PA

Peter A. Calabresi

Department of Neurology, Johns Hopkins University School of Medicine

Affiliated withJohns Hopkins University School of MedicineUniversity of Vermont

Research Area

Biography

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JoVE Journal Publications

ArticleTotal : 1
Year
Retinal Ganglion Cell Quantification for Evaluating Neurodegeneration in Mouse Models of Multiple Sclerosis​
Publication title
2026

Other Publications

Article
Year
Considerations in the treatment of relapsing-remitting multiple sclerosis.

Neurology| PubMed ID: 11971122

2002
2002
The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS.

The Journal of clinical investigation| PubMed ID: 12782673

2003
2003
2004
Diagnosis and management of multiple sclerosis.

American family physician| PubMed ID: 15571060

2004
2005
2005
2005
2005
The voltage-gated potassium channel Kv1.3 is highly expressed on inflammatory infiltrates in multiple sclerosis brain.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 16043714

2005
2005
Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 16272221

2005
2006
2006
Natalizumab plus interferon beta-1a for relapsing multiple sclerosis.

The New England journal of medicine| PubMed ID: 16510745

2006
Granzyme B mediates neurotoxicity through a G-protein-coupled receptor.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology| PubMed ID: 16636104

2006
2006
2006
2006
2006
Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 17088564

2006
2007
2007
Dendritic cells are abundant in non-lesional gray matter in multiple sclerosis.

Experimental and molecular pathology| PubMed ID: 17662270

2007
2007
2007
2007
2007
2008
2008
Future research directions in multiple sclerosis therapies.

Seminars in neurology| PubMed ID: 18256992

2008
2008
2008
Interleukin-17 in transverse myelitis and multiple sclerosis.

Journal of neuroimmunology| PubMed ID: 18417225

2008
2008
2008
2008
2008
2008
FLT3 inhibitors for the treatment of autoimmune disease.

Expert opinion on investigational drugs| PubMed ID: 18922105

2008
Optical coherence tomography: a window into the mechanisms of multiple sclerosis.

Nature clinical practice. Neurology| PubMed ID: 19043423

2008
Axonal protective effects of the myelin-associated glycoprotein.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 19158290

2009
Natalizumab: bound to rebound?

Neurology| PubMed ID: 19188569

2009
Diffusion tensor magnetic resonance imaging of Wallerian degeneration in rat spinal cord after dorsal root axotomy.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 19279253

2009
2009
2009
2009
2009
2009
2010
2010
2009
2009
2010
2010
Promising treatments of tomorrow for multiple sclerosis.

Annals of Indian Academy of Neurology| PubMed ID: 20182576

2009
2010
2010
Diffusion tensor imaging of the optic tracts in multiple sclerosis: association with retinal thinning and visual disability.

Journal of neuroimaging : official journal of the American Society of Neuroimaging| PubMed ID: 20331501

2011
Activated T-cells inhibit neurogenesis by releasing granzyme B: rescue by Kv1.3 blockers.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 20371822

2010
q-space and conventional diffusion imaging of axon and myelin damage in the rat spinal cord after axotomy.

Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine| PubMed ID: 20432303

2010
2010
2010
2010
Reproducibility of high-resolution optical coherence tomography in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 20530512

2010
FLT-3 expression and function on microglia in multiple sclerosis.

Experimental and molecular pathology| PubMed ID: 20566414

2010
2010
2010
2011
Optical coherence tomography (OCT): imaging the visual pathway as a model for neurodegeneration.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics| PubMed ID: 21274691

2011
Quantitative measures detect sensory and motor impairments in multiple sclerosis.

Journal of the neurological sciences| PubMed ID: 21458828

2011
2011
Emerging injectable therapies for multiple sclerosis.

The Lancet. Neurology| PubMed ID: 24090587

2013
2011
Probing mouse brain microstructure using oscillating gradient diffusion MRI.

Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine| PubMed ID: 21590726

2012
Retinal ganglion cell layer volumetric assessment by spectral-domain optical coherence tomography in multiple sclerosis: application of a high-precision manual estimation technique.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society| PubMed ID: 21654523

2011
In vivo and ex vivo diffusion tensor imaging of cuprizone-induced demyelination in the mouse corpus callosum.

Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine| PubMed ID: 21656567

2012
2011
2011
NMDA receptor signaling in oligodendrocyte progenitors is not required for oligodendrogenesis and myelination.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 21880926

2011
2012
2011
2012
Inflammation in multiple sclerosis--sorting out the gray matter.

The New England journal of medicine| PubMed ID: 22150043

2011
2012
2012
2012
New and emerging disease modifying therapies for multiple sclerosis.

Annals of the New York Academy of Sciences| PubMed ID: 22224673

2012
Visual pathway axonal loss in benign multiple sclerosis: a longitudinal study.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society| PubMed ID: 22269944

2012
2012
2012
2012
2012
2012
2012
2012
2012
2012
2013
Multiparametric MRI correlates of sensorimotor function in the spinal cord in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 22891033

2013
2012
2013
Objective characterization of the relative afferent pupillary defect in MS.

Journal of the neurological sciences| PubMed ID: 23026533

2012
2012
2012
2012
Inhibition of glutamate carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23169655

2012
2013
2013
2013
2013
2013
2013
2013
2013
2013
2013
Anti-interleukin-2 receptor alpha for multiple sclerosis?

Lancet (London, England)| PubMed ID: 23562008

2013
Impaired toll-like receptor 8 signaling in multiple sclerosis.

Journal of neuroinflammation| PubMed ID: 23787171

2013
2013
2013
2013
2013
2013
Induction of IL-17 and nonclassical T-cell activation by HIV-Tat protein.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 23898208

2013
2013
2013
2013
Baseline retinal nerve fiber layer thickness and macular volume quantified by OCT in the North American phase 3 fingolimod trial for relapsing-remitting multiple sclerosis.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society| PubMed ID: 24051419

2013
2013
2013
Voxel-Wise Displacement as Independent Features in Classification of Multiple Sclerosis.

Proceedings of SPIE--the International Society for Optical Engineering| PubMed ID: 24236227

2013
1,25-Dihydroxyvitamin D3 selectively and reversibly impairs T helper-cell CNS localization.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 24324134

2013
2014
DEFORMABLE REGISTRATION OF MACULAR OCT USING A-MODE SCAN SIMILARITY.

Proceedings / IEEE International Symposium on Biomedical Imaging: from nano to macro. IEEE International Symposium on Biomedical Imaging| PubMed ID: 24443687

2013
2014
Author response.

Neurology| PubMed ID: 24571017

2014
Spinal cord normalization in multiple sclerosis.

Journal of neuroimaging : official journal of the American Society of Neuroimaging| PubMed ID: 24593281

2014
2014
2013
2014
2014
2014
Photoreceptor layer thinning in idiopathic Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society| PubMed ID: 24789530

2014
2014
2014
The impact of dynamic balance measures on walking performance in multiple sclerosis.

Neurorehabilitation and neural repair| PubMed ID: 24795162

2015
2014
2014
2014
2014
Reply: photoreceptor layer thinning is not specific for Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society| PubMed ID: 24985343

2014
Analysis of macular OCT images using deformable registration.

Biomedical optics express| PubMed ID: 25071959

2014
2014
Optical coherence tomography should be part of the routine monitoring of patients with multiple sclerosis: yes.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 25160122

2014
2014
2014
2014
2015
Peginterferon beta-1a in multiple sclerosis: 2-year results from ADVANCE.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 25432952

2015
2014
Thalamic lesions in multiple sclerosis by 7T MRI: Clinical implications and relationship to cortical pathology.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 25583851

2015
2015
Automatic segmentation of microcystic macular edema in OCT.

