Nadia Rosenthal

National Heart and Lung Institute, Imperial College London

Affiliated withImperial College London Monash University

Research Area

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JoVE Journal Publications

ArticleTotal : 1	Year
Publication title Cited by 9	2014

Other Publications

Article	Year
Different modes of hypertrophy in skeletal muscle fibers. The Journal of cell biology\| PubMed ID: 11839766	2002
Targeted deletion of the MLC1f/3f downstream enhancer results in precocious MLC expression and mesoderm ablation. Developmental biology\| PubMed ID: 11884037	2002
Muscle-specific expression of insulin-like growth factor I counters muscle decline in mdx mice. The Journal of cell biology\| PubMed ID: 11927606	2002
The role of stem cells in skeletal and cardiac muscle repair. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society\| PubMed ID: 11967271	2002
Gene therapy for cardiac cachexia? International journal of cardiology\| PubMed ID: 12163223	2002
Taking stock of our models: the function and future of stock centres. Nature reviews. Genetics\| PubMed ID: 12209145	2002
Machinations of the marrow. The Journal of clinical investigation\| PubMed ID: 12511584	2003
Normal female sexual development requires neuregulin-erbB receptor signaling in hypothalamic astrocytes. The Journal of neuroscience : the official journal of the Society for Neuroscience\| PubMed ID: 12514220	2003
Prometheus's vulture and the stem-cell promise. The New England journal of medicine\| PubMed ID: 12867611	2003
Developmental basis of evolutionary digit loss in the Australian lizard Hemiergis. Journal of experimental zoology. Part B, Molecular and developmental evolution\| PubMed ID: 12955843	2003
A caudorostral wave of RALDH2 conveys anteroposterior information to the cardiac field. Development (Cambridge, England)\| PubMed ID: 13129847	2003
Stem cell-mediated muscle regeneration is enhanced by local isoform of insulin-like growth factor 1. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 14745025	2004
The stem cell challenge. Scientific American\| PubMed ID: 15195398	2004
The European dimension for the mouse genome mutagenesis program. Nature genetics\| PubMed ID: 15340424	2004
Targeted expression of insulin-like growth factor-I reduces early myofiber necrosis in dystrophic mdx mice. Molecular therapy : the journal of the American Society of Gene Therapy\| PubMed ID: 15509501	2004
Human hepatocytes in mice receiving pre-immune injection with human cord blood cells. Biochemical and biophysical research communications\| PubMed ID: 15567153	2005
Muscle-specific expression of IGF-1 blocks angiotensin II-induced skeletal muscle wasting. The Journal of clinical investigation\| PubMed ID: 15650772	2005
Muscle expression of a local Igf-1 isoform protects motor neurons in an ALS mouse model. The Journal of cell biology\| PubMed ID: 15657392	2005
Reconciling data from transgenic mice that overexpress IGF-I specifically in skeletal muscle. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society\| PubMed ID: 15701567	2005
Insulin-like growth factor I-mediated skeletal muscle hypertrophy is characterized by increased mTOR-p70S6K signaling without increased Akt phosphorylation. Journal of investigative medicine : the official publication of the American Federation for Clinical Research\| PubMed ID: 15921033	2005
Vasopressin-dependent myogenic cell differentiation is mediated by both Ca2+/calmodulin-dependent kinase and calcineurin pathways. Molecular biology of the cell\| PubMed ID: 15930130	2005
Youthful prospects for human stem-cell therapy. In another few decades, revised attitudes toward stem cells could lead to disease prevention and life extension. EMBO reports\| PubMed ID: 15995658	2005
Transgenic overexpression of locally acting insulin-like growth factor-1 inhibits ubiquitin-mediated muscle atrophy in chronic left-ventricular dysfunction. Circulation research\| PubMed ID: 16051886	2005
IGF-1, inflammation and stem cells: interactions during muscle regeneration. Trends in immunology\| PubMed ID: 16109502	2005
The future of regenerative therapy in patients with chronic heart failure. Nature clinical practice. Cardiovascular medicine\| PubMed ID: 16501620	2006
The neuroprotective effects of a locally acting IGF-1 isoform. Experimental gerontology\| PubMed ID: 16782294	2007
Growth factor enhancement of cardiac regeneration. Cell transplantation\| PubMed ID: 16826794	2006
Signalling pathways in cardiac regeneration. Novartis Foundation symposium\| PubMed ID: 17019815	2006
Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration. The Journal of clinical investigation\| PubMed ID: 17080195	2006
Local expression of IGF-1 accelerates muscle regeneration by rapidly modulating inflammatory cytokines and chemokines. FASEB journal : official publication of the Federation of American Societies for Experimental Biology\| PubMed ID: 17264161	2007
Identification of novel peptide hormones in the human proteome by hidden Markov model screening. Genome research\| PubMed ID: 17284679	2007
Enhancing repair of the mammalian heart. Circulation research\| PubMed ID: 17525368	2007
Immune response to stem cells and strategies to induce tolerance. Philosophical transactions of the Royal Society of London. Series B, Biological sciences\| PubMed ID: 17584730	2007
ROCK2 and its alternatively spliced isoform ROCK2m positively control the maturation of the myogenic program. Molecular and cellular biology\| PubMed ID: 17606625	2007
Phenostat: visualization and statistical tool for analysis of phenotyping data. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 17674099	2007
The mouse ascending: perspectives for human-disease models. Nature cell biology\| PubMed ID: 17762889	2007
Derive and conquer: sourcing and differentiating stem cells for therapeutic applications. Nature reviews. Drug discovery\| PubMed ID: 18079756	2008
A naturally occurring calcineurin variant inhibits FoxO activity and enhances skeletal muscle regeneration. The Journal of cell biology\| PubMed ID: 18086917	2007
NF-kappaB signaling in skeletal muscle: prospects for intervention in muscle diseases. Journal of molecular medicine (Berlin, Germany)\| PubMed ID: 18246321	2008
Reliability, robustness, and reproducibility in mouse behavioral phenotyping: a cross-laboratory study. Physiological genomics\| PubMed ID: 18505770	2008
Interleukin-10 from transplanted bone marrow mononuclear cells contributes to cardiac protection after myocardial infarction. Circulation research\| PubMed ID: 18566343	2008
Expression of follistatin-related genes is altered in heart failure. Endocrinology\| PubMed ID: 18617621	2008
Analysis of CRE-mediated recombination driven by myosin light chain 1/3 regulatory elements in embryonic and adult skeletal muscle: a tool to study fiber specification. Genesis (New York, N.Y. : 2000)\| PubMed ID: 18693277	2008
Overexpression of mIGF-1 in keratinocytes improves wound healing and accelerates hair follicle formation and cycling in mice. The American journal of pathology\| PubMed ID: 18832567	2008
Skeletal muscle is a primary target of SOD1G93A-mediated toxicity. Cell metabolism\| PubMed ID: 19046573	2008
Multiple congenital malformations of Wolf-Hirschhorn syndrome are recapitulated in Fgfrl1 null mice. Disease models & mechanisms\| PubMed ID: 19383940	2009
Post-publication sharing of data and tools. Nature\| PubMed ID: 19741686	2009
A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 19805133	2009
Distinct roles for cell-autonomous Notch signaling in cardiomyocytes of the embryonic and adult heart. Circulation research\| PubMed ID: 20007915	2010
Insights into the organization of dorsal spinal cord pathways from an evolutionarily conserved raldh2 intronic enhancer. Development (Cambridge, England)\| PubMed ID: 20081195	2010
Models for financial sustainability of biological databases and resources. Database : the journal of biological databases and curation\| PubMed ID: 20157490	2009
A growth stimulus is needed for IGF-1 to induce skeletal muscle hypertrophy in vivo. Journal of cell science\| PubMed ID: 20179101	2010
Analysis of cardiac myocyte biology in transgenic mice: a protocol for preparation of neonatal mouse cardiac myocyte cultures. Methods in molecular biology (Clifton, N.J.)\| PubMed ID: 20204624	2010
Local IGF-1 isoform protects cardiomyocytes from hypertrophic and oxidative stresses via SirT1 activity. Aging\| PubMed ID: 20228935	2010
SirT1 in muscle physiology and disease: lessons from mouse models. Disease models & mechanisms\| PubMed ID: 20354108	2010
Comments on Point:Counterpoint: IGF is/is not the major physiological regulator of muscle mass. IGF-1 is a major regulator of muscle mass during growth but not for adult myofiber hypertrophy... Journal of applied physiology (Bethesda, Md. : 1985)\| PubMed ID: 20527703	2010
Serum and glucocorticoid-inducible kinase 1 (SGK1) is necessary for vascular remodeling during angiogenesis. Developmental dynamics : an official publication of the American Association of Anatomists\| PubMed ID: 20568246	2010
