Louis Tong

Singapore Eye Research Institute

Affiliated withSingapore Eye Research Institute Singapore National Eye Center Duke-NUS Medical School

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JoVE Journal Publications

ArticleTotal : 3	Year
Publication title Cited by 5	2017
Publication title Cited by 9	2017
Publication title Cited by 12	2017

Other Publications

Article	Year
A multiple regression approach to study optical components of myopia in Singapore school children. Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)\| PubMed ID: 11824645	2002
Refractive error and monochromatic aberrations in Singaporean children. Vision research\| PubMed ID: 12127112	2002
Prevalence rates and epidemiological risk factors for astigmatism in Singapore school children. Optometry and vision science : official publication of the American Academy of Optometry\| PubMed ID: 12322931	2002
Sensitivity and specificity of visual acuity screening for refractive errors in school children. Optometry and vision science : official publication of the American Academy of Optometry\| PubMed ID: 12395920	2002
Agreement between Scheimpflug photography and A-scan ultrasonography in anterior segment ocular measurements in children. Optometry and vision science : official publication of the American Academy of Optometry\| PubMed ID: 12858088	2003
Repeatability of ocular blood flow pneumotonometry. Ophthalmology\| PubMed ID: 12917171	2003
Anisometropia in Singapore school children. American journal of ophthalmology\| PubMed ID: 15013870	2004
High rate and changing molecular epidemiology pattern of norovirus infections in sporadic cases and outbreaks of gastroenteritis in Hong Kong. Journal of medical virology\| PubMed ID: 15042657	2004
Viral shedding patterns of coronavirus in patients with probable severe acute respiratory syndrome. Lancet (London, England)\| PubMed ID: 15158632	2004
Optic disk and retinal characteristics in myopic children. American journal of ophthalmology\| PubMed ID: 15234307	2004
Deep anterior lamellar keratoplasty in a patient with descemetocele following gonococcal keratitis. American journal of ophthalmology\| PubMed ID: 15364250	2004
Screening for myopia and refractive errors using LogMAR visual acuity by optometrists and a simplified visual acuity chart by nurses. Optometry and vision science : official publication of the American Academy of Optometry\| PubMed ID: 15365388	2004
Incidence and progression of astigmatism in Singaporean children. Investigative ophthalmology & visual science\| PubMed ID: 15505036	2004
Corneal thickness determination and correlates in Singaporean schoolchildren. Investigative ophthalmology & visual science\| PubMed ID: 15505049	2004
Incidence and progression of myopia in Singaporean school children. Investigative ophthalmology & visual science\| PubMed ID: 15623754	2005
The spin test in latent nystagmus. Archives of ophthalmology (Chicago, Ill. : 1960)\| PubMed ID: 15710844	2005
Prevalence of cataract in rural Indonesia. Ophthalmology\| PubMed ID: 15993241	2005
Expression and regulation of cornified envelope proteins in human corneal epithelium. Investigative ophthalmology & visual science\| PubMed ID: 16639001	2006
Longitudinal study of anisometropia in Singaporean school children. Investigative ophthalmology & visual science\| PubMed ID: 16877388	2006
Targeted inhibition of p57 and p15 blocks transforming growth factor beta-inhibited proliferation of primary cultured human limbal epithelial cells. Molecular vision\| PubMed ID: 16943770	2006
Atropine for the treatment of childhood myopia. Ophthalmology\| PubMed ID: 16996612	2006
Transglutaminase participates in UVB-induced cell death pathways in human corneal epithelial cells. Investigative ophthalmology & visual science\| PubMed ID: 17003418	2006
Stress-activated protein kinase signaling pathways in dry eye and ocular surface disease. The ocular surface\| PubMed ID: 17216108	2005
Heidelberg retinal tomography of optic disc and nerve fiber layer in singapore children: variations with disc tilt and refractive error. Investigative ophthalmology & visual science\| PubMed ID: 17962442	2007
Relationship of retinal vascular caliber with optic disc diameter in children. Investigative ophthalmology & visual science\| PubMed ID: 17962443	2007
