Peter ten Dijke Dept. Cell Chemical Biology Leiden University Medical Center Biography Publications Institution JoVE Articles Peter ten Dijke has not added a biography. If you are Peter ten Dijke and would like to personalize this page please email our Author Liaison for assistance. Publications A Comprehensive Enhancer Screen Identifies TRAM2 As a Key and Novel Mediator of YAP Oncogenesis Genome Biology. Jan, 2021 | Pubmed ID: 33514403 E3 Ubiquitin Ligases: Key Regulators of TGFβ Signaling in Cancer Progression International Journal of Molecular Sciences. Jan, 2021 | Pubmed ID: 33418880 Targeting TGFβ Signal Transduction for Cancer Therapy Signal Transduction and Targeted Therapy. Jan, 2021 | Pubmed ID: 33414388 Therapeutic Targeting of TGF-β in Cancer: Hacking a Master Switch of Immune Suppression Clinical Science (London, England : 1979). Jan, 2021 | Pubmed ID: 33399850 Uncovering the Deubiquitinase Activity Landscape of Breast Cancer Oncoscience. Nov, 2020 | Pubmed ID: 33457450 TGF-β Signaling in Liver Metastasis Clinical and Translational Medicine. Nov, 2020 | Pubmed ID: 33252863 Designed Nanomolar Small-molecule Inhibitors of Ena/VASP EVH1 Interaction Impair Invasion and Extravasation of Breast Cancer Cells Proceedings of the National Academy of Sciences of the United States of America. 11, 2020 | Pubmed ID: 33184177 Current Perspectives on Inhibitory SMAD7 in Health and Disease Critical Reviews in Biochemistry and Molecular Biology. Oct, 2020 | Pubmed ID: 33081543 Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-Terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos Journal of the American Chemical Society. Sep, 2020 | Pubmed ID: 32886496 Mechanotransduction is a Context-dependent Activator of TGF-β Signaling in Mesenchymal Stem Cells Biomaterials. Nov, 2020 | Pubmed ID: 32836056 Cercosporamide Inhibits Bone Morphogenetic Protein Receptor Type I Kinase Activity in Zebrafish Disease Models & Mechanisms. Sep, 2020 | Pubmed ID: 32820031 Reactivation of BMP Signaling by Suboptimal Concentrations of MEK Inhibitor and FK506 Reduces Organ-specific Breast Cancer Metastasis Cancer Letters. Nov, 2020 | Pubmed ID: 32768522 On-Target Anti-TGF-β Therapies Are Not Succeeding in Clinical Cancer Treatments: What Are Remaining Challenges? Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 32733895 Role of Glycosylation in TGF-β Signaling and Epithelial-to-mesenchymal Transition in Cancer Protein & Cell. Jun, 2020 | Pubmed ID: 32583064 Differential - and Glycosphingolipid Glycosylation in Human Pancreatic Adenocarcinoma Cells With Opposite Morphology and Metastatic Behavior Frontiers in Oncology. 2020 | Pubmed ID: 32582529 MnTBAP Reverses Pulmonary Vascular Remodeling and Improves Cardiac Function in Experimentally Induced Pulmonary Arterial Hypertension International Journal of Molecular Sciences. Jun, 2020 | Pubmed ID: 32531895 Bone Morphogenetic Protein Receptors: Structure, Function and Targeting by Selective Small Molecule Kinase Inhibitors Bone. Sep, 2020 | Pubmed ID: 32522605 Secreted BMP Antagonists and Their Role in Cancer and Bone Metastases Bone. Aug, 2020 | Pubmed ID: 32473315 TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering Frontiers in Cell and Developmental Biology. 2020 | Pubmed ID: 32373613 TGFβ and EGF Signaling Orchestrates the AP-1- and P63 Transcriptional Regulation of Breast Cancer Invasiveness Oncogene. May, 2020 | Pubmed ID: 32350443 Development of a 96-well Plate Sample Preparation Method for Integrated N- and O-glycomics Using Porous Graphitized Carbon Liquid Chromatography-mass Spectrometry Molecular Omics. 08, 2020 | Pubmed ID: 32281997 Immunotherapeutic Potential of TGF-β Inhibition and Oncolytic Viruses Trends in Immunology. 05, 2020 | Pubmed ID: 32223932 A Signaling Crosstalk Between BMP9 and HGF/c-Met Regulates Mouse Adult Liver Progenitor Cell Survival Cells. 03, 2020 | Pubmed ID: 32204446 Controlling Smad4 Signaling with a Wip EMBO Reports. 05, 2020 | Pubmed ID: 32189449 Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas Cancer Cell. 03, 2020 | Pubmed ID: 32142668 THG-1 Suppresses SALL4 Degradation to Induce Stemness Genes and Tumorsphere Formation Through Antagonizing NRBP1 in Squamous Cell Carcinoma Cells Biochemical and Biophysical Research Communications. 03, 2020 | Pubmed ID: 31864704 TGFβ-induced Metabolic Reprogramming During Epithelial-to-mesenchymal Transition in Cancer Cellular and Molecular Life Sciences : CMLS. Jun, 2020 | Pubmed ID: 31822964 Tacrolimus-Induced BMP/SMAD Signaling Associates With Metabolic Stress-Activated FOXO1 to Trigger β-Cell Failure Diabetes. 02, 2020 | Pubmed ID: 31732500 VprBP Mitigates TGF-β and Activin Signaling by Promoting Smurf1-mediated Type I Receptor Degradation Journal of Molecular Cell Biology. 