Revealing new mouse epicardial cell markers through transcriptomics. PloS one\| PubMed ID: 20596535	2010
Mouse Resource Browser--a database of mouse databases. Database : the journal of biological databases and curation\| PubMed ID: 20627861	2010
Finding and sharing: new approaches to registries of databases and services for the biomedical sciences. Database : the journal of biological databases and curation\| PubMed ID: 20627863	2010
Regulation of muscle atrophy in aging and disease. Advances in experimental medicine and biology\| PubMed ID: 20886766	2010
Research funding. Sustaining the data and bioresource commons. Science (New York, N.Y.)\| PubMed ID: 21030633	2010
Cre recombinase resources for conditional mouse mutagenesis. Methods (San Diego, Calif.)\| PubMed ID: 21195764	2011
Insulin-like growth factor-1 overexpression in cardiomyocytes diminishes ex vivo heart functional recovery after acute ischemia. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology\| PubMed ID: 21266309	2012
IGF-1Ea induces vessel formation after injury and mediates bone marrow and heart cross-talk through the expression of specific cytokines. Biochemical and biophysical research communications\| PubMed ID: 21621517	2011
Calcineurin splicing variant calcineurin Aβ1 improves cardiac function after myocardial infarction without inducing hypertrophy. Circulation\| PubMed ID: 21632490	2011
MicroRNA-29 in aortic dilation: implications for aneurysm formation. Circulation research\| PubMed ID: 21903938	2011
Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5. PloS one\| PubMed ID: 21931855	2011
mIGF-1/JNK1/SirT1 signaling confers protection against oxidative stress in the heart. Aging cell\| PubMed ID: 22051242	2012
Increased cardiogenesis in P19-GFP teratocarcinoma cells expressing the propeptide IGF-1Ea. Biochemical and biophysical research communications\| PubMed ID: 22100652	2011
Proximal tubule overexpression of a locally acting IGF isoform, Igf-1Ea, increases inflammation after ischemic injury. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society\| PubMed ID: 22197584	2012
In search of a wide-angle perspective. Differentiation; research in biological diversity\| PubMed ID: 22364883	2012
Locally expressed IGF1 propeptide improves mouse heart function in induced dilated cardiomyopathy by blocking myocardial fibrosis and SRF-dependent CTGF induction. Disease models & mechanisms\| PubMed ID: 22563064	2012
An abundant tissue macrophage population in the adult murine heart with a distinct alternatively-activated macrophage profile. PloS one\| PubMed ID: 22590615	2012
Myocardial regenerative properties of macrophage populations and stem cells. Journal of cardiovascular translational research\| PubMed ID: 22684511	2012
CreZOO--the European virtual repository of Cre and other targeted conditional driver strains. Database : the journal of biological databases and curation\| PubMed ID: 22730454	2012
Follistatin-like 3 mediates paracrine fibroblast activation by cardiomyocytes. Journal of cardiovascular translational research\| PubMed ID: 22915069	2012
Beyond knockouts: cre resources for conditional mutagenesis. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 22926223	2012
The mammalian gene function resource: the International Knockout Mouse Consortium. Mammalian genome : official journal of the International Mammalian Genome Society\| PubMed ID: 22968824	2012
E-peptides control bioavailability of IGF-1. PloS one\| PubMed ID: 23251442	2012
Nerve growth factor stimulates cardiac regeneration via cardiomyocyte proliferation in experimental heart failure. PloS one\| PubMed ID: 23300892	2012
Isolation and analysis of single cells from the mouse heart. Journal of immunological methods\| PubMed ID: 23578979	2013
Functional Characterization of a Novel Mutation in NKX2-5 Associated with Congenital Heart Disease and Adult-Onset Cardiomyopathy. Circulation. Cardiovascular genetics\| PubMed ID: 23661673	2013
Macrophages are required for adult salamander limb regeneration. Proceedings of the National Academy of Sciences of the United States of America\| PubMed ID: 23690624	2013
Cardiac fibrosis in mice expressing an inducible myocardial-specific Cre driver. Disease models & mechanisms\| PubMed ID: 23929940	2013
Ablation of SGK1 impairs endothelial cell migration and tube formation leading to decreased neo-angiogenesis following myocardial infarction. PloS one\| PubMed ID: 24265802	2013