Biomedical optics express| PubMed ID: 25657884

2015
2015
2015
2015
2015
2015
2015
Longitudinal graph-based segmentation of macular OCT using fundus alignment.

Proceedings of SPIE--the International Society for Optical Engineering| PubMed ID: 26023248

2015
Segmentation of microcystic macular edema in Cirrus OCT scans with an exploratory longitudinal study.

Proceedings of SPIE--the International Society for Optical Engineering| PubMed ID: 26023249

2015
2015
Transfer of myelin-reactive th17 cells impairs endogenous remyelination in the central nervous system of cuprizone-fed mice.

The Journal of neuroscience : the official journal of the Society for Neuroscience| PubMed ID: 26041928

2015
Magnetic susceptibility contrast variations in multiple sclerosis lesions.

Journal of magnetic resonance imaging : JMRI| PubMed ID: 26073973

2016
2015
2015
2015
2015
2015
Relation of quantitative visual and neurologic outcomes to fatigue in multiple sclerosis.

Multiple sclerosis and related disorders| PubMed ID: 26195047

2015
2015
Outer retinal changes following acute optic neuritis.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 26209589

2015
Systemic Tolerance Mediated by Melanoma Brain Tumors Is Reversible by Radiotherapy and Vaccination.

Clinical cancer research : an official journal of the American Association for Cancer Research| PubMed ID: 26490306

2015
2016
Metabolomics in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 26754801

2016
Phenytoin in acute optic neuritis: neuroprotective or not?

The Lancet. Neurology| PubMed ID: 26822743

2016
Retinal degeneration in primary-progressive multiple sclerosis: A role for cortical lesions?

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 26993116

2017
2016
Simultaneous Segmentation of Retinal Surfaces and Microcystic Macular Edema in SDOCT Volumes.

Proceedings of SPIE--the International Society for Optical Engineering| PubMed ID: 27199502

2016
Combined registration and motion correction of longitudinal retinal OCT data.

Proceedings of SPIE--the International Society for Optical Engineering| PubMed ID: 27231406

2016
20/40 or Better Visual Acuity After Optic Neuritis: Not as Good as We Once Thought?

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society| PubMed ID: 27472185

2016
An adaptive grid for graph-based segmentation in retinal OCT.

Proceedings of SPIE--the International Society for Optical Engineering| PubMed ID: 27773959

2014
B-Cell Depletion - A Frontier in Monoclonal Antibodies for Multiple Sclerosis.

The New England journal of medicine| PubMed ID: 28001486

2017
2017
CNS-targeted autoimmunity leads to increased influenza mortality in mice.

The Journal of experimental medicine| PubMed ID: 28057805

2017
2017
2018
Optimal Intereye Difference Thresholds in Retinal Nerve Fiber Layer Thickness for Predicting a Unilateral Optic Nerve Lesion in Multiple Sclerosis.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society| PubMed ID: 29384802

2018
Bryostatin-1 alleviates experimental multiple sclerosis.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 29440425

2018
2018
MIMoSA: An Automated Method for Intermodal Segmentation Analysis of Multiple Sclerosis Brain Lesions.

Journal of neuroimaging : official journal of the American Society of Neuroimaging| PubMed ID: 29516669

2018
2018
2018
Joint Intensity Fusion Image Synthesis Applied to Multiple Sclerosis Lesion Segmentation.

Brainlesion : glioma, multiple sclerosis, stroke and traumatic brain injuries. BrainLes (Workshop)| PubMed ID: 29714357

2018
Dice Overlap Measures for Objects of Unknown Number: Application to Lesion Segmentation.

Brainlesion : glioma, multiple sclerosis, stroke and traumatic brain injuries. BrainLes (Workshop)| PubMed ID: 29714358

2018
2018
2019
2018
Alu insertion variants alter mRNA splicing.

Nucleic acids research| PubMed ID: 30418605

2019
2019
2019
PET imaging of microglia by targeting macrophage colony-stimulating factor 1 receptor (CSF1R).

