Per-Olof Berggren Biography Publications JoVE Articles Per-Olof Berggren has not added a biography. If you are Per-Olof Berggren and would like to personalize this page please email our Author Liaison for assistance. Publications Multiple Inositol Polyphosphate Phosphatase Compartmentalization Separates Inositol Phosphate Metabolism from Inositol Lipid Signaling Biomolecules. May, 2023 | Pubmed ID: 37371464 Longitudinal Monitoring of Pancreatic Islet Damage in Streptozotocin-treated Mice with Optical Coherence Microscopy Biomedical Optics Express. Jan, 2023 | Pubmed ID: 36698658 Uncommon Transplantation Sites: Transplantation of Islets and Islet Organoids in the Anterior Chamber of the Eye of Rodents and Monkeys Methods in Molecular Biology (Clifton, N.J.). 2023 | Pubmed ID: 36507983 Novel Aspects of Intra-islet Communication: Primary Cilia and Filopodia Advances in Biological Regulation. Jan, 2023 | Pubmed ID: 36266190 Treatment of the Metabolic Syndrome by SiRNA Targeting Apolipoprotein CIII BioFactors (Oxford, England). Jan, 2023 | Pubmed ID: 36039858 ATF5 is a Regulator of ER Stress and β-cell Apoptosis in Different Mouse Models of Genetic- and Diet-induced Obesity and Diabetes Mellitus Cellular Signalling. Nov, 2022 | Pubmed ID: 36436799 Drp1 Overexpression Decreases Insulin Content in Pancreatic MIN6 Cells International Journal of Molecular Sciences. Oct, 2022 | Pubmed ID: 36293194 Mitochondrial Impairment and Intracellular Reactive Oxygen Species Alter Primary Cilia Morphology Life Science Alliance. Sep, 2022 | Pubmed ID: 36104081 Inositol Hexakisphosphate Primes Syndapin I/PACSIN 1 Activation in Endocytosis Cellular and Molecular Life Sciences : CMLS. May, 2022 | Pubmed ID: 35534740 Diversity of Respiratory Parameters and Metabolic Adaptation to Low Oxygen Tension in Mesenchymal Stromal Cells Metabolism Open. Mar, 2022 | Pubmed ID: 35528374 Inward and Outward Currents of Native and Cloned K(ATP) Channels (Kir6.2/SUR1) Share Single-channel Kinetic Properties Biochemistry and Biophysics Reports. Jul, 2022 | Pubmed ID: 35434386 Intravital Ca Imaging of Pancreatic β Cell Function After Bariatric Surgery Cell Calcium. Jun, 2022 | Pubmed ID: 35278937 Destabilization of β Cell FIT2 by Saturated Fatty Acids Alter Lipid Droplet Numbers and Contribute to ER Stress and Diabetes Proceedings of the National Academy of Sciences of the United States of America. Mar, 2022 | Pubmed ID: 35254894 Intracameral Microimaging of Maturation of Human IPSC Derivatives into Islet Endocrine Cells Cell Transplantation. 2022 | Pubmed ID: 35156411 Apolipoprotein CIII Reduction Protects White Adipose Tissues Against Obesity-Induced Inflammation and Insulin Resistance in Mice International Journal of Molecular Sciences. Dec, 2021 | Pubmed ID: 35008488 An Integrative Proteomics Method Identifies a Regulator of Translation During Stem Cell Maintenance and Differentiation Nature Communications. Nov, 2021 | Pubmed ID: 34772928 Expression of Truncated Kir6.2 Promotes Insertion of Functionally Inverted ATP-sensitive K Channels Scientific Reports. Nov, 2021 | Pubmed ID: 34728728 Challenges in Stem Cell-derived Islet Replacement Therapy Can Be Overcome Cell Transplantation. 2021 | Pubmed ID: 34565192 Tissue-specific Expression of Insulin Receptor Isoforms in Obesity/type 2 Diabetes Mouse Models Journal of Cellular and Molecular Medicine. May, 2021 | Pubmed ID: 33742502 Lowering Apolipoprotein CIII Protects Against High-fat Diet-induced Metabolic Derangements Science Advances. Mar, 2021 | Pubmed ID: 33712458 Apolipoprotein CIII Is an Important Piece in the Type-1 Diabetes Jigsaw Puzzle International Journal of Molecular Sciences. Jan, 2021 | Pubmed ID: 33477763 XPR1 Mediates the Pancreatic β-Cell Phosphate Flush Diabetes. Jan, 2021 | Pubmed ID: 32826297 Integration of Primary Endocrine Cells and Supportive Cells Using Functionalized Silk Promotes the Formation of Prevascularized Islet-like Clusters ACS Biomaterials Science & Engineering. Feb, 2020 | Pubmed ID: 33464872 Islet Vascularization is Regulated by Primary Endothelial Cilia Via VEGF-A-dependent Signaling ELife. Nov, 2020 | Pubmed ID: 33200981 Studying the Biology of Cytotoxic T Lymphocytes