Odete A. B. da Cruz e Silva Neuroscience and Signalling Laboratory, Institute of Biomedicine (iBiMED), Department of Medical Sciences University of Aveiro Biography Publications Institution JoVE Articles Odete A. B. da Cruz e Silva has not added a biography. If you are Odete A. B. da Cruz e Silva and would like to personalize this page please email our Author Liaison for assistance. Publications Monitoring Clusterin and Fibrillar Structures in Aging and Dementia Aging Brain. 2023 | Pubmed ID: 37346145 Bioinformatic Analysis of the SPs and NFTs Proteomes Unravel Putative Biomarker Candidates for Alzheimer's Disease Proteomics. Apr, 2023 | Pubmed ID: 37062942 Mitochondria Dysfunction and Impaired Response to Oxidative Stress Promotes Proteostasis Disruption in Aged Human Cells Mitochondrion. Mar, 2023 | Pubmed ID: 36273801 Novel Therapeutic Strategies Targeting Mitochondria As a Gateway in Neurodegeneration Neural Regeneration Research. May, 2023 | Pubmed ID: 36254979 Editorial: Digital Health and Neuroscience: Recent History, Current Trends, and Future Developments Frontiers in Integrative Neuroscience. 2022 | Pubmed ID: 36452883 A Bioinformatics Approach Toward Unravelling the Synaptic Molecular Crosstalk Between Alzheimer's Disease and Diabetes Journal of Alzheimer's Disease : JAD. 2022 | Pubmed ID: 35253743 Novel Exosome Biomarker Candidates for Alzheimer's Disease Unravelled Through Mass Spectrometry Analysis Molecular Neurobiology. May, 2022 | Pubmed ID: 35212939 Revisiting APP Secretases: an Overview on the Holistic Effects of Retinoic Acid Receptor Stimulation in APP Processing Cellular and Molecular Life Sciences : CMLS. Jan, 2022 | Pubmed ID: 35089425 Nuclear Envelope Alterations in Myotonic Dystrophy Type 1 Patient-Derived Fibroblasts International Journal of Molecular Sciences. Jan, 2022 | Pubmed ID: 35008948 The Role of the Integral Type II Transmembrane Protein BRI2 in Health and Disease Cellular and Molecular Life Sciences : CMLS. Nov, 2021 | Pubmed ID: 34480585 Exosomal Aβ-Binding Proteins Identified by "In Silico" Analysis Represent Putative Blood-Derived Biomarker Candidates for Alzheimer´s Disease International Journal of Molecular Sciences. Apr, 2021 | Pubmed ID: 33920336 Fourier-Transform Infrared Spectroscopy As a Discriminatory Tool for Myotonic Dystrophy Type 1 Metabolism: A Pilot Study International Journal of Environmental Research and Public Health. Apr, 2021 | Pubmed ID: 33917301 The Impact of the Early Phase of the COVID-19 Pandemic on Mental-health Services in Europe The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry. Sep, 2021 | Pubmed ID: 33143529 APP Binds to the EGFR Ligands HB-EGF and EGF, Acting Synergistically with EGF to Promote ERK Signaling and Neuritogenesis Molecular Neurobiology. Feb, 2021 | Pubmed ID: 33009641 Diagnostic and Therapeutic Potential of Exosomes in Alzheimer's Disease Journal of Neurochemistry. Jan, 2021 | Pubmed ID: 32618370 IL-8 and MCP-1 Impact on Tau Phosphorylation and Phosphatase Activity Current Alzheimer Research. 2020 | Pubmed ID: 33256579 Nuclear Accumulation of LAP1:TRF2 Complex During DNA Damage Response Uncovers a Novel Role for LAP1 Cells. Jul, 2020 | Pubmed ID: 32751253 In Vitro Cytotoxicity Effects of Zinc Oxide Nanoparticles on Spermatogonia Cells Cells. Apr, 2020 | Pubmed ID: 32357578 Nuclear Envelope Dysfunction and Its Contribution to the Aging Process Aging Cell. May, 2020 | Pubmed ID: 32291910 Potential of FTIR Spectroscopy Applied to Exosomes for Alzheimer's Disease Discrimination: A Pilot Study Journal of Alzheimer's Disease : JAD. 2020 | Pubmed ID: 32039849 Monitoring Plasma Protein Aggregation During Aging Using Conformation-specific Antibodies and FTIR Spectroscopy