Sarah E Coupland Liverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine University of Liverpool Biography Publications Institution JoVE Articles Sarah E Coupland has not added a biography. If you are Sarah E Coupland and would like to personalize this page please email our Author Liaison for assistance. Publications A Possible Role for Hepcidin in the Detection of Iron Deficiency in Severely Anaemic HIV-infected Patients in Malawi PloS One. 2020 | Pubmed ID: 32107492 Severe Anaemia Complicating HIV in Malawi; Multiple Co-existing Aetiologies Are Associated with High Mortality PloS One. 2020 | Pubmed ID: 32097440 Multicenter External Validation of the Liverpool Uveal Melanoma Prognosticator Online: An OOG Collaborative Study Cancers. Feb, 2020 | Pubmed ID: 32085617 Lenalidomide, Dexamethasone and Alemtuzumab or Ofatumumab in High-risk Chronic Lymphocytic Leukaemia: Final Results of the NCRI CLL210 Trial Haematologica. Feb, 2020 | Pubmed ID: 32054653 Effects of Plaque Brachytherapy and Proton Beam Radiotherapy on Prognostic Testing: a Comparison of Uveal Melanoma Genotyped by Microsatellite Analysis The British Journal of Ophthalmology. Feb, 2020 | Pubmed ID: 32024655 Concomitant Orbital Tumours: Small Lymphocytic Lymphoma Involving the Lacrimal Gland of a Patient with Clinical Diagnoses of Muir-Torre Syndrome and Extensive Sebaceous Gland Carcinoma of the Ipsilateral Eyelid Ocular Oncology and Pathology. Jan, 2020 | Pubmed ID: 32002399 Software-assisted Decision Support in Digital Histopathology The Journal of Pathology. Jan, 2020 | Pubmed ID: 31994192 Loss of BAP1 Expression is Associated with an Immunosuppressive Microenvironment in Uveal Melanoma, with Implications for Immunotherapy Development The Journal of Pathology. Apr, 2020 | Pubmed ID: 31960425 Importance of Partial Losses of Chromosome 3 in Uveal Melanoma in the BAP1 Gene Region JAMA Ophthalmology. Jan, 2020 | Pubmed ID: 31895426 Features of Ectopic Lymphoid-like Structures in Human Uveitis Experimental Eye Research. Feb, 2020 | Pubmed ID: 31877281 Genome-wide Study on Uveal Melanoma Patients Finds Association to DNA Repair Gene TDP1 Melanoma Research. Apr, 2020 | Pubmed ID: 31626034 International Multicentre Retrospective Cohort Study of Ocular Adnexal Marginal Zone B-cell Lymphoma The British Journal of Ophthalmology. Mar, 2020 | Pubmed ID: 31177189 Clinical and Genomic Features of Adult and Paediatric Acute Leukaemias with Ophthalmic Manifestations BMJ Open Ophthalmology. 2019 | Pubmed ID: 31673633 CM-Path Molecular Diagnostics Forum-consensus Statement on the Development and Implementation of Molecular Diagnostic Tests in the United Kingdom British Journal of Cancer. Oct, 2019 | Pubmed ID: 31575975 The Potential Use of Electrochemotherapy in the Treatment of Uveal Melanoma: In Vitro Results in 3D Tumor Cultures and In Vivo Results in a Chick Embryo Model Cancers. Sep, 2019 | Pubmed ID: 31514412 So Close, Yet So Far: Discrepancies Between Uveal and Other Melanomas. A Position Paper from UM Cure 2020 Cancers. Jul, 2019 | Pubmed ID: 31336679 Diagnosis of Orbital Mass Lesions: Clinical, Radiological, and Pathological Recommendations Survey of Ophthalmology. Nov - Dec, 2019 | Pubmed ID: 31276737 CD166high Uveal Melanoma Cells Represent a Subpopulation With Enhanced Migratory Capacity Investigative Ophthalmology & Visual Science. 06, 2019 | Pubmed ID: 31242292 Lacrimal Sac Sebaceous Carcinoma Ophthalmic Plastic and Reconstructive Surgery. Jul/Aug, 2019 | Pubmed ID: 30921057 Conjunctival Melanoma Copy Number Alterations and Correlation with Mutation Status, Tumor Features, and Clinical Outcome Pigment Cell & Melanoma Research. 