Savita Khanna Department of Surgery The Ohio State University Biography Publications Institution JoVE Articles Savita Khanna has not added a biography. If you are Savita Khanna and would like to personalize this page please email our Author Liaison for assistance. Publications Oral Tocotrienols Are Transported to Human Tissues and Delay the Progression of the Model for End-Stage Liver Disease Score in Patients The Journal of Nutrition. Feb, 2012 | Pubmed ID: 22298568 Platelet-rich Fibrin Matrix Improves Wound Angiogenesis Via Inducing Endothelial Cell Proliferation Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. Nov, 2011 | Pubmed ID: 22092846 Tocotrienols: the Lesser Known Form of Natural Vitamin E Indian Journal of Experimental Biology. Oct, 2011 | Pubmed ID: 22013739 Natural Vitamin E α-tocotrienol Protects Against Ischemic Stroke by Induction of Multidrug Resistance-associated Protein 1 Stroke; a Journal of Cerebral Circulation. Aug, 2011 | Pubmed ID: 21719775 Tocotrienol Vitamin E Protects Against Preclinical Canine Ischemic Stroke by Inducing Arteriogenesis Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Nov, 2011 | Pubmed ID: 21673716 Particulate β-glucan Induces TNF-α Production in Wound Macrophages Via a Redox-sensitive NF-κβ-dependent Pathway Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. May-Jun, 2011 | Pubmed ID: 21518092 Oxygen-inducible Glutamate Oxaloacetate Transaminase As Protective Switch Transforming Neurotoxic Glutamate to Metabolic Fuel During Acute Ischemic Stroke Antioxidants & Redox Signaling. May, 2011 | Pubmed ID: 21361730 MiR-200b Targets Ets-1 and is Down-regulated by Hypoxia to Induce Angiogenic Response of Endothelial Cells The Journal of Biological Chemistry. Jan, 2011 | Pubmed ID: 21081489 An Endovascular Canine Middle Cerebral Artery Occlusion Model for the Study of Leptomeningeal Collateral Recruitment Investigative Radiology. Jan, 2011 | Pubmed ID: 20856126 MicroRNA in Ischemic Stroke Etiology and Pathology Physiological Genomics. May, 2011 | Pubmed ID: 20841499 Significance of Brain Tissue Oxygenation and the Arachidonic Acid Cascade in Stroke Antioxidants & Redox Signaling. May, 2011 | Pubmed ID: 20673202 Alpha-lipoic Acid Does Not Alter Stress Protein Response to Acute Exercise in Diabetic Brain Cell Biochemistry and Function. Dec, 2010 | Pubmed ID: 21104931 Palm Oil-derived Natural Vitamin E Alpha-tocotrienol in Brain Health and Disease Journal of the American College of Nutrition. Jun, 2010 | Pubmed ID: 20823491 Acute Exercise and Thioredoxin-1 in Rat Brain, and Alpha-lipoic Acid and Thioredoxin-interacting Protein Response, in Diabetes International Journal of Sport Nutrition and Exercise Metabolism. Jun, 2010 | Pubmed ID: 20601738 Fra-2 Mediates Oxygen-sensitive Induction of Transforming Growth Factor Beta in Cardiac Fibroblasts Cardiovascular Research. Sep, 2010 | Pubmed ID: 20427335 Hypoxia Inducible MicroRNA 210 Attenuates Keratinocyte Proliferation and Impairs Closure in a Murine Model of Ischemic Wounds Proceedings of the National Academy of Sciences of the United States of America. Apr, 2010 | Pubmed ID: 20308562 Macrophage Dysfunction Impairs Resolution of Inflammation in the Wounds of Diabetic Mice PloS One. 2010 | Pubmed ID: 20209061 Oxygen-sensitive Outcomes and Gene Expression in Acute Ischemic Stroke Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. Jul, 2010 | Pubmed ID: 20145654 Nanomolar Vitamin E Alpha-tocotrienol Inhibits Glutamate-induced Activation of Phospholipase A2 and Causes Neuroprotection Journal of Neurochemistry. Mar, 2010 | Pubmed ID: 20028458 Micromanaging Vascular Biology: Tiny MicroRNAs Play Big Band Journal of Vascular Research. 