Hyperosmolarity-induced cornification of human corneal epithelial cells is regulated by JNK MAPK. Investigative ophthalmology & visual science\| PubMed ID: 18234997	2008
Cornea biomechanical characteristics and their correlates with refractive error in Singaporean children. Investigative ophthalmology & visual science\| PubMed ID: 18469185	2008
Phospholipase D in the human ocular surface and in pterygium. Cornea\| PubMed ID: 18580262	2008
Red-green colour blindness in Singaporean children. Clinical & experimental ophthalmology\| PubMed ID: 18942220	2008
Aspirin and dry eye? Ophthalmology\| PubMed ID: 19118708	2009
Atropine for the treatment of childhood myopia: effect on myopia progression after cessation of atropine. Ophthalmology\| PubMed ID: 19167081	2009
A questionnaire-based assessment of symptoms associated with tear film dysfunction and lid margin disease in an Asian population. Ophthalmic epidemiology\| PubMed ID: 19191179	2009
Calcium-binding S100 protein expression in pterygium. Molecular vision\| PubMed ID: 19223989	2009
Prevalence and risk factors of undercorrected refractive errors among Singaporean Malay adults: the Singapore Malay Eye Study. Investigative ophthalmology & visual science\| PubMed ID: 19264898	2009
Distinct gene subsets in pterygia formation and recurrence: dissecting complex biological phenomenon using genome wide expression data. BMC medical genomics\| PubMed ID: 19272163	2009
Comparison of gene expression profiles of conjunctival cell lines with primary cultured conjunctival epithelial cells and human conjunctival tissue. Gene expression\| PubMed ID: 19630270	2009
Distribution and determinants of ocular biometric parameters in an Asian population: the Singapore Malay eye study. Investigative ophthalmology & visual science\| PubMed ID: 19684013	2010
Identification of tear fluid biomarkers in dry eye syndrome using iTRAQ quantitative proteomics. Journal of proteome research\| PubMed ID: 19705875	2009
Comment on "The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation". Journal of immunology (Baltimore, Md. : 1950)\| PubMed ID: 19767563	2009
Dietary factors, myopia, and axial dimensions in children. Ophthalmology\| PubMed ID: 20079928	2010
Screening for meibomian gland disease: its relation to dry eye subtypes and symptoms in a tertiary referral clinic in singapore. Investigative ophthalmology & visual science\| PubMed ID: 20181848	2010
The use of HRT with and without the aid of disc photographs. Journal of glaucoma\| PubMed ID: 20577099	2011
Hyperosmolarity-mediated mitochondrial dysfunction requires Transglutaminase-2 in human corneal epithelial cells. Journal of cellular physiology\| PubMed ID: 20717931	2011
The nuclear-factor kappaB pathway is activated in pterygium. Investigative ophthalmology & visual science\| PubMed ID: 20811049	2011
Association of tear proteins with Meibomian gland disease and dry eye symptoms. The British journal of ophthalmology\| PubMed ID: 21030416	2011
Aberrant DNA methylation of matrix remodeling and cell adhesion related genes in pterygium. PloS one\| PubMed ID: 21359202	2011
A new method of high-speed cellular protein separation and insight into subcellular compartmentalization of proteins. Analytical and bioanalytical chemistry\| PubMed ID: 21380751	2011
The international workshop on meibomian gland dysfunction: report of the subcommittee on the epidemiology of, and associated risk factors for, MGD. Investigative ophthalmology & visual science\| PubMed ID: 21450917	2011
Comments: acupuncture for treating dry eye: a randomized placebo-controlled trial. Acta ophthalmologica\| PubMed ID: 21470382	2011
Transglutaminases (TGs) in ocular and periocular tissues: effect of muscarinic agents on TGs in scleral fibroblasts. PloS one\| PubMed ID: 21494676	2011
Proteomic profiling of inflammatory signaling molecules in the tears of patients on chronic glaucoma medication. Investigative ophthalmology & visual science\| PubMed ID: 21697136	2011
Myopia-related optic disc and retinal changes in adolescent children from singapore. Ophthalmology\| PubMed ID: 21820741	2011
S100A expression in normal corneal-limbal epithelial cells and ocular surface squamous cell carcinoma tissue. Molecular vision\| PubMed ID: 21897749	2011