in Vivo with a Fluorescent Granzyme B-mTFP Knock-in Mouse ELife. Jul, 2020 | Pubmed ID: 32696761 Platelet Factor 4 Enhances CD4 T Effector Memory Cell Responses Via Akt-PGC1α-TFAM Signaling-mediated Mitochondrial Biogenesis Journal of Thrombosis and Haemostasis : JTH. Oct, 2020 | Pubmed ID: 32671959 Modelling of Dysregulated Glucagon Secretion in Type 2 Diabetes by Considering Mitochondrial Alterations in Pancreatic α-cells Royal Society Open Science. Jan, 2020 | Pubmed ID: 32218947 Enhanced Expression of β Cell Ca3.1 Channels Impairs Insulin Release and Glucose Homeostasis Proceedings of the National Academy of Sciences of the United States of America. Jan, 2020 | Pubmed ID: 31871187 Intraocular Pressure Monitoring Following Islet Transplantation to the Anterior Chamber of the Eye Nano Letters. Mar, 2020 | Pubmed ID: 31750664 IgGs from Patients with Amyotrophic Lateral Sclerosis and Diabetes Target Caαδ1 Subunits Impairing Islet Cell Function and Survival Proceedings of the National Academy of Sciences of the United States of America. Dec, 2019 | Pubmed ID: 31826954 Noninvasive Intravital High-resolution Imaging of Pancreatic Neuroendocrine Tumours Scientific Reports. Oct, 2019 | Pubmed ID: 31601958 Author Correction: Structural Basis for Delta Cell Paracrine Regulation in Pancreatic Islets Nature Communications. Sep, 2019 | Pubmed ID: 31511521 Structural Basis for Delta Cell Paracrine Regulation in Pancreatic Islets Nature Communications. Aug, 2019 | Pubmed ID: 31420552 Correction To: In Vivo Imaging of Type 1 Diabetes Immunopathology Using Eye-transplanted Islets in NOD Mice Diabetologia. Aug, 2019 | Pubmed ID: 31190158 In Vivo Imaging of Type 1 Diabetes Immunopathology Using Eye-transplanted Islets in NOD Mice Diabetologia. Jul, 2019 | Pubmed ID: 31087105 Assembly of Functionalized Silk Together with Cells to Obtain Proliferative 3D Cultures Integrated in a Network of ECM-like Microfibers Scientific Reports. Apr, 2019 | Pubmed ID: 31000733 Local Release of Rapamycin by Microparticles Delays Islet Rejection Within the Anterior Chamber of the Eye Scientific Reports. Mar, 2019 | Pubmed ID: 30850640 Inositol Pyrophosphates and Akt/PKB: Is the Pancreatic β-cell the Exception to the Rule? Cellular Signalling. Jun, 2019 | Pubmed ID: 30742888 Operational Immune Tolerance Towards Transplanted Allogeneic Pancreatic Islets in Mice and a Non-human Primate Diabetologia. 05, 2019 | Pubmed ID: 30701283 The Eye As a Novel Imaging Site in Diabetes Research Pharmacology & Therapeutics. May, 2019 | Pubmed ID: 30677477 MiR-31 Regulates Energy Metabolism and is Suppressed in T cells from Patients with Sjögren's Syndrome European Journal of Immunology. Feb, 2019 | Pubmed ID: 30307034 Neither Polyphenol-rich Red Wine nor Fenofibrate Affects the Onset of Type-1 Diabetes Mellitus in the BB Rat Laboratory Animal Research. Sep, 2018 | Pubmed ID: 30310409 Blocking Ca Channel β Subunit Reverses Diabetes Cell Reports. Jul, 2018 | Pubmed ID: 30044988 Corrigendum to 'Inositol Hexakisphosphate Kinase 1 is a Metabolic Sensor in Pancreatic β-cells' [Cellular Signalling 46 (2018) 120-128] Cellular Signalling. May, 2018 | Pubmed ID: 29807098 Inositol Hexakisphosphate Kinase 1 is a Metabolic Sensor in Pancreatic β-cells Cellular Signalling. Jun, 2018 | Pubmed ID: 29522819 Paracrine Interactions Within the Pancreatic Islet Determine the Glycemic Set Point Cell Metabolism. Mar, 2018 | Pubmed ID: 29514065 Kynurenic Acid and Gpr35 Regulate Adipose Tissue Energy Homeostasis and Inflammation Cell Metabolism. Feb, 2018 | Pubmed ID: 29414686 Protein Kinase- and Lipase Inhibitors of Inositide Metabolism Deplete IP Indirectly in Pancreatic β-cells: Off-target Effects on Cellular Bioenergetics and Direct Effects on IP6K Activity Cellular Signalling. Jan, 2018 | Pubmed ID: 29042286 Inhibition of C1-Ten PTPase Activity Reduces Insulin Resistance Through IRS-1 and AMPK Pathways Scientific Reports. Dec, 2017 | Pubmed ID: 29259227 Kinetics of Functional Beta Cell Mass Decay in a Diphtheria Toxin Receptor Mouse Model of Diabetes Scientific Reports. Sep, 2017 | Pubmed ID: 28963457 Pancreatic Islet Blood Flow Dynamics in Primates Cell Reports. Aug, 2017 | Pubmed