Mikko Airavaara

Publications

• Mitoxantrone, Pixantrone and Mitoxantrone (2-hydroxyethyl)piperazine Are Toll-like Receptor 4 Antagonists, Inhibit NF-κB Activation, and Decrease TNF-alpha Secretion in Primary Microglia
  European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences. Jul, 2020  |   Pubmed ID: 32730846
• Molecular Profile of the Rat Peri-infarct Region Four Days After Stroke: Study with MANF
  Experimental Neurology. Jul, 2020  |   Pubmed ID: 32229226
• Back and to the Future: From Neurotoxin-Induced to Human Parkinson's Disease Models
  Current Protocols in Neuroscience. Mar, 2020  |   Pubmed ID: 32049438
• MANF Ablation Causes Prolonged Activation of the UPR Without Neurodegeneration in the Mouse Midbrain Dopamine System
  ENeuro. Jan/Feb, 2020  |   Pubmed ID: 32005751
• Cerebral Dopamine Neurotrophic Factor-deficiency Leads to Degeneration of Enteric Neurons and Altered Brain Dopamine Neuronal Function in Mice
  Neurobiology of Disease. 02, 2020  |   Pubmed ID: 31783118
• Engineered Antibody-functionalized Porous Silicon Nanoparticles for Therapeutic Targeting of Pro-survival Pathway in Endogenous Neuroblasts After Stroke
  Biomaterials. 01, 2020  |   Pubmed ID: 31670035
• Neuronal Activation Stimulates Cytomegalovirus Promoter-Driven Transgene Expression
  Molecular Therapy. Methods & Clinical Development. Sep, 2019  |   Pubmed ID: 31380464
• Cerebral Dopamine Neurotrophic Factor Diffuses Around the Brainstem and Does Not Undergo Anterograde Transport After Injection to the Substantia Nigra
  Frontiers in Neuroscience. 2019  |   Pubmed ID: 31244598
• Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and Injury
  Frontiers in Physiology. 2019  |   Pubmed ID: 31105589
• Neuroprotective and Reparative Effects of Endoplasmic Reticulum Luminal Proteins - Mesencephalic Astrocyte-derived Neurotrophic Factor and Cerebral Dopamine Neurotrophic Factor
  Croatian Medical Journal. Apr, 2019  |   Pubmed ID: 31044581
• Secondary Pathology of the Thalamus After Focal Cortical Stroke in Rats is Not Associated with Thermal or Mechanical Hypersensitivity and is Not Alleviated by Intra-Thalamic Post-Stroke Delivery of Recombinant CDNF or MANF
  Cell Transplantation. 04, 2019  |   Pubmed ID: 31037983
• Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats
  Neuron. 04, 2019  |   Pubmed ID: 30792150
• Downregulation of Tyrosine Hydroxylase Phenotype After AAV Injection Above Substantia Nigra: Caution in Experimental Models of Parkinson's Disease
  Journal of Neuroscience Research. 03, 2019  |   Pubmed ID: 30548446
• Implementation of Deep Neural Networks to Count Dopamine Neurons in Substantia Nigra
  The European Journal of Neuroscience. 09, 2018  |   Pubmed ID: 30144349
• Pre-α-pro-GDNF and Pre-β-pro-GDNF Isoforms Are Neuroprotective in the 6-hydroxydopamine Rat Model of Parkinson's Disease
  Frontiers in Neurology. 2018  |   Pubmed ID: 29973907
• Poststroke Delivery of MANF Promotes Functional Recovery in Rats
  Science Advances. 05, 2018  |   Pubmed ID: 29806020
• Post-stroke Intranasal (+)-Naloxone Delivery Reduces Microglial Activation and Improves Behavioral Recovery from Ischemic Injury
  ENeuro. Mar-Apr, 2018  |   Pubmed ID: 29766045
• Synthesis of 7β-hydroxy-8-ketone Opioid Derivatives with Antagonist Activity at Mu- and Delta-opioid Receptors
  European Journal of Medicinal Chemistry. May, 2018  |   Pubmed ID: 29649744
• Towards Developing a Model to Study Alcohol Drinking and Craving in Female Mice Housed in Automated Cages
  Behavioural Brain Research. 10, 2018  |   Pubmed ID: 29572104
• The κ-opioid Receptor Antagonist JDTic Decreases Ethanol Intake in Alcohol-preferring AA Rats
  Psychopharmacology. 05, 2018  |   Pubmed ID: 29492614
• Differential Spinal and Supraspinal Activation of Glia in a Rat Model of Morphine Tolerance
  Neuroscience. 04, 2018  |   Pubmed ID: 29421434
• Combination of CDNF and Deep Brain Stimulation Decreases Neurological Deficits in Late-stage Model Parkinson's Disease
  Neuroscience. 03, 2018  |   Pubmed ID: 29408408
• MANF Promotes Differentiation and Migration of Neural Progenitor Cells with Potential Neural Regenerative Effects in Stroke
  Molecular Therapy : the Journal of the American Society of Gene Therapy. 01, 2018  |   Pubmed ID: 29050872
• Development and Plasticity of Meningeal Lymphatic Vessels
  The Journal of Experimental Medicine. Dec, 2017  |   Pubmed ID: 29141865
• MANF Is Essential for Neurite Extension and Neuronal Migration in the Developing Cortex
  ENeuro. Sep-Oct, 2017  |   Pubmed ID: 29082311