07, 2019 | Pubmed ID: 30672666 Proceedings of the Association for Research in Vision and Ophthalmology and Champalimaud Foundation Ocular Oncogenesis and Oncology Conference Translational Vision Science & Technology. Jan, 2019 | Pubmed ID: 30652059 Conjunctival Melanoma and Electrochemotherapy: Preliminary Results Using 2D and 3D Cell Culture Models In vitro Acta Ophthalmologica. Jun, 2019 | Pubmed ID: 30548215 Orbital Lymphoma-An International Multicenter Retrospective Study American Journal of Ophthalmology. 03, 2019 | Pubmed ID: 30419193 Detection of Mutations in SF3B1, EIF1AX and GNAQ in Primary Orbital Melanoma by Candidate Gene Analysis BMC Cancer. Dec, 2018 | Pubmed ID: 30558566 Accessibility to and Quality of Human Eye Tissue for Research: A Cross-Sectional Survey of ARVO Members Investigative Ophthalmology & Visual Science. 10, 2018 | Pubmed ID: 30304462 Prognostication of Metastatic Death in Uveal Melanoma Patients: A Markov Multi-state Model Computers in Biology and Medicine. 11, 2018 | Pubmed ID: 30278339 Women in Vision UK Strive for Gender Equality in Ophthalmology and Vision Sciences Therapeutic Advances in Ophthalmology. Jan-Dec, 2018 | Pubmed ID: 29998223 Recent Breakthroughs in Metastatic Uveal Melanoma: a Cause for Optimism? Future Oncology (London, England). Jun, 2018 | Pubmed ID: 29741103 [Primary Vitreoretinal Lymphoma] Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft. 04, 2018 | Pubmed ID: 29589147 Re: Reddy Et al.: Vitrectomy and Vitrector Port Needle Biopsy of Choroidal Melanoma for Gene Expression Profile Testing Immediately Before Brachytherapy. (Ophthalmology. 2017;124:1377-1382) Ophthalmology. 04, 2018 | Pubmed ID: 29566876 Patterns of BAP1 Protein Expression Provide Insights into Prognostic Significance and the Biology of Uveal Melanoma The Journal of Pathology. Clinical Research. Jan, 2018 | Pubmed ID: 29416875 Multiple Primary Malignancies and Prolonged Survival in a Patient with Widespread Metastatic Cutaneous Melanoma Melanoma Research. 04, 2018 | Pubmed ID: 29346178 Nestin Expression in Primary and Metastatic Uveal Melanoma - Possible Biomarker for High-risk Uveal Melanoma Acta Ophthalmologica. Aug, 2018 | Pubmed ID: 29338117 Combined Mutation and Copy-number Variation Detection by Targeted Next-generation Sequencing in Uveal Melanoma Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc. 05, 2018 | Pubmed ID: 29327717 Kinome-wide Transcriptional Profiling of Uveal Melanoma Reveals New Vulnerabilities to Targeted Therapeutics Pigment Cell & Melanoma Research. 03, 2018 | Pubmed ID: 28972303 Clinicopathological Features of Ocular Adnexal Mantle-Cell Lymphoma in an International Multicenter Cohort JAMA Ophthalmology. 12, 2017 | Pubmed ID: 29121219 Chronic Lymphocytic Leukaemia/ Small-Cell Lymphocytic Lymphoma of the Lacrimal Sac: A Case Series Ocular Oncology and Pathology. Sep, 2017 | Pubmed ID: 29071273 Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma Cancer Cell. Aug, 2017 | Pubmed ID: 28810145 Inflammatory Cell Infiltrates in Advanced Metastatic Uveal Melanoma Human Pathology. 08, 2017 | Pubmed ID: 28655639 Fucoidan Does Not Exert Anti-Tumorigenic Effects on Uveal Melanoma Cell Lines Marine Drugs. Jun, 2017 | Pubmed ID: 28640204 Retinal and Vitreous Metastases from Hepatocholangiocarcinoma BMC Cancer. Jun, 2017 | Pubmed ID: 28629380 Prognostic Biopsy of Choroidal Melanoma: an Optimised Surgical and Laboratory Approach The British Journal of Ophthalmology. 08, 2017 | Pubmed ID: 28596284 Primary Vitreoretinal Lymphoma -- A Review Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.). May-Jun, 2017 | Pubmed ID: 28558176 Incorporating Clinical, Histological, and Genetic Parameters for Choroidal Melanoma Prognostication JAMA Ophthalmology. 