02, 2020 | Pubmed ID: 31291647 Development of Macrocycle Kinase Inhibitors for ALK2 Using Fibrodysplasia Ossificans Progressiva-Derived Endothelial Cells JBMR Plus. Nov, 2019 | Pubmed ID: 31768489 JNK-Dependent CJun Phosphorylation Mitigates TGFβ- and EGF-Induced Pre-Malignant Breast Cancer Cell Invasion by Suppressing AP-1-Mediated Transcriptional Responses Cells. 11, 2019 | Pubmed ID: 31766464 A Perspective on the Development of TGF-β Inhibitors for Cancer Treatment Biomolecules. 11, 2019 | Pubmed ID: 31744193 Author Correction: C-Met Activation Leads to the Establishment of a TGFβ-receptor Regulatory Network in Bladder Cancer Progression Nature Communications. Nov, 2019 | Pubmed ID: 31704935 GREM1 is Associated with Metastasis and Predicts Poor Prognosis in ER-negative Breast Cancer Patients Cell Communication and Signaling : CCS. 11, 2019 | Pubmed ID: 31694641 C-Met Activation Leads to the Establishment of a TGFβ-receptor Regulatory Network in Bladder Cancer Progression Nature Communications. 09, 2019 | Pubmed ID: 31554791 Cancer-associated Fibroblast-derived Gremlin 1 Promotes Breast Cancer Progression Breast Cancer Research : BCR. 09, 2019 | Pubmed ID: 31533776 In Vivo Imaging of TGFβ Signalling Components Using Positron Emission Tomography Drug Discovery Today. 12, 2019 | Pubmed ID: 31494189 Role of Soluble Endoglin in BMP9 Signaling Proceedings of the National Academy of Sciences of the United States of America. 09, 2019 | Pubmed ID: 31431534 Prevention of Progression of Pulmonary Hypertension by the Nur77 Agonist 6-mercaptopurine: Role of BMP Signalling The European Respiratory Journal. 09, 2019 | Pubmed ID: 31273046 Autophagy Contributes to BMP Type 2 Receptor Degradation And development of Pulmonary Arterial Hypertension The Journal of Pathology. 11, 2019 | Pubmed ID: 31257577 Generation of Non-standard Macrocyclic Peptides Specifically Binding TSC-22 Homologous Gene-1 Biochemical and Biophysical Research Communications. 08, 2019 | Pubmed ID: 31227214 TGF-β-Mediated Epithelial-Mesenchymal Transition and Cancer Metastasis International Journal of Molecular Sciences. Jun, 2019 | Pubmed ID: 31195692 Epigenetic Reprogramming of TGF-β Signaling in Breast Cancer Cancers. May, 2019 | Pubmed ID: 31137748 Combined Inhibition of TGF-β Signaling and the PD-L1 Immune Checkpoint Is Differentially Effective in Tumor Models Cells. 04, 2019 | Pubmed ID: 30959852 TGF-β Family Signaling Pathways in Cellular Dormancy Trends in Cancer. 01, 2019 | Pubmed ID: 30616757 Inflammation Induces Endothelial-to-mesenchymal Transition and Promotes Vascular Calcification Through Downregulation of BMPR2 The Journal of Pathology. 03, 2019 | Pubmed ID: 30430573 Bone Morphogenetic Protein Receptor Signal Transduction in Human Disease The Journal of Pathology. 01, 2019 | Pubmed ID: 30246251 The Therapeutic Potential of Targeting the Endothelial-to-mesenchymal Transition Angiogenesis. 02, 2019 | Pubmed ID: 30076548 Epithelial-mesenchymal-transition-inducing Transcription Factors: New Targets for Tackling Chemoresistance in Cancer? Oncogene. 11, 2018 | Pubmed ID: 30002444 Endoglin Expression on Cancer-Associated Fibroblasts Regulates Invasion and Stimulates Colorectal Cancer Metastasis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. 12, 2018 | Pubmed ID: 29945992 Bone Morphogenetic Protein 9 As a Key Regulator of Liver Progenitor Cells in DDC-induced Cholestatic Liver Injury Liver International : Official Journal of the International Association for the Study of the Liver. 09, 2018 | Pubmed ID: 29751359 TGF-β Family Co-receptor Function and Signaling Acta Biochimica Et Biophysica Sinica. Jan, 2018 | Pubmed ID: 29293886 JUNB Governs a Feed-forward Network of TGFβ Signaling That Aggravates Breast Cancer Invasion Nucleic Acids Research. 02, 2018 | Pubmed ID: 29186616 Endothelial-to-mesenchymal Transition in Cardiovascular Diseases: Developmental Signaling Pathways Gone Awry Developmental Dynamics : an Official Publication of the American Association of Anatomists. 03, 2018 | Pubmed ID: 28891150 Breast Cancer Metastasis Suppressor OTUD1 Deubiquitinates SMAD7 Nature Communications. 12, 2017 | Pubmed ID: 29235476 TGF-β-Induced Endothelial-Mesenchymal Transition in Fibrotic Diseases International Journal of Molecular Sciences. Oct, 2017 | Pubmed ID: 29039786 Disparate Phospho-Smad2 Levels in Advanced Type 2 Diabetes Patients with Diabetic Nephropathy and Early Experimental Db/db Mouse Model Renal Failure. Nov, 2017 | Pubmed ID: 28805484 Bone Morphogenetic Protein 9 Protects Against Neonatal Hyperoxia-Induced Impairment of Alveolarization and Pulmonary Inflammation Frontiers in Physiology. 2017 | Pubmed ID: 28751863 Targeting TGF-β Signaling in Cancer Trends in Cancer. 01, 2017 | Pubmed ID: 28718426 SUMO-triggered Ubiquitination of NR4A1 Controls Macrophage Cell Death Cell Death and Differentiation. 