Melinda K. Duncan

Publications

• ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment
  Cells. Nov, 2023  |   Pubmed ID: 37998373
• The Immediate Early Response of Lens Epithelial Cells to Lens Injury
  Cells. Nov, 2022  |   Pubmed ID: 36359852
• αVβ8 Integrin Targeting to Prevent Posterior Capsular Opacification
  JCI Insight. Nov, 2021  |   Pubmed ID: 34554928
• The Effect of Sex on the Mouse Lens Transcriptome
  Experimental Eye Research. Aug, 2021  |   Pubmed ID: 34146586
• The Aging Mouse Lens Transcriptome
  Experimental Eye Research. Aug, 2021  |   Pubmed ID: 34119483
• A Simple Method for Quantitating Confocal Fluorescent Images
  Biochemistry and Biophysics Reports. Mar, 2021  |   Pubmed ID: 33553685
• Morphometric Analysis of the Lens in Human Aniridia and Mouse Small Eye
  Experimental Eye Research. 02, 2021  |   Pubmed ID: 33248069
• Fibronectin Has Multifunctional Roles in Posterior Capsular Opacification (PCO)
  Matrix Biology : Journal of the International Society for Matrix Biology. Aug, 2020  |   Pubmed ID: 32173580
• A New Transgenic Reporter Line Reveals Wnt-dependent Snai2 Re-expression and Cranial Neural Crest Differentiation in Xenopus
  Scientific Reports. Aug, 2019  |   Pubmed ID: 31371771
• Cataract Surgeon Viewpoints on the Need for Novel Preventative Anti-inflammatory and Anti-posterior Capsular Opacification Therapies
  Current Medical Research and Opinion. Nov, 2019  |   Pubmed ID: 31328581
• Lens Epithelial Cells Initiate an Inflammatory Response Following Cataract Surgery
  Investigative Ophthalmology & Visual Science. Oct, 2018  |   Pubmed ID: 30326070
• Spatiotemporal Dynamics of Canonical Wnt Signaling During Embryonic Eye Development and Posterior Capsular Opacification (PCO)
  Experimental Eye Research. Oct, 2018  |   Pubmed ID: 29932883
• β1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis
  Investigative Ophthalmology & Visual Science. Aug, 2017  |   Pubmed ID: 28763805
• The Molecular Mechanisms Underlying Lens Fiber Elongation
  Experimental Eye Research. Mar, 2017  |   Pubmed ID: 27015931
• Intravitreal Methotrexate Infusion for Proliferative Vitreoretinopathy
  Clinical Ophthalmology (Auckland, N.Z.). 2016  |   Pubmed ID: 27698550
• β1-integrin Controls Cell Fate Specification in Early Lens Development
  Differentiation; Research in Biological Diversity. 2016  |   Pubmed ID: 27596755
• Prox1 and Fibroblast Growth Factor Receptors Form a Novel Regulatory Loop Controlling Lens Fiber Differentiation and Gene Expression
  Development (Cambridge, England). Jan, 2016  |   Pubmed ID: 26657765
• Unfolded-protein Response-associated Stabilization of P27(Cdkn1b) Interferes with Lens Fiber Cell Denucleation, Leading to Cataract
  FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Mar, 2016  |   Pubmed ID: 26590164
• Development of Novel Filtering Criteria to Analyze RNA-sequencing Data Obtained from the Murine Ocular Lens During Embryogenesis
  Genomics Data. Dec, 2014  |   Pubmed ID: 25478318
• The Zeb Proteins δEF1 and Sip1 May Have Distinct Functions in Lens Cells Following Cataract Surgery
  Investigative Ophthalmology & Visual Science. Jul, 2014  |   Pubmed ID: 25082886
• Beta-1 Integrin is Important for the Structural Maintenance and Homeostasis of Differentiating Fiber Cells
