Phillip D. Zamore Department of Biochemistry & Molecular Pharmacology and Howard Hughes Medical Institute University of Massachusetts Medical School Biography Publications Institution JoVE Articles Phillip D. Zamore has not added a biography. If you are Phillip D. Zamore and would like to personalize this page please email our Author Liaison for assistance. Publications Sustained MiRNA-mediated Knockdown of Mutant AAT With Simultaneous Augmentation of Wild-type AAT Has Minimal Effect on Global Liver MiRNA Profiles Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2012 | Pubmed ID: 22252449 Adaptation to P Element Transposon Invasion in Drosophila Melanogaster Cell. Dec, 2011 | Pubmed ID: 22196730 Heterotypic PiRNA Ping-Pong Requires Qin, a Protein with Both E3 Ligase and Tudor Domains Molecular Cell. Nov, 2011 | Pubmed ID: 22099305 The 3'-to-5' Exoribonuclease Nibbler Shapes the 3' Ends of MicroRNAs Bound to Drosophila Argonaute1 Current Biology : CB. Nov, 2011 | Pubmed ID: 22055293 Argonaute Protein Identity and Pairing Geometry Determine Cooperativity in Mammalian RNA Silencing RNA (New York, N.Y.). Oct, 2011 | Pubmed ID: 21878547 Argonaute Proteins Current Biology : CB. Jun, 2011 | Pubmed ID: 21683893 A 5'-uridine Amplifies MiRNA/miRNA* Asymmetry in Drosophila by Promoting RNA-induced Silencing Complex Formation Silence. 2011 | Pubmed ID: 21649885 Phosphate and R2D2 Restrict the Substrate Specificity of Dicer-2, an ATP-driven Ribonuclease Molecular Cell. Apr, 2011 | Pubmed ID: 21419681 MicroRNA-regulated, Systemically Delivered RAAV9: a Step Closer to CNS-restricted Transgene Expression Molecular Therapy : the Journal of the American Society of Gene Therapy. Mar, 2011 | Pubmed ID: 21179009 Deep Annotation of Drosophila Melanogaster MicroRNAs Yields Insights into Their Processing, Modification, and Emergence Genome Research. Feb, 2011 | Pubmed ID: 21177969 Target RNA-directed Tailing and Trimming Purifies the Sorting of Endo-siRNAs Between the Two Drosophila Argonaute Proteins RNA (New York, N.Y.). Jan, 2011 | Pubmed ID: 21106652 Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals Cell. Dec, 2010 | Pubmed ID: 21183072 Somatic PiRNA Biogenesis The EMBO Journal. Oct, 2010 | Pubmed ID: 20924396 Target RNA-directed Trimming and Tailing of Small Silencing RNAs Science (New York, N.Y.). Jun, 2010 | Pubmed ID: 20558712 Welcome to Silence Silence. 2010 | Pubmed ID: 20226068 Sorting of Drosophila Small Silencing RNAs Partitions MicroRNA* Strands into the RNA Interference Pathway RNA (New York, N.Y.). Jan, 2010 | Pubmed ID: 19917635 SnapShot: Mouse PiRNAs, PIWI Proteins, and the Ping-pong Cycle Cell. Nov, 2009 | Pubmed ID: 19914174 SnapShot: Fly PiRNAs, PIWI Proteins, and the Ping-pong Cycle Cell. Oct, 2009 | Pubmed ID: 19879848 Huntington's Disease: Silencing a Brutal Killer Experimental Neurology. Dec, 2009 | Pubmed ID: 19786020 The Drosophila HP1 Homolog Rhino is Required for Transposon Silencing and PiRNA Production by Dual-strand Clusters Cell. Sep, 2009 | Pubmed ID: 19732946 A Role for MicroRNAs in the Drosophila Circadian Clock Genes & Development. Sep, 2009 | Pubmed ID: 19696147 Nucleus and Gene Expression Current Opinion in Cell Biology. Jun, 2009 | Pubmed ID: 19447016 MicroRNAs: Regulating a Change of Heart Circulation. Apr, 2009 | Pubmed ID: 19398677 Collapse of Germline PiRNAs in the Absence of Argonaute3 Reveals Somatic PiRNAs in Flies Cell. May, 2009 | Pubmed ID: 19395009 Five SiRNAs Targeting Three SNPs May Provide Therapy for Three-quarters of Huntington's Disease Patients Current Biology : CB. May, 2009 | Pubmed ID: 19361997 Small Silencing RNAs: an Expanding Universe Nature Reviews. Genetics. Feb, 2009 | Pubmed ID: 19148191 Linking SNPs to CAG Repeat Length in Huntington's Disease Patients Nature Methods. Nov, 2008 | Pubmed ID: 18931668 Design and Delivery of Antisense Oligonucleotides to Block MicroRNA Function in Cultured Drosophila and Human Cells Nature Protocols. 