Peter Kuhn Department of Biological Sciences, Dornsife College of Letters, Arts, and Sciences University of Southern California Biography Publications Institution JoVE Articles Peter Kuhn has not added a biography. If you are Peter Kuhn and would like to personalize this page please email our Author Liaison for assistance. Publications Platelet-coated Circulating Tumor Cells Are a Predictive Biomarker in Patients with Metastatic Castrate Resistant Prostate Cancer Molecular Cancer Research : MCR. Aug, 2021 | Pubmed ID: 34462330 Health Economic Evidence for Liquid- and Tissue-based Molecular Tests That Inform Decisions on Prostate Biopsies and Treatment of Localised Prostate Cancer: A Systematic Review European Urology Open Science. May, 2021 | Pubmed ID: 34337517 Inter-eye Genomic Heterogeneity in Bilateral Retinoblastoma Via Aqueous Humor Liquid Biopsy NPJ Precision Oncology. Jul, 2021 | Pubmed ID: 34316014 Model Development of CDK4/6 Predicted Efficacy in Patients With Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced or Metastatic Breast Cancer JCO Clinical Cancer Informatics. Jun, 2021 | Pubmed ID: 34297598 Comprehensive Somatic Copy Number Analysis Using Aqueous Humor Liquid Biopsy for Retinoblastoma Cancers. Jul, 2021 | Pubmed ID: 34283049 Establishing the Clinical Utility of CtDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: The Aqueous Humor Liquid Biopsy Cancers. Mar, 2021 | Pubmed ID: 33805776 Large Extracellular Vesicle Characterization and Association with Circulating Tumor Cells in Metastatic Castrate Resistant Prostate Cancer Cancers. Mar, 2021 | Pubmed ID: 33801459 Treatment Response and Tumor Evolution: Lessons from an Extended Series of Multianalyte Liquid Biopsies in a Metastatic Breast Cancer Patient Cold Spring Harbor Molecular Case Studies. 12, 2020 | Pubmed ID: 33203646 Cell-Free DNA Tumor Fraction in the Aqueous Humor Is Associated With Therapeutic Response in Retinoblastoma Patients Translational Vision Science & Technology. 09, 2020 | Pubmed ID: 33062393 Use of Wearable Activity Tracker in Patients With Cancer Undergoing Chemotherapy: Toward Evaluating Risk of Unplanned Health Care Encounters JCO Clinical Cancer Informatics. 09, 2020 | Pubmed ID: 32970482 Modeling the Onset of Symptoms of COVID-19 Frontiers in Public Health. 2020 | Pubmed ID: 32903584 Multiplexed Probing of Proteolytic Enzymes Using Mass Cytometry-Compatible Activity-Based Probes Journal of the American Chemical Society. 09, 2020 | Pubmed ID: 32870676 Quantified Kinematics to Evaluate Patient Chemotherapy Risks in Clinic JCO Clinical Cancer Informatics. 06, 2020 | Pubmed ID: 32598179 Phase Ib Study of Enzalutamide with or Without Sorafenib in Patients with Advanced Hepatocellular Carcinoma The Oncologist. 12, 2020 | Pubmed ID: 32548867 Liquid Biopsy in Colorectal Carcinoma: Clinical Applications and Challenges Cancers. May, 2020 | Pubmed ID: 32471160 Single-Cell Circulating Tumor Cell Analysis Reveals Genomic Instability As a Distinctive Feature of Aggressive Prostate Cancer Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 08, 2020 | Pubmed ID: 32341031 Minimum Technical Data Elements for Liquid Biopsy Data Submitted to Public Databases Clinical Pharmacology and Therapeutics. 04, 2020 | Pubmed ID: 32017048 Preanalytical Variables for the Genomic Assessment of the Cellular and Acellular Fractions of the Liquid Biopsy in a Cohort of Breast Cancer Patients The Journal of Molecular Diagnostics : JMD. 03, 2020 | Pubmed ID: 31978562 Circulating Tumor Cells: High-Throughput Imaging of CTCs and Bioinformatic Analysis Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer. 2020 | Pubmed ID: 31605225 Single Cell Correlation Analysis of Liquid and Solid Biopsies in Metastatic Colorectal Cancer Oncotarget. Dec, 2019 | Pubmed ID: 31903162 Circulating Tumor Cells As a Response Monitor in Stage IV Non-small Cell Lung Cancer Journal of Translational Medicine. 08, 2019 | Pubmed ID: 31462312 Patient Reported Outcomes Can Improve Performance Status Assessment: a Pilot Study Journal of Patient-reported Outcomes. Jul, 2019 | Pubmed ID: 31313047 Randomized Phase II Trial of Abiraterone Alone or With Dasatinib in Men With Metastatic Castration-resistant Prostate Cancer (mCRPC) Clinical Genitourinary Cancer. 