  The International Journal of Biochemistry & Cell Biology. May, 2014  |   Pubmed ID: 24607497
• Lens Extrusion from Laminin Alpha 1 Mutant Zebrafish
  TheScientificWorldJournal. 2014  |   Pubmed ID: 24526906
• The Roles of αV Integrins in Lens EMT and Posterior Capsular Opacification
  Journal of Cellular and Molecular Medicine. Apr, 2014  |   Pubmed ID: 24495224
• Loss of Sip1 Leads to Migration Defects and Retention of Ectodermal Markers During Lens Development
  Mechanisms of Development. Oct, 2013  |   Pubmed ID: 24161570
• Junctional Adhesion Molecule-A Regulates Vascular Endothelial Growth Factor Receptor-2 Signaling-dependent Mouse Corneal Wound Healing
  PloS One. 2013  |   Pubmed ID: 23667656
• The Unfolded Protein Response is Activated in Connexin 50 Mutant Mouse Lenses
  Experimental Eye Research. Sep, 2012  |   Pubmed ID: 22713599
• AV Integrins and TGF-β-induced EMT: a Circle of Regulation
  Journal of Cellular and Molecular Medicine. Mar, 2012  |   Pubmed ID: 21883891
• Focus on Molecules: Smad Interacting Protein 1 (Sip1, ZEB2, ZFHX1B)
  Experimental Eye Research. Aug, 2012  |   Pubmed ID: 20868684
• Development. A New Focus on RNA in the Lens
  Science (New York, N.Y.). Mar, 2011  |   Pubmed ID: 21436425
• Expression of βA3/A1-crystallin in the Developing and Adult Rat Eye
  Journal of Molecular Histology. Feb, 2011  |   Pubmed ID: 21203897
• Unfolded Protein Response (UPR) is Activated During Normal Lens Development
  Gene Expression Patterns : GEP. 2011  |   Pubmed ID: 21044701
• Characterizing Molecular Diffusion in the Lens Capsule
  Matrix Biology : Journal of the International Society for Matrix Biology. Apr, 2010  |   Pubmed ID: 20026402
• CD44 Expression is Developmentally Regulated in the Mouse Lens and Increases in the Lens Epithelium After Injury
  Differentiation; Research in Biological Diversity. Feb, 2010  |   Pubmed ID: 19853364
• Abnormal Expression of Collagen IV in Lens Activates Unfolded Protein Response Resulting in Cataract
  The Journal of Biological Chemistry. Dec, 2009  |   Pubmed ID: 19858219
• The Lens Capsule
  Experimental Eye Research. Feb, 2009  |   Pubmed ID: 18773892
• PCNA Interacts with Prox1 and Represses Its Transcriptional Activity
  Molecular Vision. 2008  |   Pubmed ID: 19023449
• Contributions of Mouse Genetic Background and Age on Anterior Lens Capsule Thickness
  Anatomical Record (Hoboken, N.J. : 2007). Dec, 2008  |   Pubmed ID: 18951502
• Differential Expression of the HMGN Family of Chromatin Proteins During Ocular Development
  Gene Expression Patterns : GEP. Jul, 2008  |   Pubmed ID: 18502697
• Dual Roles for Prox1 in the Regulation of the Chicken BetaB1-crystallin Promoter
  Investigative Ophthalmology & Visual Science. Apr, 2008  |   Pubmed ID: 18385074
• Attenuation of Junctional Adhesion Molecule-A is a Contributing Factor for Breast Cancer Cell Invasion
  Cancer Research. Apr, 2008  |   Pubmed ID: 18381425
• Genetic and Epigenetic Mechanisms of Gene Regulation During Lens Development
  Progress in Retinal and Eye Research. Nov, 2007  |   Pubmed ID: 17905638
• Conditional Deletion of Beta1-integrin from the Developing Lens Leads to Loss of the Lens Epithelial Phenotype