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 30635412

2019
2019
Effect of disease-modifying therapies on subcortical gray matter atrophy in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 30741108

2020
2019
Layer boundary evolution method for macular OCT layer segmentation.

Biomedical optics express| PubMed ID: 30891330

2019
2019
2019
2019
2019
Towards Topological Correct Segmentation of Macular OCT from Cascaded FCNs.

Fetal, Infant and Ophthalmic Medical Image Analysis : International Workshop, FIFI 2017 and 4th International Workshop, OMIA 2017, Held in Conjunction with MICCAI 2017, Quebec City, QC, Canada, September 14, 2017. FIFI (Workshop) (2017 ...| PubMed ID: 31355372

2017
2020
2019
2020
2019
Immune cell modulation of oligodendrocyte lineage cells.

Neuroscience letters| PubMed ID: 31693930

2020
Multi-layer Fast Level Set Segmentation for Macular OCT.

Proceedings. IEEE International Symposium on Biomedical Imaging| PubMed ID: 31853331

2018
Fully Convolutional Boundary Regression for Retina OCT Segmentation.

Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention| PubMed ID: 31853524

2019
2020
Diffusion-time dependence of diffusional kurtosis in the mouse brain.

Magnetic resonance in medicine| PubMed ID: 32022313

2020
Socioeconomic status and race are correlated with affective symptoms in multiple sclerosis.

Multiple sclerosis and related disorders| PubMed ID: 32088654

2020
2020
Association of body mass index with longitudinal rates of retinal atrophy in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 32297826

2020
Imaging Mechanisms of Disease Progression in Multiple Sclerosis: Beyond Brain Atrophy.

Journal of neuroimaging : official journal of the American Society of Neuroimaging| PubMed ID: 32418324

2020
2020
2020
Synaptic and complement markers in extracellular vesicles in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 32669030

2021
2020
2021
2020
2021
Evidence of subclinical quantitative retinal layer abnormalities in AQP4-IgG seropositive NMOSD.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 33307967

2021
Serum ceramide levels are altered in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 33307993

2021
2021
2021
2021
2021
2021
Artificial intelligence extension of the OSCAR-IB criteria.

Annals of clinical and translational neurology| PubMed ID: 34008926

2021
2021
Optic Neuritis-Independent Retinal Atrophy in Neuromyelitis Optica Spectrum Disorder.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society| PubMed ID: 34108402

2022
Therapeutic Potential of a Novel Glucagon-like Peptide-1 Receptor Agonist, NLY01, in Experimental Autoimmune Encephalomyelitis.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics| PubMed ID: 34260042

2021
2021
2021
2021
2021
Measuring treatment response to advance precision medicine for multiple sclerosis.

Annals of clinical and translational neurology| PubMed ID: 34704393

2021
2021
2021
2022
Type of serum collection tube does not impact neurofilament light chain levels.

Multiple sclerosis and related disorders| PubMed ID: 35158190

2022
Breaking the barriers to remyelination in multiple sclerosis.

Current opinion in pharmacology| PubMed ID: 35255453

2022
Response to-.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 35369796

2022
2022
2022
2022
2022
Longitudinal Retinal Changes in MOGAD.

Annals of neurology| PubMed ID: 35703428

2022
2022
Contribution of B cells to cortical damage in multiple sclerosis.

Brain : a journal of neurology| PubMed ID: 35775595

2022
2022
From the prodromal stage of multiple sclerosis to disease prevention.

Nature reviews. Neurology| PubMed ID: 35840705

2022
2022
Visual Pathway Involvement in NMDA Receptor Encephalitis: A Clinical, Optical Coherence Tomography, and 18-Fluorodeoxyglucose PET/CT Approach.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society| PubMed ID: 36000788

2023
Diagnosis and classification of optic neuritis.

The Lancet. Neurology| PubMed ID: 36179757

2022
2023
2022
2022
2022
Association of Vitamin D Polygenic Risk Scores and Disease Outcome in People With Multiple Sclerosis.