Non-hormonal systemic medications and dry eye. The ocular surface\| PubMed ID: 22023816	2011
Meibum lipid composition in Asians with dry eye disease. PloS one\| PubMed ID: 22043274	2011
Focus on molecules: Phospholipase D. Experimental eye research\| PubMed ID: 22138418	2012
Clinical considerations in proinflammatory cytokine profiling of tears from patients with dry eye by means of antibody microarrays. Investigative ophthalmology & visual science\| PubMed ID: 22186423	2011
Involvement of SPARC and MMP-3 in the pathogenesis of human pterygium. Investigative ophthalmology & visual science\| PubMed ID: 22222271	2012
Prevalence and risk factors of meibomian gland dysfunction: the Singapore Malay eye study. Cornea\| PubMed ID: 22236788	2012
Acupuncture has effect on increasing tear break-up time: acupuncture for treating dry eye, a randomized placebo-controlled trial. Acta ophthalmologica\| PubMed ID: 22289193	2012
Correlation between tear matrix metalloproteinases and the Schirmer's test. Investigative ophthalmology & visual science\| PubMed ID: 22441494	2012
Expression, purification and characterization of fourth FAS1 domain of TGFβIp-associated corneal dystrophic mutants. Protein expression and purification\| PubMed ID: 22575305	2012
Cost of dry eye treatment in an Asian clinic setting. PloS one\| PubMed ID: 22701577	2012
Nuclear Factor-κB: central regulator in ocular surface inflammation and diseases. The ocular surface\| PubMed ID: 22814642	2012
Associations of systemic diseases, smoking and contact lens wear with severity of dry eye. Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists)\| PubMed ID: 22958181	2012
Choice of artificial tear formulation for patients with dry eye: where do we start? Cornea\| PubMed ID: 23038032	2012
Lubricant with gelling agent in treating dry eye in adult Chinese patients. Optometry and vision science : official publication of the American Academy of Optometry\| PubMed ID: 23069726	2012
Lipid-containing lubricants for dry eye: a systematic review. Optometry and vision science : official publication of the American Academy of Optometry\| PubMed ID: 23096494	2012
Dry eye. BMJ (Clinical research ed.)\| PubMed ID: 23153839	2012
Application of empirical mode decomposition (emd) for automated detection of epilepsy using EEG signals. International journal of neural systems\| PubMed ID: 23186276	2012
The dry eye disease activity log study. TheScientificWorldJournal\| PubMed ID: 23193384	2012
Knowledge, attitude, and practice of dry eye treatment by institutional Chinese physicians in Singapore. TheScientificWorldJournal\| PubMed ID: 23213306	2012
Detection of meibomian glands and classification of meibography images. Journal of biomedical optics\| PubMed ID: 23224195	2012
Repeatability of a new method for measuring tear evaporation rates. Optometry and vision science : official publication of the American Academy of Optometry\| PubMed ID: 23435224	2013
Molecular mechanism of transglutaminase-2 in corneal epithelial migration and adhesion. Biochimica et biophysica acta\| PubMed ID: 23466867	2013
Comparison of corneal sensitivity, tear function and corneal staining following laser in situ keratomileusis with two femtosecond laser platforms. Clinical ophthalmology (Auckland, N.Z.)\| PubMed ID: 23576858	2013
[The dry eye]. Praxis\| PubMed ID: 23773940	2013
Application of intrinsic time-scale decomposition (ITD) to EEG signals for automated seizure prediction. International journal of neural systems\| PubMed ID: 23924414	2013
Rapid and sensitive profiling of tear wax ester species using high performance liquid chromatography coupled with tandem mass spectrometry. Journal of chromatography. A\| PubMed ID: 23953715	2013
Comparison of gene expression profiles in primary and immortalized human pterygium fibroblast cells. Experimental cell research\| PubMed ID: 24012806	2013
Conjunctivochalasis is the precursor to pterygium. Medical hypotheses\| PubMed ID: 24053977	2013
Rho GTPases and regulation of cell migration and polarization in human corneal epithelial cells. PloS one\| PubMed ID: 24130842	2013
Transglutaminase-2 in cell adhesion: all roads lead to paxillin? Cell adhesion & migration\| PubMed ID: 24193434	2013