07, 2017 | Pubmed ID: 28542696 RasGRP3 Mediates MAPK Pathway Activation in GNAQ Mutant Uveal Melanoma Cancer Cell. 05, 2017 | Pubmed ID: 28486107 Lacrimal Sac Tumors--A Review Asia-Pacific Journal of Ophthalmology (Philadelphia, Pa.). Mar-Apr, 2017 | Pubmed ID: 28399337 Vitreous MicroRNA Levels As Diagnostic Biomarkers for Vitreoretinal Lymphoma Blood. 06, 2017 | Pubmed ID: 28389463 Recurrent Chordoma with Orbital and Eyelid Invasion Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. 07, 2017 | Pubmed ID: 28357494 Adipophilin Expression in Primary and Metastatic Uveal Melanoma: a Pilot Study Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. 05, 2017 | Pubmed ID: 28299438 Lymphoma of the Eyelid - An International Multicenter Retrospective Study American Journal of Ophthalmology. May, 2017 | Pubmed ID: 28209503 Two Different Tumours in the Same Eye Clinical & Experimental Ophthalmology. Apr, 2017 | Pubmed ID: 27574099 External Validation of the Liverpool Uveal Melanoma Prognosticator Online Investigative Ophthalmology & Visual Science. Nov, 2016 | Pubmed ID: 27835710 Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors Cancer Research. 12, 2016 | Pubmed ID: 27742686 Diffuse Histiocytic Sarcoma Involving the Choroid JAMA Ophthalmology. 10, 2016 | Pubmed ID: 27541306 Genetic Variants of the BTNL2 Gene in Uveal Melanoma JAMA Ophthalmology. 10, 2016 | Pubmed ID: 27533527 Metastatic Ocular Melanoma to the Liver Exhibits Infiltrative and Nodular Growth Patterns Human Pathology. 11, 2016 | Pubmed ID: 27476775 In-depth Proteomic Profiling of the Uveal Melanoma Secretome Oncotarget. Aug, 2016 | Pubmed ID: 27391064 Prognostic Biopsy of Choroidal Melanoma After Proton Beam Radiation Therapy Ophthalmology. 10, 2016 | Pubmed ID: 27324683 Minimal Contribution of ERK1/2-MAPK Signalling Towards the Maintenance of Oncogenic GNAQQ209P-driven Uveal Melanomas in Zebrafish Oncotarget. Jun, 2016 | Pubmed ID: 27166257 How We Diagnose and Treat Vitreoretinal Lymphoma British Journal of Haematology. Jun, 2016 | Pubmed ID: 27133587 Genetic Findings in Treatment-naïve and Proton-beam-radiated Iris Melanomas The British Journal of Ophthalmology. 07, 2016 | Pubmed ID: 27098748 Lacrimal Gland Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue-type Associated with Massive Amyloid Deposition Acta Ophthalmologica. Nov, 2016 | Pubmed ID: 27010357 Conjunctival Lymphoma--An International Multicenter Retrospective Study JAMA Ophthalmology. Apr, 2016 | Pubmed ID: 26891973 Perforin Expression in Eyelid Sebaceous Carcinomas: a Useful and Specific Immunomarker for the Differential Diagnosis of Eyelid Carcinomas Acta Ophthalmologica. Aug, 2016 | Pubmed ID: 26843360 Insights into Genetic Alterations of Liver Metastases from Uveal Melanoma Pigment Cell & Melanoma Research. Jan, 2016 | Pubmed ID: 26523470 High Frequency of Malignant Transformation of Ovarian Mature Teratoma into Squamous Cell Carcinoma in Young Patients in Northeast Brazil International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. Mar, 2016 | Pubmed ID: 26367783 Non-ocular Primary Malignancies in Patients with Uveal Melanoma: the Liverpool Experience The British Journal of Ophthalmology. Mar, 2016 | Pubmed ID: 26178903 Use of the Chick Embryo Model in Uveal Melanoma Ocular Oncology and Pathology. Apr, 2015 | Pubmed ID: 27171889 Bilateral Diffuse Uveal Melanocytic Proliferation: Molecular Genetic Analysis of a Case and Review of the Literature Ocular Oncology and Pathology. Dec, 2015 | Pubmed ID: 27171825 Core Endoresection As Neoadjuvant Treatment of Uveal Melanoma Ocular Oncology and Pathology. Dec, 2015 | Pubmed ID: 27171344 Evaluation of High-Throughput Genomic Assays for the Fc Gamma Receptor Locus PloS One. 2015 | Pubmed ID: 26545243 