09, 2017 | Pubmed ID: 28622293 TGFβ1-induced SMAD2/3 and SMAD1/5 Phosphorylation Are Both ALK5-kinase-dependent in Primary Chondrocytes and Mediated by TAK1 Kinase Activity Arthritis Research & Therapy. May, 2017 | Pubmed ID: 28569204 Erratum To: BMP Type II Receptor As a Therapeutic Target in Pulmonary Arterial Hypertension Cellular and Molecular Life Sciences : CMLS. 08, 2017 | Pubmed ID: 28536788 USP4 Inhibits SMAD4 Monoubiquitination and Promotes Activin and BMP Signaling The EMBO Journal. 06, 2017 | Pubmed ID: 28468752 BMP Type II Receptor As a Therapeutic Target in Pulmonary Arterial Hypertension Cellular and Molecular Life Sciences : CMLS. 08, 2017 | Pubmed ID: 28447104 FAF1 Phosphorylation by AKT Accumulates TGF-β Type II Receptor and Drives Breast Cancer Metastasis Nature Communications. 04, 2017 | Pubmed ID: 28443643 Bone Morphogenetic Proteins in Vascular Homeostasis and Disease Cold Spring Harbor Perspectives in Biology. Mar, 2017 | Pubmed ID: 28348038 TGF-β Signaling in Control of Cardiovascular Function Cold Spring Harbor Perspectives in Biology. Mar, 2017 | Pubmed ID: 28348036 BMP-9 Interferes with Liver Regeneration and Promotes Liver Fibrosis Gut. May, 2017 | Pubmed ID: 28336518 Fluid Shear Stress-induced TGF-β/ALK5 Signaling in Renal Epithelial Cells is Modulated by MEK1/2 Cellular and Molecular Life Sciences : CMLS. Feb, 2017 | Pubmed ID: 28168444 TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation The Journal of Biological Chemistry. Mar, 2017 | Pubmed ID: 28115518 Smad2 Phosphorylation in Diabetic Kidney Tubule Epithelial Cells Is Associated with Modulation of Several Transforming Growth Factor-β Family Members Nephron. 2017 | Pubmed ID: 28064277 New Function of the Myostatin/activin Type I Receptor (ALK4) As a Mediator of Muscle Atrophy and Muscle Regeneration FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Jan, 2017 | Pubmed ID: 27733450 Fish Tales: The Use of Zebrafish Xenograft Human Cancer Cell Models Histology and Histopathology. Dec, 2016 | Pubmed ID: 27933602 Immunoregulation by Members of the TGFβ Superfamily Nature Reviews. Immunology. 11, 2016 | Pubmed ID: 27885276 Towards a Cure for Fibrodysplasia Ossificans Progressiva Annals of Translational Medicine. Oct, 2016 | Pubmed ID: 27867996 Mutational Activation of BRAF Confers Sensitivity to Transforming Growth Factor Beta Inhibitors in Human Cancer Cells Oncotarget. Dec, 2016 | Pubmed ID: 27835901 Targeting Tumour Vasculature by Inhibiting Activin Receptor-like Kinase (ALK)1 Function Biochemical Society Transactions. Aug, 2016 | Pubmed ID: 27528762 A Current Perspective on Applications of Macrocyclic-peptide-based High-affinity Ligands Biopolymers. Nov, 2016 | Pubmed ID: 27352774 C-Myb Enhances Breast Cancer Invasion and Metastasis Through the Wnt/β-Catenin/Axin2 Pathway Cancer Research. Jun, 2016 | Pubmed ID: 27197202 Delta-Like Ligand 4 Modulates Liver Damage by Down-Regulating Chemokine Expression The American Journal of Pathology. Jul, 2016 | Pubmed ID: 27171900 Regulation of the TGF-β Pathway by Deubiquitinases in Cancer The International Journal of Biochemistry & Cell Biology. Jul, 2016 | Pubmed ID: 27155333 Smad6 Determines BMP-regulated Invasive Behaviour of Breast Cancer Cells in a Zebrafish Xenograft Model Scientific Reports. Apr, 2016 | Pubmed ID: 27113436 Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease Journal of the American Society of Nephrology : JASN. Dec, 2016 | Pubmed ID: 27020852 Emerging Regulators of BMP Bioavailability Bone. Dec, 2016 | Pubmed ID: 26825814 The Rationale for Targeting TGF-β in Chronic Liver Diseases European Journal of Clinical Investigation. Apr, 2016 | Pubmed ID: 26823073 TGF-β Signalling and Liver Disease The FEBS Journal. Jun, 2016 | Pubmed ID: 26807763 Interrogating TGF-β Function and Regulation in Endothelial Cells Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26520125 Determining TGF-β Receptor Levels in the Cell Membrane Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26520116 In Brief: Endothelial-to-mesenchymal Transition The Journal of Pathology. Feb, 2016 | Pubmed ID: 26446982 Regulatory RNAs Controlling Vascular (dys)function by Affecting TGF-ß Family Signalling EXCLI Journal. 