Melinda Wuest

Department of Oncology, University of Alberta

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 3	2020

Other Publications

Article	Year
Biodistribution and uptake of 3'-deoxy-3'-fluorothymidine in ENT1-knockout mice and in an ENT1-knockdown tumor model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine\| PubMed ID: 20720035	2010
Synthesis of hypoxia imaging agent 1-(5-deoxy-5-fluoro-α-D-arabinofuranosyl)-2-nitroimidazole using microfluidic technology. Nuclear medicine and biology\| PubMed ID: 21315279	2011
The muscarinic receptor antagonist propiverine exhibits α(1)-adrenoceptor antagonism in human prostate and porcine trigonum. World journal of urology\| PubMed ID: 21336600	2011
Radiopharmacological evaluation of 6-deoxy-6-[18F]fluoro-D-fructose as a radiotracer for PET imaging of GLUT5 in breast cancer. Nuclear medicine and biology\| PubMed ID: 21531283	2011
Copper-free click chemistry with the short-lived positron emitter fluorine-18. Organic & biomolecular chemistry\| PubMed ID: 21938294	2011
Microfluidic technology: an economical and versatile approach for the synthesis of O-(2-[18F]fluoroethyl)-L-tyrosine ([18F]FET). Bioorganic & medicinal chemistry letters\| PubMed ID: 22342141	2012
Synthesis and evaluation of fluorobenzoylated di- and tripeptides as inhibitors of cyclooxygenase-2 (COX-2). Bioorganic & medicinal chemistry\| PubMed ID: 22386983	2012
In vitro and in vivo evaluation of [(18)F]F-GAZ, a novel oxygen-mimetic azomycin-glucose conjugate, for imaging hypoxic tumor. Cancer biotherapy & radiopharmaceuticals\| PubMed ID: 22746267	2012
Comparative functional evaluation of immunocompetent mouse breast cancer models established from PyMT-tumors using small animal PET with [(18)F]FDG and [(18)F]FLT. American journal of nuclear medicine and molecular imaging\| PubMed ID: 23133804	2012
Synthesis and evaluation of an 18F-labelled norbornene derivative for copper-free click chemistry reactions. Organic & biomolecular chemistry\| PubMed ID: 23640655	2013
Synthesis, characterisation and evaluation of a novel copper-64 complex with selective uptake in EMT-6 cells under hypoxic conditions. Dalton transactions (Cambridge, England : 2003)\| PubMed ID: 23838751	2013
Synthesis and radiopharmacological evaluation of a high-affinity and metabolically stabilized 18F-labeled bombesin analogue for molecular imaging of gastrin-releasing peptide receptor-expres... Nuclear medicine and biology\| PubMed ID: 23969085	2013
Synthesis of three 18F-labelled cyclooxygenase-2 (COX-2) inhibitors based on a pyrimidine scaffold. Organic & biomolecular chemistry\| PubMed ID: 24145766	2013
Positron emission tomography radiotracers for imaging hypoxia. Journal of labelled compounds & radiopharmaceuticals\| PubMed ID: 24285331	2013
Automated synthesis and dosimetry of 6-deoxy-6-[(18)F]fluoro-D-fructose (6-[(18)F]FDF): a radiotracer for imaging of GLUT5 in breast cancer. American journal of nuclear medicine and molecular imaging\| PubMed ID: 24795839	2014
Synthesis and evaluation of 2-amino-5-(4-[(18)F]fluorophenyl)pent-4-ynoic acid ([(18)F]FPhPA): a novel (18)F-labeled amino acid for oncologic PET imaging. Nuclear medicine and biology\| PubMed ID: 24993371	2014
Rerouting the metabolic pathway of (18)F-labeled peptides: the influence of prosthetic groups. Bioconjugate chemistry\| PubMed ID: 25572982	2015
Erratum: Automated synthesis and dosimetry of 6-deoxy-6-[(18)F]fluoro-D-fructose (6-[(18)F]FDF): a radiotracer for imaging of GLUT5 in breast cancer. American journal of nuclear medicine and molecular imaging\| PubMed ID: 25625031	2015
Detecting functional changes with [(18)F]FAZA in a renal cell carcinoma mouse model following sunitinib therapy. EJNMMI research\| PubMed ID: 26116107	2014
Immuno-PET of epithelial ovarian cancer: harnessing the potential of CA125 for non-invasive imaging. EJNMMI research\| PubMed ID: 26116121	2014
Radiopharmacological evaluation of (18)F-labeled phosphatidylserine-binding peptides for molecular imaging of apoptosis. Nuclear medicine and biology\| PubMed ID: 26205076	2015