2009 | Pubmed ID: 19571573 Characterization of a Preclinical Model of Chronic Ischemic Wound Physiological Genomics. May, 2009 | Pubmed ID: 19293328 MicroRNA Expression in Response to Murine Myocardial Infarction: MiR-21 Regulates Fibroblast Metalloprotease-2 Via Phosphatase and Tensin Homologue Cardiovascular Research. Apr, 2009 | Pubmed ID: 19147652 Diabetes Impairs Exercise Training-associated Thioredoxin Response and Glutathione Status in Rat Brain Journal of Applied Physiology (Bethesda, Md. : 1985). Feb, 2009 | Pubmed ID: 19074570 Oral Administration of Blueberry Inhibits Angiogenic Tumor Growth and Enhances Survival of Mice with Endothelial Cell Neoplasm Antioxidants & Redox Signaling. Jan, 2009 | Pubmed ID: 18817478 Neuroprotective and Antiinflammatory Properties of a Novel Demethylated Curcuminoid Antioxidants & Redox Signaling. Mar, 2009 | Pubmed ID: 18724833 Redox Modification of Ryanodine Receptors Contributes to Sarcoplasmic Reticulum Ca2+ Leak in Chronic Heart Failure Circulation Research. Dec, 2008 | Pubmed ID: 19008475 Minimally Invasive Neuroradiologic Model of Preclinical Transient Middle Cerebral Artery Occlusion in Canines Proceedings of the National Academy of Sciences of the United States of America. Sep, 2008 | Pubmed ID: 18779582 Characterization of the Acute Temporal Changes in Excisional Murine Cutaneous Wound Inflammation by Screening of the Wound-edge Transcriptome Physiological Genomics. Jul, 2008 | Pubmed ID: 18460641 Topical Oxygen Therapy Induces Vascular Endothelial Growth Factor Expression and Improves Closure of Clinically Presented Chronic Wounds Clinical and Experimental Pharmacology & Physiology. Aug, 2008 | Pubmed ID: 18430064 Evidence for the Involvement of MiRNA in Redox Regulated Angiogenic Response of Human Microvascular Endothelial Cells Arteriosclerosis, Thrombosis, and Vascular Biology. Mar, 2008 | Pubmed ID: 18258815 Redox Regulation of the VEGF Signaling Path and Tissue Vascularization: Hydrogen Peroxide, the Common Link Between Physical Exercise and Cutaneous Wound Healing Free Radical Biology & Medicine. Jan, 2008 | Pubmed ID: 18191754 Assessment of Wound-site Redox Environment and the Significance of Rac2 in Cutaneous Healing Free Radical Biology & Medicine. Feb, 2008 | Pubmed ID: 18068132 P21waf1/cip1/sdi1 As a Central Regulator of Inducible Smooth Muscle Actin Expression and Differentiation of Cardiac Fibroblasts to Myofibroblasts Molecular Biology of the Cell. Dec, 2007 | Pubmed ID: 17881730 Transcriptome-wide Analysis of Blood Vessels Laser Captured from Human Skin and Chronic Wound-edge Tissue Proceedings of the National Academy of Sciences of the United States of America. Sep, 2007 | Pubmed ID: 17728400 Transcriptome of Primary Adipocytes from Obese Women in Response to a Novel Hydroxycitric Acid-based Dietary Supplement DNA and Cell Biology. Sep, 2007 | Pubmed ID: 17708719 Tocotrienols: the Emerging Face of Natural Vitamin E Vitamins and Hormones. 