ID: 28793270 A Novel Toolbox to Investigate Tissue Spatial Organization Applied to the Study of the Islets of Langerhans Scientific Reports. Mar, 2017 | Pubmed ID: 28303903 Preservation of Anticancer and Immunosuppressive Properties of Rapamycin Achieved Through Controlled Releasing Particles AAPS PharmSciTech. Oct, 2017 | Pubmed ID: 28251512 Apolipoprotein CIII is a New Player in Diabetes Current Opinion in Lipidology. Feb, 2017 | Pubmed ID: 27875339 Human Beta Cells Produce and Release Serotonin to Inhibit Glucagon Secretion from Alpha Cells Cell Reports. Dec, 2016 | Pubmed ID: 28009296 The Different Faces of the Pancreatic Islet Advances in Experimental Medicine and Biology. 2016 | Pubmed ID: 27586419 Diabetes Prevention Through Antiviral Treatment in Biobreeding Rats Viral Immunology. Oct, 2016 | Pubmed ID: 27505258 The Imidazoline Compound RX871024 Promotes Insulinoma Cell Death Independent of AMP-activated Protein Kinase Inhibition Investigational New Drugs. Aug, 2016 | Pubmed ID: 27221730 Silk Matrices Promote Formation of Insulin-secreting Islet-like Clusters Biomaterials. Jun, 2016 | Pubmed ID: 26986856 TLR3-/4-Priming Differentially Promotes Ca(2+) Signaling and Cytokine Expression and Ca(2+)-Dependently Augments Cytokine Release in HMSCs Scientific Reports. Mar, 2016 | Pubmed ID: 26980664 Liraglutide Compromises Pancreatic β Cell Function in a Humanized Mouse Model Cell Metabolism. Mar, 2016 | Pubmed ID: 26876561 The Anterior Chamber of the Eye is a Transplantation Site That Supports and Enables Visualisation of Beta Cell Development in Mice Diabetologia. May, 2016 | Pubmed ID: 26847769 ARA290 Improves Insulin Release and Glucose Tolerance in Type 2 Diabetic Goto-Kakizaki Rats Molecular Medicine (Cambridge, Mass.). May, 2016 | Pubmed ID: 26736179 PI3K-C2α Knockdown Results in Rerouting of Insulin Signaling and Pancreatic Beta Cell Proliferation Cell Reports. Oct, 2015 | Pubmed ID: 26387957 Spatial and Temporal Coordination of Insulin Granule Exocytosis in Intact Human Pancreatic Islets Diabetologia. Dec, 2015 | Pubmed ID: 26376795 Outer Hair Cell Lateral Wall Structure Constrains the Mobility of Plasma Membrane Proteins PLoS Genetics. Sep, 2015 | Pubmed ID: 26352669 New Insights into the Architecture of the Islet of Langerhans: a Focused Cross-species Assessment Diabetologia. Oct, 2015 | Pubmed ID: 26215305 Glucose Intolerance and Pancreatic β-cell Dysfunction in the Anorectic Anx/anx Mouse American Journal of Physiology. Endocrinology and Metabolism. Aug, 2015 | Pubmed ID: 26126683 The Pancreatic β-cell in Deadly Encounter with Apolipoprotein CIII Cell Cycle (Georgetown, Tex.). 2015 | Pubmed ID: 26102210 Pancreatic Islet Survival and Engraftment Is Promoted by Culture on Functionalized Spider Silk Matrices PloS One. 2015 | Pubmed ID: 26090859 Secretome Protein Signature of Human Gastrointestinal Stromal Tumor Cells Experimental Cell Research. Aug, 2015 | Pubmed ID: 25983130 Apolipoprotein CIII Links Islet Insulin Resistance to β-cell Failure in Diabetes Proceedings of the National Academy of Sciences of the United States of America. May, 2015 | Pubmed ID: 25941406 Regulation of Glucose Homeostasis Using Radiogenetics and Magnetogenetics in Mice Nature Medicine. Jan, 2015 | Pubmed ID: 25569545 β-Cell Ca(2+) Dynamics and Function Are Compromised in Aging Advances in Biological Regulation. Jan, 2015 | Pubmed ID: 25282681 Young Capillary Vessels Rejuvenate Aged Pancreatic Islets Proceedings of the National Academy of Sciences of the United States of America. Dec, 2014 | Pubmed ID: 25404292 Ciliary Dysfunction Impairs Beta-cell Insulin Secretion and Promotes Development of Type 2 Diabetes in Rodents Nature Communications. 