Ran Zhuang Department of Immunology Fourth Military Medical University Biography Publications Institution JoVE Articles Ran Zhuang has not added a biography. If you are Ran Zhuang and would like to personalize this page please email our Author Liaison for assistance. Publications Interleukin-6 Absence Triggers Intestinal Microbiota Dysbiosis and Mucosal Immunity in Mice Cytokine. May, 2022 | Pubmed ID: 35276634 CD226 Knockout Alleviates High-fat Diet Induced Obesity by Suppressing Proinflammatory Macrophage Phenotype Journal of Translational Medicine. 11, 2021 | Pubmed ID: 34823548 [Preparation and Identification of Mouse-derived Monoclonal Antibodies to Human ST2 Molecule] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. Nov, 2021 | Pubmed ID: 34809742 Acute Cold Water-Immersion Restraint Stress Induces Intestinal Injury and Reduces the Diversity of Gut Microbiota in Mice Frontiers in Cellular and Infection Microbiology. 2021 | Pubmed ID: 34722327 CD226 Deficiency Promotes Glutaminolysis and Alleviates Mitochondria Damage in Vascular Endothelial Cells Under Hemorrhagic Shock FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 11, 2021 | Pubmed ID: 34669985 Platelet-mediated Tumor Metastasis Mechanism and the Role of Cell Adhesion Molecules Critical Reviews in Oncology/hematology. Nov, 2021 | Pubmed ID: 34662726 CD226 Is Required to Maintain Megakaryocytes/Platelets Homeostasis in the Treatment of Knee Osteoarthritis With Platelet-Rich Plasma in Mice Frontiers in Pharmacology. 2021 | Pubmed ID: 34526904 GDF15 Induces Immunosuppression Via CD48 on Regulatory T Cells in Hepatocellular Carcinoma Journal for Immunotherapy of Cancer. 09, 2021 | Pubmed ID: 34489334 Elevated Plasma Fractalkine Level Is Associated with the Severity of Hemorrhagic Fever with Renal Syndrome in Humans Viral Immunology. 09, 2021 | Pubmed ID: 34463135 Adiponectin's Globular Domain Inhibits T Cell Activation by Interacting with LAIR-1 Biochemical and Biophysical Research Communications. 10, 2021 | Pubmed ID: 34403808 Silencing of HuR Inhibits Osteosarcoma Cell Epithelial-Mesenchymal Transition AGO2 in Association With Long Non-Coding RNA XIST Frontiers in Oncology. 2021 | Pubmed ID: 33816232 Splenectomy Improves Liver Fibrosis Via Tumor Necrosis Factor Superfamily 14 (LIGHT) Through the JNK/TGF-β1 Signaling Pathway Experimental & Molecular Medicine. 03, 2021 | Pubmed ID: 33654222 [Preparation and Application of Mouse-derived Monoclonal Antibodies Against Mouse CD226] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. Oct, 2020 | Pubmed ID: 33148389 Protective CD8 T-cell Response Against Hantaan Virus Infection Induced by Immunization with Designed Linear Multi-epitope Peptides in HLA-A2.1/K Transgenic Mice Virology Journal. 10, 2020 | Pubmed ID: 33028368 LAIR-1 Overexpression Inhibits Epithelial-mesenchymal Transition in Osteosarcoma Via GLUT1-related Energy Metabolism World Journal of Surgical Oncology. Jun, 2020 | Pubmed ID: 32563267 [Exploration and Practice of Online Teaching System of Medical Immunology Based on Small Private Online Course (SPOC) Model During Coronavirus Disease 2019 (COVID-19) Pandemic] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. Apr, 2020 | Pubmed ID: 32519674 [The Conditional Knockout of CD226 Gene Reduces Acute Lung Injury in Mice with Hemorrhagic Shock] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. Feb, 2020 | Pubmed ID: 32314710 ADAR1 Alleviates Inflammation in a Murine Sepsis Model Via the ADAR1-miR-30a-SOCS3 Axis Mediators of Inflammation. 