2010 | Pubmed ID: 20223936 FcRgamma Activation Regulates Inflammation-associated Squamous Carcinogenesis Cancer Cell. Feb, 2010 | Pubmed ID: 20138013 Lymphocytes in Cancer Development: Polarization Towards Pro-tumor Immunity Cytokine & Growth Factor Reviews. Feb, 2010 | Pubmed ID: 20005150 Respiratory Homeostasis and Exploitation of the Immune System for Lung Cancer Vaccines US Oncology. 2009 | Pubmed ID: 22368692 Imágenes ópticas De La Respuesta Inflamatoria Peri-tumoral En El Cáncer De Mama Journal of Translational Medicine. 2009 | Pubmed ID: 19906309 A Base De Colágeno Modelos Migración Celular in Vitro E in Vivo Seminars in Cell & Developmental Biology. Oct, 2009 | Pubmed ID: 19682592 CD4(+) T Cells Regulate Pulmonary Metastasis of Mammary Carcinomas by Enhancing Protumor Properties of Macrophages Cancer Cell. Aug, 2009 | Pubmed ID: 19647220 Delineating Protease Functions During Cancer Development Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19377975 Development of an Optimized Activatable MMP-14 Targeted SPECT Imaging Probe Bioorganic & Medicinal Chemistry. Jan, 2009 | Pubmed ID: 19109023 Inflaming Gastrointestinal Oncogenic Programming Cancer Cell. Jul, 2008 | Pubmed ID: 18598939 Genetic and Cellular Mechanisms of Oncogenesis Current Opinion in Genetics & Development. Feb, 2008 | Pubmed ID: 18440220 Polarized Immune Responses Differentially Regulate Cancer Development Immunological Reviews. Apr, 2008 | Pubmed ID: 18363999 The Initial Steps of Ovarian Cancer Cell Metastasis Are Mediated by MMP-2 Cleavage of Vitronectin and Fibronectin The Journal of Clinical Investigation. Apr, 2008 | Pubmed ID: 18340378 Immune Cells As Mediators of Solid Tumor Metastasis Cancer Metastasis Reviews. Mar, 2008 | Pubmed ID: 18066650 Tissue Inhibitor of Metalloproteinases-1 Promotes Liver Metastasis by Induction of Hepatocyte Growth Factor Signaling Cancer Research. Sep, 2007 | Pubmed ID: 17875701 Inflammation and Breast Cancer. Balancing Immune Response: Crosstalk Between Adaptive and Innate Immune Cells During Breast Cancer Progression Breast Cancer Research : BCR. 2007 | Pubmed ID: 17705880 Distinctive Features of Angiogenesis and Lymphangiogenesis Determine Their Functionality During De Novo Tumor Development Cancer Research. Jun, 2007 | Pubmed ID: 17545601 Hu / Mu Protin Microarrays De Oligonucleótidos: Dual-especie De Matriz De Perfiles De La Proteasa Y De Expresión Inhibidor De La Proteasa Del Gen En Los Tumores Y De Su Microambiente Molecular Cancer Research : MCR. May, 2007 | Pubmed ID: 17510311 Tipo I El Colágeno Es Un Modificador Genético De La Metaloproteinasa De La Matriz 2 En Desarrollo Esquelético Murino Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jun, 2007 | Pubmed ID: 17440987 IKKalpha at the Crossroads of Inflammation and Metastasis Cell. Apr, 2007 | Pubmed ID: 17418780 Humoral Immunity, Inflammation and Cancer Current Opinion in Immunology. Apr, 2007 | Pubmed ID: 17276050 Immune Cells As Anti-cancer Therapeutic Targets and Tools Journal of Cellular Biochemistry. Jul, 2007 | Pubmed ID: 17265430 Tumor Stroma and Regulation of Cancer Development Annual Review of Pathology. 