Corneal staining characteristics in limited zones compared with whole cornea documentation for the detection of dry eye subtypes. Investigative ophthalmology & visual science\| PubMed ID: 24222306	2013
Extensive characterization of human tear fluid collected using different techniques unravels the presence of novel lipid amphiphiles. Journal of lipid research\| PubMed ID: 24287120	2014
Lipidomic analysis of human tear fluid reveals structure-specific lipid alterations in dry eye syndrome. Journal of lipid research\| PubMed ID: 24287121	2014
S100A proteins as molecular targets in the ocular surface inflammatory diseases. The ocular surface\| PubMed ID: 24439044	2014
Patient acceptability of tear collection in the primary healthcare setting. Optometry and vision science : official publication of the American Academy of Optometry\| PubMed ID: 24492756	2014
Comparative analysis of two femtosecond LASIK platforms using iTRAQ quantitative proteomics. Investigative ophthalmology & visual science\| PubMed ID: 24801511	2014
Evaluation of global differential gene and protein expression in primary Pterygium: S100A8 and S100A9 as possible drivers of a signaling network. PloS one\| PubMed ID: 24825356	2014
Rho protein GTPases and their interactions with NFκB: crossroads of inflammation and matrix biology. Bioscience reports\| PubMed ID: 24877606	2014
The eye: a window of opportunity in rheumatoid arthritis? Nature reviews. Rheumatology\| PubMed ID: 24914693	2014
Specialized moisture retention eyewear for evaporative dry eye. Current eye research\| PubMed ID: 24979390	2015
Longitudinal changes in tear fluid lipidome brought about by eyelid-warming treatment in a cohort of meibomian gland dysfunction. Journal of lipid research\| PubMed ID: 24994912	2014
Decision support system for age-related macular degeneration using discrete wavelet transform. Medical & biological engineering & computing\| PubMed ID: 25112273	2014
Automated diagnosis of Age-related Macular Degeneration using greyscale features from digital fundus images. Computers in biology and medicine\| PubMed ID: 25127409	2014
A Randomized, Controlled Treatment Trial of Eyelid-Warming Therapies in Meibomian Gland Dysfunction. Ophthalmology and therapy\| PubMed ID: 25156975	2014
Lost to follow-up for appointments in a dedicated dry eye clinic. Patient preference and adherence\| PubMed ID: 25336929	2014
Quantitation of 47 human tear proteins using high resolution multiple reaction monitoring (HR-MRM) based-mass spectrometry. Journal of proteomics\| PubMed ID: 25529431	2015
MicroRNA-215 Regulates Fibroblast Function: Insights from a Human Fibrotic Disease. Cell cycle (Georgetown, Tex.)\| PubMed ID: 25565137	2015
A randomised, parallel-group comparison study of diquafosol ophthalmic solution in patients with dry eye in China and Singapore. The British journal of ophthalmology\| PubMed ID: 25631485	2015
Ocular surface disease in posttrabeculectomy/mitomycin C patients. Clinical ophthalmology (Auckland, N.Z.)\| PubMed ID: 25678766	2015
More to stable tears than thickness of the tear film lipid layer. Investigative ophthalmology & visual science\| PubMed ID: 25745077	2015
Barrier function in the ocular surface: from conventional paradigms to new opportunities. The ocular surface\| PubMed ID: 25881994	2015
Application of higher-order spectra for automated grading of diabetic maculopathy. Medical & biological engineering & computing\| PubMed ID: 25894464	2015
Repeatability of tear meniscus evaluation using spectral-domain Cirrus® HD-OCT and time-domain Visante® OCT. Contact lens & anterior eye : the journal of the British Contact Lens Association\| PubMed ID: 25956571	2015
Intra-observer and inter-observer repeatability of ocular surface interferometer in measuring lipid layer thickness. BMC ophthalmology\| PubMed ID: 25975974	2015
Local configuration pattern features for age-related macular degeneration characterization and classification. Computers in biology and medicine\| PubMed ID: 26093788	2015
Dry Eye-Related Visual Blurring and Irritative Symptoms and Their Association with Depression and Anxiety in Eye Clinic Patients. Current eye research\| PubMed ID: 26337790	2016
Application of different imaging modalities for diagnosis of Diabetic Macular Edema: A review. Computers in biology and medicine\| PubMed ID: 26453760	2015