2014 | Pubmed ID: 25374274 Defects in β-cell Ca2+ Dynamics in Age-induced Diabetes Diabetes. Dec, 2014 | Pubmed ID: 24985350 Contribution of Endothelial Injury and Inflammation in Early Phase to Vein Graft Failure: the Causal Factors Impact on the Development of Intimal Hyperplasia in Murine Models PloS One. 2014 | Pubmed ID: 24887332 Short and Prolonged Exposure to Hyperglycaemia in Human Fibroblasts and Endothelial Cells: Metabolic and Osmotic Effects The International Journal of Biochemistry & Cell Biology. Aug, 2014 | Pubmed ID: 24814290 Control of Insulin Secretion by Cholinergic Signaling in the Human Pancreatic Islet Diabetes. Aug, 2014 | Pubmed ID: 24658304 AP2-Cre-mediated Inactivation of Estrogen Receptor Alpha Causes Hydrometra PloS One. 2014 | Pubmed ID: 24416430 Reporter Islets in the Eye Reveal the Plasticity of the Endocrine Pancreas Proceedings of the National Academy of Sciences of the United States of America. Dec, 2013 | Pubmed ID: 24248353 Islet Inflammation in Plain Sight Diabetes, Obesity & Metabolism. Sep, 2013 | Pubmed ID: 24003927 Evidence for Ca(2+)-regulated ATP Release in Gastrointestinal Stromal Tumors Experimental Cell Research. May, 2013 | Pubmed ID: 23499741 Estrogen Signalling and the Metabolic Syndrome: Targeting the Hepatic Estrogen Receptor Alpha Action PloS One. 2013 | Pubmed ID: 23451233 New Horizons in Cellular Regulation by Inositol Polyphosphates: Insights from the Pancreatic β-Cell Pharmacological Reviews. 2013 | Pubmed ID: 23429059 C1-Ten is a Protein Tyrosine Phosphatase of IRS-1, Regulating IRS-1 Stability and Muscle Atrophy Molecular and Cellular Biology. Feb, 2013 | Pubmed ID: 23401856 Emodin Regulates Glucose Utilization by Activating AMP-activated Protein Kinase The Journal of Biological Chemistry. Feb, 2013 | Pubmed ID: 23303186 The Pancreatic Islet As a Signaling Hub Advances in Biological Regulation. Jan, 2013 | Pubmed ID: 23073565 Localization of Cholesterol, Amyloid and Glia in Alzheimer's Disease Transgenic Mouse Brain Tissue Using Time-of-flight Secondary Ion Mass Spectrometry (ToF-SIMS) and Immunofluorescence Imaging Acta Neuropathologica. Jan, 2013 | Pubmed ID: 22996963 Noninvasive in Vivo Model Demonstrating the Effects of Autonomic Innervation on Pancreatic Islet Function Proceedings of the National Academy of Sciences of the United States of America. Dec, 2012 | Pubmed ID: 23236142 Glucagon Regulates Its Own Synthesis by Autocrine Signaling Proceedings of the National Academy of Sciences of the United States of America. Dec, 2012 | Pubmed ID: 23213228 The Pancreatic Beta Cell As a Paradigm for Advances in Inositide Research Advances in Biological Regulation. Sep, 2012 | Pubmed ID: 22884029 Inositol Hexakisphosphate Suppresses Excitatory Neurotransmission Via Synaptotagmin-1 C2B Domain in the Hippocampal Neuron Proceedings of the National Academy of Sciences of the United States of America. Jul, 2012 | Pubmed ID: 22778403 Dynamin-mediated Nephrin Phosphorylation Regulates Glucose-stimulated Insulin Release in Pancreatic Beta Cells The Journal of Biological Chemistry. Aug, 2012 | Pubmed ID: 22718751 Real-time Detection of Acetylcholine Release from the Human Endocrine Pancreas Nature Protocols. Jun, 2012 | Pubmed ID: 22555241 Markedly Decreased Blood Perfusion of Pancreatic Islets Transplanted Intraportally into the Liver: Disruption of Islet Integrity Necessary for Islet Revascularization Diabetes. Mar, 2012 | Pubmed ID: 22315321 One-step Purification of Functional Human and Rat Pancreatic Alpha Cells Integrative Biology : Quantitative Biosciences from Nano to Macro. Feb, 2012 | Pubmed ID: 22267247 Transthyretin Binds to Glucose-regulated Proteins and is Subjected to Endocytosis by the Pancreatic β-cell Cellular and Molecular Life Sciences : CMLS. May, 2012 | Pubmed ID: 22183612 Donor Islet Endothelial Cells in Pancreatic Islet Revascularization Diabetes. Oct, 2011 | Pubmed ID: 21873551 High-resolution, Noninvasive Longitudinal Live Imaging of Immune Responses Proceedings of the National Academy of Sciences of the United States of America. Aug, 2011 | Pubmed ID: 21768391 Innervation Patterns of Autonomic Axons in the Human Endocrine Pancreas Cell Metabolism. Jul, 2011 | Pubmed ID: 21723503 Apolipoprotein CIII Reduces Proinflammatory Cytokine-induced Apoptosis in Rat Pancreatic Islets Via the Akt Prosurvival Pathway Endocrinology. Aug, 2011 | Pubmed ID: 21693679 Munc18-1 and Munc18-2 Proteins Modulate Beta-cell Ca2+ Sensitivity and Kinetics of Insulin Exocytosis Differently The Journal of Biological Chemistry. Aug, 2011 | Pubmed ID: 21690086 Alpha Cells Secrete Acetylcholine As a Non-neuronal Paracrine Signal Priming Beta Cell Function in Humans Nature Medicine. Jul, 2011 | Pubmed ID: 21685896 Lowering Apolipoprotein CIII Delays Onset of Type 1 Diabetes Proceedings of the National Academy of Sciences of the United States of America. Jun, 2011 | Pubmed ID: 21670290 Short Telomeres Compromise β-cell Signaling and Survival PloS One. 2011 | Pubmed ID: 21423765 Electrical Short-circuit in β-cells from a Patient with Non-insulinoma Pancreatogenous Hypoglycemic Syndrome (NIPHS): a Case Report Journal of Medical Case Reports. 