Targeting lysyl oxidase for molecular imaging in breast cancer. Breast cancer research : BCR\| PubMed ID: 26265048	2015
Design, Synthesis, and Evaluation of an (18)F-Labeled Radiotracer Based on Celecoxib-NBD for Positron Emission Tomography (PET) Imaging of Cyclooxygenase-2 (COX-2). ChemMedChem\| PubMed ID: 26287271	2015
Metabolically Stabilized (68)Ga-NOTA-Bombesin for PET Imaging of Prostate Cancer and Influence of Protease Inhibitor Phosphoramidon. Molecular pharmaceutics\| PubMed ID: 26973098	2016
PET imaging of cyclooxygenase-2 (COX-2) in a pre-clinical colorectal cancer model. EJNMMI research\| PubMed ID: 27112768	2016
Automated synthesis of [(18)F]DCFPyL via direct radiofluorination and validation in preclinical prostate cancer models. EJNMMI research\| PubMed ID: 27142881	2016
Synthesis and pre-clinical evaluation of an (18)F-labeled single-chain antibody fragment for PET imaging of epithelial ovarian cancer. American journal of nuclear medicine and molecular imaging\| PubMed ID: 27508105	2016
Targeting Phosphatidylserine with a Cu-Labeled Peptide for Molecular Imaging of Apoptosis. Molecular pharmaceutics\| PubMed ID: 27608290	2016
In situ click chemistry generation of cyclooxygenase-2 inhibitors. Nature communications\| PubMed ID: 28232747	2017
Proteomic characterization of EL4 lymphoma-derived tumors upon chemotherapy treatment reveals potential roles for lysosomes and caspase-6 during tumor cell death in vivo. Proteomics\| PubMed ID: 28508578	2017
Targeting Prostate-Specific Membrane Antigen (PSMA) with F-18-Labeled Compounds: the Influence of Prosthetic Groups on Tumor Uptake and Clearance Profile. Molecular imaging and biology\| PubMed ID: 28639122	2017
Molecular Imaging of GLUT1 and GLUT5 in Breast Cancer: A Multitracer Positron Emission Tomography Imaging Study in Mice. Molecular pharmacology\| PubMed ID: 29142019	2018
F-Radiolabeling and In Vivo Analysis of SiFA-Derivatized Polymeric Core-Shell Nanoparticles. Bioconjugate chemistry\| PubMed ID: 29202229	2018
Molecular imaging of platelet-derived growth factor receptor-alpha (PDGFRα) in papillary thyroid cancer using immuno-PET. Nuclear medicine and biology\| PubMed ID: 29367096	2018
Positron Emission Tomography (PET) and Pharmacokinetics: Classical Blood Sampling Versus Image-Derived Analysis of [18F]FAZA and [18F]FDG in a Murine Tumor Bearing Model. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques\| PubMed ID: 29702045	2018
Impact of structural alterations on the radiopharmacological profile of F-labeled pyrimidines as cyclooxygenase-2 (COX-2) imaging agents. Nuclear medicine and biology\| PubMed ID: 29800798	2018
Expression and function of hexose transporters GLUT1, GLUT2, and GLUT5 in breast cancer-effects of hypoxia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 29913554	2018
Targeting phosphatidylserine for radionuclide-based molecular imaging of apoptosis. Apoptosis : an international journal on programmed cell death\| PubMed ID: 30684144	2019
Inhibition of Autotaxin with GLPG1690 Increases the Efficacy of Radiotherapy and Chemotherapy in a Mouse Model of Breast Cancer. Molecular cancer therapeutics\| PubMed ID: 31548293	2020
Effect of hypoxia on human equilibrative nucleoside transporters hENT1 and hENT2 in breast cancer. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 31601121	2019
Repeated Fractions of X-Radiation to the Breast Fat Pads of Mice Augment Activation of the Autotaxin-Lysophosphatidate-Inflammatory Cycle. Cancers\| PubMed ID: 31752313	2019
Radiosynthesis and Biological Evaluation of [F]Triacoxib: A New Radiotracer for PET Imaging of COX-2. Molecular pharmaceutics\| PubMed ID: 31816246	2020
Comparison of scandium-44 g with other PET radionuclides in pre-clinical PET phantom imaging. EJNMMI physics\| PubMed ID: 31832809	2019
Radiometal-Containing Aryl Diazonium Salts for Chemoselective Bioconjugation of Tyrosine Residues. ACS omega\| PubMed ID: 31891090	2019