2007 | Pubmed ID: 17628176 Regulation of C-Src Activity in Glutamate-induced Neurodegeneration The Journal of Biological Chemistry. Aug, 2007 | Pubmed ID: 17569670 Tocotrienols in Health and Disease: the Other Half of the Natural Vitamin E Family Molecular Aspects of Medicine. Oct-Dec, 2007 | Pubmed ID: 17507086 MicroRNA in Cutaneous Wound Healing: a New Paradigm DNA and Cell Biology. Apr, 2007 | Pubmed ID: 17465889 Alpha-lipoic Acid Modulates Heat Shock Factor-1 Expression in Streptozotocin-induced Diabetic Rat Kidney Antioxidants & Redox Signaling. Apr, 2007 | Pubmed ID: 17280490 Laser Microdissection and Capture of Pure Cardiomyocytes and Fibroblasts from Infarcted Heart Regions: Perceived Hyperoxia Induces P21 in Peri-infarct Myocytes American Journal of Physiology. Heart and Circulatory Physiology. Mar, 2007 | Pubmed ID: 17158647 Natural Vitamin E Alpha-tocotrienol: Retention in Vital Organs in Response to Long-term Oral Supplementation and Withdrawal Free Radical Research. Jul, 2006 | Pubmed ID: 16984003 Transcriptome of the Subcutaneous Adipose Tissue in Response to Oral Supplementation of Type 2 Leprdb Obese Diabetic Mice with Niacin-bound Chromium Physiological Genomics. Nov, 2006 | Pubmed ID: 16940432 Characterization of the Potent Neuroprotective Properties of the Natural Vitamin E Alpha-tocotrienol Journal of Neurochemistry. Sep, 2006 | Pubmed ID: 16923160 Heat Shock Protein 60 Response to Exercise in Diabetes: Effects of Alpha-lipoic Acid Supplementation Journal of Diabetes and Its Complications. Jul-Aug, 2006 | Pubmed ID: 16798478 Oxygen-sensitive Reset of Hypoxia-inducible Factor Transactivation Response: Prolyl Hydroxylases Tune the Biological Normoxic Set Point Free Radical Biology & Medicine. Jun, 2006 | Pubmed ID: 16785028 Postprandial Levels of the Natural Vitamin E Tocotrienol in Human Circulation Antioxidants & Redox Signaling. May-Jun, 2006 | Pubmed ID: 16771695 Regulation of Vascular Responses to Inflammation: Inducible Matrix Metalloproteinase-3 Expression in Human Microvascular Endothelial Cells is Sensitive to Antiinflammatory Boswellia Antioxidants & Redox Signaling. Mar-Apr, 2006 | Pubmed ID: 16677108 Transcriptome Analysis of the Ischemia-reperfused Remodeling Myocardium: Temporal Changes in Inflammation and Extracellular Matrix Physiological Genomics. May, 2006 | Pubmed ID: 16554547 Perceived Hyperoxia: Oxygen-induced Remodeling of the Reoxygenated Heart Cardiovascular Research. Jul, 2006 | Pubmed ID: 16483558 Tocotrienols: Vitamin E Beyond Tocopherols Life Sciences. Mar, 2006 | Pubmed ID: 16458936 Safety and Whole-body Antioxidant Potential of a Novel Anthocyanin-rich Formulation of Edible Berries Molecular and Cellular Biochemistry. Jan, 2006 | Pubmed ID: 16328973 Dermal Wound Healing is Subject to Redox Control Molecular Therapy : the Journal of the American Society of Gene Therapy. Jan, 2006 | Pubmed ID: 16126008 Wound Site Neutrophil Transcriptome in Response to Psychological Stress in Young Men Gene Expression. 2005 | Pubmed ID: 16358416 Delivery of Orally Supplemented Alpha-tocotrienol to Vital Organs of Rats and Tocopherol-transport Protein Deficient Mice Free Radical Biology & Medicine. Nov, 2005 | Pubmed ID: 16257640 Neuroprotective Properties of the Natural Vitamin E Alpha-tocotrienol Stroke; a Journal of Cerebral Circulation. Oct, 2005 | Pubmed ID: 16166580 Oxygen: from the Benefits of Inducing VEGF Expression to Managing the Risk of Hyperbaric Stress Antioxidants & Redox Signaling. Sep-Oct, 2005 | Pubmed ID: 16115043 Human Genome Screen to Identify the Genetic Basis of the Anti-inflammatory Effects of Boswellia in Microvascular Endothelial Cells DNA and Cell Biology. Apr, 2005 | Pubmed ID: 15812241 Tocotrienol: the Natural Vitamin E to Defend the Nervous System? Annals of the New York Academy of Sciences. Dec, 2004 | Pubmed ID: 15753140 Body Weight and Abdominal Fat Gene Expression Profile in Response to a Novel Hydroxycitric Acid-based Dietary Supplement Gene Expression. 