2010 | Pubmed ID: 20863385 Interleukin-6 Signaling in Liver-parenchymal Cells Suppresses Hepatic Inflammation and Improves Systemic Insulin Action Cell Metabolism. Sep, 2010 | Pubmed ID: 20816090 Diphosphosinositol Polyphosphates and Energy Metabolism: Assay for ATP/ADP Ratio Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20645185 HPLC Separation of Inositol Polyphosphates Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20645179 The Role of Inositol and the Principles of Labelling, Extraction, and Analysis of Inositides in Mammalian Cells Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20645178 Novel Aspects on Pancreatic Beta-cell Signal-transduction Biochemical and Biophysical Research Communications. May, 2010 | Pubmed ID: 20494121 ATP-gated P2X3 Receptors Constitute a Positive Autocrine Signal for Insulin Release in the Human Pancreatic Beta Cell Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20308565 Cholinergic Augmentation of Insulin Release Requires Ankyrin-B Science Signaling. 2010 | Pubmed ID: 20234002 Insulin-feedback Via PI3K-C2alpha Activated PKBalpha/Akt1 is Required for Glucose-stimulated Insulin Secretion FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jun, 2010 | Pubmed ID: 20061534 Lipotoxicity and Decreased Islet Graft Survival Diabetes Care. Mar, 2010 | Pubmed ID: 20009097 Nephrin is Expressed on the Surface of Insulin Vesicles and Facilitates Glucose-stimulated Insulin Release Diabetes. Jan, 2010 | Pubmed ID: 19833886 Pulling Force Generated by Interacting SNAREs Facilitates Membrane Hemifusion Integrative Biology : Quantitative Biosciences from Nano to Macro. Apr, 2009 | Pubmed ID: 20023730 Antiviral Treatments Reduce Severity of Diabetes in Ljungan Virus-infected CD-1 Mice and Delay Onset in Diabetes-prone BB Rats Microbiology and Immunology. Oct, 2009 | Pubmed ID: 19780970 Suppressor of Cytokine Signaling-1 Inhibits Caspase Activation and Protects from Cytokine-induced Beta Cell Death Cellular and Molecular Life Sciences : CMLS. Dec, 2009 | Pubmed ID: 19763396 Inositol Pyrophosphates: Structure, Enzymology and Function Cellular and Molecular Life Sciences : CMLS. Dec, 2009 | Pubmed ID: 19714294 Diphosphoinositol Pentakisphosphate As a Novel Mediator of Insulin Exocytosis Advances in Enzyme Regulation. 2009 | Pubmed ID: 19534030 Beneficial Role of Pancreatic Microenvironment for Angiogenesis in Transplanted Pancreatic Islets Cell Transplantation. 2009 | Pubmed ID: 19476206 Suramin Inhibits the CD40-CD154 Costimulatory Interaction: a Possible Mechanism for Immunosuppressive Effects Biochemical Pharmacology. Apr, 2009 | Pubmed ID: 19283894 An Ancient Duplication of Exon 5 in the Snap25 Gene is Required for Complex Neuronal Development/function PLoS Genetics. Nov, 2008 | Pubmed ID: 19043548 Noninvasive High-resolution in Vivo Imaging of Cell Biology in the Anterior Chamber of the Mouse Eye Nature Protocols. 2008 | Pubmed ID: 18714296 Real-time Monitoring of Apoptosis by Caspase-3-like Protease Induced FRET Reduction Triggered by Amyloid Aggregation Experimental Diabetes Research. 2008 | Pubmed ID: 18566681 Glutamate is a Positive Autocrine Signal for Glucagon Release Cell Metabolism. Jun, 2008 | Pubmed ID: 18522835 Insulin Signaling in the Pancreatic Beta-cell Annual Review of Nutrition. 2008 | Pubmed ID: 18481923 Activin B Receptor ALK7 is a Negative Regulator of Pancreatic Beta-cell Function Proceedings of the National Academy of Sciences of the United States of America. May, 2008 | Pubmed ID: 18480258 Proteins in the Insulin-secreting Cell Line MIN6 Bind the Imidazoline Compound BL11282 FEBS Letters. May, 2008 | Pubmed ID: 18420036 Automated, High-throughput Assays for Evaluation of Human Pancreatic Islet Function Cell Transplantation. 