  Developmental Biology. Jun, 2007  |   Pubmed ID: 17493607
• Subfertility in Mice Harboring a Mutation in BetaB2-crystallin
  Molecular Vision. Mar, 2007  |   Pubmed ID: 17392687
• Deletion of JAM-A Causes Morphological Defects in the Corneal Epithelium
  The International Journal of Biochemistry & Cell Biology. 2007  |   Pubmed ID: 17118692
• Inbred FVB/N Mice Are Mutant at the Cp49/Bfsp2 Locus and Lack Beaded Filament Proteins in the Lens
  Investigative Ophthalmology & Visual Science. Nov, 2006  |   Pubmed ID: 17065509
• Regulation of AlphaA-crystallin Via Pax6, C-Maf, CREB and a Broad Domain of Lens-specific Chromatin
  The EMBO Journal. May, 2006  |   Pubmed ID: 16675956
• Production of Monoclonal Antibodies Against Prox1
  Hybridoma (2005). Feb, 2006  |   Pubmed ID: 16475879
• Expression of Tissue Plasminogen Activator During Eye Development
  Experimental Eye Research. Jul, 2005  |   Pubmed ID: 15978259
• JAM-A Expression During Embryonic Development
  Developmental Dynamics : an Official Publication of the American Association of Anatomists. Aug, 2005  |   Pubmed ID: 15977176
• Palm is Expressed in Both Developing and Adult Mouse Lens and Retina
  BMC Ophthalmology. Jun, 2005  |   Pubmed ID: 15969763
• Ectopic Pax6 Expression Disturbs Lens Fiber Cell Differentiation
  Investigative Ophthalmology & Visual Science. Oct, 2004  |   Pubmed ID: 15452066
• OptiRNAi, an RNAi Design Tool
  Computer Methods and Programs in Biomedicine. Jul, 2004  |   Pubmed ID: 15158049
• Chromosomal Proteins HMGN3a and HMGN3b Regulate the Expression of Glycine Transporter 1
  Molecular and Cellular Biology. May, 2004  |   Pubmed ID: 15082770
• Developmental Expression of Pop1/Bves
  The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Mar, 2004  |   Pubmed ID: 14966204
• Mafs, Prox1, and Pax6 Can Regulate Chicken BetaB1-crystallin Gene Expression
  The Journal of Biological Chemistry. Mar, 2004  |   Pubmed ID: 14707122
• Protein Expression Patterns for Ubiquitous and Tissue Specific Calpains in the Developing Mouse Lens
  Experimental Eye Research. Apr, 2003  |   Pubmed ID: 12634108
• A Comparative CDNA Microarray Analysis Reveals a Spectrum of Genes Regulated by Pax6 in Mouse Lens
  Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Dec, 2002  |   Pubmed ID: 12485166
• Collagen IV in the Developing Lens Capsule
  Matrix Biology : Journal of the International Society for Matrix Biology. Aug, 2002  |   Pubmed ID: 12225806
• General Utility of the Chicken BetaB1-crystallin Promoter to Drive Protein Expression in Lens Fiber Cells of Transgenic Mice
  Transgenic Research. Aug, 2002  |   Pubmed ID: 12212842
• Prox1 is Differentially Localized During Lens Development
  Mechanisms of Development. Mar, 2002  |   Pubmed ID: 11850194
• Overexpression of PAX6(5a) in Lens Fiber Cells Results in Cataract and Upregulation of (alpha)5(beta)1 Integrin Expression
  Journal of Cell Science. Sep, 2000  |   Pubmed ID: 10954416
• Truncated Forms of Pax-6 Disrupt Lens Morphology in Transgenic Mice
  Investigative Ophthalmology & Visual Science. Feb, 2000  |   Pubmed ID: 10670477
• Dual Roles for Pax-6: a Transcriptional Repressor of Lens Fiber Cell-specific Beta-crystallin Genes
  Molecular and Cellular Biology. Sep, 1998  |   Pubmed ID: 9710641