Sabine Gerbal-Chaloin Institute for Regenerative Medicine and Biotherapy (IRMB), INSERM U1183 Montpellier University Biography Publications Institution JoVE Articles Sabine Gerbal-Chaloin has not added a biography. If you are Sabine Gerbal-Chaloin and would like to personalize this page please email our Author Liaison for assistance. Publications Activation of the Constitutive Androstane Receptor Induces Hepatic Lipogenesis and Regulates Pnpla3 Gene Expression in a LXR-independent Way Toxicology and Applied Pharmacology. Jul, 2016 | Pubmed ID: 27180240 Skatole (3-Methylindole) Is a Partial Aryl Hydrocarbon Receptor Agonist and Induces CYP1A1/2 and CYP1B1 Expression in Primary Human Hepatocytes PloS One. 2016 | Pubmed ID: 27138278 The Pregnane X Receptor Down-regulates Organic Cation Transporter 1 (SLC22A1) in Human Hepatocytes by Competing for ("squelching") SRC-1 Coactivator British Journal of Pharmacology. May, 2016 | Pubmed ID: 26920453 Synergistic Activation of Human Pregnane X Receptor by Binary Cocktails of Pharmaceutical and Environmental Compounds Nature Communications. Sep, 2015 | Pubmed ID: 26333997 Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of β-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling Toxicological Sciences : an Official Journal of the Society of Toxicology. Nov, 2015 | Pubmed ID: 26259606 PBPK Modeling of Irbesartan: Incorporation of Hepatic Uptake Biopharmaceutics & Drug Disposition. Nov, 2015 | Pubmed ID: 26037524 Novel Role for Carbohydrate Responsive Element Binding Protein in the Control of Ethanol Metabolism and Susceptibility to Binge Drinking Hepatology (Baltimore, Md.). Oct, 2015 | Pubmed ID: 25761756 Cold Preservation of Human Adult Hepatocytes for Liver Cell Therapy Cell Transplantation. 2015 | Pubmed ID: 25622096 The WNT/β-catenin Pathway is a Transcriptional Regulator of CYP2E1, CYP1A2, and Aryl Hydrocarbon Receptor Gene Expression in Primary Human Hepatocytes Molecular Pharmacology. Dec, 2014 | Pubmed ID: 25228302 Human Induced Pluripotent Stem Cells in Hepatology: Beyond the Proof of Concept The American Journal of Pathology. Feb, 2014 | Pubmed ID: 24269594 Nuclear Receptors in the Cross-talk of Drug Metabolism and Inflammation Drug Metabolism Reviews. Feb, 2013 | Pubmed ID: 23330545 Dissecting the First Transcriptional Divergence During Human Embryonic Development Stem Cell Reviews. Mar, 2012 | Pubmed ID: 21750961 Brief Report: Benchmarking Human Pluripotent Stem Cell Markers During Differentiation into the Three Germ Layers Unveils a Striking Heterogeneity: All Markers Are Not Equal Stem Cells (Dayton, Ohio). Sep, 2011 | Pubmed ID: 21714037 Chromatin Dynamics of Gene Activation and Repression in Response to Interferon Alpha (IFN(alpha)) Reveal New Roles for Phosphorylated and Unphosphorylated Forms of the Transcription Factor STAT2 The Journal of Biological Chemistry. Jun, 2011 | Pubmed ID: 21498520 Modular Bioreactor for Primary Human Hepatocyte Culture: Medium Flow Stimulates Expression and Activity of Detoxification Genes Biotechnology Journal. May, 2011 | Pubmed ID: 21259441 Comparison of Hepatic-like Cell Production from Human Embryonic Stem Cells and Adult Liver Progenitor Cells: CAR Transduction Activates a Battery of Detoxification Genes Stem Cell Reviews. Sep, 2011 | Pubmed ID: 21210253 Human Pluripotent Stem Cells: from Biology to Cell Therapy World Journal of Stem Cells. Apr, 2010 | Pubmed ID: 21607113 Isolation and Culture of Adult Human Liver Progenitor Cells: in Vitro Differentiation to Hepatocyte-like Cells Methods in Molecular Biology (Clifton, N.J.). 