Ralf Schirrmacher Department of Oncology University of Alberta Biography Publications Institution JoVE Articles Ralf Schirrmacher has not added a biography. If you are Ralf Schirrmacher and would like to personalize this page please email our Author Liaison for assistance. Publications First-in-Human Brain Imaging of [F]TRACK, a PET Tracer for Tropomyosin Receptor Kinases ACS Chemical Neuroscience. Jun, 2019 | Pubmed ID: 31017386 Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging Pharmaceuticals (Basel, Switzerland). Jan, 2019 | Pubmed ID: 30609832 IEDDA Conjugation Reaction in Radiometal Labeling of Peptides with Ga and Cu: Unexpected Findings ACS Omega. Oct, 2018 | Pubmed ID: 30411057 Design, Synthesis, In Vitro, and Initial In Vivo Evaluation of Heterobivalent Peptidic Ligands Targeting Both NPY(Y₁)- and GRP-Receptors-An Improvement for Breast Cancer Imaging? Pharmaceuticals (Basel, Switzerland). Jul, 2018 | Pubmed ID: 29973529 Design, Synthesis and In vitro Evaluation of Heterobivalent Peptidic Radioligands Targeting Both GRP- and VPAC-Receptors Concomitantly Overexpressed on Various Malignancies - Is the Concept Feasible? European Journal of Medicinal Chemistry. Jul, 2018 | Pubmed ID: 29864700 Gastrin-Releasing Peptide Receptor- and Prostate-Specific Membrane Antigen-Specific Ultrasmall Gold Nanoparticles for Characterization and Diagnosis of Prostate Carcinoma Via Fluorescence Imaging Bioconjugate Chemistry. 05, 2018 | Pubmed ID: 29542916 Recent Advances in F Radiochemistry: A Focus on B-F, Si-F, Al-F, and C-F Radiofluorination Via Spirocyclic Iodonium Ylides Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 04, 2018 | Pubmed ID: 29284673 Identification of [F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging Journal of Medicinal Chemistry. 02, 2018 | Pubmed ID: 29257860 F-Radiolabeling and In Vivo Analysis of SiFA-Derivatized Polymeric Core-Shell Nanoparticles Bioconjugate Chemistry. 01, 2018 | Pubmed ID: 29202229 Synthesis, in Vitro and in Vivo Evaluation of F-fluoronorimatinib As Radiotracer for Imatinib-sensitive Gastrointestinal Stromal Tumors Nuclear Medicine and Biology. 02, 2018 | Pubmed ID: 29175467 Automated Synthesis of PET Radiotracers by Copper-mediated F-fluorination of Organoborons: Importance of the Order of Addition and Competing Protodeborylation Journal of Labelled Compounds & Radiopharmaceuticals. 03, 2018 | Pubmed ID: 29143408 Small Prosthetic Groups in F-Radiochemistry: Useful Auxiliaries for the Design of F-PET Tracers Seminars in Nuclear Medicine. 09, 2017 | Pubmed ID: 28826522 A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human Journal of Medicinal Chemistry. 08, 2017 | Pubmed ID: 28696690 Design and Synthesis of a Fluorinated Quinazoline-based Type-II Trk Inhibitor As a Scaffold for PET Radiotracer Development Bioorganic & Medicinal Chemistry Letters. 06, 2017 | Pubmed ID: 28476569 Tropomyosin Receptor Kinase Inhibitors: an Updated Patent Review for 2010-2016 - Part II Expert Opinion on Therapeutic Patents. Jul, 2017 | Pubmed ID: 28270021 Tropomyosin Receptor Kinase Inhibitors: an Updated Patent Review for 2010-2016 - Part I Expert Opinion on Therapeutic Patents. Jun, 2017 | Pubmed ID: 28270010 Radiosynthesis and Preclinical Evaluation of F-Fluoroglycosylated Octreotate for Somatostatin Receptor Imaging Bioconjugate Chemistry. Nov, 2016 | Pubmed ID: 27715017 From Unorthodox to Established: The Current Status of (18)F-Trifluoroborate- and (18)F-SiFA-Based Radiopharmaceuticals in PET Nuclear Imaging Bioconjugate Chemistry. Feb, 2016 | Pubmed ID: 26566577 Evaluation of WO2015042088 A1 - a Novel Urea-based Scaffold for TrkA Inhibition Expert Opinion on Therapeutic Patents. 2016 | Pubmed ID: 26561352 Recent Advances in the Development and Application of Radiolabeled Kinase Inhibitors for PET Imaging Molecules (Basel, Switzerland). Dec, 2015 | Pubmed ID: 26690113 Improving the Stability of Peptidic Radiotracers by the Introduction of Artificial Scaffolds: Which Structure Element is Most Useful? Journal of Labelled Compounds & Radiopharmaceuticals. Aug, 2015 | Pubmed ID: 26219022 In Vivo Evaluation of ¹⁸F-SiFAlin-Modified TATE: A Potential Challenge for ⁶⁸Ga-DOTATATE, the Clinical Gold Standard for Somatostatin Receptor Imaging with PET Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. Jul, 2015 | Pubmed ID: 25977461 5-(4-((4-[(18)F]Fluorobenzyl)oxy)-3-methoxybenzyl)pyrimidine-2,4-diamine: a Selective Dual Inhibitor for Potential PET Imaging of Trk/CSF-1R Bioorganic & Medicinal Chemistry Letters. Oct, 2014 | Pubmed ID: 25257201 ¹⁸F-labeled Silicon-based Fluoride Acceptors: Potential Opportunities for Novel Positron Emitting Radiopharmaceuticals BioMed Research International. 2014 | Pubmed ID: 25157357 18 F-labeling van Radiotracers Functionaliseerde met een Siliciumfluoride acceptor (SiFA) voor positron emissie tomografie David Connolly*1, Justin J. Bailey*1, Harun Ilhan2,3, Peter Bartenstein2,3, Carmen Wängler4, Björn Wängler5, Melinda Wuest1, Frank Wuest1, Ralf Schirrmacher1 1Department of Oncology, University of Alberta, 2Department of Nuclear Medicine, University Hospital of Munich, 3ENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, LMU Munich, 4Biomedical Chemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University, 5Molecular Imaging and Radiochemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University JoVE 60623 Chemistry
18 F-labeling van Radiotracers Functionaliseerde met een Siliciumfluoride acceptor (SiFA) voor positron emissie tomografie David Connolly*1, Justin J. Bailey*1, Harun Ilhan2,3, Peter Bartenstein2,3, Carmen Wängler4, Björn Wängler5, Melinda Wuest1, Frank Wuest1, Ralf Schirrmacher1 1Department of Oncology, University of Alberta, 2Department of Nuclear Medicine, University Hospital of Munich, 3ENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System, LMU Munich, 4Biomedical Chemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University, 5Molecular Imaging and Radiochemistry, Department of Clinical Radiology and Nuclear Medicine, Medical Faculty Mannheim of Heidelberg University JoVE 60623 Chemistry