Clinica Chimica Acta; International Journal of Clinical Chemistry. Mar, 2020 | Pubmed ID: 31790700 Development of a Library of Thiophene-Based Drug-Like Lego Molecules: Evaluation of Their Anion Binding, Transport Properties, and Cytotoxicity Chemistry (Weinheim an Der Bergstrasse, Germany). Jan, 2020 | Pubmed ID: 31696989 NMR Metabolomics to Study the Metabolic Response of Human Osteoblasts to Non-poled and Poled Poly (L-lactic) Acid Magnetic Resonance in Chemistry : MRC. Nov, 2019 | Pubmed ID: 31058384 Capacitive Technologies for Highly Controlled and Personalized Electrical Stimulation by Implantable Biomedical Systems Scientific Reports. Mar, 2019 | Pubmed ID: 30899061 Unravelling Protein Aggregation As an Ageing Related Process or a Neuropathological Response Ageing Research Reviews. May, 2019 | Pubmed ID: 30763619 Nuclear Envelope Dynamics During Mammalian Spermatogenesis: New Insights on Male Fertility Biological Reviews of the Cambridge Philosophical Society. Aug, 2019 | Pubmed ID: 30701647 TorsinA Is Functionally Associated with Spermatogenesis Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. Feb, 2019 | Pubmed ID: 30246678 Exosome Isolation from Distinct Biofluids Using Precipitation and Column-based Approaches PloS One. 2018 | Pubmed ID: 29889903 Identification and Characterization of the BRI2 Interactome in the Brain Scientific Reports. Feb, 2018 | Pubmed ID: 29476059 ABC Transporters Are Key Players in Alzheimer's Disease Journal of Alzheimer's Disease : JAD. 2018 | Pubmed ID: 29171999 Putative Dementia Cases Fluctuate As a Function of Mini-Mental State Examination Cut-Off Points Journal of Alzheimer's Disease : JAD. 2018 | Pubmed ID: 29125486 Toward Neuroproteomics in Biological Psychiatry: A Systems Approach Unravels Okadaic Acid-Induced Alterations in the Neuronal Phosphoproteome Omics : a Journal of Integrative Biology. Sep, 2017 | Pubmed ID: 28934028 Protein Phosphorylation is a Key Mechanism in Alzheimer's Disease Journal of Alzheimer's Disease : JAD. 2017 | Pubmed ID: 28527217 Descriptive Analysis of LAP1 Distribution and That of Associated Proteins Throughout Spermatogenesis Membranes. Apr, 2017 | Pubmed ID: 28387711 Impact of Cytokines and Chemokines on Alzheimer's Disease Neuropathological Hallmarks Current Alzheimer Research. 2017 | Pubmed ID: 28317487 BRI2 Processing and Its Neuritogenic Role Are Modulated by Protein Phosphatase 1 Complexing Journal of Cellular Biochemistry. Sep, 2017 | Pubmed ID: 28176357 Screening Younger Individuals in a Primary Care Setting Flags Putative Dementia Cases and Correlates Gastrointestinal Diseases with Poor Cognitive Performance Dementia and Geriatric Cognitive Disorders. 2017 | Pubmed ID: 27907913 Altered Protein Phosphorylation As a Resource for Potential AD Biomarkers Scientific Reports. Jul, 2016 | Pubmed ID: 27466139 New Cosurface Capacitive Stimulators for the Development of Active Osseointegrative Implantable Devices Scientific Reports. Jul, 2016 | Pubmed ID: 27456818 Lamina Associated Polypeptide 1 (LAP1) Interactome and Its Functional Features Membranes. Jan, 2016 | Pubmed ID: 26784240 Genetic Mutations Strengthen Functional Association of LAP1 with DYT1 Dystonia and Muscular Dystrophy Mutation Research. Reviews in Mutation Research. 