2008 | Pubmed ID: 18351020 Professor Rolf Luft, 1914--2007 Diabetologia. May, 2008 | Pubmed ID: 18327565 Noninvasive in Vivo Imaging of Pancreatic Islet Cell Biology Nature Medicine. May, 2008 | Pubmed ID: 18327249 A Key Role for Phosphorylated Inositol Compounds in Pancreatic Beta-cell Stimulus-secretion Coupling Advances in Enzyme Regulation. 2008 | Pubmed ID: 18194673 Requirement of Inositol Pyrophosphates for Full Exocytotic Capacity in Pancreatic Beta Cells Science (New York, N.Y.). Nov, 2007 | Pubmed ID: 18033884 Distribution of Intraportally Implanted Microspheres and Fluorescent Islets in Mice Cell Transplantation. 2007 | Pubmed ID: 17912953 Glucose Recruits K(ATP) Channels Via Non-insulin-containing Dense-core Granules Cell Metabolism. Sep, 2007 | Pubmed ID: 17767908 Interference with Tissue Factor Prolongs Intrahepatic Islet Allograft Survival in a Nonhuman Primate Marginal Mass Model Transplantation. Aug, 2007 | Pubmed ID: 17700154 3H-serotonin As a Marker of Oscillatory Insulin Secretion in Clonal Beta-cells (INS-1) FEBS Letters. Aug, 2007 | Pubmed ID: 17686476 An Autocrine Insulin Feedback Loop Maintains Pancreatic Beta-cell 3-phosphorylated Inositol Lipids Molecular Endocrinology (Baltimore, Md.). Nov, 2007 | Pubmed ID: 17652185 Tissue-dependent Loss of Phosphofructokinase-M in Mice with Interrupted Activity of the Distal Promoter: Impairment in Insulin Secretion American Journal of Physiology. Endocrinology and Metabolism. Sep, 2007 | Pubmed ID: 17595219 Implantation Site-dependent Dysfunction of Transplanted Pancreatic Islets Diabetes. Jun, 2007 | Pubmed ID: 17400931 R-type Ca(2+)-channel-evoked CICR Regulates Glucose-induced Somatostatin Secretion Nature Cell Biology. Apr, 2007 | Pubmed ID: 17369816 Selective Gene Activation by Spatial Segregation of Insulin Receptor B Signaling FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. May, 2007 | Pubmed ID: 17264162 Downregulation of EGF Receptor Signaling in Pancreatic Islets Causes Diabetes Due to Impaired Postnatal Beta-cell Growth Diabetes. Dec, 2006 | Pubmed ID: 17130473 RX871024 Reduces NO Production but Does Not Protect Against Pancreatic Beta-cell Death Induced by Proinflammatory Cytokines Biochemical and Biophysical Research Communications. Sep, 2006 | Pubmed ID: 16870144 The Role of Voltage-gated Calcium Channels in Pancreatic Beta-cell Physiology and Pathophysiology Endocrine Reviews. Oct, 2006 | Pubmed ID: 16868246 Novel Aspects on Signal-transduction in the Pancreatic Beta-cell Nutrition, Metabolism, and Cardiovascular Diseases : NMCD. Mar, 2006 | Pubmed ID: 16530130 Tomosyn is Expressed in Beta-cells and Negatively Regulates Insulin Exocytosis Diabetes. Mar, 2006 | Pubmed ID: 16505218 The Unique Cytoarchitecture of Human Pancreatic Islets Has Implications for Islet Cell Function Proceedings of the National Academy of Sciences of the United States of America. Feb, 2006 | Pubmed ID: 16461897 Sirt1: a Metabolic Master Switch That Modulates Lifespan Nature Medicine. Jan, 2006 | Pubmed ID: 16397557 Transthyretin Constitutes a Functional Component in Pancreatic Beta-cell Stimulus-secretion Coupling Proceedings of the National Academy of Sciences of the United States of America. Nov, 2005 | Pubmed ID: 16286652 Monomeric G-protein, Rhes, is Not an Imidazoline-regulated Protein in Pancreatic Beta-cells Biochemical and Biophysical Research Communications. Dec, 2005 | Pubmed ID: 16277977 A SIRTain Role in Pancreatic Beta Cell Function Cell Metabolism. Aug, 2005 | Pubmed ID: 16098824 Pancreatic Islet Function in a Transgenic Mouse Expressing Fluorescent Protein The Journal of Endocrinology. Aug, 2005 | Pubmed ID: 16079259 Donor Islet Endothelial Cells Participate in Formation of Functional Vessels Within Pancreatic Islet Grafts Diabetes. Aug, 2005 | Pubmed ID: 16046293 Neuronal Calcium Sensor-1 Potentiates Glucose-dependent Exocytosis in Pancreatic Beta Cells Through Activation of Phosphatidylinositol 4-kinase Beta Proceedings of the National Academy of Sciences of the United States of America. Jul, 2005 | Pubmed ID: 16014415 A Novel Method for the Assessment of Cellular Composition and