Manuela M. Santos

Publications

• Oral Iron Supplementation After Antibiotic Exposure Induces a Deleterious Recovery of the Gut Microbiota
  BMC Microbiology. 09, 2021  |   Pubmed ID: 34583649
• Improvement of Colonic Healing and Surgical Recovery with Perioperative Supplementation of Inulin and Galacto-oligosaccharides
  Clinical Nutrition (Edinburgh, Scotland). 06, 2021  |   Pubmed ID: 34130031
• Oligosaccharides Increase the Genotoxic Effect of Colibactin Produced by Pks+ Escherichia Coli Strains
  BMC Cancer. Feb, 2021  |   Pubmed ID: 33596864
• Acute Invariant NKT Cell Activation Triggers an Immune Response That Drives Prominent Changes in Iron Homeostasis
  Scientific Reports. 12, 2020  |   Pubmed ID: 33273556
• T Lymphocyte-derived TNF and IFN-γ Repress HFE Expression in Cancer Cells
  Molecular Immunology. Jun, 2015  |   Pubmed ID: 25700349
• Hfe and Hjv Exhibit Overlapping Functions for Iron Signaling to Hepcidin
  Journal of Molecular Medicine (Berlin, Germany). May, 2015  |   Pubmed ID: 25609138
• The WT Hemochromatosis Protein HFE Inhibits CD8⁺ T-lymphocyte Activation
  European Journal of Immunology. Jun, 2014  |   Pubmed ID: 24643698
• Extraction of High Added Value Biological Compounds from Sardine, Sardine-type Fish and Mackerel Canning Residues--a Review
  Materials Science & Engineering. C, Materials for Biological Applications. Aug, 2013  |   Pubmed ID: 23706190
• Bacterial Cell Wall Constituents Induce Hepcidin Expression in Macrophages Through MyD88 Signaling
  Inflammation. Aug, 2012  |   Pubmed ID: 22544439
• Toll-like Receptor Signal Adaptor Protein MyD88 is Required for Sustained Endotoxin-induced Acute Hypoferremic Response in Mice
  The American Journal of Pathology. Jun, 2012  |   Pubmed ID: 22497726
• Friend of GATA Suppresses the GATA-induced Transcription of Hepcidin in Hepatocytes Through a GATA-regulatory Element in the HAMP Promoter
  Journal of Molecular Endocrinology. Dec, 2011  |   Pubmed ID: 21971825
• Impact of Hemochromatosis Gene (HFE) Mutations on Epithelial Ovarian Cancer Risk and Prognosis
  International Journal of Cancer. Journal International Du Cancer. May, 2011  |   Pubmed ID: 20669231
• Contribution of STAT3 and SMAD4 Pathways to the Regulation of Hepcidin by Opposing Stimuli
  Blood. Apr, 2009  |   Pubmed ID: 19204324
• Is the Iron Donor Lipocalin 2 Implicated in the Pathophysiology of Hereditary Hemochromatosis?
  Hepatology (Baltimore, Md.). Mar, 2009  |   Pubmed ID: 19152427
• Anemia Upregulates Lipocalin 2 in the Liver and Serum
  Blood Cells, Molecules & Diseases. Sep-Oct, 2008  |   Pubmed ID: 18519167
• Repression of Repulsive Guidance Molecule C During Inflammation is Independent of Hfe and Involves Tumor Necrosis Factor-alpha
  The American Journal of Pathology. Feb, 2007  |   Pubmed ID: 17255318
• Exclusion of Mutations in the PRNP, JPH3, TBP, ATN1, CREBBP, POU3F2 and FTL Genes As a Cause of Disease in Portuguese Patients with a Huntington-like Phenotype
  Journal of Human Genetics. 2006  |   Pubmed ID: 16858508
• Distinct Requirements for Hfe in Basal and Induced Hepcidin Levels in Iron Overload and Inflammation
  American Journal of Physiology. Gastrointestinal and Liver Physiology. Aug, 2006  |   Pubmed ID: 16565419
• Gene Expression Profiling in Frataxin Deficient Mice: Microarray Evidence for Significant Expression Changes Without Detectable Neurodegeneration
  Neurobiology of Disease. May, 2006  |   Pubmed ID: 16442805
• Contribution of Hfe Expression in Macrophages to the Regulation of Hepatic Hepcidin Levels and Iron Loading
  Blood. Sep, 2005  |   Pubmed ID: 15914561
• Frataxin Overexpressing Mice
  FEBS Letters. Aug, 2004  |   Pubmed ID: 15304363
• Genomic Structure, Promoter Activity, and Developmental Expression of the Mouse Homologue of the Machado-Joseph Disease (MJD) Gene
  Genomics. Aug, 2004  |   Pubmed ID: 15233999
• Contributions of Beta2-microglobulin-dependent Molecules and Lymphocytes to Iron Regulation: Insights from HfeRag1(-/-) and Beta2mRag1(-/-) Double Knock-out Mice
  Blood. Apr, 2004  |   Pubmed ID: 14656877
• Iron Metabolism in Mice with Partial Frataxin Deficiency
  Cerebellum (London, England). 2003  |   Pubmed ID: 12880182
• Hfe Deficiency Increases Susceptibility to Cardiotoxicity and Exacerbates Changes in Iron Metabolism Induced by Doxorubicin
  Blood. Oct, 2003  |   Pubmed ID: 12805055
• Frataxin Knockin Mouse
  FEBS Letters. Feb, 2002  |   Pubmed ID: 11852098