2020 | Pubmed ID: 32273831 Deficiency of Platelet Adhesion Molecule CD226 Causes Megakaryocyte Development and Platelet Hyperactivity FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 05, 2020 | Pubmed ID: 32248623 CD226 Deficiency on Regulatory T Cells Aggravates Renal Fibrosis Via Up-regulation of Th2 Cytokines Through MiR-340 Journal of Leukocyte Biology. 04, 2020 | Pubmed ID: 31802539 ECDI-fixed Donor Splenocytes Prolong Skin Allograft Survival by Promoting M2 Macrophage Polarization and Inducing Regulatory T Cells FASEB BioAdvances. Nov, 2019 | Pubmed ID: 32123816 [CD226 Knockout Aggravates Radiation-induced Liver Injury in Mice] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. Jan, 2019 | Pubmed ID: 30914115 CD226 is Involved in Megakaryocyte Activation and Early-stage Differentiation Molecular Immunology. 03, 2019 | Pubmed ID: 30738249 Silencing LAIR-1 in Human THP-1 Macrophage Increases Foam Cell Formation by Modulating PPARγ and M2 Polarization Cytokine. 11, 2018 | Pubmed ID: 30176557 TIGIT-Fc Alleviates Acute Graft-versus-host Disease by Suppressing CTL Activation Via Promoting the Generation of Immunoregulatory Dendritic Cells Biochimica Et Biophysica Acta. Molecular Basis of Disease. 09, 2018 | Pubmed ID: 29960041 ADAR1 Attenuates Allogeneic Graft Rejection by Suppressing MiR-21 Biogenesis in Macrophages and Promoting M2 Polarization FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. 09, 2018 | Pubmed ID: 29694248 Effects of CD100 Promote Wound Healing in Diabetic Mice Journal of Molecular Histology. Jun, 2018 | Pubmed ID: 29637382 Blocking CD226 Promotes Allogeneic Transplant Immune Tolerance and Improves Skin Graft Survival by Increasing the Frequency of Regulatory T Cells in a Murine Model Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 2018 | Pubmed ID: 29550821 Novel Identified HLA-A*0201-Restricted Hantaan Virus Glycoprotein Cytotoxic T-Cell Epitopes Could Effectively Induce Protective Responses in HLA-A2.1/K Transgenic Mice May Associate with the Severity of Hemorrhagic Fever with Renal Syndrome Frontiers in Immunology. 2017 | Pubmed ID: 29312318 Elevated Plasma Growth Arrest-Specific 6 Protein Levels Are Associated with the Severity of Disease During Hantaan Virus Infection in Humans Viral Immunology. 06, 2017 | Pubmed ID: 28537534 Sustained High Levels of Both Total and High Molecular Weight Adiponectin in Plasma During the Convalescent Phase of Haemorrhagic Fever with Renal Syndrome Are Associated with Disease Severity Journal of Immunology Research. 2017 | Pubmed ID: 28424792 Structure and Function of HLA-A*02-Restricted Hantaan Virus Cytotoxic T-Cell Epitope That Mediates Effective Protective Responses in HLA-A2.1/K(b) Transgenic Mice Frontiers in Immunology. 2016 | Pubmed ID: 27551282 Specially Modified Stromal and Immune Microenvironment in Injected Bone marrow Following Intrabone Transplantation Facilitates Allogeneic hematopoietic Stem Cell Engraftment Experimental Hematology. 07, 2016 | Pubmed ID: 27090963 CD226 Reduces Endothelial Cell Glucose Uptake Under Hyperglycemic Conditions with Inflammation in Type 2 Diabetes Mellitus Oncotarget. Mar, 2016 | Pubmed ID: 26910838 COMP-Ang1 Promotes Long-term Survival of Allogeneic Islet Grafts in a Bioinert Perforated Chamber by Inhibiting Inflammation Via Inhibition of the TLR4 Signaling Pathway Biotechnology Letters. Jun, 2016 | Pubmed ID: 26875093 CD8low CD100- T Cells Identify a Novel CD8 T Cell Subset Associated with Viral Control During Human Hantaan Virus Infection Journal of Virology. Dec, 2015 | Pubmed ID: 26378166 Elevated Plasma Soluble CD14 Levels Correlate with the Monocyte Response Status During Hantaan Virus Infection in Humans Viral Immunology. Oct, 2015 | Pubmed ID: 26196589 