Retinochoroidal Toxoplasmosis in a Patient with Cerebral Post-transplant Lymphoproliferative Disease of Hodgkin's Type: a Diagnostic Challenge Journal of Ophthalmic Inflammation and Infection. Dec, 2015 | Pubmed ID: 26239296 Concordant Chromosome 3 Results in Paired Choroidal Melanoma Biopsies and Subsequent Tumour Resection Specimens The British Journal of Ophthalmology. Oct, 2015 | Pubmed ID: 26206786 Two Distinct Uveal Melanomas in the Same Eye JAMA Ophthalmology. Sep, 2015 | Pubmed ID: 26110363 Malignant Lymphoma of the Conjunctiva Survey of Ophthalmology. Sep-Oct, 2015 | Pubmed ID: 26003619 Conjunctival Extranodal Marginal Zone B-cell Lymphoma with Crystal-storing Histiocytosis Acta Ophthalmologica. Nov, 2015 | Pubmed ID: 25988528 Immunohistochemical Analysis Indicates That the Anatomical Location of B-cell Non-Hodgkin's Lymphoma is Determined by Differentially Expressed Chemokine Receptors, Sphingosine-1-phosphate Receptors and Integrins Experimental Hematology & Oncology. 2015 | Pubmed ID: 25938000 High Frequency of MYD88 Mutations in Vitreoretinal B-cell Lymphoma: a Valuable Tool to Improve Diagnostic Yield of Vitreous Aspirates Blood. Jul, 2015 | Pubmed ID: 25900979 Pigmented Limbal Nodule Consistent With a Ciliary Body Nevus in an Organ Donor JAMA Ophthalmology. Jun, 2015 | Pubmed ID: 25790354 Cluster Analysis of Multiplex Ligation-dependent Probe Amplification Data in Choroidal Melanoma Molecular Vision. 2015 | Pubmed ID: 25684974 Ocular Adnexal Diffuse Large B-cell Lymphoma: a Multicenter International Study JAMA Ophthalmology. Feb, 2015 | Pubmed ID: 25393033 Tg(Grm1) Transgenic Mice: a Murine Model That Mimics Spontaneous Uveal Melanoma in Humans? Experimental Eye Research. Oct, 2014 | Pubmed ID: 25051141 Motility and Trafficking in B-cell Non-Hodgkin's Lymphoma (Review) International Journal of Oncology. Jul, 2014 | Pubmed ID: 24788871 Ocular Adnexal Follicular Lymphoma: a Multicenter International Study JAMA Ophthalmology. Jul, 2014 | Pubmed ID: 24763920 Choroidal Schwannoma: a Case Series of Five Patients The British Journal of Ophthalmology. Aug, 2014 | Pubmed ID: 24759877 Trans-scleral Local Resection of Toxic Choroidal Melanoma After Proton Beam Radiotherapy The British Journal of Ophthalmology. Jun, 2014 | Pubmed ID: 24568869 Does Choroidal Melanoma Regression Correlate with Chromosome 3 Loss After Ruthenium Brachytherapy? The British Journal of Ophthalmology. Jul, 2014 | Pubmed ID: 24518077 A Rare Cause of Weight Loss Gut. Jun, 2014 | Pubmed ID: 24277727 Single Nucleotide Polymorphism Array Analysis of Uveal Melanomas Reveals That Amplification of CNKSR3 is Correlated with Improved Patient Survival The American Journal of Pathology. Mar, 2013 | Pubmed ID: 23357503 Intraocular Collision Tumour: Case Report and Literature Review Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. May, 2013 | Pubmed ID: 23232651 Molecular Pathology of Uveal Melanoma Eye (London, England). Feb, 2013 | Pubmed ID: 23222563 Molecular Pathology of Lymphoma Eye (London, England). Feb, 2013 | Pubmed ID: 23222560 Ocular Melanoma Saudi Journal of Ophthalmology : Official Journal of the Saudi Ophthalmological Society. Apr, 2012 | Pubmed ID: 23960984 Proteomic Analyses of the Vitreous Humour Mediators of Inflammation. 2012 | Pubmed ID: 22973072 IL-10 -1082 SNP and IL-10 in Primary CNS and Vitreoretinal Lymphomas Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. Oct, 2012 | Pubmed ID: 22628023 Comparison of Formalin-fixed and Snap-frozen Samples Analyzed by Multiplex Ligation-dependent Probe Amplification for Prognostic Testing in Uveal Melanoma Investigative Ophthalmology & Visual Science. May, 2012 | Pubmed ID: 22427594 Analysis of Intraocular Biopsies Developments in Ophthalmology. 