2015 | Pubmed ID: 26596547 Amyloid-β Modulates Both AβPP and Tau Phosphorylation Journal of Alzheimer's Disease : JAD. 2015 | Pubmed ID: 25589714 Aβ Influences Cytoskeletal Signaling Cascades with Consequences to Alzheimer's Disease Molecular Neurobiology. Dec, 2015 | Pubmed ID: 25344315 LAP1 is a Crucial Protein for the Maintenance of the Nuclear Envelope Structure and Cell Cycle Progression Molecular and Cellular Biochemistry. Jan, 2015 | Pubmed ID: 25323962 RanBP9 Modulates AICD Localization and Transcriptional Activity Via Direct Interaction with Tip60 Journal of Alzheimer's Disease : JAD. 2014 | Pubmed ID: 25024339 Flavonoids As Therapeutic Compounds Targeting Key Proteins Involved in Alzheimer's Disease ACS Chemical Neuroscience. Feb, 2014 | Pubmed ID: 24328060 An Intriguing Shift Occurs in the Novel Protein Phosphatase 1 Binding Partner, TCTEX1D4: Evidence of Positive Selection in a Pika Model PloS One. 2013 | Pubmed ID: 24130861 TCTEX1D4, a Novel Protein Phosphatase 1 Interactor: Connecting the Phosphatase to the Microtubule Network Biology Open. May, 2013 | Pubmed ID: 23789093 Identification and Characterization of Two Distinct PPP1R2 Isoforms in Human Spermatozoa BMC Cell Biology. Mar, 2013 | Pubmed ID: 23506001 Protein Phosphatase 1γ Isoforms Linked Interactions in the Brain Journal of Molecular Neuroscience : MN. May, 2013 | Pubmed ID: 23080069 Attitudes of Portuguese Health Professionals Toward Adverse Drug Reaction Reporting International Journal of Clinical Pharmacy. Oct, 2012 | Pubmed ID: 22936287 Protein Phosphatase 1α Interacting Proteins in the Human Brain Omics : a Journal of Integrative Biology. 2012 | Pubmed ID: 22321011 Identification and Characterization of a Neuronal Enriched Novel Transcript Encoding the Previously Described P60Fe65 Isoform Journal of Neurochemistry. Dec, 2011 | Pubmed ID: 21824145 Identification of the Human Testis Protein Phosphatase 1 Interactome Biochemical Pharmacology. Nov, 2011 | Pubmed ID: 21382349 Protein Phosphatase 1 Complexes Modulate Sperm Motility and Present Novel Targets for Male Infertility Molecular Human Reproduction. Aug, 2011 | Pubmed ID: 21257602 Wnt Signalling is a Relevant Pathway Contributing to Amyloid Beta- Peptide-mediated Neuropathology in Alzheimer's Disease CNS & Neurological Disorders Drug Targets. Dec, 2010 | Pubmed ID: 20942790 Retrieval of the Alzheimer's Amyloid Precursor Protein from the Endosome to the TGN is S655 Phosphorylation State-dependent and Retromer-mediated Molecular Neurodegeneration. Oct, 2010 | Pubmed ID: 20937087 Enhanced Generation of Alzheimer's Amyloid-beta Following Chronic Exposure to Phorbol Ester Correlates with Differential Effects on Alpha and Epsilon Isozymes of Protein Kinase C Journal of Neurochemistry. Jan, 2009 | Pubmed ID: 19012746 Differential Distribution of Alzheimer's Amyloid Precursor Protein Family Variants in Human Sperm Annals of the New York Academy of Sciences. Jan, 2007 | Pubmed ID: 17405931 Altered Subcellular Distribution of the Alzheimer's Amyloid Precursor Protein Under Stress Conditions Annals of the New York Academy of Sciences. Jan, 2007 | Pubmed ID: 17405930 Alternatively Spliced Protein Variants As Potential Therapeutic Targets for Male Infertility and Contraception Annals of the New York Academy of Sciences. Dec, 2004 | Pubmed ID: 15659832 Amyloid Precursor Protein Interaction Network in Human Testis: Sentinel Proteins for Male Reproduction BMC Bioinformatics. | Pubmed ID: 25591988 Optimized Automated Analysis of Live Neuronal Mitochondria Homeostasis Modulation by Isoform-Specific Retinoic Acid Receptors José J. M. Vitória1, Vinícius de Paula1, Odete A. B. da Cruz e Silva1, Diogo Trigo1 1Neuroscience and Signalling Laboratory, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro JoVE 65452 Neuroscience
Optimized Automated Analysis of Live Neuronal Mitochondria Homeostasis Modulation by Isoform-Specific Retinoic Acid Receptors José J. M. Vitória1, Vinícius de Paula1, Odete A. B. da Cruz e Silva1, Diogo Trigo1 1Neuroscience and Signalling Laboratory, Institute of Biomedicine (iBiMED), Department of Medical Sciences, University of Aveiro JoVE 65452 Neuroscience