Neurology(R) neuroimmunology & neuroinflammation| PubMed ID: 36418179

2023
Associations of sNfL with clinico-radiological measures in a large MS population.

Annals of clinical and translational neurology| PubMed ID: 36427295

2023
2022
2023
2022
2023
2023
2023
Emerging imaging and liquid biomarkers in multiple sclerosis.

European journal of immunology| PubMed ID: 37194443

2023
Longitudinal deep network for consistent OCT layer segmentation.

Biomedical optics express| PubMed ID: 37206119

2023
The Effects of NLY01, a Novel Glucagon-Like Peptide-1 Receptor Agonist, on Cuprizone-Induced Demyelination and Remyelination: Challenges and Future Perspectives.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics| PubMed ID: 37296356

2023
Inhibition of neutral sphingomyelinase 2 impairs HIV-1 envelope formation and substantially delays or eliminates viral rebound.

Proceedings of the National Academy of Sciences of the United States of America| PubMed ID: 37406092

2023
2023
2023
A Phase 1b, Open-Label Study to Evaluate the Safety and Tolerability of the Putative Remyelinating Agent, Liothyronine, in Individuals with MS.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics| PubMed ID: 37460763

2023
Intersite brain MRI volumetric biases persist even in a harmonized multisubject study of multiple sclerosis.

Journal of neuroimaging : official journal of the American Society of Neuroimaging| PubMed ID: 37587544

2023
2023
Do the current MS clinical course descriptors need to change and if so how? A survey of the MS community.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 37691493

2023
2023
2023
2023
2023
2023
2024
Imaging chronic active lesions in multiple sclerosis: a consensus statement.

Brain : a journal of neurology| PubMed ID: 38226694

2024
2024
Recurrent Self Fusion: Iterative Denoising for Consistent Retinal OCT Segmentation.

Ophthalmic medical image analysis : 10th International Workshop, OMIA 2023, held in conjunction with MICCAI 2023, Vancouver, BC, Canada, October 12, 2023, Proceedings. OMIA (Workshop) (10th : 2023 : Vancouver, B.C. ; Online)| PubMed ID: 38318463

2023
Choroid plexus volume differentiates MS from its mimics.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 38481081

2024
2024
2024
Pharmacological modulation of inflammatory oligodendrocyte progenitor cells using three multiple sclerosis disease modifying therapies in vitro.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics| PubMed ID: 38797642

2024
2024
2024
2024
2025
2024
2025
Incorporation of the central vein sign into the McDonald criteria.

Multiple sclerosis and related disorders| PubMed ID: 39622133

2025
2025
2025
2025
2025
2025
2025
Intranasal insulin for improving cognitive function in multiple sclerosis.

Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics| PubMed ID: 40253245

2025
2025
Progress toward Mitigating Disability Progression in Multiple Sclerosis.

The New England journal of medicine| PubMed ID: 40367381

2025
2025
2025
2025
2025
2025
2025
2025
2025
2025
2025
2025
2026
2026
Accelerated metabolomic aging and its association with social determinants of health in multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 41718456

2026
2026
2026
2026
2026
2026
MIF Tautomerase Inhibition Protects Neurons From Immune-Mediated Cell Death.

Neurology(R) neuroimmunology & neuroinflammation| PubMed ID: 42018964

2026
Proteomic Age Acceleration in Multiple Sclerosis Precedes Symptom Onset and Associates with Severity.

medRxiv : the preprint server for health sciences| PubMed ID: 42078367

2026
2026
2026
Association of epiretinal membranes with disability in people with multiple sclerosis.

Multiple sclerosis (Houndmills, Basingstoke, England)| PubMed ID: 42405525

2026
2026
Effect of ocrelizumab on rates of retinal atrophy in relapsing multiple sclerosis.

Multiple sclerosis journal - experimental, translational and clinical| PubMed ID: 42633032

2026
2026
2026