2006 | Pubmed ID: 18039110 Progresión Tumoral Y La Metástasis De Genética Microambiental Determinantes: Un Taller De La Sección Del Estudio De La NIH De La Progresión Y La Metástasis De Tumor En Honor Del Dr. Martin L. Padarathsingh, 31 De Mayo De 2006, Georgetown, Washington, DC Cancer Biology & Therapy. Dec, 2006 | Pubmed ID: 17224636 Analysis of Immune Cell Infiltrates During Squamous Carcinoma Development The Journal of Investigative Dermatology. Symposium Proceedings. Sep, 2006 | Pubmed ID: 17069009 A Selective Activity-based Probe for the Papain Family Cysteine Protease Dipeptidyl Peptidase I/cathepsin C Journal of the American Chemical Society. May, 2006 | Pubmed ID: 16637611 The Inflammatory Tumor Microenvironment and Its Impact on Cancer Development Contributions to Microbiology. 2006 | Pubmed ID: 16627962 Inflammation, Proteases and Cancer European Journal of Cancer (Oxford, England : 1990). Apr, 2006 | Pubmed ID: 16524717 Paradoxical Roles of the Immune System During Cancer Development Nature Reviews. Cancer. Jan, 2006 | Pubmed ID: 16397525 Three-dimensional Visualization of Blood and Lymphatic Vasculature in Tissue Whole Mounts Using Confocal Microscopy Current Protocols in Cytometry. May, 2005 | Pubmed ID: 18770816 De Novo Carcinogenesis Promoted by Chronic Inflammation is B Lymphocyte Dependent Cancer Cell. May, 2005 | Pubmed ID: 15894262 La Contribución De Los Derivados De Médula ósea Las Células a La Vasculatura Del Tumor En El Neuroblastoma Es La MMP-9 Dependiente Cancer Research. Apr, 2005 | Pubmed ID: 15833851 Soluble Mediators of Inflammation During Tumor Development Advances in Cancer Research. 2005 | Pubmed ID: 15797447 Early Neoplastic Progression is Complement Independent Neoplasia (New York, N.Y.). Nov-Dec, 2004 | Pubmed ID: 15720803 Cancer: an Inflammatory Link Nature. Sep, 2004 | Pubmed ID: 15385993 Matrix Metalloproteinase-2 and -9 Expression Increases in Mycoplasma-infected Airways but is Not Required for Microvascular Remodeling American Journal of Physiology. Lung Cellular and Molecular Physiology. Aug, 2004 | Pubmed ID: 15075248 Stromal Matrix Metalloproteinase-9 Regulates the Vascular Architecture in Neuroblastoma by Promoting Pericyte Recruitment Cancer Research. Mar, 2004 | Pubmed ID: 14996727 TIMP-1 Alters Susceptibility to Carcinogenesis Cancer Research. Feb, 2004 | Pubmed ID: 14871825 The Tumor Microenvironment: a Critical Determinant of Neoplastic Evolution European Journal of Cell Biology. Nov, 2003 | Pubmed ID: 14703010 Immune Enhancement of Skin Carcinogenesis by CD4+ T Cells The Journal of Experimental Medicine. Apr, 2003 | Pubmed ID: 12695493 Epithelial Carcinogenesis: Dynamic Interplay Between Neoplastic Cells and Their Microenvironment Differentiation; Research in Biological Diversity. Dec, 2002 | Pubmed ID: 12492502 Inflammation and Cancer Nature. Dec 19-26, 2002 | Pubmed ID: 12490959 MMP9 Potentiates Pulmonary Metastasis Formation Cancer Cell. Oct, 2002 | Pubmed ID: 12398887 RECKing MMP Function: Implications for Cancer Development Trends in Cell Biology. May, 2002 | Pubmed ID: 12062160 Matrix Metalloproteinase Inhibitors and Cancer: Trials and Tribulations Science (New York, N.Y.). Mar, 2002 | Pubmed ID: 11923519 Procedimientos quirúrgicos y metodología para un modelo murino preclínico Charles E. Gast1, Aubie K. Shaw1,2, Melissa H. Wong1,3, Lisa M. Coussens1,3 1Cell, Developmental & Cancer Biology, Oregon Health & Science University, 2University of Minnesota, 3Knight Cancer Institute, Oregon Health & Science University JoVE 54852 Cancer Research
Procedimientos quirúrgicos y metodología para un modelo murino preclínico Charles E. Gast1, Aubie K. Shaw1,2, Melissa H. Wong1,3, Lisa M. Coussens1,3 1Cell, Developmental & Cancer Biology, Oregon Health & Science University, 2University of Minnesota, 3Knight Cancer Institute, Oregon Health & Science University JoVE 54852 Cancer Research