2015 | Pubmed ID: 26862319 Signal Transduction: Gain of Activin Turns Muscle into Bone Current Biology : CB. Dec, 2015 | Pubmed ID: 26654374 Induced Pluripotent Stem Cells to Model Human Fibrodysplasia Ossificans Progressiva Stem Cell Reports. Dec, 2015 | Pubmed ID: 26626181 Targeting BMP Signalling in Cardiovascular Disease and Anaemia Nature Reviews. Cardiology. Oct, 2015 | Pubmed ID: 26461965 Bone Morphogenetic Protein 6 and Oxidized Low-density Lipoprotein Synergistically Recruit Osteogenic Differentiation in Endothelial Cells Cardiovascular Research. Nov, 2015 | Pubmed ID: 26410368 Heterozygous Disruption of Activin Receptor-like Kinase 1 is Associated with Increased Arterial Pressure in Mice Disease Models & Mechanisms. Nov, 2015 | Pubmed ID: 26398936 Activin Receptor-like Kinase 1 Ligand Trap Reduces Microvascular Density and Improves Chemotherapy Efficiency to Various Solid Tumors Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. Sep, 2015 | Pubmed ID: 26373572 Bone Morphogenetic Protein Signaling in Bone Homeostasis Bone. Nov, 2015 | Pubmed ID: 26051467 A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins Journal of Virology. Aug, 2015 | Pubmed ID: 26041291 Genetic Depletion and Pharmacological Targeting of αv Integrin in Breast Cancer Cells Impairs Metastasis in Zebrafish and Mouse Xenograft Models Breast Cancer Research : BCR. Feb, 2015 | Pubmed ID: 25849225 Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2 Gastroenterology. Jun, 2015 | Pubmed ID: 25736321 14-3-3ζ Turns TGF-β to the Dark Side Cancer Cell. Feb, 2015 | Pubmed ID: 25670073 SLUG is Expressed in Endothelial Cells Lacking Primary Cilia to Promote Cellular Calcification Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2015 | Pubmed ID: 25633317 Clinical Utility Gene Card For: Fibrodysplasia Ossificans Progressiva European Journal of Human Genetics : EJHG. Oct, 2015 | Pubmed ID: 25604857 Inhibition of TGFβ Type I Receptor Activity Facilitates Liver Regeneration Upon Acute CCl4 Intoxication in Mice Archives of Toxicology. Jan, 2015 | Pubmed ID: 25566828 Ter94/VCP is a Novel Component Involved in BMP Signaling PloS One. 2014 | Pubmed ID: 25469707 Wild-type P53 Inhibits Pro-invasive Properties of TGF-β3 in Breast Cancer, in Part Through Regulation of EPHB2, a New TGF-β Target Gene Breast Cancer Research and Treatment. Nov, 2014 | Pubmed ID: 25257729 Assessment of Functional Competence of Endothelial Cells from Human Pluripotent Stem Cells in Zebrafish Embryos Methods in Molecular Biology (Clifton, N.J.). 2014 | Pubmed ID: 25173378 Time-resolved Dissection of Early Phosphoproteome and Ensuing Proteome Changes in Response to TGF-β Science Signaling. Jul, 2014 | Pubmed ID: 25056879 Generation, Expansion and Functional Analysis of Endothelial Cells and Pericytes Derived from Human Pluripotent Stem Cells Nature Protocols. 2014 | Pubmed ID: 24874816 Loss of SMAD4 Alters BMP Signaling to Promote Colorectal Cancer Cell Metastasis Via Activation of Rho and ROCK Gastroenterology. Jul, 2014 | Pubmed ID: 24704720 Targeting TGF-β Signaling by Antisense Oligonucleotide-mediated Knockdown of TGF-β Type I Receptor Molecular Therapy. Nucleic Acids. Apr, 2014 | Pubmed ID: 24691207 Nuclear Receptor NR4A1 Promotes Breast Cancer Invasion and Metastasis by Activating TGF-β Signalling Nature Communications. 2014 | Pubmed ID: 24584437 ENDOGLIN is Dispensable for Vasculogenesis, but Required for Vascular Endothelial Growth Factor-induced Angiogenesis PloS One. 2014 | Pubmed ID: 24489709 Novel Ex Vivo Culture Method for the Study of Dupuytren's Disease: Effects of TGFβ Type 1 Receptor Modulation by Antisense Oligonucleotides Molecular Therapy. Nucleic Acids. 2014 | Pubmed ID: 24448195 Functionality of Endothelial Cells and Pericytes from Human Pluripotent Stem Cells Demonstrated in Cultured Vascular Plexus and Zebrafish Xenografts Arteriosclerosis, Thrombosis, and Vascular Biology. Jan, 2014 | Pubmed ID: 24158517 Mutational Analysis of Sclerostin Shows Importance of the Flexible Loop and the Cystine-knot for Wnt-signaling Inhibition PloS One. 2013 | Pubmed ID: 24312339 Signaling Interplay Between Transforming Growth Factor-β Receptor and PI3K/AKT Pathways in Cancer Trends in Biochemical Sciences. Dec, 2013 | Pubmed ID: 24239264 Transforming Growth Factor-β Signalling Controls Human Breast Cancer Metastasis in a Zebrafish Xenograft Model Breast Cancer Research : BCR. Nov, 2013 | Pubmed ID: 24196484 Activin Receptor-like Kinase 1 As a Target for Anti-angiogenesis Therapy Expert Opinion on Investigational Drugs. Nov, 2013 | Pubmed ID: 24053899 Transforming Growth Factor-β (TGF-β)-mediated Connective Tissue Growth Factor (CTGF) Expression in Hepatic Stellate Cells Requires Stat3 Signaling Activation The Journal of Biological Chemistry. Oct, 2013 | Pubmed ID: 24005672 TRAF4 Promotes TGF-β Receptor Signaling and Drives Breast Cancer Metastasis Molecular Cell. Sep, 2013 | Pubmed ID: 23973329 FK506 Activates BMPR2, Rescues Endothelial Dysfunction, and Reverses Pulmonary Hypertension The Journal of Clinical Investigation. Aug, 2013 | Pubmed ID: 23867624 Antisense-oligonucleotide Mediated Exon Skipping in Activin-receptor-like Kinase 2: Inhibiting the Receptor That is Overactive in Fibrodysplasia Ossificans Progressiva PloS One. 2013 | Pubmed ID: 23861958 Three-dimensional Co-cultures of Human Endothelial Cells and Embryonic Stem Cell-derived Pericytes Inside a Microfluidic Device Lab on a Chip. Sep, 