2010 | Pubmed ID: 20645055 Comparative Effects of Microtubules Disruption on Glucocorticoid Receptor Functions in Proliferating and Quiescent Cells International Journal of Toxicology. May-Jun, 2010 | Pubmed ID: 20448266 The Tangle of Nuclear Receptors That Controls Xenobiotic Metabolism and Transport: Crosstalk and Consequences Annual Review of Pharmacology and Toxicology. 2008 | Pubmed ID: 17608617 Isolation, Characterization, and Differentiation to Hepatocyte-like Cells of Nonparenchymal Epithelial Cells from Adult Human Liver Stem Cells (Dayton, Ohio). Jul, 2007 | Pubmed ID: 17412893 First Step of the Cell-penetrating Peptide Mechanism Involves Rac1 GTPase-dependent Actin-network Remodelling Biology of the Cell. Apr, 2007 | Pubmed ID: 17233629 Ketoconazole and Miconazole Are Antagonists of the Human Glucocorticoid Receptor: Consequences on the Expression and Function of the Constitutive Androstane Receptor and the Pregnane X Receptor Molecular Pharmacology. Jul, 2006 | Pubmed ID: 16608920 Is Nuclear Factor Kappa-B the Missing Link Between Inflammation, Cancer and Alteration in Hepatic Drug Metabolism in Patients with Cancer? European Journal of Cancer (Oxford, England : 1990). Apr, 2006 | Pubmed ID: 16510279 Role of CYP3A4 in the Regulation of the Aryl Hydrocarbon Receptor by Omeprazole Sulphide Cellular Signalling. May, 2006 | Pubmed ID: 16109480 Design of a Novel Class of Peptide Inhibitors of Cyclin-dependent Kinase/cyclin Activation The Journal of Biological Chemistry. Apr, 2005 | Pubmed ID: 15649889 On the Mechanism of Non-endosomial Peptide-mediated Cellular Delivery of Nucleic Acids Biochimica Et Biophysica Acta. Dec, 2004 | Pubmed ID: 15581849 Interleukin 1beta Inhibits CAR-induced Expression of Hepatic Genes Involved in Drug and Bilirubin Clearance Hepatology (Baltimore, Md.). Oct, 2004 | Pubmed ID: 15382119 Pathophysiological Factors Affecting CAR Gene Expression Drug Metabolism Reviews. Nov, 2003 | Pubmed ID: 14705859 Use of Long-term Cultures of Human Hepatocytes to Study Cytochrome P450 Gene Expression Methods in Enzymology. 2002 | Pubmed ID: 12424921 Transcriptional Regulation of CYP2C9 Gene. Role of Glucocorticoid Receptor and Constitutive Androstane Receptor The Journal of Biological Chemistry. Jan, 2002 | Pubmed ID: 11679585 MitoCeption: Transferencia hermoso humano MSC mitocondrias de las células madre de glioblastoma Brice Nzigou Mombo1, Sabine Gerbal-Chaloin1, Aleksandra Bokus1, Martine Daujat-Chavanieu1, Christian Jorgensen1, Jean-Philippe Hugnot2, Marie-Luce Vignais1 1Institute for Regenerative Medicine and Biotherapy (IRMB), INSERM U1183, Montpellier University, 2Institute of Neurosciences of Montpellier (INM), INSERM U1051, Montpellier University JoVE 55245 Biology
MitoCeption: Transferencia hermoso humano MSC mitocondrias de las células madre de glioblastoma Brice Nzigou Mombo1, Sabine Gerbal-Chaloin1, Aleksandra Bokus1, Martine Daujat-Chavanieu1, Christian Jorgensen1, Jean-Philippe Hugnot2, Marie-Luce Vignais1 1Institute for Regenerative Medicine and Biotherapy (IRMB), INSERM U1183, Montpellier University, 2Institute of Neurosciences of Montpellier (INM), INSERM U1051, Montpellier University JoVE 55245 Biology