Human tear analysis with miniaturized multiplex cytokine assay on "wall-less" 96-well plate. Molecular vision\| PubMed ID: 26539027	2015
Lipid-Based Therapy for Ocular Surface Inflammation and Disease. Trends in molecular medicine\| PubMed ID: 26596867	2015
Practical issues concerning tear protein assays in dry eye. Eye and vision (London, England)\| PubMed ID: 26605353	2014
Effects of Punctal Occlusion on Clinical Signs and Symptoms and on Tear Cytokine Levels in Patients with Dry Eye. The ocular surface\| PubMed ID: 26774908	2016
Clinical Trial of Thermal Pulsation (LipiFlow) in Meibomian Gland Dysfunction With Preteatment Meibography. Eye & contact lens\| PubMed ID: 26825281	2016
Effects of wearing a daily disposable lens on tear film: a randomised controlled trial. Clinical & experimental optometry\| PubMed ID: 27087449	2016
Longitudinal Changes in Tear Evaporation Rates After Eyelid Warming Therapies in Meibomian Gland Dysfunction. Investigative ophthalmology & visual science\| PubMed ID: 27096755	2016
Lipid-Based Therapy for Ocular Surface Inflammation and Disease. Trends in molecular medicine\| PubMed ID: 27282088	2016
A distinct cytokines profile in tear film of dry eye disease (DED) patients with HIV infection. Cytokine\| PubMed ID: 27585367	2016
Agreement of noninvasive tear break-up time measurement between Tomey RT-7000 Auto Refractor-Keratometer and Oculus Keratograph 5M. Clinical ophthalmology (Auckland, N.Z.)\| PubMed ID: 27695283	2016
In vitro secretomics study of pterygium-derived fibroblasts by iTRAQ-based quantitative proteomics strategy. Experimental eye research\| PubMed ID: 27725197	2016
Need for Animal Models of Meibomian Gland Dysfunction. Ophthalmology and therapy\| PubMed ID: 27837409	2016
Dataset of tear film cytokine levels in dry eye disease (DED) patients with and without HIV infection. Data in brief\| PubMed ID: 27942559	2017
Dataset of longitudinal analysis of tear cytokine levels, CD4, CD8 counts and HIV viral load in dry eye patients with HIV infection. Data in brief\| PubMed ID: 28224132	2017
Zika Virus and Eye. Ocular immunology and inflammation\| PubMed ID: 28318359	2017
Tissue resident memory T cells in the human conjunctiva and immune signatures in human dry eye disease. Scientific reports\| PubMed ID: 28345628	2017
Diagnosis of retinal health in digital fundus images using continuous wavelet transform (CWT) and entropies. Computers in biology and medicine\| PubMed ID: 28351716	2017
Effects of punctal occlusion on global tear proteins in patients with dry eye. The ocular surface\| PubMed ID: 28433820	2017
Incidence and risk factors of symptomatic dry eye disease in Asian Malays from the Singapore Malay Eye Study. The ocular surface\| PubMed ID: 28442380	2017
Expression, Regulation, and Effects of Interleukin-17f in the Human Ocular Surface. Ocular immunology and inflammation\| PubMed ID: 28537453	2017
Ocular lubricant use in medically and surgically treated glaucoma: a retrospective longitudinal analysis. Clinical ophthalmology (Auckland, N.Z.)\| PubMed ID: 28706441	2017
Toll-like receptor 2-mediated NF-kappa B pathway activation in ocular surface epithelial cells. Eye and vision (London, England)\| PubMed ID: 28706958	2017
TFOS DEWS II Diagnostic Methodology report. The ocular surface\| PubMed ID: 28736342	2017
Sodium Hyaluronate in the Treatment of Dry Eye Syndrome: A Systematic Review and Meta-Analysis. Scientific reports\| PubMed ID: 28827614	2017
Dry eye disease and oxidative stress. Acta ophthalmologica\| PubMed ID: 28834388	2017
Review of autoantigens in Sjögren's syndrome: an update. Journal of inflammation research\| PubMed ID: 28848359	2017
The effect of intravitreal injections on dry eye, and proposed management strategies. Clinical ophthalmology (Auckland, N.Z.)\| PubMed ID: 28860698	2017
Persistence of Zika virus in conjunctival fluid of convalescence patients. Scientific reports\| PubMed ID: 28894118	2017
Factors that influence tear meniscus area and conjunctivochalasis: The Singapore Indian eye study. Ophthalmic epidemiology\| PubMed ID: 28910571	2017
Relevance of Lipid-Based Products in the Management of Dry Eye Disease. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics\| PubMed ID: 28956698	2017