Lucy Shapiro

Department of Developmental Biology, Stanford University School of Medicine

Affiliated withStanford University School of Medicine

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 53	2015

Other Publications

Article	Year
Genes directly controlled by CtrA, a master regulator of the Caulobacter cell cycle. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 11930012	2002
Dynamic localization of proteins and DNA during a bacterial cell cycle. Nature reviews. Molecular cell biology\| PubMed ID: 11994737	2002
Control of chromosome replication in caulobacter crescentus. Annual review of microbiology\| PubMed ID: 12142494	2002
A dynamically localized histidine kinase controls the asymmetric distribution of polar pili proteins. The EMBO journal\| PubMed ID: 12198144	2002
DNA methylation affects the cell cycle transcription of the CtrA global regulator in Caulobacter. The EMBO journal\| PubMed ID: 12234936	2002
A signal transduction protein cues proteolytic events critical to Caulobacter cell cycle progression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12237413	2002
Identification of a localization factor for the polar positioning of bacterial structural and regulatory proteins. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12370432	2002
The CtrA response regulator essential for Caulobacter crescentus cell-cycle progression requires a bipartite degradation signal for temporally controlled proteolysis. Journal of molecular biology\| PubMed ID: 12445780	2002
Generating and exploiting polarity in bacteria. Science (New York, N.Y.)\| PubMed ID: 12471245	2002
TmRNA is required for correct timing of DNA replication in Caulobacter crescentus. Journal of bacteriology\| PubMed ID: 12511504	2003
Functions of the CckA histidine kinase in Caulobacter cell cycle control. Molecular microbiology\| PubMed ID: 12603734	2003
tmRNA in Caulobacter crescentus is cell cycle regulated by temporally controlled transcription and RNA degradation. Journal of bacteriology\| PubMed ID: 12618446	2003
Temporal and spatial regulation in prokaryotic cell cycle progression and development. Annual review of biochemistry\| PubMed ID: 12651741	2003
Cell-cycle-regulated expression and subcellular localization of the Caulobacter crescentus SMC chromosome structural protein. Journal of bacteriology\| PubMed ID: 12730166	2003
Polar localization of replicon origins in the multipartite genomes of Agrobacterium tumefaciens and Sinorhizobium meliloti. Journal of bacteriology\| PubMed ID: 12754237	2003
Bacterial cell division spirals into control. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12810947	2003
Fluorescence bleaching reveals asymmetric compartment formation prior to cell division in Caulobacter. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 12824468	2003
A lytic transglycosylase homologue, PleA, is required for the assembly of pili and the flagellum at the Caulobacter crescentus cell pole. Molecular microbiology\| PubMed ID: 12828633	2003
Identification of long intergenic repeat sequences associated with DNA methylation sites in Caulobacter crescentus and other alpha-proteobacteria. Journal of bacteriology\| PubMed ID: 12897020	2003
A bacterial cell-cycle regulatory network operating in time and space. Science (New York, N.Y.)\| PubMed ID: 14512618	2003
Codon usage between genomes is constrained by genome-wide mutational processes. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14990797	2004
Oscillating global regulators control the genetic circuit driving a bacterial cell cycle. Science (New York, N.Y.)\| PubMed ID: 15087506	2004
Recruitment of a cytoplasmic response regulator to the cell pole is linked to its cell cycle-regulated proteolysis. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15123835	2004
An actin-like gene can determine cell polarity in bacteria. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15159537	2004
Rapid and sequential movement of individual chromosomal loci to specific subcellular locations during bacterial DNA replication. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15178755	2004
The topoisomerase IV ParC subunit colocalizes with the Caulobacter replisome and is required for polar localization of replication origins. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15178756	2004
A genetic oscillator and the regulation of cell cycle progression in Caulobacter crescentus. Cell cycle (Georgetown, Tex.)\| PubMed ID: 15467452	2004
Spatial complexity of mechanisms controlling a bacterial cell cycle. Current opinion in microbiology\| PubMed ID: 15556028	2004
A membrane metalloprotease participates in the sequential degradation of a Caulobacter polarity determinant. Molecular microbiology\| PubMed ID: 15686556	2005
MreB actin-mediated segregation of a specific region of a bacterial chromosome. Cell\| PubMed ID: 15707892	2005
An open letter to Elias Zerhouni. Science (New York, N.Y.)\| PubMed ID: 15746409	2005
The structure and function of the bacterial chromosome. Current opinion in genetics & development\| PubMed ID: 15797198	2005
The choreographed dynamics of bacterial chromosomes. Trends in microbiology\| PubMed ID: 15866039	2005
Conserved modular design of an oxygen sensory/signaling network with species-specific output. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 15911751	2005