2013 | Pubmed ID: 23702711 Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-mediated Antagonism of Wnt/LRP6 Signaling PloS One. 2013 | Pubmed ID: 23638027 Snail and Slug, Key Regulators of TGF-β-induced EMT, Are Sufficient for the Induction of Single-cell Invasion Biochemical and Biophysical Research Communications. May, 2013 | Pubmed ID: 23618854 Preventive and Therapeutic Effects of Smad7 on Radiation-induced Oral Mucositis Nature Medicine. Apr, 2013 | Pubmed ID: 23475202 Fine-tuning BMP7 Signalling in Adipogenesis by UBE2O/E2-230K-mediated Monoubiquitination of SMAD6 The EMBO Journal. Apr, 2013 | Pubmed ID: 23455153 Deficiency for Endoglin in Tumor Vasculature Weakens the Endothelial Barrier to Metastatic Dissemination The Journal of Experimental Medicine. Mar, 2013 | Pubmed ID: 23401487 UBE2O Negatively Regulates TRAF6-mediated NF-κB Activation by Inhibiting TRAF6 Polyubiquitination Cell Research. Mar, 2013 | Pubmed ID: 23381138 Endoglin for Tumor Imaging and Targeted Cancer Therapy Expert Opinion on Therapeutic Targets. Apr, 2013 | Pubmed ID: 23327677 Overactive Bone Morphogenetic Protein Signaling in Heterotopic Ossification and Duchenne Muscular Dystrophy Cellular and Molecular Life Sciences : CMLS. Feb, 2013 | Pubmed ID: 22752156 Soluble Fms-like Tyrosine Kinase 1 and Soluble Endoglin Are Elevated Circulating Anti-angiogenic Factors in Pre-eclampsia Pregnancy Hypertension. Oct, 2012 | Pubmed ID: 26105603 MicroRNA-155 Functions As a Negative Regulator of RhoA Signaling in TGF-β-induced Endothelial to Mesenchymal Transition MicroRNA (Shariqah, United Arab Emirates). 2012 | Pubmed ID: 25048084 慢性肝脏疾病的动物模型。 American Journal of Physiology. Gastrointestinal and Liver Physiology. Dec, 2012 | Pubmed ID: 23275613 MED12 Controls the Response to Multiple Cancer Drugs Through Regulation of TGF-β Receptor Signaling Cell. Nov, 2012 | Pubmed ID: 23178117 The Activities of Smad and Gli Mediated Signalling Pathways in High-grade Conventional Osteosarcoma European Journal of Cancer (Oxford, England : 1990). Dec, 2012 | Pubmed ID: 22868198 Fas-associated Factor 1 is a Scaffold Protein That Promotes β-transducin Repeat-containing Protein (β-TrCP)-mediated β-catenin Ubiquitination and Degradation The Journal of Biological Chemistry. Aug, 2012 | Pubmed ID: 22730322 TGF-β Signalling and Its Role in Cancer Progression and Metastasis Cancer Metastasis Reviews. Dec, 2012 | Pubmed ID: 22714591 BMP Signaling in Vascular Diseases FEBS Letters. Jul, 2012 | Pubmed ID: 22710160 USP4 is Regulated by AKT Phosphorylation and Directly Deubiquitylates TGF-β Type I Receptor Nature Cell Biology. Jun, 2012 | Pubmed ID: 22706160 TGFβ Signaling in Liver Regeneration Current Pharmaceutical Design. 2012 | Pubmed ID: 22630085 Deregulated Bone Morphogenetic Protein Receptor Signaling Underlies Fibrodysplasia Ossificans Progressiva Current Pharmaceutical Design. 2012 | Pubmed ID: 22630080 Role of Endoglin in Fibrosis and Scleroderma International Review of Cell and Molecular Biology. 2012 | Pubmed ID: 22608563 LRP8 Mediates Wnt/β-catenin Signaling and Controls Osteoblast Differentiation Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Oct, 2012 | Pubmed ID: 22589174 RNF12 Controls Embryonic Stem Cell Fate and Morphogenesis in Zebrafish Embryos by Targeting Smad7 for Degradation Molecular Cell. Jun, 2012 | Pubmed ID: 22560923 Anti-human Activin Receptor-like Kinase 1 (ALK1) Antibody Attenuates Bone Morphogenetic Protein 9 (BMP9)-induced ALK1 Signaling and Interferes with Endothelial Cell Sprouting The Journal of Biological Chemistry. May, 2012 | Pubmed ID: 22493445 Shear Induced Collateral Artery Growth Modulated by Endoglin but Not by ALK1 Journal of Cellular and Molecular Medicine. Oct, 2012 | Pubmed ID: 22436015 Vanilloid Receptor-1 Regulates Neurogenic Inflammation in Colon and Protects Mice from Colon Cancer Cancer Research. Apr, 2012 | Pubmed ID: 22396497 TGF-β Signaling in Endothelial-to-mesenchymal Transition: the Role of Shear Stress and Primary Cilia Science Signaling. Feb, 2012 | Pubmed ID: 22355187 泛素蛋白修饰在 TGFβ 信号转导中的关键作用。 Upsala Journal of Medical Sciences. Feb, 2012 | Pubmed ID: 22335355 Wnt/β-连环素信号诱导 Id3 表达式更改 C2C12 成肌细胞增殖和分化。 Biochemical and Biophysical Research Communications. Feb, 2012 | Pubmed ID: 22326917 信号乳腺发育和癌症中的节点的键: Smad 信号一体化的上皮细胞可塑性。 Breast Cancer Research : BCR. Feb, 2012 | Pubmed ID: 22315972 共价键二聚化行为人重组骨形态发生蛋白-15 Variant 类型标识骨形态发生蛋白受体键入 1B 作为关键细胞对卵巢颗粒细胞的表面受体。 Endocrinology. Jan, 2012 | Pubmed ID: 22294741 非同义 SMAD6 基因变异会发展成先天性心血管畸形。 Human Mutation. Jan, 2012 | Pubmed ID: 22275001 特定的泛素蛋白酶 4 降低收费-类似/白细胞介素-1 受体信号,以及规管先天免疫激活。 The Journal of Biological Chemistry. Jan, 2012 | Pubmed ID: 22262844 TGFβ 信号和心血管疾病。 International Journal of Biological Sciences. 2012 | Pubmed ID: 22253564 TGF-β 在肝脏疾病的进展。 