2008 | Pubmed ID: 18802435 Endogenous SiRNAs Derived from Transposons and MRNAs in Drosophila Somatic Cells Science (New York, N.Y.). May, 2008 | Pubmed ID: 18403677 Argonaute Loading Improves the 5' Precision of Both MicroRNAs and Their MiRNA* Strands in Flies Current Biology : CB. Jan, 2008 | Pubmed ID: 18207740 Small Silencing RNAs Current Biology : CB. Sep, 2007 | Pubmed ID: 17878043 Beginning to Understand MicroRNA Function Cell Research. Aug, 2007 | Pubmed ID: 17694094 Sorting of Drosophila Small Silencing RNAs Cell. Jul, 2007 | Pubmed ID: 17662944 Drosophila MicroRNAs Are Sorted into Functionally Distinct Argonaute Complexes After Production by Dicer-1 Cell. Jul, 2007 | Pubmed ID: 17662943 The Drosophila RNA Methyltransferase, DmHen1, Modifies Germline PiRNAs and Single-stranded SiRNAs in RISC Current Biology : CB. Jul, 2007 | Pubmed ID: 17604629 RNA Silencing: Genomic Defence with a Slice of Pi Nature. Apr, 2007 | Pubmed ID: 17443172 RNA Interference: Big Applause for Silencing in Stockholm Cell. Dec, 2006 | Pubmed ID: 17174883 Designing SiRNA That Distinguish Between Genes That Differ by a Single Nucleotide PLoS Genetics. Sep, 2006 | Pubmed ID: 16965178 A Distinct Small RNA Pathway Silences Selfish Genetic Elements in the Germline Science (New York, N.Y.). Jul, 2006 | Pubmed ID: 16809489 Rethinking the Microprocessor Cell. Jun, 2006 | Pubmed ID: 16751089 Passenger-strand Cleavage Facilitates Assembly of SiRNA into Ago2-containing RNAi Enzyme Complexes Cell. Nov, 2005 | Pubmed ID: 16271386 MicroPrimer: the Biogenesis and Function of MicroRNA Development (Cambridge, England). Nov, 2005 | Pubmed ID: 16224044 Ribo-gnome: the Big World of Small RNAs Science (New York, N.Y.). Sep, 2005 | Pubmed ID: 16141061 Normal MicroRNA Maturation and Germ-line Stem Cell Maintenance Requires Loquacious, a Double-stranded RNA-binding Domain Protein PLoS Biology. Jul, 2005 | Pubmed ID: 15918770 Perspective: Machines for RNAi Genes & Development. Mar, 2005 | Pubmed ID: 15741316 MicroRNA Biogenesis: Drosha Can't Cut It Without a Partner Current Biology : CB. Jan, 2005 | Pubmed ID: 15668159 A Protein Sensor for SiRNA Asymmetry Science (New York, N.Y.). Nov, 2004 | Pubmed ID: 15550672 A Single Argonaute Protein Mediates Both Transcriptional and Posttranscriptional Silencing in Schizosaccharomyces Pombe Genes & Development. Oct, 2004 | Pubmed ID: 15371329 MicroRNA Control of PHABULOSA in Leaf Development: Importance of Pairing to the MicroRNA 5' Region The EMBO Journal. Aug, 2004 | Pubmed ID: 15282547 Kinetic Analysis of the RNAi Enzyme Complex Nature Structural & Molecular Biology. Jul, 2004 | Pubmed ID: 15170178 The RNA-induced Silencing Complex is a Mg2+-dependent Endonuclease Current Biology : CB. May, 2004 | Pubmed ID: 15120070 RISC Assembly Defects in the Drosophila RNAi Mutant Armitage Cell. Mar, 2004 | Pubmed ID: 15035985 Plant RNAi: How a Viral Silencing Suppressor Inactivates SiRNA Current Biology : CB. Mar, 2004 | Pubmed ID: 15028237 Sequence-specific Inhibition of Small RNA Function PLoS Biology. Apr, 2004 | Pubmed ID: 15024405 Biochemical Dissection of RNA Silencing in Plants Methods in Molecular Biology (Clifton, N.J.). 2004 | Pubmed ID: 14770009 Asymmetry in the Assembly of the RNAi Enzyme Complex Cell. Oct, 2003 | Pubmed ID: 14567917 Selective Silencing by RNAi of a Dominant Allele That Causes Amyotrophic Lateral Sclerosis Aging Cell. Aug, 2003 | Pubmed ID: 12934714 In Vitro Analysis of RNA Interference in Drosophila Melanogaster Methods (San Diego, Calif.). Aug, 2003 | Pubmed ID: 12828947 SiRNAs Knock Down Hepatitis Nature Medicine. Mar, 2003 | Pubmed ID: 12612573 A Biochemical Framework for RNA Silencing in Plants Genes & Development. Jan, 2003 | Pubmed ID: 12514099 Evidence That SiRNAs Function As Guides, Not Primers, in the Drosophila and Human RNAi Pathways Molecular Cell. Sep, 2002 | Pubmed ID: 12408822 Modular Recognition of RNA by a Human Pumilio-homology Domain Cell. Aug, 2002 | Pubmed ID: 12202039 A MicroRNA in a Multiple-turnover RNAi Enzyme Complex Science (New York, N.Y.). Sep, 2002 | Pubmed ID: 12154197 Ancient Pathways Programmed by Small RNAs Science (New York, N.Y.). May, 2002 | Pubmed ID: 12016303 Why Do MiRNAs Live in the MiRNP? Genes & Development. May, 2002 | Pubmed ID: 12000786 RNAi: Nature Abhors a Double-strand Current Opinion in Genetics & Development. Apr, 2002 | Pubmed ID: 11893497 के अलगाव ड्रोसोफिला मेलानोगास्टर Testes Phillip D. Zamore1, Shengmei Ma1 1Department of Biochemistry & Molecular Pharmacology and Howard Hughes Medical Institute, University of Massachusetts Medical School JoVE 2641 Biology
के अलगाव ड्रोसोफिला मेलानोगास्टर Testes Phillip D. Zamore1, Shengmei Ma1 1Department of Biochemistry & Molecular Pharmacology and Howard Hughes Medical Institute, University of Massachusetts Medical School JoVE 2641 Biology