Beta-cell Viability in Human Islet Preparations American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. Jul, 2005 | Pubmed ID: 15943621 Cyclin-dependent Kinase 5 Activators P35 and P39 Facilitate Formation of Functional Synapses Brain Research. Molecular Brain Research. Aug, 2005 | Pubmed ID: 15908038 Calcium Has a Permissive Role in Interleukin-1beta-induced C-jun N-terminal Kinase Activation in Insulin-secreting Cells Endocrinology. Jul, 2005 | Pubmed ID: 15831571 DARPP-32 and Inhibitor-1 Are Expressed in Pancreatic Beta-cells Biochemical and Biophysical Research Communications. Apr, 2005 | Pubmed ID: 15737638 CaV2.3 Channel and PKClambda: New Players in Insulin Secretion The Journal of Clinical Investigation. Jan, 2005 | Pubmed ID: 15630435 Beta-cell CaV Channel Regulation in Physiology and Pathophysiology American Journal of Physiology. Endocrinology and Metabolism. Jan, 2005 | Pubmed ID: 15585596 Glucagon Stimulates Exocytosis in Mouse and Rat Pancreatic Alpha-cells by Binding to Glucagon Receptors Molecular Endocrinology (Baltimore, Md.). Jan, 2005 | Pubmed ID: 15459251 ATP-sensitive K+ Channel-dependent Regulation of Glucagon Release and Electrical Activity by Glucose in Wild-type and SUR1-/- Mouse Alpha-cells Diabetes. Dec, 2004 | Pubmed ID: 15561909 Removal of Ca2+ Channel Beta3 Subunit Enhances Ca2+ Oscillation Frequency and Insulin Exocytosis Cell. Oct, 2004 | Pubmed ID: 15479643 Mint1, a Munc-18-interacting Protein, is Expressed in Insulin-secreting Beta-cells Biochemical and Biophysical Research Communications. Jul, 2004 | Pubmed ID: 15240107 Apolipoprotein CIII Promotes Ca2+-dependent Beta Cell Death in Type 1 Diabetes Proceedings of the National Academy of Sciences of the United States of America. Jul, 2004 | Pubmed ID: 15210953 Cyclin-dependent Kinase 5 Associated with P39 Promotes Munc18-1 Phosphorylation and Ca(2+)-dependent Exocytosis The Journal of Biological Chemistry. Jul, 2004 | Pubmed ID: 15123626 Growth Hormone Promotes Ca(2+)-induced Ca2+ Release in Insulin-secreting Cells by Ryanodine Receptor Tyrosine Phosphorylation Molecular Endocrinology (Baltimore, Md.). Jul, 2004 | Pubmed ID: 15056730 Isoform-specific Insulin Receptor Signaling Involves Different Plasma Membrane Domains The Journal of Cell Biology. Dec, 2003 | Pubmed ID: 14691140 On-line Monitoring of Apoptosis in Insulin-secreting Cells Diabetes. Dec, 2003 | Pubmed ID: 14633855 Sulfonylureas Rapidly Cross Phospholipid Bilayer Membranes by a Free-diffusion Mechanism Diabetes. Oct, 2003 | Pubmed ID: 14514636 Cytosolic Multiple Inositol Polyphosphate Phosphatase in the Regulation of Cytoplasmic Free Ca2+ Concentration The Journal of Biological Chemistry. Nov, 2003 | Pubmed ID: 12963730 Rapid Association of Protein Kinase C-epsilon with Insulin Granules is Essential for Insulin Exocytosis The Journal of Biological Chemistry. Nov, 2003 | Pubmed ID: 12941947 Dihydroxyacetone-induced Oscillations in Cytoplasmic Free Ca2+ and the ATP/ADP Ratio in Pancreatic Beta-cells at Substimulatory Glucose The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12917415 Suppression of Beta Cell Energy Metabolism and Insulin Release by PGC-1alpha Developmental Cell. Jul, 2003 | Pubmed ID: 12852853 Involvement of Protein Kinase C-epsilon in Inositol Hexakisphosphate-induced Exocytosis in Mouse Pancreatic Beta-cells The Journal of Biological Chemistry. Sep, 2003 | Pubmed ID: 12837755 Phosphatidylinositol 4-kinase Serves As a Metabolic Sensor and Regulates Priming of Secretory Granules in Pancreatic Beta Cells Proceedings of the National Academy of Sciences of the United States of America. Apr, 2003 | Pubmed ID: 12700357 Glibenclamide Inhibits Islet Carnitine Palmitoyltransferase 1 Activity, Leading to PKC-dependent Insulin Exocytosis American Journal of Physiology. Endocrinology and Metabolism. Aug, 2003 | Pubmed ID: 12684219 SUR1 Regulates PKA-independent CAMP-induced Granule Priming in Mouse Pancreatic B-cells The Journal of General Physiology. Mar, 2003 | Pubmed ID: 12601083 Two Generations of Insulinotropic Imidazoline Compounds Diabetes. Dec, 2002 | Pubmed ID: 12475789 Insulin Feedback Action on Pancreatic Beta-cell Function FEBS Letters. Dec, 