Cell and Tissue Research. Jan, 2012 | Pubmed ID: 22006249 骨形态发生蛋白-7 抑制 TGF-β 诱导通过整合素 β(3) 表达抑制乳腺癌细胞的入侵。 Cellular Oncology (Dordrecht). Feb, 2012 | Pubmed ID: 21935711 血管内皮细胞可塑性的 TGF-β 的规管。 Cell and Tissue Research. Jan, 2012 | Pubmed ID: 21866313 与年龄相关变化的骨性关节炎 TGF-β 信号。 Cell and Tissue Research. Jan, 2012 | Pubmed ID: 21638205 TGF-β 的内皮屏障功能调节 I 型受体 ALK5: 收缩机制和热休克蛋白 90 的潜在作用。 Journal of Cellular Physiology. Feb, 2012 | Pubmed ID: 21465483 单元格类型的肌肉生长抑制素信号的具体规定。 The FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Dec, 2011 | Pubmed ID: 22202673 时空 Smad7 转基因诱导小鼠表皮中的加速皮肤创面愈合。 The American Journal of Pathology. Oct, 2011 | Pubmed ID: 21944279 GSK3β 灭活的镇压 C-myb 功能诱导白血病细胞凋亡。 Molecular Biology of the Cell. Sep, 2011 | Pubmed ID: 21795403 控制血管生成的两个独特 TGF-β ⅰ 型受体信号通路。 Histology and Histopathology. Sep, 2011 | Pubmed ID: 21751154 探索反-TGF-β 疗法在癌症和纤维化。 Growth Factors (Chur, Switzerland). Aug, 2011 | Pubmed ID: 21718111 提升转化生长因子 β 和丝裂素活化蛋白激酶通路调解肝纤维化性状的特伦病成纤维细胞。 Fibrogenesis & Tissue Repair. 2011 | Pubmed ID: 21711521 TGF-β 受体信号通路中血管生成 ;抗血管生成治疗的新目标。 Current Pharmaceutical Biotechnology. May, 2011 | Pubmed ID: 21619534 双相的转化生长因子 β 对骨形态发生蛋白诱导成骨细胞分化的影响。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2011 | Pubmed ID: 21611961 Tgfβ/Alk5 信号是必需的胚胎血管内皮细胞诱导的剪应力 Klf2 表达式。 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Jul, 2011 | Pubmed ID: 21604321 双外显子跳绳在肌肉生长抑制素和抗肌萎缩蛋白的假肥大型肌营养不良症。 BMC Medical Genomics. 2011 | Pubmed ID: 21507246 TGF-β 信号在乳腺癌细胞入侵和骨转移。 Journal of Mammary Gland Biology and Neoplasia. Jun, 2011 | Pubmed ID: 21494783 TGF-β1/ALK5 诱导单核细胞迁移涉及肌醇和 P38 通路,并不会产生负面影响糖尿病。 Cardiovascular Research. Aug, 2011 | Pubmed ID: 21478266 Fas 相关因子 1 拮抗 Wnt 信号通过促进 β-连环素降解。 Molecular Biology of the Cell. May, 2011 | Pubmed ID: 21411632 原发性纤毛缺乏素数剪切诱导的内皮细胞的间质过渡。 Circulation Research. Apr, 2011 | Pubmed ID: 21393577 Endoglin 促进硬皮病成纤维细胞 TGF-β/Smad1 信号。 Journal of Cellular Physiology. Dec, 2011 | Pubmed ID: 21344387 ALK2 突变与唐氏综合征和先天性心脏病病人的缺陷。 European Journal of Human Genetics : EJHG. Apr, 2011 | Pubmed ID: 21248739 TGFbeta 激活丝和应力活化蛋白激酶 1 (MSK1) 以减轻细胞死亡。 The Journal of Biological Chemistry. Feb, 2011 | Pubmed ID: 21106525 TGF-β 在肿瘤中的动态角色。 The Journal of Pathology. Jan, 2011 | Pubmed ID: 20957627 激活素 A 诱导平滑肌细胞 TGF-β 与非肝纤维化表型。 Experimental Cell Research. Jan, 2011 | Pubmed ID: 20955695 骨形态发生蛋白拮抗剂提高分化和改善营养不良性型 DMD 小鼠模型。 Neurobiology of Disease. Feb, 2011 | Pubmed ID: 20940052 TGF-β/Smad 通路诱导乳腺癌细胞侵袭通过上调基质金属蛋白酶 2 和 9 的球体入侵模型系统中。 Breast Cancer Research and Treatment. Aug, 2011 | Pubmed ID: 20821046 双相的转化生长因子-β 对骨形态发生蛋白诱导成骨细胞分化的影响。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Dec, 2010 | Pubmed ID: 21162084 构骨形态发生蛋白的活性测定方法第一类受体。 Methods in Enzymology. 2010 | Pubmed ID: 21036238 硬化骨形态发生蛋白和 Wnt 信号通路的抑制作用的独特方式。 The Journal of Biological Chemistry. Dec, 2010 | Pubmed ID: 20952383 由血管的形态发生和疾病 TGF-β 家族成员的信号。 Trends in Cell Biology. Sep, 2010 | Pubmed ID: 20656490 在肿瘤细胞侵袭前转录信号的集成。 Cell Cycle (Georgetown, Tex.). Jul, 2010 | Pubmed ID: 20647778 高架 TGFbeta Smad 信号实验 Pkd1 模型和多囊肾病患者蛋白。 The Journal of Pathology. Sep, 2010 | Pubmed ID: 20549648 C-君/AP-1 二聚体原位接近结扎术检测显示更高的水平的 C-Jun/Fra1 配合物在侵略性乳腺癌细胞株体外和体内。 Molecular & Cellular Proteomics : MCP. Sep, 2010 | Pubmed ID: 20511396 基质金属蛋白酶-14 (MT1-基质金属蛋白酶)-介导的 Endoglin 脱落抑制肿瘤血管生成。 Cancer Research. May, 2010 | Pubmed ID: 20424116 膜联蛋白 A1 调节 TGF-β 信号并促进转移基底样乳腺癌细胞的形成。 Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20308542 TMEPAI,一跨膜的 TGF-β 可诱导蛋白质,固 Smad 蛋白的 TGF-β 信号转导的积极参与。 Molecular Cell. Jan, 2010 | Pubmed ID: 20129061 遗传及药理活性的激活素受体样激酶 1 针对损害血管生成和肿瘤生长。 The Journal of Experimental Medicine. Jan, 2010 | Pubmed ID: 20065063 鉴定的一个关键的残留物介导骨形态发生蛋白 (BMP)-6 抗性脑袋抑制允许工程 BMPs 与上级促活动。 The Journal of Biological Chemistry. Apr, 2010 | Pubmed ID: 20048150 ALK2 R206H 突变挂钩进行性骨化赋予本构活动到 BMP 的 I 型受体和间充质细胞向骨形态发生蛋白诱导成骨细胞分化和骨形成的增敏作用。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2010 | Pubmed ID: 19929436 5-氨基水杨酸对抑制 TGF Beta1 在大肠癌细胞中的信号。 Cancer Letters. Jan, 2010 | Pubmed ID: 19541409 自分泌骨形态发生蛋白-9 信号是通过激活素受体样激酶-2/Smad1/Smad4 促进卵巢癌细胞增殖。 Cancer Research. Dec, 2009 | Pubmed ID: 19996292 VEGF 和抑制剂 TGFbeta 类型-我受体激酶协同促进血管形成诱导 Alpha5 整合素的表达。 Journal of Cell Science. Sep, 2009 | Pubmed ID: 19706683 Smad3 是转化生长因子 β 在 Nme 小鼠乳腺上皮细胞信号转导的关键非冗余调解员。 Molecular Cancer Research : MCR. Aug, 2009 | Pubmed ID: 19671686 Endoglin Haploinsufficiency 可以减少辐射诱导的纤维化与毛细血管扩张形成的鼠标肾脏。 Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. Sep, 2009 | Pubmed ID: 19576647 ALK2 等位基因显性负将与先天性心脏病相关联。 Circulation. Jun, 2009 | Pubmed ID: 19506109 转化生长因子-β 信号转导与肿瘤血管形成。 Frontiers in Bioscience : a Journal and Virtual Library. 2009 | Pubmed ID: 19482591 从表达 ALK5 L45 循环变异 Smad 激活中有缺陷的敲入小鼠胚胎的穷人血管形成。 Laboratory Investigation; a Journal of Technical Methods and Pathology. Jul, 2009 | Pubmed ID: 19398960 电离辐射转移排头-1/ID-1 平衡并激活 Notch 途径在血管内皮细胞。 International Journal of Radiation Oncology, Biology, Physics. Feb, 2009 | Pubmed ID: 19147015 TGF-β 信号在血管生物学和功能障碍。 