08, 2019 | Pubmed ID: 31227432 Prediction of Bone Metastasis in Inflammatory Breast Cancer Using a Markov Chain Model The Oncologist. 10, 2019 | Pubmed ID: 30952823 Machine Learning Models for Predicting Post-cystectomy Recurrence and Survival in Bladder Cancer Patients PloS One. 2019 | Pubmed ID: 30785915 Single-Cell Analysis of Circulating Tumor Cells Methods in Molecular Biology (Clifton, N.J.). 2019 | Pubmed ID: 30649733 A New Anion Exchange Purification Method for Cu Stable Isotopes in Blood Samples Analytical and Bioanalytical Chemistry. Jan, 2019 | Pubmed ID: 30467768 Histological Validation of 11Carbon-Acetate Positron Emission Tomography/Computerized Tomography in Detecting Lymph Node Metastases in Prostate Cancer The Journal of Urology. 02, 2019 | Pubmed ID: 30218760 Clonal Diversity Revealed by Morphoproteomic and Copy Number Profiles of Single Prostate Cancer Cells at Diagnosis Convergent Science Physical Oncology. Mar, 2018 | Pubmed ID: 32670616 Multiplex Protein Detection on Circulating Tumor Cells from Liquid Biopsies Using Imaging Mass Cytometry Convergent Science Physical Oncology. Mar, 2018 | Pubmed ID: 30906572 Low-dimensional Dynamical Characterization of Human Performance of Cancer Patients Using Motion Data Clinical Biomechanics (Bristol, Avon). 07, 2018 | Pubmed ID: 29803824 Opportunities and Challenges in Implementation of Multiparameter Single Cell Analysis Platforms for Clinical Translation Clinical and Translational Science. 05, 2018 | Pubmed ID: 29498218 Prostate Cancer Disseminated Tumor Cells Are Rarely Detected in the Bone Marrow of Patients with Localized Disease Undergoing Radical Prostatectomy Across Multiple Rare Cell Detection Platforms The Journal of Urology. 06, 2018 | Pubmed ID: 29339080 Development of Metastatic Brain Disease Involves Progression Through Lung Metastases in Mutated Non-small Cell Lung Cancer Convergent Science Physical Oncology. Sep, 2017 | Pubmed ID: 30283700 Circulating Tumor Cells: Fluid Surrogates of Solid Tumors Annual Review of Pathology. Jan, 2017 | Pubmed ID: 28135562 Robotic Salvage Retroperitoneal and Pelvic Lymph Node Dissection for 'node-only' Recurrent Prostate Cancer: Technique and Initial Series BJU International. 09, 2017 | Pubmed ID: 27981731 Paired High-Content Analysis of Prostate Cancer Cells in Bone Marrow and Blood Characterizes Increased Androgen Receptor Expression in Tumor Cell Clusters Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Apr, 2017 | Pubmed ID: 27702818 Vasculogenic Mimicry in Small Cell Lung Cancer Nature Communications. 11, 2016 | Pubmed ID: 27827359 A Multicenter, Open-Label Phase II Clinical Trial of Combined MEK Plus EGFR Inhibition for Chemotherapy-Refractory Advanced Pancreatic Adenocarcinoma Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Jan, 2016 | Pubmed ID: 26251290 The Prothrombotic Activity of Cancer Cells in the Circulation Blood Reviews. Jan, 2016 | Pubmed ID: 26219246 Spatiotemporal Progression of Metastatic Breast Cancer: a Markov Chain Model Highlighting the Role of Early Metastatic Sites NPJ Breast Cancer. 2015 | Pubmed ID: 28721371 Distinctive Structure of the EphA3/Ephrin-A5 Complex Reveals a Dual Mode of Eph Receptor Interaction for Ephrin-A5 PloS One. 2015 | Pubmed ID: 25993310 A Physical Sciences Network Characterization of Circulating Tumor Cell Aggregate Transport American Journal of Physiology. Cell Physiology. May, 2015 | Pubmed ID: 25788574 Fourier-ring Descriptor to Characterize Rare Circulating Cells from Images Generated Using Immunofluorescence Microscopy Computerized Medical Imaging and Graphics : the Official Journal of the Computerized Medical Imaging Society. Mar, 2015 | Pubmed ID: 25456146 The Thrombotic Potential of Circulating Tumor Microemboli: Computational Modeling of Circulating Tumor Cell-induced Coagulation American Journal of Physiology. Cell Physiology. Feb, 2015 | Pubmed ID: 25411332 Entropy, Complexity, and Markov Diagrams for Random Walk Cancer Models Scientific Reports. Dec, 2014 | Pubmed ID: 25523357 Rapid Phenotypic and Genomic Change in Response to Therapeutic Pressure in Prostate Cancer Inferred by High Content Analysis of Single Circulating Tumor Cells PloS One. 2014 | Pubmed ID: 25084170 Adrenal Metastases in Lung Cancer: Clinical Implications of a Mathematical Model Journal of Thoracic Oncology : Official Publication of the International Association for the Study of Lung Cancer. Apr, 2014 | Pubmed ID: 24736064 A Physical Sciences Network Characterization of Non-tumorigenic and Metastatic Cells Scientific Reports. 