Hantaan Virus Infection Induces Both Th1 and ThGranzyme B+ Cell Immune Responses That Associated with Viral Control and Clinical Outcome in Humans PLoS Pathogens. Apr, 2015 | Pubmed ID: 25836633 Soluble Scavenger Receptor CD163 Is Associated with Severe Acute Kidney Injury in Patients with Hantaan Virus Infection Viral Immunology. May, 2015 | Pubmed ID: 25789628 IL-33/ST2 Correlates with Severity of Haemorrhagic Fever with Renal Syndrome and Regulates the Inflammatory Response in Hantaan Virus-infected Endothelial Cells PLoS Neglected Tropical Diseases. Feb, 2015 | Pubmed ID: 25658420 UPR Decreases CD226 Ligand CD155 Expression and Sensitivity to NK Cell-mediated Cytotoxicity in Hepatoma Cells European Journal of Immunology. Dec, 2014 | Pubmed ID: 25209846 Increased Plasma Cell-free DNA Level During HTNV Infection: Correlation with Disease Severity and Virus Load Viruses. Jul, 2014 | Pubmed ID: 25029493 Hantaan Virus Infection Induces CXCL10 Expression Through TLR3, RIG-I, and MDA-5 Pathways Correlated with the Disease Severity Mediators of Inflammation. 2014 | Pubmed ID: 24701034 The Role of LAIR-1 (CD305) in T Cells and Monocytes/macrophages in Patients with Rheumatoid Arthritis Cellular Immunology. Jan, 2014 | Pubmed ID: 24380839 Elevated Plasma Soluble Sema4D/CD100 Levels Are Associated with Disease Severity in Patients of Hemorrhagic Fever with Renal Syndrome PloS One. 2013 | Pubmed ID: 24040126 Expression of Leukocyte-associated Immunoglobulin-like Receptor-1 (LAIR-1) on Osteoclasts and Its Potential Role in Rheumatoid Arthritis Clinics (Sao Paulo, Brazil). Apr, 2013 | Pubmed ID: 23778340 HLA-A2 and B35 Restricted Hantaan Virus Nucleoprotein CD8+ T-cell Epitope-specific Immune Response Correlates with Milder Disease in Hemorrhagic Fever with Renal Syndrome PLoS Neglected Tropical Diseases. 2013 | Pubmed ID: 23469304 Interleukin-17 Plays a Critical Role in the Acute Rejection of Intestinal Transplantation World Journal of Gastroenterology. Feb, 2013 | Pubmed ID: 23429965 Heterogeneous Expression of CT10, CT45 and GAGE7 Antigens and Their Prognostic Significance in Human Breast Carcinoma Japanese Journal of Clinical Oncology. Mar, 2013 | Pubmed ID: 23315387 Sustained High Level of Serum VEGF at Convalescent Stage Contributes to the Renal Recovery After HTNV Infection in Patients with Hemorrhagic Fever with Renal Syndrome Clinical & Developmental Immunology. 2012 | Pubmed ID: 23097674 The Genetic Polymorphisms of HLA Are Strongly Correlated with the Disease Severity After Hantaan Virus Infection in the Chinese Han Population Clinical & Developmental Immunology. 2012 | Pubmed ID: 23091554 Plexin-B1: a Potential Diagnostic Biomarker for Glioma and a Future Target for Glioma Immunotherapy Journal of Neuroimmunology. Nov, 2012 | Pubmed ID: 22939532 Identification of a Novel B-cell Epitope of Hantaan Virus Glycoprotein Recognized by Neutralizing 3D8 Monoclonal Antibody The Journal of General Virology. Dec, 2012 | Pubmed ID: 22933664 Establishment of Reverse Direct ELISA and Its Application in Screening High-affinity Monoclonal Antibodies Hybridoma (2005). Aug, 2012 | Pubmed ID: 22894783 MiR-30c-1* Promotes Natural Killer Cell Cytotoxicity Against Human Hepatoma Cells by Targeting the Transcription Factor HMBOX1 Cancer Science. Feb, 2012 | Pubmed ID: 22320217 Cystatin C, a Novel Urinary Biomarker for Sensitive Detection of Acute Kidney Injury During Haemorrhagic Fever with Renal Syndrome Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. Aug, 2010 | Pubmed ID: 20450259 [Study on the Effect of CD4+CD25+ Regulatory T Cell Adoptive Transfusion on Humoral Immune Function in Rat