Cell Research. Jan, 2009 | Pubmed ID: 19114994 滑雪 Co-repressor 配合维护 TGF-β 的目标基因,SMAD7,通过 HDAC3 和 PRMT5 的基底压抑的状态。 Genes to Cells : Devoted to Molecular & Cellular Mechanisms. Jan, 2009 | Pubmed ID: 19032343 转化生长因子 β 诱导内皮细胞的间质过渡: 切换到心脏纤维化吗? Trends in Cardiovascular Medicine. Nov, 2008 | Pubmed ID: 19345316 Smad1 通路系统性硬化成纤维细胞激活,并且有针对性的由甲磺酸伊马替尼。 Arthritis and Rheumatism. Aug, 2008 | Pubmed ID: 18668566 在散发性大肠癌多数被灭活骨形态发生蛋白通路。 Gastroenterology. May, 2008 | Pubmed ID: 18471510 黏蛋白是关键皮稳压的 TGF-β 信号。 The EMBO Journal. Apr, 2008 | Pubmed ID: 18337748 ALK1 反对 ALK5/Smad3 信号转导和细胞外基质成分在软骨细胞中的表达。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jun, 2008 | Pubmed ID: 18333754 L 和 S Endoglin 差异调节 TGFbeta1 信号介导 ALK1 和 ALK5 L6E9 成肌细胞中。 Journal of Cell Science. Mar, 2008 | Pubmed ID: 18303046 骨源性硬化蛋白抑制骨形成: 其骨形态发生蛋白和 Wnt 信号作用。 The Journal of Bone and Joint Surgery. American Volume. Feb, 2008 | Pubmed ID: 18292354 Endoglin 在血管生成及血管疾病。 Angiogenesis. 2008 | Pubmed ID: 18283546 两种新型 II 受体调解 BMP 信号,并须建立斑马鱼的左右不对称。 Developmental Biology. Mar, 2008 | Pubmed ID: 18222420 转化生长因子 β 和人类胆脂瘤愈合的伤口。 The Laryngoscope. Jan, 2008 | Pubmed ID: 17989584 补偿性信号诱导中卵黄囊血管 TGFbeta 受体在小鼠中删除。 Journal of Cell Science. Dec, 2007 | Pubmed ID: 18029401 TGF-β 和骨形成蛋白 7 在肿瘤进展和骨转移中的相互作用。 Clinical & Experimental Metastasis. 2007 | Pubmed ID: 18008174 TGFbeta 讯号血管发育与疾病中的胞外控制。 Nature Reviews. Molecular Cell Biology. Nov, 2007 | Pubmed ID: 17895899 快速和灵敏生物测量骨形态发生蛋白活性。 BMC Cell Biology. 2007 | Pubmed ID: 17880711 骨形态发生蛋白 7 在发展和妇女患乳腺癌骨转移瘤的治疗。 Cancer Research. Sep, 2007 | Pubmed ID: 17875715 骨形成蛋白 7,人类前列腺癌、 上皮稳态指认调节器是一种强效抑制剂体内的前列腺癌骨转移。 The American Journal of Pathology. Sep, 2007 | Pubmed ID: 17724140 音速刺猬调解员的转化生长因子 β 诱导: Smad3 依赖活化的体外和体内的 Gli2 和 Gli1 表达式。 Cancer Research. Jul, 2007 | Pubmed ID: 17638910 通过 ALK5 信号转导介导内皮细胞 TGF-β 诱导的内皮素-1 表达: 迁移和增殖的作用。 Journal of Cell Science. Apr, 2007 | Pubmed ID: 17376964 转化生长因子-β 受体类型依赖的纤维化基因程序通过 Smad1 和 ERK1/2 的通路激活介导的。 The Journal of Biological Chemistry. Apr, 2007 | Pubmed ID: 17317656 负向调控 TGF-β 受体/Smad 信号转导。 Current Opinion in Cell Biology. Apr, 2007 | Pubmed ID: 17317136 异常 Bmp 信号和脊索发病机制中的分层食管闭锁。 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Mar, 2007 | Pubmed ID: 17260385 在胚胎及新生儿心血管发育期间,应用表达式仅限于大动脉。 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Feb, 2007 | Pubmed ID: 17195180 KLF2 抑制 TGF-β 信号通过 Smad7 的诱导和抑制作用的 AP 1 内皮细胞中。 Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2007 | Pubmed ID: 17194892 Wnt 但不是 BMP 信号参与硬化对 BMP 刺激骨形成蛋白的抑制作用。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jan, 2007 | Pubmed ID: 17032150 Smad6 由 N-甲基转移酶 1 蛋白精氨酸甲基化。 FEBS Letters. Dec, 2006 | Pubmed ID: 17118358 Endoglin 在血液细胞介导的血管修复具有关键的作用。 Circulation. Nov, 2006 | Pubmed ID: 17088457 要澄清的动力学和鲁棒性 TGF-β 通路率方程方法。 Biophysical Journal. Dec, 2006 | Pubmed ID: 17012329 Smad7 致连环退化改变表皮附属物发展。 Developmental Cell. Sep, 2006 | Pubmed ID: 16950122 Id1 TGF-β 诱导的大鼠肝星状细胞诱导分化中是关键的调解人。 Hepatology (Baltimore, Md.). May, 2006 | Pubmed ID: 16628634 Smad7 和蛋白磷酸酶 1alpha 是持续时间的 TGF-β/ALK1 在血管内皮细胞信号转导的关键决定因素。 BMC Cell Biology. 2006 | Pubmed ID: 16571110 抑癌 Smad4 是转化生长因子 β 诱导上皮向间质过渡和骨转移乳腺癌细胞所必需的。 Cancer Research. Feb, 2006 | Pubmed ID: 16489022 转化生长因子-β 的信号转导血管生成及血管疾病。 Chest. Dec, 2005 | Pubmed ID: 16373850 Deubiquitinating 酶 UCH37 Smads 进行交互,以及规管 TGF-β 信号。 Oncogene. Dec, 2005 | Pubmed ID: 16027725 依赖于 3 的 Smad2 TGF-β 信号生活小鼠的全球分析揭示了对损伤的突出组织特异性反应。 Journal of Immunology (Baltimore, Md. : 1950). Jul, 2005 | Pubmed ID: 15972691 转化生长因子-beta1 到骨。 Endocrine Reviews. Oct, 2005 | Pubmed ID: 15901668 应用/硬化,骨细胞源性的骨形成负调节器。 Cytokine & Growth Factor Reviews. Jun, 2005 | Pubmed ID: 15869900 皮肤先天免疫的新机制: 信号调节激酶 1 介导角质形成细胞分化调节 β-防御素、 LL37 和 TLR2 的表达。 European Journal of Immunology. Jun, 2005 | Pubmed ID: 15864780 TGF-β 受体功能的内皮细胞。 Cardiovascular Research. Feb, 2005 | Pubmed ID: 15664386 有缺陷的旁分泌信号由 TGFbeta Endoglin 基因突变小鼠卵黄囊血管: 一个遗传性出血性毛细血管扩张症的典范。 Development (Cambridge, England). Dec, 2004 | Pubmed ID: 15548578 Endoglin 促进血管内皮细胞增殖和 TGF-β/ALK1 信号转导。 The EMBO Journal. Oct, 2004 | Pubmed ID: 15385967 结缔组织生长因子的表达及 Smad 信号期间鼠标心发展和心肌梗死。 Developmental Dynamics : an Official Publication of the American Association of Anatomists. Nov, 2004 | Pubmed ID: 15376321 时空的 Smad1 和 Smad5 在体内激活: 监测 Smad 蛋白的转录活性。 Journal of Cell Science. Sep, 2004 | Pubmed ID: 15331632 无线电,一种新型的 Ras 蛋白,是消极调节诱导 TGF-β 的转录活性立即早期转化生长因子-β (TGF-β) 目标基因。 The Biochemical Journal. Oct, 2004 | Pubmed ID: 15239668 TGF-β-Smad 信号的新见解。 Trends in Biochemical Sciences. May, 2004 | Pubmed ID: 15130563 硬化蛋白是骨细胞表达负面的骨形成,但不是古典的 BMP 拮调节器。 The Journal of Experimental Medicine. Mar, 2004 | Pubmed ID: 15024046 神经生长因子介导的 PC12 细胞 Smad 通路的激活。 European Journal of Biochemistry / FEBS. Mar, 2004 | Pubmed ID: 15009204 骨形态发生蛋白受体的控制单元格的命运。 Molecular and Cellular Endocrinology. Dec, 2003 | Pubmed ID: 14656483 激活素受体样蛋白激酶 (ALK) 1 是拮抗横向 TGFbeta/ALK5 信号调解。 