The bacterial nucleoid: a highly organized and dynamic structure. Journal of cellular biochemistry\| PubMed ID: 15988757	2005
Identification of borinic esters as inhibitors of bacterial cell growth and bacterial methyltransferases, CcrM and MenH. Journal of medicinal chemistry\| PubMed ID: 16279806	2005
DnaA coordinates replication initiation and cell cycle transcription in Caulobacter crescentus. Molecular microbiology\| PubMed ID: 16313620	2005
Two independent spiral structures control cell shape in Caulobacter. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16344481	2005
Cytokinesis signals truncation of the PodJ polarity factor by a cell cycle-regulated protease. The EMBO journal\| PubMed ID: 16395329	2006
DnaA couples DNA replication and the expression of two cell cycle master regulators. The EMBO journal\| PubMed ID: 16395331	2006
The bifunctional FtsK protein mediates chromosome partitioning and cell division in Caulobacter. Journal of bacteriology\| PubMed ID: 16452433	2006
A dynamically localized protease complex and a polar specificity factor control a cell cycle master regulator. Cell\| PubMed ID: 16469700	2006
A phospho-signaling pathway controls the localization and activity of a protease complex critical for bacterial cell cycle progression. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16829582	2006
Single molecules of the bacterial actin MreB undergo directed treadmilling motion in Caulobacter crescentus. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 16829583	2006
MipZ, a spatial regulator coordinating chromosome segregation with cell division in Caulobacter. Cell\| PubMed ID: 16839883	2006
Chromosome organization and segregation in bacteria. Journal of structural biology\| PubMed ID: 16860572	2006
High-throughput identification of transcription start sites, conserved promoter motifs and predicted regulons. Nature biotechnology\| PubMed ID: 17401361	2007
The push and pull of the bacterial cytoskeleton. Trends in cell biology\| PubMed ID: 17434308	2007
An antifungal agent inhibits an aminoacyl-tRNA synthetase by trapping tRNA in the editing site. Science (New York, N.Y.)\| PubMed ID: 17588934	2007
Spatial complexity and control of a bacterial cell cycle. Current opinion in biotechnology\| PubMed ID: 17709236	2007
Caulobacter crescentus as a whole-cell uranium biosensor. Applied and environmental microbiology\| PubMed ID: 17905881	2007
Cell cycle regulation in Caulobacter: location, location, location. Journal of cell science\| PubMed ID: 17928306	2007
A DNA methylation ratchet governs progression through a bacterial cell cycle. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 17942674	2007
A comprehensive set of plasmids for vanillate- and xylose-inducible gene expression in Caulobacter crescentus. Nucleic acids research\| PubMed ID: 17959646	2007
Getting organized--how bacterial cells move proteins and DNA. Nature reviews. Microbiology\| PubMed ID: 18059290	2008
Systems biology of Caulobacter. Annual review of genetics\| PubMed ID: 18076330	2007
Small non-coding RNAs in Caulobacter crescentus. Molecular microbiology\| PubMed ID: 18373523	2008
Architecture and inherent robustness of a bacterial cell-cycle control system. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18685108	2008
SpoT regulates DnaA stability and initiation of DNA replication in carbon-starved Caulobacter crescentus. Journal of bacteriology\| PubMed ID: 18723629	2008
Super-resolution imaging in live Caulobacter crescentus cells using photoswitchable EYFP. Nature methods\| PubMed ID: 18794860	2008
A polymeric protein anchors the chromosomal origin/ParB complex at a bacterial cell pole. Cell\| PubMed ID: 18805088	2008
Caulobacter requires a dedicated mechanism to initiate chromosome segregation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18824683	2008
A bacterial control circuit integrates polar localization and proteolysis of key regulatory proteins with a phospho-signaling cascade. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 18946044	2008
Feedback control of DnaA-mediated replication initiation by replisome-associated HdaA protein in Caulobacter. Journal of bacteriology\| PubMed ID: 19633089	2009
System-level design of bacterial cell cycle control. FEBS letters\| PubMed ID: 19766635	2009
Caulobacter PopZ forms a polar subdomain dictating sequential changes in pole composition and function. Molecular microbiology\| PubMed ID: 20149103	2010
High-throughput identification of protein localization dependency networks. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20176934	2010
Bacterial chromosome organization and segregation. Cold Spring Harbor perspectives in biology\| PubMed ID: 20182613	2010
Cell pole-specific activation of a critical bacterial cell cycle kinase. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20351295	2010
DipM links peptidoglycan remodelling to outer membrane organization in Caulobacter. Molecular microbiology\| PubMed ID: 20497504	2010
Polar remodeling and histidine kinase activation, which is essential for Caulobacter cell cycle progression, are dependent on DNA replication initiation. Journal of bacteriology\| PubMed ID: 20525830	2010