Composite Tissue Allotransplantation Model] Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. Jan, 2010 | Pubmed ID: 20302759 Increased Levels of Soluble CD226 in Sera Accompanied by Decreased Membrane CD226 Expression on Peripheral Blood Mononuclear Cells from Cancer Patients BMC Immunology. Jun, 2009 | Pubmed ID: 19490613 Expression of CD226 Antagonizes Apoptotic Cell Death in Murine Thymocytes Journal of Immunology (Baltimore, Md. : 1950). May, 2009 | Pubmed ID: 19380793 Application of Sandwich ELISA for Detecting Tag Fusion Proteins in High Throughput Applied Microbiology and Biotechnology. Nov, 2008 | Pubmed ID: 18818915 Generation of Monoclonal Antibodies Against Escherichia Coli DsbA Hybridoma (2005). Apr, 2008 | Pubmed ID: 18642678 Purification of GFP Fusion Proteins with High Purity and Yield by Monoclonal Antibody-coupled Affinity Column Chromatography Protein Expression and Purification. May, 2008 | Pubmed ID: 18342538 [Preparation and Characterization of Monoclonal Antibodies Against Human CD112 (Nectin2/PRR2)] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. Apr, 2007 | Pubmed ID: 17428395 Dynamic Changes of Apoptosis-inducing Ligands and Th1/Th2 Like Subpopulations in Hantaan Virus-induced Hemorrhagic Fever with Renal Syndrome Clinical Immunology (Orlando, Fla.). Jun, 2006 | Pubmed ID: 16616877 Generation of Monoclonal Antibodies to Cancer/testis (CT) Antigen CT10/MAGE-C2 Cancer Immunity. Apr, 2006 | Pubmed ID: 16594646 [Preparation, Purification and Identification of the Rabbit Antibody Against Extracellular Region of MLAIR-1] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. Sep, 2005 | Pubmed ID: 16143065 [Regulation of Soluble TRAIL and Membrane TRAIL in Jurkat Cells by PMA] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. May, 2005 | Pubmed ID: 15862138 Expression Pattern of Epithelial Cell Adhesion Molecule on Normal and Malignant Colon Tissues World Journal of Gastroenterology. Jan, 2005 | Pubmed ID: 15637741 [Apoptosis-inducing Ligand TRAIL Can Be Recruited to Lipid Rafts] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. Jan, 2005 | Pubmed ID: 15629071 [Changes and Significance of TNF, SIL-2R, IL-6, IL-4 and IFN-gamma Levels in Plasma from the Patients with Hemorrhagic Fever with Renal Syndrome] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. Nov, 2004 | Pubmed ID: 15555451 [Cloning, Prokaryotic Expression of LAIR and Identification of Their Immunological Reactivities] Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi = Chinese Journal of Cellular and Molecular Immunology. Mar, 2003 | Pubmed ID: 15151743 عزل الخلايا اللمفاوية الفطرية من المجموعة 2 من الغشاء المخاطي للأنف في الفأر للكشف عن تعبير CD226 Yang Xie*1, Yuan Zhang*2, Yitian Liu3, Yuling Wang4, Kun Cheng4, Ran Zhuang4, Ka Bian1 1Otolaryngological Department of Tangdu Hospital, Fourth Military Medical University, 2Institute of Medical Research, Northwestern Polytechnical University, 3Orthopedic Department of Tangdu Hospital, Fourth Military Medical University, 4Department of Immunology, Fourth Military Medical University JoVE 63525 Immunology and Infection
عزل الخلايا اللمفاوية الفطرية من المجموعة 2 من الغشاء المخاطي للأنف في الفأر للكشف عن تعبير CD226 Yang Xie*1, Yuan Zhang*2, Yitian Liu3, Yuling Wang4, Kun Cheng4, Ran Zhuang4, Ka Bian1 1Otolaryngological Department of Tangdu Hospital, Fourth Military Medical University, 2Institute of Medical Research, Northwestern Polytechnical University, 3Orthopedic Department of Tangdu Hospital, Fourth Military Medical University, 4Department of Immunology, Fourth Military Medical University JoVE 63525 Immunology and Infection