• Multifunctional Nanotube-Mucoadhesive Poly(methyl Vinyl Ether-co-maleic Acid)@Hydroxypropyl Methylcellulose Acetate Succinate Composite for Site-Specific Oral Drug Delivery
  Advanced Healthcare Materials. Oct, 2017  |   Pubmed ID: 28714596
• 9-cis Retinoic Acid Induces Neurorepair in Stroke Brain
  Scientific Reports. 07, 2017  |   Pubmed ID: 28674431
• Nigral Injection of a Proteasomal Inhibitor, Lactacystin, Induces Widespread Glial Cell Activation and Shows Various Phenotypes of Parkinson's Disease in Young and Adult Mouse
  Experimental Brain Research. 07, 2017  |   Pubmed ID: 28439627
• Intrastriatally Infused Exogenous CDNF Is Endocytosed and Retrogradely Transported to Substantia Nigra
  ENeuro. Jan-Feb, 2017  |   Pubmed ID: 28275710
• AAV Vector-Mediated Gene Delivery to Substantia Nigra Dopamine Neurons: Implications for Gene Therapy and Disease Models
  Genes. Feb, 2017  |   Pubmed ID: 28208742
• Role of Microglia in Ischemic Focal Stroke and Recovery: Focus on Toll-like Receptors
  Progress in Neuro-psychopharmacology & Biological Psychiatry. 10, 2017  |   Pubmed ID: 27389423
• Update of Neurotrophic Factors in Neurobiology of Addiction and Future Directions
  Neurobiology of Disease. 01, 2017  |   Pubmed ID: 27189755
• Accumbal μ-Opioid Receptors Modulate Ethanol Intake in Alcohol-Preferring Alko Alcohol Rats
  Alcoholism, Clinical and Experimental Research. 10, 2016  |   Pubmed ID: 27508965
• Developing Therapeutically More Efficient Neurturin Variants for Treatment of Parkinson's Disease
  Neurobiology of Disease. Dec, 2016  |   Pubmed ID: 27425888
• Oral Hypoglycaemic Effect of GLP-1 and DPP4 Inhibitor Based Nanocomposites in a Diabetic Animal Model
  Journal of Controlled Release : Official Journal of the Controlled Release Society. 06, 2016  |   Pubmed ID: 27091697
• Characterization of a New Low-dose 6-hydroxydopamine Model of Parkinson's Disease in Rat
  Journal of Neuroscience Research. Apr, 2016  |   Pubmed ID: 26762168
• Therapeutic Potential of the Endoplasmic Reticulum Located and Secreted CDNF/MANF Family of Neurotrophic Factors in Parkinson's Disease
  FEBS Letters. Dec, 2015  |   Pubmed ID: 26450777
• Prospects of Neurotrophic Factors for Parkinson's Disease: Comparison of Protein and Gene Therapy
  Human Gene Therapy. Aug, 2015  |   Pubmed ID: 26176331
• AAV-mediated Targeting of Gene Expression to the Peri-infarct Region in Rat Cortical Stroke Model
  Journal of Neuroscience Methods. Oct, 2014  |   Pubmed ID: 25152446
• Short-term Preoperative Dietary Restriction is Neuroprotective in a Rat Focal Stroke Model
  PloS One. 2014  |   Pubmed ID: 24705386
• Local Administration of AAV-BDNF to Subventricular Zone Induces Functional Recovery in Stroke Rats
  PloS One. 2013  |   Pubmed ID: 24312581
• Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Secretion and Cell Surface Binding Are Modulated by KDEL Receptors
  The Journal of Biological Chemistry. Feb, 2013  |   Pubmed ID: 23255601
• Neurorestoration
  Parkinsonism & Related Disorders. Jan, 2012  |   Pubmed ID: 22166416
• CDNF Protects the Nigrostriatal Dopamine System and Promotes Recovery After MPTP Treatment in Mice
  Cell Transplantation. 2012  |   Pubmed ID: 21943517
• WITHDRAWN: Neurorestoration
  Parkinsonism & Related Disorders. Sep, 2011  |   Pubmed ID: 21924941
• Chronic Nicotine Modifies the Effects of Morphine on Extracellular Striatal Dopamine and Ventral Tegmental GABA
  Journal of Neurochemistry. Nov, 2008  |   Pubmed ID: 18786163
• Characterization of the Striatal Dopaminergic Neurotransmission in MEN2B Mice with Elevated Cerebral Tissue Dopamine
  Journal of Neurochemistry. Jun, 2008  |   Pubmed ID: 18248620
• Constitutive Ret Activity in Knock-in Multiple Endocrine Neoplasia Type B Mice Induces Profound Elevation of Brain Dopamine Concentration Via Enhanced Synthesis and Increases the Number of TH-positive Cells in the Substantia Nigra
  The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. May, 2007  |   Pubmed ID: 17475787
• Effects of Repeated Morphine on Locomotion, Place Preference and Dopamine in Heterozygous Glial Cell Line-derived Neurotrophic Factor Knockout Mice
  Genes, Brain, and Behavior. Apr, 2007  |   Pubmed ID: 16879618
• In Heterozygous GDNF Knockout Mice the Response of Striatal Dopaminergic System to Acute Morphine is Altered
  Synapse (New York, N.Y.). May, 2006  |   Pubmed ID: 16437537
• Increased Extracellular Dopamine Concentrations and FosB/DeltaFosB Expression in Striatal Brain Areas of Heterozygous GDNF Knockout Mice
  The European Journal of Neuroscience. Nov, 2004  |   Pubmed ID: 15525275