CrfA, a small noncoding RNA regulator of adaptation to carbon starvation in Caulobacter crescentus. Journal of bacteriology\| PubMed ID: 20601471	2010
A spindle-like apparatus guides bacterial chromosome segregation. Nature cell biology\| PubMed ID: 20657594	2010
The caulobacter Tol-Pal complex is essential for outer membrane integrity and the positioning of a polar localization factor. Journal of bacteriology\| PubMed ID: 20693330	2010
Imaging-based identification of a critical regulator of FtsZ protofilament curvature in Caulobacter. Molecular cell\| PubMed ID: 20864042	2010
Superresolution imaging of targeted proteins in fixed and living cells using photoactivatable organic fluorophores. Journal of the American Chemical Society\| PubMed ID: 20936809	2010
Initiating bacterial mitosis: understanding the mechanism of ParA-mediated chromosome segregation. Cell cycle (Georgetown, Tex.)\| PubMed ID: 20948303	2010
An essential transcription factor, SciP, enhances robustness of Caulobacter cell cycle regulation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 20956288	2010
Bacterial polarity. Current opinion in cell biology\| PubMed ID: 21095111	2011
The architecture and conservation pattern of whole-cell control circuitry. Journal of molecular biology\| PubMed ID: 21371478	2011
Super-resolution imaging of the nucleoid-associated protein HU in Caulobacter crescentus. Biophysical journal\| PubMed ID: 21463569	2011
Regulatory response to carbon starvation in Caulobacter crescentus. PloS one\| PubMed ID: 21494595	2011
Assembly of the Caulobacter cell division machine. Molecular microbiology\| PubMed ID: 21542856	2011
Mutations in the nucleotide binding pocket of MreB can alter cell curvature and polar morphology in Caulobacter. Molecular microbiology\| PubMed ID: 21564339	2011
Fifty years after Jacob and Monod: what are the unanswered questions in molecular biology? Molecular cell\| PubMed ID: 21748867	2011
The essential genome of a bacterium. Molecular systems biology\| PubMed ID: 21878915	2011
Exploring protein superstructures and dynamics in live bacterial cells using single-molecule and superresolution imaging. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 21909887	2011
An SMC ATPase mutant disrupts chromosome segregation in Caulobacter. Molecular microbiology\| PubMed ID: 21923769	2011
The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation. Molecular cell\| PubMed ID: 22017872	2011
Three-dimensional superresolution colocalization of intracellular protein superstructures and the cell surface in live Caulobacter crescentus. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 22031697	2011
Structure of the pilus assembly protein TadZ from Eubacterium rectale: implications for polar localization. Molecular microbiology\| PubMed ID: 22211578	2012
Three-dimensional super-resolution imaging of the midplane protein FtsZ in live Caulobacter crescentus cells using astigmatism. Chemphyschem : a European journal of chemical physics and physical chemistry\| PubMed ID: 22262316	2012
Osmolality-dependent relocation of penicillin-binding protein PBP2 to the division site in Caulobacter crescentus. Journal of bacteriology\| PubMed ID: 22505677	2012
Life in a three-dimensional grid. The Journal of biological chemistry\| PubMed ID: 23007401	2012
Chromosome architecture is a key element of bacterial cellular organization. Cellular microbiology\| PubMed ID: 23078580	2013
Caulobacter chromosome in vivo configuration matches model predictions for a supercoiled polymer in a cell-like confinement. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23319648	2013
Quantitative multicolor subdiffraction imaging of bacterial protein ultrastructures in three dimensions. Nano letters\| PubMed ID: 23414562	2013
Retrospective. Francois Jacob (1920-2013). Science (New York, N.Y.)\| PubMed ID: 23704565	2013
Branched signal wiring of an essential bacterial cell-cycle phosphotransfer protein. Structure (London, England : 1993)\| PubMed ID: 23932593	2013
Oligomerization and higher-order assembly contribute to sub-cellular localization of a bacterial scaffold. Molecular microbiology\| PubMed ID: 24102805	2013
Global methylation state at base-pair resolution of the Caulobacter genome throughout the cell cycle. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24218615	2013
The functions of DNA methylation by CcrM in Caulobacter crescentus: a global approach. Nucleic acids research\| PubMed ID: 24398711	2014
Bacterial scaffold directs pole-specific centromere segregation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 24778223	2014
ClpXP and ClpAP proteolytic activity on divisome substrates is differentially regulated following the Caulobacter asymmetric cell division. Molecular microbiology\| PubMed ID: 24989075	2014
The coding and noncoding architecture of the Caulobacter crescentus genome. PLoS genetics\| PubMed ID: 25078267	2014
Replication initiator DnaA binds at the Caulobacter centromere and enables chromosome segregation. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 25349407	2014
Cell fate regulation governed by a repurposed bacterial histidine kinase. PLoS biology\| PubMed ID: 25349992	2014
The global regulatory architecture of transcription during the Caulobacter cell cycle. PLoS genetics\| PubMed ID: 25569173	2015