2002 | Pubmed ID: 12459452 Glucose Metabolites Inhibit Protein Phosphatases and Directly Promote Insulin Exocytosis in Pancreatic Beta-cells Endocrinology. Dec, 2002 | Pubmed ID: 12446586 Phosphorylated Inositol Compounds in Beta -cell Stimulus-response Coupling American Journal of Physiology. Endocrinology and Metabolism. Dec, 2002 | Pubmed ID: 12424101 Increase in Cellular Glutamate Levels Stimulates Exocytosis in Pancreatic Beta-cells FEBS Letters. Nov, 2002 | Pubmed ID: 12417312 Relevance of Dopamine Signals Anchoring Dynamin-2 to the Plasma Membrane During Na+,K+-ATPase Endocytosis The Journal of Biological Chemistry. Nov, 2002 | Pubmed ID: 12205083 Sulfonylurea Receptor Type 1 Knock-out Mice Have Intact Feeding-stimulated Insulin Secretion Despite Marked Impairment in Their Response to Glucose The Journal of Biological Chemistry. Oct, 2002 | Pubmed ID: 12149271 Inositol Hexakisphosphate Promotes Dynamin I- Mediated Endocytosis Proceedings of the National Academy of Sciences of the United States of America. May, 2002 | Pubmed ID: 12011438 Modulation of L-type Ca(2+) Channels by Distinct Domains Within SNAP-25 Diabetes. May, 2002 | Pubmed ID: 11978639 Down-regulated Expression of Exocytotic Proteins in Pancreatic Islets of Diabetic GK Rats Biochemical and Biophysical Research Communications. Mar, 2002 | Pubmed ID: 11866470 Tyrosine 537 Within the Na+,K+-ATPase Alpha-subunit is Essential for AP-2 Binding and Clathrin-dependent Endocytosis The Journal of Biological Chemistry. May, 2002 | Pubmed ID: 11859087 Insulinotropic Activity of the Imidazoline Derivative RX871024 in the Diabetic GK Rat American Journal of Physiology. Endocrinology and Metabolism. Jan, 2002 | Pubmed ID: 11739091 In Vivo Imaging of Liver Spheroids Engrafted in the Anterior Chamber of the Mouse Eye JoVE 66234 Biology استخدام البروتينات النووية الذاتية من الخلايا المزروعة تحت ظروف التاكسج بالانزيم Co-إيمونوبريسيبيتيشن Xiaofeng Zheng1,2, Calvin Qing Wei Ho1, Xiaowei Zheng3, Kian Leong Lee4, Katarina Gradin5, Teresa S. Pereira3, Per-Olof Berggren1,2,3, Yusuf Ali1,2 1Lee Kong Chian School of Medicine, Nanyang Technological University, 2Singapore Eye Research Institute (SERI), Singapore General Hospital, 3The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 4Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 5Department of Cell and Molecular Biology, Karolinska Institutet JoVE 57836 Biology زرع في الغرفة الأمامية للعين لالطولية، غير الغازية Midhat H. Abdulreda1,2, Alejandro Caicedo1,3,4, Per-Olof Berggren1,5 1Diabetes Research Institute, University of Miami Miller School of Medicine, 2Department of Surgery, University of Miami Miller School of Medicine, 3Department of Medicine, University of Miami Miller School of Medicine, 4Department of Physiology & Biophysics, University of Miami Miller School of Medicine, 5The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet JoVE 50466 Medicine
In Vivo Imaging of Liver Spheroids Engrafted in the Anterior Chamber of the Mouse Eye JoVE 66234 Biology
استخدام البروتينات النووية الذاتية من الخلايا المزروعة تحت ظروف التاكسج بالانزيم Co-إيمونوبريسيبيتيشن Xiaofeng Zheng1,2, Calvin Qing Wei Ho1, Xiaowei Zheng3, Kian Leong Lee4, Katarina Gradin5, Teresa S. Pereira3, Per-Olof Berggren1,2,3, Yusuf Ali1,2 1Lee Kong Chian School of Medicine, Nanyang Technological University, 2Singapore Eye Research Institute (SERI), Singapore General Hospital, 3The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet, Karolinska University Hospital, 4Cancer and Stem Cell Biology Program, Duke-NUS Medical School, 5Department of Cell and Molecular Biology, Karolinska Institutet JoVE 57836 Biology
زرع في الغرفة الأمامية للعين لالطولية، غير الغازية Midhat H. Abdulreda1,2, Alejandro Caicedo1,3,4, Per-Olof Berggren1,5 1Diabetes Research Institute, University of Miami Miller School of Medicine, 2Department of Surgery, University of Miami Miller School of Medicine, 3Department of Medicine, University of Miami Miller School of Medicine, 4Department of Physiology & Biophysics, University of Miami Miller School of Medicine, 5The Rolf Luft Research Center for Diabetes and Endocrinology, Karolinska Institutet JoVE 50466 Medicine