2013 | Pubmed ID: 23618955 Spreaders and Sponges Define Metastasis in Lung Cancer: A Markov Chain Mathematical Model Cancer Research. Feb, 2013 | Pubmed ID: 23447576 A Stochastic Markov Chain Model to Describe Lung Cancer Growth and Metastasis PloS One. 2012 | Pubmed ID: 22558094 Simultaneous Identification of Clinically Relevant Mutations and Copy Number Alterations in Aqueous Humor of Retinoblastoma Eyes Ophthalmic Genetics. | Pubmed ID: 32799607 Chromosome 6p Amplification in Aqueous Humor Cell-Free DNA Is a Prognostic Biomarker for Retinoblastoma Ocular Survival Molecular Cancer Research : MCR. | Pubmed ID: 32434859 Variability in Retinoblastoma Genome Stability is Driven by Age and Not Heritability Genes, Chromosomes & Cancer. | Pubmed ID: 32390242 Aqueous Humor Is Superior to Blood As a Liquid Biopsy for Retinoblastoma Ophthalmology. | Pubmed ID: 31767439 Genomic CfDNA Analysis of Aqueous Humor in Retinoblastoma Predicts Eye Salvage: The Surrogate Tumor Biopsy for Retinoblastoma Molecular Cancer Research : MCR. | Pubmed ID: 30061186 Potential of Aqueous Humor As a Surrogate Tumor Biopsy for Retinoblastoma JAMA Ophthalmology. | Pubmed ID: 29049475 Aqueous Humor as a Liquid Biopsy for Retinoblastoma: Clear Corneal Paracentesis and Genomic Analysis Mary E. Kim1,2, Liya Xu1,2,3,11, Rishvanth K. Prabakar4, Lishuang Shen5, Chen-Ching Peng1,3, Peter Kuhn3,6,7,8, Xiaowu Gai5,9, James Hicks3,6,10, Jesse L. Berry1,2,6,11 1The Vision Center, Children’s Hospital Los Angeles, 2USC Roski Eye Institute, Keck School of Medicine of the University of Southern California, 3Department of Biological Sciences, Dornsife College of Letters, Arts, and Sciences, University of Southern California, 4Department of Molecular and Computational Biology, University of Southern California, 5Center for Personalized Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles, 6Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 7Department of Aerospace and Mechanical Engineering, Viterbi School of Engineering, University of Southern California, 8Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, 9Department of Pathology and Laboratory Medicine, Keck School of Medicine of USC, 10Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, 11The Saban Research Institute, Children’s Hospital Los Angeles JoVE 62939 Cancer Research
Aqueous Humor as a Liquid Biopsy for Retinoblastoma: Clear Corneal Paracentesis and Genomic Analysis Mary E. Kim1,2, Liya Xu1,2,3,11, Rishvanth K. Prabakar4, Lishuang Shen5, Chen-Ching Peng1,3, Peter Kuhn3,6,7,8, Xiaowu Gai5,9, James Hicks3,6,10, Jesse L. Berry1,2,6,11 1The Vision Center, Children’s Hospital Los Angeles, 2USC Roski Eye Institute, Keck School of Medicine of the University of Southern California, 3Department of Biological Sciences, Dornsife College of Letters, Arts, and Sciences, University of Southern California, 4Department of Molecular and Computational Biology, University of Southern California, 5Center for Personalized Medicine, Department of Pathology and Laboratory Medicine, Children’s Hospital Los Angeles, 6Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 7Department of Aerospace and Mechanical Engineering, Viterbi School of Engineering, University of Southern California, 8Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, 9Department of Pathology and Laboratory Medicine, Keck School of Medicine of USC, 10Department of Biochemistry and Molecular Medicine, Keck School of Medicine, University of Southern California, 11The Saban Research Institute, Children’s Hospital Los Angeles JoVE 62939 Cancer Research