2012 | Pubmed ID: 22042016 Vitreous Biopsy: Specimen Preparation and Interpretation Monographs in Clinical Cytology. 2012 | Pubmed ID: 22024585 Combined P53 and MDM2 Biomarker Analysis Shows a Unique Pattern of Expression Associated with Poor Prognosis in Patients with Renal Cell Carcinoma Undergoing Radical Nephrectomy BJU International. Apr, 2012 | Pubmed ID: 21756282 HSP-27 Protein Expression in Uveal Melanoma: Correlation with Predicted Survival Acta Ophthalmologica. Sep, 2012 | Pubmed ID: 21114636 Uveal Melanoma Cell Lines Contain Stem-like Cells That Self-renew, Produce Differentiated Progeny, and Survive Chemotherapy Investigative Ophthalmology & Visual Science. Oct, 2011 | Pubmed ID: 21896849 Multiplex Ligation-dependent Probe Amplification of Conjunctival Melanoma Reveals Common BRAF V600E Gene Mutation and Gene Copy Number Changes Investigative Ophthalmology & Visual Science. Jul, 2011 | Pubmed ID: 21693616 Multiplex Ligation-dependent Probe Amplification Analysis of Uveal Melanoma with Extraocular Extension Demonstrates Heterogeneity of Gross Chromosomal Abnormalities Investigative Ophthalmology & Visual Science. Jul, 2011 | Pubmed ID: 21659309 The Challenge of the Microenvironment in B-cell Lymphomas Histopathology. Jan, 2011 | Pubmed ID: 21261684 Genetic Heterogeneity in Uveal Melanoma Assessed by Multiplex Ligation-dependent Probe Amplification Investigative Ophthalmology & Visual Science. Oct, 2010 | Pubmed ID: 20484589 Whole-genome Microarray Detects Deletions and Loss of Heterozygosity of Chromosome 3 Occurring Exclusively in Metastasizing Uveal Melanoma Investigative Ophthalmology & Visual Science. Oct, 2010 | Pubmed ID: 20445121 Proteomics of Uveal Melanomas Suggests HSP-27 As a Possible Surrogate Marker of Chromosome 3 Loss Investigative Ophthalmology & Visual Science. Jan, 2010 | Pubmed ID: 19643972 Pathophysiology of Retinal Lymphoma Ocular Immunology and Inflammation. Jul-Aug, 2009 | Pubmed ID: 19657975 A TNM-based Clinical Staging System of Ocular Adnexal Lymphomas Archives of Pathology & Laboratory Medicine. Aug, 2009 | Pubmed ID: 19653722 Understanding Intraocular Lymphomas Clinical & Experimental Ophthalmology. Aug, 2008 | Pubmed ID: 18954321 Routes of Extraocular Extension of Uveal Melanoma: Risk Factors and Influence on Survival Probability Ophthalmology. Oct, 2008 | Pubmed ID: 18554722 The Pathologist's Perspective on Vitreous Opacities Eye (London, England). Oct, 2008 | Pubmed ID: 18344965 The Tale and Molecular Trail of a Disseminated Ocular Adnexal Malt Lymphoma Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. Jul, 2007 | Pubmed ID: 17219122 Electrochemotherapy in 3D Ocular Melanoma Spheroids using a Customized Electrode Miltiadis Fiorentzis1,2, Arne Viestenz1, Berthold Seitz3, Sarah E Coupland4, Joana Heinzelmann1 1Department of Ophthalmology, University Hospital Halle (Saale), Martin-Luther University Halle-Wittenberg, 2Department of Ophthalmology, University Hospital Essen, Duisburg Essen University, 3Department of Ophthalmology, Saarland University Medical Center, 4Liverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool JoVE 60611 Medicine
Electrochemotherapy in 3D Ocular Melanoma Spheroids using a Customized Electrode Miltiadis Fiorentzis1,2, Arne Viestenz1, Berthold Seitz3, Sarah E Coupland4, Joana Heinzelmann1 1Department of Ophthalmology, University Hospital Halle (Saale), Martin-Luther University Halle-Wittenberg, 2Department of Ophthalmology, University Hospital Essen, Duisburg Essen University, 3Department of Ophthalmology, Saarland University Medical Center, 4Liverpool Ocular Oncology Research Group, Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool JoVE 60611 Medicine