Molecular Cell. Oct, 2003 | Pubmed ID: 14580334 控制由 TGFBeta 家庭成员的间充质干细胞分化。 Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association. 2003 | Pubmed ID: 14557946 骨形态发生蛋白在成骨细胞分化的信号转导。 The Journal of Bone and Joint Surgery. American Volume. 2003 | Pubmed ID: 12925607 骨形态发生蛋白的基因阵列分析第一类受体诱导成骨细胞分化。 Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research. Jul, 2003 | Pubmed ID: 12854827 Smad7 可避免激活的肝星状细胞和大鼠肝纤维化。 Gastroenterology. Jul, 2003 | Pubmed ID: 12851882 核因子 YY1 抑制转化生长因子 β 和骨形态发生蛋白诱导细胞分化。 Molecular and Cellular Biology. Jul, 2003 | Pubmed ID: 12808092 分布的磷酸化 Smad2 标识 TGF β 配体在小鼠发育中靶组织。 Gene Expression Patterns : GEP. Jun, 2003 | Pubmed ID: 12799085 DSmurf 有选择性地降低 Decapentaplegic 激活 MAD,并扰乱了形象性光盘发展及其高效表达。 The Journal of Biological Chemistry. Jul, 2003 | Pubmed ID: 12754252 Smad 蛋白和 TGF-β 信号在血管平滑肌肉细胞。 International Journal of Molecular Medicine. May, 2003 | Pubmed ID: 12684705 合成三萜类化合物提高转化生长因子 β/Smad 信号。 Cancer Research. Mar, 2003 | Pubmed ID: 12649201 转化生长因子-beta1 (TGF-β)-诱导的细胞凋亡的前列腺癌的 TGF-β 激活激酶 1 与丝裂素活化蛋白激酶在 3 涉及 Smad7 依赖 P38 的激活。 Molecular Biology of the Cell. Feb, 2003 | Pubmed ID: 12589052 生长分化因子-9 诱导 Smad2 激活和抑制素 B 生产颗粒黄体细胞。 The Journal of Clinical Endocrinology and Metabolism. Feb, 2003 | Pubmed ID: 12574210 转化生长因子-β 1 基因突变中通过改变激活或突变蛋白质分泌增加信号 Camurati-英格曼疾病导致。 The Journal of Biological Chemistry. Feb, 2003 | Pubmed ID: 12493741 澄清 Smad 要求中转化生长因子 β ⅰ 型受体诱导的反应。 The Journal of Biological Chemistry. Feb, 2003 | Pubmed ID: 12446693 BMP 通路都参与耳胶囊形成和上皮细胞信号转导在发展中国家的鸡内耳。 Developmental Biology. Nov, 2002 | Pubmed ID: 12435365 骨形态发生蛋白 Id1 表达的刺激是充分和必要的骨形态发生蛋白诱导激活内皮细胞。 Circulation. Oct, 2002 | Pubmed ID: 12390958 成骨蛋白 (OP-1) 和其受体在兔关节软骨细胞的免疫组织化学定位。 The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. Oct, 2002 | Pubmed ID: 12364567 激活素和骨形态发生蛋白信号通路 Smad 蛋白在诱导卵巢颗粒细胞抑制素 B 生产中的参与。 Molecular and Cellular Endocrinology. Sep, 2002 | Pubmed ID: 12354674 骨形态发生蛋白/Smad 信号在支气管上皮细胞在气道炎症的激活。 American Journal of Respiratory Cell and Molecular Biology. Aug, 2002 | Pubmed ID: 12151307 Smad7 表达结果中多个上皮组织严重病理改变。 The EMBO Journal. Jun, 2002 | Pubmed ID: 12032071 转化生长因子 β 信号转导。 Journal of Leukocyte Biology. May, 2002 | Pubmed ID: 11994497 平衡内皮细胞通过两个不同的激活状态 TGF-β ⅰ 型受体。 The EMBO Journal. Apr, 2002 | Pubmed ID: 11927558 Smad 蛋白细胞增殖的调节。 Journal of Cellular Physiology. Apr, 2002 | Pubmed ID: 11920677 有缺陷的 Smad7 表达: 假定分子的缺陷,在硬皮病。 Proceedings of the National Academy of Sciences of the United States of America. Mar, 2002 | Pubmed ID: 11904440 BMP 的行动范围由其 N 终端基本氨基酸核心定义。 Current Biology : CB. Feb, 2002 | Pubmed ID: 11839272 物理和功能神经系统 3 和 Smad3 之间的互动使神经系统目标基因调控 TGF-β。 Current Biology : CB. Jan, 2002 | Pubmed ID: 11790301 自分泌 TGF-β 信号的瞬态中断导致增强的生存和潜在单一原始人类造血祖细胞的增殖。 Journal of Immunology (Baltimore, Md. : 1950). Jan, 2002 | Pubmed ID: 11777969 鉴定及其功能不同的极为重要的骨形态发生蛋白-特定响应要素 Id1 启动子。 The Journal of Biological Chemistry. Feb, 2002 | Pubmed ID: 11729207 Deubiquitinase Activity Profiling Identifies UCHL1 As a Candidate Oncoprotein That Promotes TGFβ-Induced Breast Cancer Metastasis Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. | Pubmed ID: 31857432 TGF-β介质到中微过渡(末端MT)和使用CRISPR/Cas9基因编辑对末端效应器的功能评估 Jin Ma1,2, Gerard van der Zon1,2, Gonzalo Sanchez-Duffhues1, Peter ten Dijke1,2 1Dept. Cell Chemical Biology, Leiden University Medical Center, 2Oncode Institute, Leiden University Medical Center JoVE 62198 Biology 研究TGF-β信号和TGF-β引起的乳腺癌和正常细胞的上皮到中位过渡 Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 Cancer Research 在斑马鱼胚胎人乳腺癌细胞的侵袭行为 Jiang Ren*1, Sijia Liu*1, Chao Cui1, Peter ten Dijke1 1Department of Molecular Cell Biology, Cancer Genomics Centre Netherlands, Leiden University Medical Center JoVE 55459 Cancer Research 球体的检测,以测量TGF -β诱导的入侵 Hildegonda P.H. Naber1, Eliza Wiercinska1, Peter ten Dijke1, Theo van Laar1 1Department of Molecular Cell Biology and Centre for Biomedial Genetics, Leiden University Medical Centre JoVE 3337 Medicine
TGF-β介质到中微过渡(末端MT)和使用CRISPR/Cas9基因编辑对末端效应器的功能评估 Jin Ma1,2, Gerard van der Zon1,2, Gonzalo Sanchez-Duffhues1, Peter ten Dijke1,2 1Dept. Cell Chemical Biology, Leiden University Medical Center, 2Oncode Institute, Leiden University Medical Center JoVE 62198 Biology
研究TGF-β信号和TGF-β引起的乳腺癌和正常细胞的上皮到中位过渡 Jing Zhang1, Midory Thorikay1, Gerard van der Zon1, Maarten van Dinther1, Peter ten Dijke1 1Oncode Institute and Department of Cell Chemical Biology, Leiden University Medical Center JoVE 61830 Cancer Research
在斑马鱼胚胎人乳腺癌细胞的侵袭行为 Jiang Ren*1, Sijia Liu*1, Chao Cui1, Peter ten Dijke1 1Department of Molecular Cell Biology, Cancer Genomics Centre Netherlands, Leiden University Medical Center JoVE 55459 Cancer Research
球体的检测,以测量TGF -β诱导的入侵 Hildegonda P.H. Naber1, Eliza Wiercinska1, Peter ten Dijke1, Theo van Laar1 1Department of Molecular Cell Biology and Centre for Biomedial Genetics, Leiden University Medical Centre JoVE 3337 Medicine