2004 | Pubmed ID: 15200237 Exercise Training Modulates Heat Shock Protein Response in Diabetic Rats Journal of Applied Physiology (Bethesda, Md. : 1985). Aug, 2004 | Pubmed ID: 15075301 Proteomic Analysis of the Mammalian Cell Nucleus Methods in Enzymology. 2004 | Pubmed ID: 15063675 Survival Surgery for Coronary Occlusion and Reoxygenation in a Rodent Model Methods in Enzymology. 2004 | Pubmed ID: 15063673 Perceived Hyperoxia: Oxygen-regulated Signal Transduction Pathways in the Heart Methods in Enzymology. 2004 | Pubmed ID: 15063670 Characterization of Perceived Hyperoxia in Isolated Primary Cardiac Fibroblasts and in the Reoxygenated Heart The Journal of Biological Chemistry. Nov, 2003 | Pubmed ID: 12952964 Molecular Basis of Vitamin E Action: Tocotrienol Modulates 12-lipoxygenase, a Key Mediator of Glutamate-induced Neurodegeneration The Journal of Biological Chemistry. Oct, 2003 | Pubmed ID: 12917400 Peroxisomal Membrane Monocarboxylate Transporters: Evidence for a Redox Shuttle System? Biochemical and Biophysical Research Communications. Apr, 2003 | Pubmed ID: 12705896 Oxygen Sensing by Primary Cardiac Fibroblasts: a Key Role of P21(Waf1/Cip1/Sdi1) Circulation Research. Feb, 2003 | Pubmed ID: 12595337 Would Healing: Oxygen and Emerging Therapeutics. Columbus, Ohio, September 12-15, 2002 Antioxidants & Redox Signaling. Dec, 2002 | Pubmed ID: 12580193 Anti-angiogenic Property of Edible Berries Free Radical Research. Sep, 2002 | Pubmed ID: 12448828 Vitamin E Sensitive Genes in the Developing Rat Fetal Brain: a High-density Oligonucleotide Microarray Analysis FEBS Letters. Oct, 2002 | Pubmed ID: 12387859 Dermal Wound Healing Properties of Redox-active Grape Seed Proanthocyanidins Free Radical Biology & Medicine. Oct, 2002 | Pubmed ID: 12374620 Simultaneous Detection of Tocopherols and Tocotrienols in Biological Samples Using HPLC-coulometric Electrode Array Methods in Enzymology. 2002 | Pubmed ID: 12125359 Glutamate-induced C-Src Activation in Neuronal Cells Methods in Enzymology. 2002 | Pubmed ID: 12125347 Functional Genomics: High-density Oligonucleotide Arrays Methods in Enzymology. 2002 | Pubmed ID: 12078521 Oxygen, Oxidants, and Antioxidants in Wound Healing: an Emerging Paradigm Annals of the New York Academy of Sciences. May, 2002 | Pubmed ID: 12074976 Oxidant-induced Vascular Endothelial Growth Factor Expression in Human Keratinocytes and Cutaneous Wound Healing The Journal of Biological Chemistry. Sep, 2002 | Pubmed ID: 12068011 Copper-induced Vascular Endothelial Growth Factor Expression and Wound Healing American Journal of Physiology. Heart and Circulatory Physiology. May, 2002 | Pubmed ID: 11959648 Yüksek frekanslı Yüksek çözünürlüklü Ekokardiyografi: İskemi-Reperfüze murin Kalp Miyokard Strain, kontraktilite ve Mitral Yetmezliğinde Non-invaziv Tekrarlanan Ölçüm İlk Kanıt Surya C. Gnyawali1,2, Sashwati Roy1,2, Jason Driggs1,2, Savita Khanna1,2, Thomas Ryan2,3, Chandan K. Sen2 1Department of Surgery, The Ohio State University, 2Heart and Lung Research Institute, The Ohio State University, 3Department of Cardiovascular Medicine, The Ohio State University JoVE 1781 Medicine
Yüksek frekanslı Yüksek çözünürlüklü Ekokardiyografi: İskemi-Reperfüze murin Kalp Miyokard Strain, kontraktilite ve Mitral Yetmezliğinde Non-invaziv Tekrarlanan Ölçüm İlk Kanıt Surya C. Gnyawali1,2, Sashwati Roy1,2, Jason Driggs1,2, Savita Khanna1,2, Thomas Ryan2,3, Chandan K. Sen2 1Department of Surgery, The Ohio State University, 2Heart and Lung Research Institute, The Ohio State University, 3Department of Cardiovascular Medicine, The Ohio State University JoVE 1781 Medicine
